DE69403084D1 - Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen - Google Patents

Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen

Info

Publication number
DE69403084D1
DE69403084D1 DE69403084T DE69403084T DE69403084D1 DE 69403084 D1 DE69403084 D1 DE 69403084D1 DE 69403084 T DE69403084 T DE 69403084T DE 69403084 T DE69403084 T DE 69403084T DE 69403084 D1 DE69403084 D1 DE 69403084D1
Authority
DE
Germany
Prior art keywords
compositions containing
benzopyrans
pharmaceutical compositions
disease
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69403084T
Other languages
English (en)
Other versions
DE69403084T2 (de
Inventor
Alexandra Mackenzie
Sandra MONAGHAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ireland Pharmaceuticals
Original Assignee
Pfizer Research and Development Co NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Research and Development Co NV SA filed Critical Pfizer Research and Development Co NV SA
Application granted granted Critical
Publication of DE69403084D1 publication Critical patent/DE69403084D1/de
Publication of DE69403084T2 publication Critical patent/DE69403084T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69403084T 1993-08-04 1994-07-18 Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen Expired - Fee Related DE69403084T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939316111A GB9316111D0 (en) 1993-08-04 1993-08-04 Benzopyrans
PCT/EP1994/002387 WO1995004730A1 (en) 1993-08-04 1994-07-18 Benzopyrans and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69403084D1 true DE69403084D1 (de) 1997-06-12
DE69403084T2 DE69403084T2 (de) 1997-08-14

Family

ID=10739921

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69403084T Expired - Fee Related DE69403084T2 (de) 1993-08-04 1994-07-18 Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen

Country Status (28)

Country Link
US (2) US5912244A (de)
EP (1) EP0712398B1 (de)
JP (1) JP2871098B2 (de)
KR (1) KR0175532B1 (de)
CN (1) CN1128536A (de)
AT (1) ATE152716T1 (de)
AU (1) AU684817B2 (de)
CA (1) CA2168563C (de)
CO (1) CO4230234A1 (de)
CZ (1) CZ281853B6 (de)
DE (1) DE69403084T2 (de)
DK (1) DK0712398T3 (de)
EC (1) ECSP941140A (de)
EG (1) EG20525A (de)
ES (1) ES2102870T3 (de)
FI (1) FI960487A0 (de)
GB (1) GB9316111D0 (de)
GR (1) GR3023521T3 (de)
HU (1) HUT75120A (de)
IL (1) IL110488A (de)
NO (1) NO960441L (de)
NZ (1) NZ271344A (de)
PE (1) PE56894A1 (de)
PL (1) PL312788A1 (de)
SG (1) SG42817A1 (de)
TW (1) TW333532B (de)
WO (1) WO1995004730A1 (de)
ZA (1) ZA945774B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573758A (en) * 1995-04-28 1996-11-12 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
AU733669B2 (en) * 1996-06-07 2001-05-24 Vanderbilt University Dihydrobenzopyran and related compounds useful as anti-inflammatory agents
US6333352B1 (en) * 2000-04-05 2001-12-25 Mimicking Man Manually, Inc. Method of treating benign positional vertigo
MXPA03009441A (es) * 2001-04-16 2004-02-12 Schering Corp Ciclobuteno-1,2-dionas 3,4-disustituidas como ligandos del receptor de quimocina cxc.
JP2005505586A (ja) * 2001-10-04 2005-02-24 ワイス 5−ヒドロキシトリプタミン−6リガンドとしてのクロマン誘導体
AU2003274569B2 (en) * 2002-11-12 2008-07-31 Warner-Lambert Company Llc Method of stimulating hair growth using benzopyrans
CN1917878A (zh) * 2004-02-12 2007-02-21 沃尼尔·朗伯有限责任公司 刺激毛发生长的方法
US20090110892A1 (en) * 2004-06-30 2009-04-30 General Electric Company System and method for making a graded barrier coating
JP2008506682A (ja) * 2004-07-16 2008-03-06 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 発毛促進剤
AU2005266086B2 (en) * 2004-07-19 2010-02-18 Warner-Lambert Company Llc Formulation for stimulating hair growth
CN101119989B (zh) * 2004-12-21 2010-06-09 弗·哈夫曼-拉罗切有限公司 色满衍生物及其在治疗cns疾病中的用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835011A1 (de) * 1988-10-14 1990-04-19 Merck Patent Gmbh Chromanderivate
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
EP0277611B1 (de) * 1987-02-04 1993-06-16 Hoechst Aktiengesellschaft Alkylsubstituierte N-Benzopyranyllactame, Verfahren zu ihrer Herstellung, ihre Verwendung sowie pharmazeutische Präparate auf Basis dieser Verbindungen
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
DE3824446A1 (de) * 1988-07-19 1990-01-25 Hoechst Ag Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege
DE3827532A1 (de) * 1988-08-13 1990-03-01 Hoechst Ag 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3918041A1 (de) * 1989-06-02 1990-12-06 Merck Patent Gmbh Chromanderivate
US5061813A (en) * 1990-04-02 1991-10-29 E. R. Squibb & Sons, Inc. Substituted cyanoimino benzopyranes
GB2242628A (en) * 1990-04-06 1991-10-09 Sandoz Ltd Asthma prophylactic use of K+ channel activators
TW244350B (de) * 1991-12-14 1995-04-01 Hoechst Ag
JPH0673061A (ja) * 1992-01-18 1994-03-15 Hoechst Ag 6−置換クロメン類のエナンチオ選択的エポキシ化方法

Also Published As

Publication number Publication date
DE69403084T2 (de) 1997-08-14
WO1995004730A1 (en) 1995-02-16
CO4230234A1 (es) 1995-10-19
KR0175532B1 (ko) 1999-02-18
JP2871098B2 (ja) 1999-03-17
ECSP941140A (es) 1995-01-16
FI960487A (fi) 1996-02-02
AU684817B2 (en) 1998-01-08
CN1128536A (zh) 1996-08-07
NO960441D0 (no) 1996-02-02
EP0712398A1 (de) 1996-05-22
ES2102870T3 (es) 1997-08-01
CZ281853B6 (cs) 1997-02-12
HUT75120A (en) 1997-04-28
GB9316111D0 (en) 1993-09-22
IL110488A0 (en) 1994-10-21
CA2168563C (en) 1999-09-07
PE56894A1 (es) 1995-02-07
ATE152716T1 (de) 1997-05-15
DK0712398T3 (da) 1997-10-27
EP0712398B1 (de) 1997-05-07
FI960487A0 (fi) 1996-02-02
NO960441L (no) 1996-02-02
AU7494894A (en) 1995-02-28
CA2168563A1 (en) 1995-02-16
US5912244A (en) 1999-06-15
TW333532B (en) 1998-06-11
US6071938A (en) 2000-06-06
PL312788A1 (en) 1996-05-13
SG42817A1 (en) 1997-10-17
ZA945774B (en) 1996-02-05
EG20525A (en) 1999-06-30
CZ33196A3 (en) 1996-05-15
IL110488A (en) 1999-08-17
JPH08508042A (ja) 1996-08-27
NZ271344A (en) 1997-10-24
GR3023521T3 (en) 1997-08-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER IRELAND PHARMACEUTICALS, DUBLIN, IE

8339 Ceased/non-payment of the annual fee