ES2058148T3 - N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos. - Google Patents
N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.Info
- Publication number
- ES2058148T3 ES2058148T3 ES88101344T ES88101344T ES2058148T3 ES 2058148 T3 ES2058148 T3 ES 2058148T3 ES 88101344 T ES88101344 T ES 88101344T ES 88101344 T ES88101344 T ES 88101344T ES 2058148 T3 ES2058148 T3 ES 2058148T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- well
- pharmaceutical preparations
- substituted
- benzopyranil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE DESCRIBEN N-BENZOPIRANILLACTAMA DE LA FORMULA (I), EN LA QUE R1 ES CN, NO2, SOU-AR; DONDE U=1 O 2, AR ES UN SISTEMA AROMATICO O HETEROAROMATICO, QUE ES SUSTIUIDO O NO SUSTITUIDO Y P ES 1 O 2, R2 ES H, OH, (C1-C2)-ALCOXI; (C1-C2)-ALQUILO, HALOGENO O BR5R6, DONDE R5 Y R6 SON IGUALES O DIFERENTES Y SON H, (C1-C2) ALQUILO O (C1-C3)-ALQUILCARBONILO, R3 Y R4 SON IGUALES O DISTINTOS SON ALQUILO CON 1 A 4 ATOMOS DE CARBONO, LOS SIGNIFICADOS DE R1 Y R2 CITADOS ARRIBA TAMBIEN PUEDEN SER ALTERADOS, X ES UNA CADENA (CH2)M, QUE ESTA SUSTITUIDA POR AL MENOS, 1 Y COMO MAXIMO 2 M-1 GRUPOS (C1-C2)-ALQUILO, ASI COMO POR UN HETEROATOMO Y EN EL SIGNIFICADO DE O, NR7, S PUEDE SER INTERRUMPIDO Y SIGNIFICA R7H O (C1-C4)-ALQUILO Y M ES 2, 3 O 4. TIENEN ACTIVIDAD DEPRESORA DELAPRESION SANGUINEA Y/O ACTIVIDAD RELAJADORA DEL URETER. SE DESCRIBE TAMBIEN SU OBTENCION Y S APLICACION; TAMBIEN SE DESCRIBEN PREPARADOS FARMACEUTICOS CON ESTA BASE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873703229 DE3703229A1 (de) | 1987-02-04 | 1987-02-04 | Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
DE19873724876 DE3724876A1 (de) | 1987-07-28 | 1987-07-28 | Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2058148T3 true ES2058148T3 (es) | 1994-11-01 |
Family
ID=25852153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88101344T Expired - Lifetime ES2058148T3 (es) | 1987-02-04 | 1988-01-30 | N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0277611B1 (es) |
KR (1) | KR880009957A (es) |
AU (1) | AU604089B2 (es) |
DE (1) | DE3881714D1 (es) |
DK (1) | DK167440B1 (es) |
ES (1) | ES2058148T3 (es) |
FI (1) | FI92064C (es) |
HU (1) | HU207729B (es) |
IE (1) | IE60932B1 (es) |
IL (1) | IL85289A (es) |
NO (1) | NO169964C (es) |
NZ (1) | NZ223384A (es) |
PH (1) | PH24836A (es) |
PT (1) | PT86691B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3703227A1 (de) * | 1987-02-04 | 1988-08-18 | Hoechst Ag | Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
GB8800199D0 (en) * | 1988-01-06 | 1988-02-10 | Beecham Group Plc | Pharmaceutical preparation |
DE3824446A1 (de) * | 1988-07-19 | 1990-01-25 | Hoechst Ag | Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege |
DE3827532A1 (de) * | 1988-08-13 | 1990-03-01 | Hoechst Ag | 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
FR2637896B1 (fr) * | 1988-10-17 | 1990-11-30 | Adir | Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant |
DE3901720A1 (de) * | 1989-01-21 | 1990-07-26 | Hoechst Ag | Substituierte benzo(b)pyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
US5104890A (en) * | 1989-03-28 | 1992-04-14 | Fujisawa Pharmaceutical Company, Ltd. | Benzopyran derivatives and processes for preparation thereof |
