GB8724566D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
GB8724566D0
GB8724566D0 GB878724566A GB8724566A GB8724566D0 GB 8724566 D0 GB8724566 D0 GB 8724566D0 GB 878724566 A GB878724566 A GB 878724566A GB 8724566 A GB8724566 A GB 8724566A GB 8724566 D0 GB8724566 D0 GB 8724566D0
Authority
GB
United Kingdom
Prior art keywords
alkyl
hydrogen
image
chemical compounds
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB878724566A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roussel Laboratories Ltd
Original Assignee
Roussel Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Laboratories Ltd filed Critical Roussel Laboratories Ltd
Priority to GB878724566A priority Critical patent/GB8724566D0/en
Publication of GB8724566D0 publication Critical patent/GB8724566D0/en
Priority to ZA887433A priority patent/ZA887433B/en
Priority to JP63257426A priority patent/JPH01193274A/en
Priority to US07/259,285 priority patent/US4895863A/en
Priority to MX013455A priority patent/MX173422B/en
Priority to DK579688A priority patent/DK170024B1/en
Priority to AU23978/88A priority patent/AU613413B2/en
Priority to DE88402634T priority patent/DE3883140T2/en
Priority to CA000580679A priority patent/CA1331991C/en
Priority to ES88402634T priority patent/ES2059552T3/en
Priority to AT88402634T priority patent/ATE92928T1/en
Priority to GB8824492A priority patent/GB2211186B/en
Priority to HU885344A priority patent/HU201769B/en
Priority to EP88402634A priority patent/EP0313458B1/en
Priority to PT88795A priority patent/PT88795B/en
Priority to SU925010659A priority patent/RU2014334C1/en
Priority to GR930400671T priority patent/GR3009703T3/el
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds of formula: <IMAGE> in which R1 denotes either the group (A): <IMAGE> in which R4 and R5 are hydrogen or C1-5 alkyl, R6 is hydrogen, C1-5 alkyl, phenyl, halogen, C2-5 alkoxycarbonyl, cyano, amido, mono- or dialkylamido, or the group (B): <IMAGE> in which R7 and R8 are hydrogen, C1-5 alkyl, R2 and R3 denote: <IMAGE> in which m is 1, 2 or 3, X1 and X2 are hydrogen, alkyl, alkenyl, C5 alkoxy, aralkoxy, aryloxy, halogen, nitrile or azido or X1 and X2 together form a methylenedioxy radical, and their salts, their preparation, their application as medications and new intermediates.
GB878724566A 1987-10-20 1987-10-20 Chemical compounds Pending GB8724566D0 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GB878724566A GB8724566D0 (en) 1987-10-20 1987-10-20 Chemical compounds
ZA887433A ZA887433B (en) 1987-10-20 1988-10-04 Imidazo(1,2-b)imidazobenzothiazoles and their acids addition salts,their process and intermediates of preparation,their application as medicaments and the pharmaceutical compositions containing them
JP63257426A JPH01193274A (en) 1987-10-20 1988-10-14 Imidado(2, 1-b)benzothiazole and acid adduct thereof, production thereof, pharmaceutical composition containing the same and use thereof as drug
US07/259,285 US4895863A (en) 1987-10-20 1988-10-18 Novel imidazo[2,1-B]benzothiazoles
MX013455A MX173422B (en) 1987-10-20 1988-10-18 IMIDAZO- (2,1-B) BENZOTIAZOLES AND PROCEDURE FOR ITS PREPARATION
DK579688A DK170024B1 (en) 1987-10-20 1988-10-18 Imidazo (2,1-b) thiazole derivatives, their preparation, intermediates for use therewith, their use as pharmaceuticals and pharmaceutical compositions containing them
PT88795A PT88795B (en) 1987-10-20 1988-10-19 METHOD FOR PREPARING IMIDAZO (2,1-B) BENZO-THIAZOIS DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA000580679A CA1331991C (en) 1987-10-20 1988-10-19 Imidazo/2,1-b/benzothiazoles useful in the treatment of memory disorders and/or irritable conditions
DE88402634T DE3883140T2 (en) 1987-10-20 1988-10-19 Imidazo (2,1-b) benzothiazoles and their acid addition salts, processes and intermediates for their preparation, their use as medicaments and pharmaceutical preparations containing them.
AU23978/88A AU613413B2 (en) 1987-10-20 1988-10-19 2-substituted imidazo(2,1-b)-benzothiazoles
ES88402634T ES2059552T3 (en) 1987-10-20 1988-10-19 NEW IMIDAZO (2,1-B) BENZOTIAZOLES AND THEIR ADDITIONAL SALTS WITH ACIDS, THEIR PROCEDURE AND THE INTERMEDIATE PRODUCTS OF ITS PREPARATION, ITS APPLICATION AS MEDICINES, AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
AT88402634T ATE92928T1 (en) 1987-10-20 1988-10-19 IMIDAZO(2,1-B)BENZOTHIAZOLE AND THEIR ACID ADDITION SALTS, PROCESSES AND INTERMEDIATE PRODUCTS FOR THEIR MANUFACTURE, THEIR USE AS MEDICINAL PRODUCTS AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
GB8824492A GB2211186B (en) 1987-10-20 1988-10-19 Chemical compounds
HU885344A HU201769B (en) 1987-10-20 1988-10-19 Process for producing imidazo(2,1-b)benzothiazoles and pharmaceutical compositions comprising same as active ingredient
EP88402634A EP0313458B1 (en) 1987-10-20 1988-10-19 Imidazo(2,1-b)benzothiazoles and their acid addition salts, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them
SU925010659A RU2014334C1 (en) 1987-10-20 1992-01-14 Derivatives of imidazo(1,2-b)benzothiazole as antagonists of benzodiazepines
GR930400671T GR3009703T3 (en) 1987-10-20 1993-11-11

