NO974767L - Anvendelse av glianeurotrof faktor (GDNF) til behandling av hörselsforstyrrelser - Google Patents

Anvendelse av glianeurotrof faktor (GDNF) til behandling av hörselsforstyrrelser

Info

Publication number
NO974767L
NO974767L NO974767A NO974767A NO974767L NO 974767 L NO974767 L NO 974767L NO 974767 A NO974767 A NO 974767A NO 974767 A NO974767 A NO 974767A NO 974767 L NO974767 L NO 974767L
Authority
NO
Norway
Prior art keywords
gdnf
neurotrophic factor
treatment
hearing disorders
glial
Prior art date
Application number
NO974767A
Other languages
English (en)
Norwegian (no)
Other versions
NO974767D0 (no
Inventor
Ella Magal
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/606,176 external-priority patent/US5837681A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO974767D0 publication Critical patent/NO974767D0/no
Publication of NO974767L publication Critical patent/NO974767L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/185Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
NO974767A 1996-02-23 1997-10-15 Anvendelse av glianeurotrof faktor (GDNF) til behandling av hörselsforstyrrelser NO974767L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/606,176 US5837681A (en) 1996-02-23 1996-02-23 Method for treating sensorineural hearing loss using glial cell line-derived neurotrophic factor (GDNF) protein product
US08/710,219 US5929041A (en) 1996-02-23 1996-09-13 Method for preventing and treating sensorineural hearing loss and vestibular disorders using glial cell line-derived neurotrophic factor(GDNF) protein product
PCT/US1997/002677 WO1997030722A1 (en) 1996-02-23 1997-02-14 Use of glial neurotrophic factor (gdnf) for treatment of hearing disorders

Publications (2)

Publication Number Publication Date
NO974767D0 NO974767D0 (no) 1997-10-15
NO974767L true NO974767L (no) 1997-12-22

Family

ID=27085161

Family Applications (1)

Application Number Title Priority Date Filing Date
NO974767A NO974767L (no) 1996-02-23 1997-10-15 Anvendelse av glianeurotrof faktor (GDNF) til behandling av hörselsforstyrrelser

Country Status (21)

Country Link
US (1) US5929041A (de)
EP (1) EP0822829B1 (de)
JP (1) JP4028598B2 (de)
KR (1) KR100271247B1 (de)
CN (1) CN1130221C (de)
AT (1) ATE211392T1 (de)
AU (1) AU691443B2 (de)
CA (1) CA2217565C (de)
CZ (1) CZ322797A3 (de)
DE (1) DE69709458T2 (de)
DK (1) DK0822829T3 (de)
EA (1) EA199700225A1 (de)
ES (1) ES2170938T3 (de)
HU (1) HU223999B1 (de)
IL (1) IL121790A (de)
MX (1) MX9707669A (de)
NO (1) NO974767L (de)
NZ (1) NZ328918A (de)
PT (1) PT822829E (de)
SK (1) SK138697A3 (de)
WO (1) WO1997030722A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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US6184200B1 (en) * 1995-09-28 2001-02-06 Amgen Inc. Truncated glial cell line-derived neurotrophic factor
US6677135B1 (en) 1996-05-08 2004-01-13 Biogen, Inc. Ret ligand (RetL) for stimulating neutral and renal growth
AU5244998A (en) * 1996-11-15 1998-06-03 Creative Biomolecules, Inc. Morphogen-induced regeneration of sense perceptory tissues
SI1005358T1 (en) * 1997-07-30 2003-06-30 Amgen Inc. Use of a neurturin protein product for preventing and treating hearing loss
US6043221A (en) * 1997-07-30 2000-03-28 Amgen Inc. Method for preventing and treating hearing loss using a neuturin protein product
US6177434B1 (en) * 1997-12-16 2001-01-23 The United States Of America As Represented By The Secretary Of The Navy Prevention or reversal of sensorineural hearing loss (SNHL) through biologic mechanisms
US7236888B2 (en) * 1998-03-06 2007-06-26 The Regents Of The University Of California Method to measure the activation state of signaling pathways in cells
US6304787B1 (en) 1998-08-26 2001-10-16 Advanced Bionics Corporation Cochlear electrode array having current-focusing and tissue-treating features
US6309410B1 (en) 1998-08-26 2001-10-30 Advanced Bionics Corporation Cochlear electrode with drug delivery channel and method of making same
AU763435B2 (en) 1998-09-25 2003-07-24 Cephalon, Inc. Methods for preventing/treating damage to sensory hair cells and cochlear neurons
US7053200B1 (en) 1999-06-01 2006-05-30 Baylor College Of Medicine Compositions and methods for the therapeutic use of an atonal-associated sequence for deafness, osteoarthritis, and abnormal cell proliferation
AU781802B2 (en) * 1999-06-01 2005-06-16 Baylor College Of Medicine Compositions and methods for the therapeutic use of an atonal-associated sequence for deafness, osteoarthritis, and abnormal cell proliferation
DK1223966T3 (da) * 1999-10-29 2003-08-18 Bioph Biotech Entw Pharm Gmbh Anvendelse af GDNF til behandling af hornhindedefekter
US6551575B1 (en) 1999-12-02 2003-04-22 Neurosciences Research Foundation, Inc. Methods for identifying compounds for motion sickness, vertigo and other disorders related to balance and the perception of gravity
DE10025152A1 (de) * 2000-05-23 2001-12-06 Marlies Knipper Neurotrophin stimulierende Substanzen, insbesondere Thyroidhormon (T3) oder Schilddrüsenhormon stimulierende Substanzen, für die therapeutische Behandlung von lärm-und altersbedingter Schwerhörigkeit
AUPR148400A0 (en) * 2000-11-14 2000-12-07 Cochlear Limited Apparatus for delivery of pharmaceuticals to the cochlea
US9089450B2 (en) * 2000-11-14 2015-07-28 Cochlear Limited Implantatable component having an accessible lumen and a drug release capsule for introduction into same
US20030191064A1 (en) * 2001-01-23 2003-10-09 Kopke Richard D. Methods for preventing and treating loss of balance function due to oxidative stress
US20030050273A1 (en) * 2001-08-29 2003-03-13 Keiya Ozawa Compositions and methods for treating neurodegenerative diseases
AUPR879201A0 (en) * 2001-11-09 2001-12-06 Cochlear Limited Subthreshold stimulation of a cochlea
AUPS081502A0 (en) * 2002-02-28 2002-03-21 Cochlear Limited Connector for drug delivery system
DE60332748D1 (de) * 2002-10-02 2010-07-08 Anges Mg Inc Arzneimittel gegen hörfunktionsstörungen
US8515560B2 (en) * 2002-11-29 2013-08-20 Cochlear Limited Medical implant drug delivery device
US20040166091A1 (en) * 2003-02-24 2004-08-26 Genvec, Inc. Materials and methods for treating disorders of the ear
US8309057B2 (en) * 2005-06-10 2012-11-13 The Invention Science Fund I, Llc Methods for elevating neurotrophic agents
US8133215B2 (en) * 2007-08-13 2012-03-13 Cochlear Limited Independently-manufactured drug delivery module and corresponding receptacle in an implantable medical device
US8190271B2 (en) * 2007-08-29 2012-05-29 Advanced Bionics, Llc Minimizing trauma during and after insertion of a cochlear lead
US8271101B2 (en) * 2007-08-29 2012-09-18 Advanced Bionics Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
CA2721927C (en) 2008-04-21 2014-01-28 Otonomy, Inc. Auris formulations for treating otic diseases and conditions
US8617097B2 (en) 2010-05-24 2013-12-31 Cochlear Limited Drug-delivery accessory for an implantable medical device
US8920855B1 (en) 2012-10-30 2014-12-30 Setem Hemth, Inc Methods of topically treating tinnitus and related disorders
EP2968462B1 (de) 2013-03-15 2020-12-23 The Jackson Laboratory Verfahren zur förderung von wundheilung und haarwachstum
US10265380B2 (en) 2014-03-05 2019-04-23 Amarantus Bioscience Holdings, Inc. Method of administering MANF for the protection of sensory cells
TWI710635B (zh) 2014-10-09 2020-11-21 美商珍維克公司 編碼人類無調同源物-1(hath1)之腺病毒載體
AU2017259966A1 (en) * 2016-05-03 2018-11-22 The Scripps Research Institute TrkB agonist antibodies for treating neurodegenerative disorders
US11912750B2 (en) 2016-11-10 2024-02-27 Keros Therapeutics, Inc. GDNF fusion polypeptides and methods of use thereof
EP3406259A1 (de) * 2017-05-24 2018-11-28 Dompé farmaceutici S.p.A. Neurotrophine zur verwendung bei der behandlung von hörverlust
CN115869389A (zh) * 2018-01-09 2023-03-31 奥德纳米有限公司 生长因子耳用制剂
CN112920998B (zh) * 2021-02-05 2022-06-14 复旦大学附属眼耳鼻喉科医院 一种成年鼠耳蜗体培养体系的建立方法及其应用

