IL110488A - Benzopyrans their preparation and pharmaceutical compositions containing them - Google Patents

Benzopyrans their preparation and pharmaceutical compositions containing them

Info

Publication number
IL110488A
IL110488A IL11048894A IL11048894A IL110488A IL 110488 A IL110488 A IL 110488A IL 11048894 A IL11048894 A IL 11048894A IL 11048894 A IL11048894 A IL 11048894A IL 110488 A IL110488 A IL 110488A
Authority
IL
Israel
Prior art keywords
preparation
compositions containing
benzopyrans
pharmaceutical compositions
disease
Prior art date
Application number
IL11048894A
Other languages
English (en)
Other versions
IL110488A0 (en
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of IL110488A0 publication Critical patent/IL110488A0/xx
Priority to IL12265397A priority Critical patent/IL122653A0/xx
Publication of IL110488A publication Critical patent/IL110488A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL11048894A 1993-08-04 1994-07-28 Benzopyrans their preparation and pharmaceutical compositions containing them IL110488A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL12265397A IL122653A0 (en) 1993-08-04 1997-12-18 Benzopyrans and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939316111A GB9316111D0 (en) 1993-08-04 1993-08-04 Benzopyrans

Publications (2)

Publication Number Publication Date
IL110488A0 IL110488A0 (en) 1994-10-21
IL110488A true IL110488A (en) 1999-08-17

Family

ID=10739921

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11048894A IL110488A (en) 1993-08-04 1994-07-28 Benzopyrans their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (2) US5912244A (no)
EP (1) EP0712398B1 (no)
JP (1) JP2871098B2 (no)
KR (1) KR0175532B1 (no)
CN (1) CN1128536A (no)
AT (1) ATE152716T1 (no)
AU (1) AU684817B2 (no)
CA (1) CA2168563C (no)
CO (1) CO4230234A1 (no)
CZ (1) CZ281853B6 (no)
DE (1) DE69403084T2 (no)
DK (1) DK0712398T3 (no)
EC (1) ECSP941140A (no)
EG (1) EG20525A (no)
ES (1) ES2102870T3 (no)
FI (1) FI960487L (no)
GB (1) GB9316111D0 (no)
GR (1) GR3023521T3 (no)
HU (1) HUT75120A (no)
IL (1) IL110488A (no)
NO (1) NO960441L (no)
NZ (1) NZ271344A (no)
PE (1) PE56894A1 (no)
PL (1) PL312788A1 (no)
SG (1) SG42817A1 (no)
TW (1) TW333532B (no)
WO (1) WO1995004730A1 (no)
ZA (1) ZA945774B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573758A (en) * 1995-04-28 1996-11-12 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
AU733669B2 (en) * 1996-06-07 2001-05-24 Vanderbilt University Dihydrobenzopyran and related compounds useful as anti-inflammatory agents
US6333352B1 (en) * 2000-04-05 2001-12-25 Mimicking Man Manually, Inc. Method of treating benign positional vertigo
KR20100008794A (ko) * 2001-04-16 2010-01-26 쉐링 코포레이션 Ｃｘｃ-케모카인 수용체 리간드로서의 3,4-이치환된 사이클로부텐-1,2-디온
EP1432696A1 (en) * 2001-10-04 2004-06-30 Wyeth Chroman derivatives as 5-hydroxytryptamine-6 ligands
ATE407724T1 (de) * 2002-11-12 2008-09-15 Warner Lambert Co Methode zur stimulierung von haarwuchs auf der basis von benzopyranen
CN1917878A (zh) * 2004-02-12 2007-02-21 沃尼尔·朗伯有限责任公司 刺激毛发生长的方法
US20090110892A1 (en) * 2004-06-30 2009-04-30 General Electric Company System and method for making a graded barrier coating
US7655656B2 (en) * 2004-07-16 2010-02-02 Pfizer Inc. Hair growth promoting agents
CA2573412A1 (en) * 2004-07-19 2006-02-02 Warner-Lambert Company Llc Formulation for stimulating hair growth
WO2006066756A1 (en) * 2004-12-21 2006-06-29 F. Hoffmann-La Roche Ag Chroman derivatives and uses thereof in the treatment of cns disorders
CN117820211A (zh) * 2023-12-28 2024-04-05 上海毕得医药科技股份有限公司 一种4-羟基-5,6-二甲基吡啶-2(1h)-酮的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835011A1 (de) * 1988-10-14 1990-04-19 Merck Patent Gmbh Chromanderivate
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
ES2058148T3 (es) * 1987-02-04 1994-11-01 Hoechst Ag N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
DE3824446A1 (de) * 1988-07-19 1990-01-25 Hoechst Ag, 6230 Frankfurt Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege
DE3827532A1 (de) * 1988-08-13 1990-03-01 Hoechst Ag 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3918041A1 (de) * 1989-06-02 1990-12-06 Merck Patent Gmbh Chromanderivate
US5061813A (en) * 1990-04-02 1991-10-29 E. R. Squibb & Sons, Inc. Substituted cyanoimino benzopyranes
GB2242628A (en) * 1990-04-06 1991-10-09 Sandoz Ltd Asthma prophylactic use of K+ channel activators
TW244350B (no) * 1991-12-14 1995-04-01 Hoechst Ag
JPH0673061A (ja) * 1992-01-18 1994-03-15 Hoechst Ag ６−置換クロメン類のエナンチオ選択的エポキシ化方法

Also Published As

Publication number Publication date
EP0712398B1 (en) 1997-05-07
JPH08508042A (ja) 1996-08-27
US6071938A (en) 2000-06-06
CZ33196A3 (en) 1996-05-15
NO960441D0 (no) 1996-02-02
PL312788A1 (en) 1996-05-13
JP2871098B2 (ja) 1999-03-17
CO4230234A1 (es) 1995-10-19
NZ271344A (en) 1997-10-24
DE69403084D1 (de) 1997-06-12
EG20525A (en) 1999-06-30
FI960487A7 (fi) 1996-02-02
PE56894A1 (es) 1995-02-07
AU684817B2 (en) 1998-01-08
ES2102870T3 (es) 1997-08-01
WO1995004730A1 (en) 1995-02-16
FI960487A0 (fi) 1996-02-02
ATE152716T1 (de) 1997-05-15
DK0712398T3 (da) 1997-10-27
ECSP941140A (es) 1995-01-16
DE69403084T2 (de) 1997-08-14
GB9316111D0 (en) 1993-09-22
KR0175532B1 (ko) 1999-02-18
FI960487L (fi) 1996-02-02
SG42817A1 (en) 1997-10-17
CN1128536A (zh) 1996-08-07
TW333532B (en) 1998-06-11
CA2168563C (en) 1999-09-07
CZ281853B6 (cs) 1997-02-12
CA2168563A1 (en) 1995-02-16
GR3023521T3 (en) 1997-08-29
AU7494894A (en) 1995-02-28
US5912244A (en) 1999-06-15
HUT75120A (en) 1997-04-28
IL110488A0 (en) 1994-10-21
EP0712398A1 (en) 1996-05-22
ZA945774B (en) 1996-02-05
NO960441L (no) 1996-02-02

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Legal Events

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FF Patent granted
RH Patent void