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878724566A GB8724566D0 (en) 1987-10-20 1987-10-20 Chemical compounds

Publications (1)

Publication Number Publication Date
GB8724566D0 true GB8724566D0 (en) 1987-11-25

Family

ID=10625613

Family Applications (2)

Application Number Title Priority Date Filing Date
GB878724566A Pending GB8724566D0 (en) 1987-10-20 1987-10-20 Chemical compounds
GB8824492A Expired - Lifetime GB2211186B (en) 1987-10-20 1988-10-19 Chemical compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB8824492A Expired - Lifetime GB2211186B (en) 1987-10-20 1988-10-19 Chemical compounds

Country Status (16)

Country Link
US (1) US4895863A (en)
EP (1) EP0313458B1 (en)
JP (1) JPH01193274A (en)
AT (1) ATE92928T1 (en)
AU (1) AU613413B2 (en)
CA (1) CA1331991C (en)
DE (1) DE3883140T2 (en)
DK (1) DK170024B1 (en)
ES (1) ES2059552T3 (en)
GB (2) GB8724566D0 (en)
GR (1) GR3009703T3 (en)
HU (1) HU201769B (en)
MX (1) MX173422B (en)
PT (1) PT88795B (en)
RU (1) RU2014334C1 (en)
ZA (1) ZA887433B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8908846D0 (en) * 1989-04-19 1989-06-07 Roussel Lab Ltd Chemical compounds
GB8908845D0 (en) * 1989-04-19 1989-06-07 Roussel Lab Ltd Chemical compounds
FR2679136A1 (en) * 1991-07-19 1993-01-22 Synthelabo Medicaments and pharmaceutical compositions based on imidazo[2,1-b]benzothiazol-3-acetamide derivatives
FR2679231B1 (en) * 1991-07-19 1994-01-14 Synthelabo IMIDAZO [2,1-B] BENZOTHIAZOLE-3-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION, IN THERAPEUTICS.
FR2679232B1 (en) * 1991-07-19 1994-01-14 Synthelabo ALPHA-HYDROXYIMIDAZO [2,1-B] BENZOTHIAZOLE-3-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2679233B1 (en) * 1991-07-19 1993-10-15 Synthelabo IMIDAZO [2,1-B] BENZOTHIAZOLE-3-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
EP0524055A1 (en) * 1991-07-19 1993-01-20 Synthelabo Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use
FR2699920B1 (en) * 1992-12-24 1995-02-10 Synthelabo Imidazo [2,1-b] benzothiazole-3-acetamide derivatives, their preparation and their therapeutic use.
FR2699921B1 (en) * 1992-12-30 1995-02-10 Synthelabo 2- (Thien-2-yl) imidazo [2,1-b] benzothiazole-3-acetic acid derivatives, their preparation and their therapeutic use.
DE59707350D1 (en) * 1996-04-04 2002-07-04 Rolic Ag Zug Imidazothiazole derivatives as a component of liquid-crystalline mixtures