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US5106627A (en) * 1987-11-17 1992-04-21 Brown University Research Foundation Neurological therapy devices
CA2006596C (en) * 1988-12-22 2000-09-05 Rika Ishikawa Chemically-modified g-csf
WO1991010470A1 (en) * 1990-01-08 1991-07-25 Brown University Research Foundation Devices and methods for enhanced delivery of active factors
KR100242093B1 (ko) * 1991-09-20 2000-02-01 그레고리 아보트 신경교 유도 신경 영양성 인자
EP0802800B1 (de) * 1993-08-12 2002-06-12 Neurotech S.A. Biokompatible immunoisolatorische Kapseln, die genetisch veränderte Zellen enthalten
FR2717824B1 (fr) * 1994-03-25 1996-04-26 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
US5658785A (en) * 1994-06-06 1997-08-19 Children's Hospital, Inc. Adeno-associated virus materials and methods

Also Published As

Publication number Publication date
IL121790A (en) 2002-08-14
MX9707669A (es) 1997-11-29
AU2277997A (en) 1997-09-10
CA2217565C (en) 2002-04-16
SK138697A3 (en) 1998-02-04
AU691443B2 (en) 1998-05-14
DE69709458D1 (de) 2002-02-07
CA2217565A1 (en) 1997-08-28
DK0822829T3 (da) 2002-04-02
JPH11504351A (ja) 1999-04-20
KR19980703748A (ko) 1998-12-05
EA199700225A1 (ru) 1998-04-30
DE69709458T2 (de) 2002-08-29
IL121790A0 (en) 1998-02-22
NO974767D0 (no) 1997-10-15
ES2170938T3 (es) 2002-08-16
ATE211392T1 (de) 2002-01-15
CN1181704A (zh) 1998-05-13
KR100271247B1 (ko) 2000-11-01
WO1997030722A1 (en) 1997-08-28
NZ328918A (en) 1999-08-30
HUP9901758A2 (hu) 1999-08-30
CZ322797A3 (cs) 1998-01-14
EP0822829A1 (de) 1998-02-11
US5929041A (en) 1999-07-27
PT822829E (pt) 2002-06-28
HUP9901758A3 (en) 2001-10-29
EP0822829B1 (de) 2002-01-02
JP4028598B2 (ja) 2007-12-26
HU223999B1 (hu) 2005-04-28
CN1130221C (zh) 2003-12-10

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