IE63935B1 (en) * | 1989-06-27 | 1995-06-28 | Chem Pharm Forsch Gmbh | Novel thienopyran derivatives a process for their preparation and their use |
GB8924373D0 (en) * | 1989-10-30 | 1989-12-20 | Beecham Group Plc | Novel compounds |
AU651105B2 (en) * | 1990-06-18 | 1994-07-14 | E.R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
HUT72741A (en) * | 1992-12-19 | 1996-05-28 | Alkaloida Vegyeszeti Gyar | Method for producing benzopyrane derivatives and pharmaceutical compositions containing them |
GB9316111D0 (en) * | 1993-08-04 | 1993-09-22 | Pfizer Ltd | Benzopyrans |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0076075B1 (en) * | 1981-09-25 | 1986-11-20 | Beecham Group Plc | Pharmaceutically active benzopyran compounds |
EP0107423B1 (en) * | 1982-10-19 | 1986-07-23 | Beecham Group Plc | Novel chromans and chromenes |
GB8308064D0 (en) * | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
GB8308062D0 (en) * | 1983-03-24 | 1983-05-05 | Beecham Group Plc | Active compounds |
GB8419516D0 (en) * | 1984-07-31 | 1984-09-05 | Beecham Group Plc | Treatment |
DE3726261A1 (de) * | 1986-12-23 | 1988-07-07 | Merck Patent Gmbh | Chromanderivate |
DE3703227A1 (de) * | 1987-02-04 | 1988-08-18 | Hoechst Ag | Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
-
1988
- 1988-01-30 EP EP88101344A patent/EP0277611B1/de not_active Expired - Lifetime
- 1988-01-30 ES ES88101344T patent/ES2058148T3/es not_active Expired - Lifetime
- 1988-01-30 DE DE8888101344T patent/DE3881714D1/de not_active Expired - Fee Related
- 1988-02-02 FI FI880468A patent/FI92064C/fi not_active IP Right Cessation
- 1988-02-02 PH PH36449A patent/PH24836A/en unknown
- 1988-02-02 IL IL8528988A patent/IL85289A/en not_active IP Right Cessation
- 1988-02-02 NZ NZ223384A patent/NZ223384A/xx unknown
- 1988-02-02 HU HU88450A patent/HU207729B/hu not_active IP Right Cessation
- 1988-02-03 NO NO880474A patent/NO169964C/no unknown
- 1988-02-03 DK DK055188A patent/DK167440B1/da not_active IP Right Cessation
- 1988-02-03 KR KR1019880000967A patent/KR880009957A/ko not_active Application Discontinuation
- 1988-02-03 AU AU11227/88A patent/AU604089B2/en not_active Ceased
- 1988-02-03 IE IE29588A patent/IE60932B1/en not_active IP Right Cessation
- 1988-02-03 PT PT86691A patent/PT86691B/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PH24836A (en) | 1990-10-30 |
NZ223384A (en) | 1989-11-28 |
FI880468A0 (fi) | 1988-02-02 |
FI880468A (fi) | 1988-08-05 |
PT86691B (pt) | 1992-04-30 |
DK167440B1 (da) | 1993-11-01 |
PT86691A (pt) | 1988-03-01 |
FI92064B (fi) | 1994-06-15 |
FI92064C (fi) | 1994-09-26 |
EP0277611A2 (de) | 1988-08-10 |
AU1122788A (en) | 1988-09-08 |
NO169964C (no) | 1992-08-26 |
KR880009957A (ko) | 1988-10-06 |
HU207729B (en) | 1993-05-28 |
EP0277611B1 (de) | 1993-06-16 |
NO880474D0 (no) | 1988-02-03 |
NO880474L (no) | 1988-08-05 |
AU604089B2 (en) | 1990-12-06 |
IE880295L (en) | 1988-08-04 |
EP0277611A3 (en) | 1990-04-25 |
IL85289A0 (en) | 1988-07-31 |
DK55188D0 (da) | 1988-02-03 |
IE60932B1 (en) | 1994-09-07 |
DE3881714D1 (de) | 1993-07-22 |
IL85289A (en) | 1994-04-12 |
HUT50165A (en) | 1989-12-28 |
NO169964B (no) | 1992-05-18 |
DK55188A (da) | 1988-08-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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