DE10004572A1 (en) 2000-02-02 2001-08-09 Boehringer Ingelheim Pharma New positive allosteric AMPA receptor modulators (PAARM), processes for their production and their use as medicines
AR039774A1 (en) 2002-05-01 2005-03-02 Wyeth Corp 6-BICYCLE RENTAL-PENEMS AS BETA-LACTAMASAS INHIBITORS
AR039475A1 (en) 2002-05-01 2005-02-23 Wyeth Corp 6-ALQUILIDEN-PENEMS TRICICLICOS AS BETA-LACTAMASA INHIBITORS
GT200600380A (en) * 2005-08-24 2007-03-29 BETA-LACTAMASA INHIBITORS PREPARATION PROCESS
TWI648282B (en) 2014-03-27 2019-01-21 印度商托仁特生技有限公司 New fusion imidazole benzothiazole compound

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH621126A5 (en) * 1974-02-07 1981-01-15 Plantex Ltd
US4464384A (en) * 1981-12-23 1984-08-07 Yamanouchi Pharmaceutical Co., Ltd. 2-Phenylimidazo[2,1-b]benzothiazole compounds, salts thereof, process of producing them, and pharmaceutical compositions containing them
US4721721A (en) * 1984-12-18 1988-01-26 Rorer Pharmaceutical Corporation 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
IL78834A (en) * 1985-05-23 1992-07-15 Smithkline Beckman Corp 2,3-dihydro-5-(1,4-dihydropyridin-4-yl)-6-phenylimidazo(2,1-b)thiazoles and 6,7-dihydro-3-(1,4-dihydropyridin-4-yl)-2-phenyl-5h-imidazo(2,1-b)(1,3)thiazines and their use as intermediates in a process for preparing the corresponding pyridyl-substituted imidazo(2,1-b)thiazoles and 5h-imidazo(2,1-b)(1,3)thiazines
ZW24186A1 (en) * 1985-12-12 1987-07-08 Smithkline Beckman Corp Inhibition of the 5-lipoxygenase pathway

Also Published As

Publication number Publication date
DK579688A (en) 1989-04-21
DK170024B1 (en) 1995-05-01
AU2397888A (en) 1989-04-20
RU2014334C1 (en) 1994-06-15
HU201769B (en) 1990-12-28
DE3883140T2 (en) 1994-01-13
ES2059552T3 (en) 1994-11-16
HUT50836A (en) 1990-03-28
MX13455A (en) 1993-10-01
GB8824492D0 (en) 1988-11-23
ATE92928T1 (en) 1993-08-15
US4895863A (en) 1990-01-23
GB2211186A (en) 1989-06-28
EP0313458B1 (en) 1993-08-11
ZA887433B (en) 1990-01-31
CA1331991C (en) 1994-09-13
JPH01193274A (en) 1989-08-03
AU613413B2 (en) 1991-08-01
EP0313458A2 (en) 1989-04-26
PT88795B (en) 1993-01-29
MX173422B (en) 1994-03-03
DE3883140D1 (en) 1993-09-16
DK579688D0 (en) 1988-10-18
GB2211186B (en) 1991-07-31
GR3009703T3 (en) 1994-02-28
EP0313458A3 (en) 1990-10-31

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