NO960441L - Benzopyraner og farmasöytiske forbindelser inneholdende dem - Google Patents
Benzopyraner og farmasöytiske forbindelser inneholdende demInfo
- Publication number
- NO960441L NO960441L NO960441A NO960441A NO960441L NO 960441 L NO960441 L NO 960441L NO 960441 A NO960441 A NO 960441A NO 960441 A NO960441 A NO 960441A NO 960441 L NO960441 L NO 960441L
- Authority
- NO
- Norway
- Prior art keywords
- benzopyrans
- disease
- compounds containing
- compounds
- pharmaceutical compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 150000001562 benzopyrans Chemical class 0.000 title 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 208000012258 Diverticular disease Diseases 0.000 abstract 1
- 206010013554 Diverticulum Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010030136 Oesophageal achalasia Diseases 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Foreliggende oppfinnelse vedrører forbindelser med. formel (I) og de farmasøytisk akseptable salter derav, hvor X betyr 0, S eller NH; R og Rhver uavhengig utvelges fra H og C-C-alkyl, eller sammen betyr C-C-alkylen; RJ betyr H eller C^-C^-alkyl; R(a) betyr en 6-leddet heterocyklisk ring inneholdende 1 eller 2 N-heteroatomer, som er bundet til X med et ringkarbon-. atom, valgfritt kan være benzkondensert og valgfritt kan være substituert, (b) når X betyr NH, betyr en gruppe med formel (i) eller (c) når X betyr NH, betyr en gruppe med formel (j); og Rbetyr fenyl som er substituert med en hydroksygruppe og valgfritt kan være ytterligere substituert med 1 eller 2 substituenter; sammen med sammensetninger inneholdende slike forbin-deiser, anvendelse av, fremgangsmåter ved fremstilling. av og mellomprodukter anvendt ved fremstilling av,. slike forbindelser.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939316111A GB9316111D0 (en) | 1993-08-04 | 1993-08-04 | Benzopyrans |
PCT/EP1994/002387 WO1995004730A1 (en) | 1993-08-04 | 1994-07-18 | Benzopyrans and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
NO960441L true NO960441L (no) | 1996-02-02 |
NO960441D0 NO960441D0 (no) | 1996-02-02 |
Family
ID=10739921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO960441A NO960441D0 (no) | 1993-08-04 | 1996-02-02 | Benzopyraner og farmasöytiske forbindelser inneholdende dem |
Country Status (28)
Country | Link |
---|---|
US (2) | US5912244A (no) |
EP (1) | EP0712398B1 (no) |
JP (1) | JP2871098B2 (no) |
KR (1) | KR0175532B1 (no) |
CN (1) | CN1128536A (no) |
AT (1) | ATE152716T1 (no) |
AU (1) | AU684817B2 (no) |
CA (1) | CA2168563C (no) |
CO (1) | CO4230234A1 (no) |
CZ (1) | CZ281853B6 (no) |
DE (1) | DE69403084T2 (no) |
DK (1) | DK0712398T3 (no) |
EC (1) | ECSP941140A (no) |
EG (1) | EG20525A (no) |
ES (1) | ES2102870T3 (no) |
FI (1) | FI960487A0 (no) |
GB (1) | GB9316111D0 (no) |
GR (1) | GR3023521T3 (no) |
HU (1) | HUT75120A (no) |
IL (1) | IL110488A (no) |
NO (1) | NO960441D0 (no) |
NZ (1) | NZ271344A (no) |
PE (1) | PE56894A1 (no) |
PL (1) | PL312788A1 (no) |
SG (1) | SG42817A1 (no) |
TW (1) | TW333532B (no) |
WO (1) | WO1995004730A1 (no) |
ZA (1) | ZA945774B (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5573758A (en) * | 1995-04-28 | 1996-11-12 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers |
US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
SK167798A3 (en) * | 1996-06-07 | 2000-02-14 | Procter & Gamble | Dihydrobenzopyran and related compounds useful as anti-inflammatory agents |
US6333352B1 (en) * | 2000-04-05 | 2001-12-25 | Mimicking Man Manually, Inc. | Method of treating benign positional vertigo |
DK1381590T3 (da) * | 2001-04-16 | 2007-10-22 | Schering Corp | 3,4-disubstituerede cyclobuten-1,2-dioner som CXC-kemokinreceptorligander |
MXPA04003087A (es) * | 2001-10-04 | 2004-09-06 | Wyeth Corp | Derivados de cromano como ligados de 5-hidroxitriptamina-6. |
AU2003274569B2 (en) * | 2002-11-12 | 2008-07-31 | Warner-Lambert Company Llc | Method of stimulating hair growth using benzopyrans |
CA2555741C (en) * | 2004-02-12 | 2010-03-23 | Warner-Lambert Company Llc | Method of stimulating hair growth |
US20090110892A1 (en) * | 2004-06-30 | 2009-04-30 | General Electric Company | System and method for making a graded barrier coating |
JP2008506682A (ja) * | 2004-07-16 | 2008-03-06 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 発毛促進剤 |
AU2005266086B2 (en) * | 2004-07-19 | 2010-02-18 | Warner-Lambert Company Llc | Formulation for stimulating hair growth |
CA2591810A1 (en) * | 2004-12-21 | 2006-06-29 | F.Hoffmann-La Roche Ag | Chroman derivatives and uses thereof in the treatment of cns disorders |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3835011A1 (de) * | 1988-10-14 | 1990-04-19 | Merck Patent Gmbh | Chromanderivate |
DE3881714D1 (de) * | 1987-02-04 | 1993-07-22 | Hoechst Ag | Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen. |
DE3703227A1 (de) * | 1987-02-04 | 1988-08-18 | Hoechst Ag | Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
DE3811017A1 (de) * | 1988-03-31 | 1989-10-19 | Hoechst Ag | Ungesaettigte n-benzopyranyllactame |
AU628331B2 (en) * | 1988-05-06 | 1992-09-17 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
EP0346724A1 (de) * | 1988-06-16 | 1989-12-20 | MERCK PATENT GmbH | Chromanderivate |
DE3824446A1 (de) * | 1988-07-19 | 1990-01-25 | Hoechst Ag | Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege |
DE3827532A1 (de) * | 1988-08-13 | 1990-03-01 | Hoechst Ag | 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
DE3918041A1 (de) * | 1989-06-02 | 1990-12-06 | Merck Patent Gmbh | Chromanderivate |
US5061813A (en) * | 1990-04-02 | 1991-10-29 | E. R. Squibb & Sons, Inc. | Substituted cyanoimino benzopyranes |
GB2242628A (en) * | 1990-04-06 | 1991-10-09 | Sandoz Ltd | Asthma prophylactic use of K+ channel activators |
TW244350B (no) * | 1991-12-14 | 1995-04-01 | Hoechst Ag | |
FI930148A (fi) * | 1992-01-18 | 1993-07-19 | Hoechst Ag | Foerfarande foer enantioselektiv epoxidation av i 6-staellning substituerade kromener |
-
1993
- 1993-08-04 GB GB939316111A patent/GB9316111D0/en active Pending
-
1994
- 1994-07-08 TW TW083106236A patent/TW333532B/zh active
- 1994-07-18 ES ES94924788T patent/ES2102870T3/es not_active Expired - Lifetime
- 1994-07-18 CN CN94192981A patent/CN1128536A/zh active Pending
- 1994-07-18 JP JP7506179A patent/JP2871098B2/ja not_active Expired - Fee Related
- 1994-07-18 NZ NZ271344A patent/NZ271344A/en unknown
- 1994-07-18 DK DK94924788.6T patent/DK0712398T3/da active
- 1994-07-18 CZ CZ96331A patent/CZ281853B6/cs not_active IP Right Cessation
- 1994-07-18 US US08/591,500 patent/US5912244A/en not_active Expired - Fee Related
- 1994-07-18 DE DE69403084T patent/DE69403084T2/de not_active Expired - Fee Related
- 1994-07-18 HU HU9600238A patent/HUT75120A/hu unknown
- 1994-07-18 SG SG1995002213A patent/SG42817A1/en unknown
- 1994-07-18 WO PCT/EP1994/002387 patent/WO1995004730A1/en active IP Right Grant
- 1994-07-18 EP EP94924788A patent/EP0712398B1/en not_active Expired - Lifetime
- 1994-07-18 AU AU74948/94A patent/AU684817B2/en not_active Ceased
- 1994-07-18 PL PL94312788A patent/PL312788A1/xx unknown
- 1994-07-18 CA CA002168563A patent/CA2168563C/en not_active Expired - Fee Related
- 1994-07-18 KR KR1019960700566A patent/KR0175532B1/ko not_active IP Right Cessation
- 1994-07-18 AT AT94924788T patent/ATE152716T1/de not_active IP Right Cessation
- 1994-07-25 PE PE1994247480A patent/PE56894A1/es not_active Application Discontinuation
- 1994-07-28 IL IL11048894A patent/IL110488A/xx not_active IP Right Cessation
- 1994-08-03 ZA ZA945774A patent/ZA945774B/xx unknown
- 1994-08-03 EG EG46794A patent/EG20525A/xx active
- 1994-08-04 CO CO94034292A patent/CO4230234A1/es unknown
- 1994-08-04 EC EC1994001140A patent/ECSP941140A/es unknown
-
1996
- 1996-02-02 NO NO960441A patent/NO960441D0/no not_active Application Discontinuation
- 1996-02-02 FI FI960487A patent/FI960487A0/fi unknown
-
1997
- 1997-05-23 GR GR970401169T patent/GR3023521T3/el unknown
-
1999
- 1999-04-09 US US09/288,975 patent/US6071938A/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |