NO972222L - Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midler - Google Patents
Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midlerInfo
- Publication number
- NO972222L NO972222L NO972222A NO972222A NO972222L NO 972222 L NO972222 L NO 972222L NO 972222 A NO972222 A NO 972222A NO 972222 A NO972222 A NO 972222A NO 972222 L NO972222 L NO 972222L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- date
- spp
- mycobacterium
- oxazine
- Prior art date
Links
- BCHZICNRHXRCHY-UHFFFAOYSA-N 2h-oxazine Chemical compound N1OC=CC=C1 BCHZICNRHXRCHY-UHFFFAOYSA-N 0.000 title abstract 2
- AGIJRRREJXSQJR-UHFFFAOYSA-N 2h-thiazine Chemical compound N1SC=CC=C1 AGIJRRREJXSQJR-UHFFFAOYSA-N 0.000 title abstract 2
- 125000002619 bicyclic group Chemical group 0.000 title abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241001148536 Bacteroides sp. Species 0.000 abstract 1
- 241001112696 Clostridia Species 0.000 abstract 1
- 241000186359 Mycobacterium Species 0.000 abstract 1
- 241000186367 Mycobacterium avium Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 241000295644 Staphylococcaceae Species 0.000 abstract 1
- 241001148470 aerobic bacillus Species 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33997994A | 1994-11-15 | 1994-11-15 | |
| PCT/US1995/012751 WO1996015130A1 (en) | 1994-11-15 | 1995-10-31 | Bicyclic oxazine and thiazine oxazolidinone antibacterials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO972222D0 NO972222D0 (no) | 1997-05-14 |
| NO972222L true NO972222L (no) | 1997-05-14 |
Family
ID=23331388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972222A NO972222L (no) | 1994-11-15 | 1997-05-14 | Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5952324A (de) |
| EP (1) | EP0792273B1 (de) |
| JP (1) | JPH10508844A (de) |
| KR (1) | KR100392216B1 (de) |
| CN (1) | CN1046520C (de) |
| AT (1) | ATE233766T1 (de) |
| AU (1) | AU702733B2 (de) |
| BR (1) | BR9509673A (de) |
| DE (1) | DE69529838T2 (de) |
| DK (1) | DK0792273T3 (de) |
| ES (1) | ES2193201T3 (de) |
| MX (1) | MX9703543A (de) |
| NO (1) | NO972222L (de) |
| NZ (1) | NZ295528A (de) |
| PT (1) | PT792273E (de) |
| RU (1) | RU2128660C1 (de) |
| WO (1) | WO1996015130A1 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2214546T3 (es) * | 1995-09-15 | 2004-09-16 | PHARMACIA & UPJOHN COMPANY | N-oxidos de aminoariloxazolidinona. |
| ZA968661B (en) * | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
| GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| GB9702213D0 (en) * | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| DK1114819T3 (da) * | 1996-04-11 | 2008-04-14 | Pharmacia & Upjohn Co Llc | Fremgangsmåde til fremstilling af oxazolidinoner |
| GB9609919D0 (en) * | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
| KR100307211B1 (ko) * | 1997-05-24 | 2001-11-30 | 손 경 식 | 옥사졸리디논유도체,이의제조방법및그를함유한항균제조성물 |
| GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| KR100467309B1 (ko) * | 1997-09-04 | 2005-07-18 | 씨제이 주식회사 | 옥사졸리디논유도체및그의제조방법및항균제조성물 |
| KR100463111B1 (ko) * | 1997-10-30 | 2005-06-13 | 씨제이 주식회사 | 신규한옥사졸리디논유도체및제조방법및그를함유하는항균제조성물 |
| GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
| SK18362000A3 (sk) | 1998-06-05 | 2001-06-11 | Astrazeneca Ab | Oxazolidinónové deriváty, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú |
| US6413981B1 (en) * | 1999-08-12 | 2002-07-02 | Ortho-Mcneil Pharamceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| US6608081B2 (en) | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| EA005567B1 (ru) * | 1999-12-21 | 2005-04-28 | Фармация Энд Апджон Компани | Оксазолидиноны, обладающие сульфоксиминовой функциональностью |
| US6518285B2 (en) | 1999-12-21 | 2003-02-11 | Ortho Mcneil Pharmaceutical, Inc. | Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| EP1328509B1 (de) | 2000-10-17 | 2006-03-22 | Pharmacia & Upjohn Company LLC | Verfahren zur herstellung von oxazolidinonverbindungen |
| EP1385844B1 (de) * | 2001-04-07 | 2006-07-05 | Astrazeneca AB | Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika |
| GB0108793D0 (en) * | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
| DE60222645T2 (de) * | 2001-04-20 | 2008-07-17 | Pharmacia & Upjohn Co. Llc, Kalamazoo | Verfahren zur herstellung von oxazolidinonen |
| TW200302095A (en) * | 2002-01-25 | 2003-08-01 | Upjohn Co | Oxazolidinone cotherapy |
| AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| JP2005527575A (ja) * | 2002-03-29 | 2005-09-15 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 糖尿病性足病変感染を治療するためのオキサゾリジノンの非経口、静脈内および経口投与 |
| ATE321760T1 (de) * | 2002-08-12 | 2006-04-15 | Pharmacia & Upjohn Co Llc | N-aryl-2-oxazolidinone und deren derivate |
| AR042086A1 (es) * | 2002-11-21 | 2005-06-08 | Upjohn Co | N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos |
| EP1594865A2 (de) * | 2003-02-07 | 2005-11-16 | Warner-Lambert Company LLC | Antibakterielle mittel |
| JP2006516989A (ja) * | 2003-02-07 | 2006-07-13 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体 |
| US20040204463A1 (en) * | 2003-04-01 | 2004-10-14 | Harris Christina Renee | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| US20070004679A1 (en) * | 2004-05-17 | 2007-01-04 | Nathalie Schlienger | Androgen receptor modulators and methods of treating disease using the same |
| AU2005247405A1 (en) * | 2004-05-17 | 2005-12-08 | Acadia Pharmaceuticals Inc. | Androgen receptor modulators and method of treating disease using the same |
| US20050261278A1 (en) * | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| WO2006016220A1 (en) * | 2004-08-06 | 2006-02-16 | Pharmacia & Upjohn Company Llc | Oxindole oxazolidinones as antibacterial agents |
| EP2302078B1 (de) | 2004-11-03 | 2015-07-15 | Iris Molecular Diagnostics, Inc. | Mikrobläschen zur Konzentration mittels Affinitätstrennung |
| CA2585781A1 (en) | 2004-11-03 | 2006-12-28 | Iris Molecular Diagnostics, Inc. | Homogeneous analyte detection |
| CN101119993B (zh) * | 2005-01-10 | 2015-03-04 | 阿卡蒂亚药品公司 | 作为选择性雄激素受体调节剂的氨基苯基衍生物 |
| US20060173037A1 (en) * | 2005-01-10 | 2006-08-03 | Nathalie Schlienger | Aminophenyl derivatives as selective androgen receptor modulators |
| EP1899331B1 (de) | 2005-06-29 | 2009-11-25 | Pharmacia & Upjohn Company LLC | Homomorpholinoxazolidinone als antibakterielle mittel |
| CA2712613C (en) * | 2008-03-26 | 2017-02-28 | Global Alliance For Tb Drug Development | Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones |
| KR20180022826A (ko) | 2015-07-02 | 2018-03-06 | 얀센 사이언시즈 아일랜드 유씨 | 항균 화합물 |
| ES2897973T3 (es) * | 2015-07-17 | 2022-03-03 | The Global Alliance For Tb Drug Dev Inc | Feniloxazolidinonas sustituidas para terapia antimicrobiana |
| MX2018015656A (es) | 2016-06-16 | 2019-03-14 | Janssen Sciences Ireland Unlimited Co | Compuestos heterociclicos como antibacterianos. |
| US11224596B2 (en) | 2017-03-01 | 2022-01-18 | Janssen Sciences Ireland Unlimited Company | PZA and cytochrome bc1 inhibitor combination treatment |
| WO2020147504A1 (en) * | 2019-01-18 | 2020-07-23 | Merck Sharp & Dohme Corp. | Oxazolidinone compounds and methods of use thereof as antibacterial agents |
| WO2020234636A1 (en) | 2019-05-17 | 2020-11-26 | Cadila Healthcare Limited | Novel compounds for the treatment of mammalian infections |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801600A (en) * | 1987-10-09 | 1989-01-31 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| US4921869A (en) * | 1987-10-09 | 1990-05-01 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| CA1320730C (en) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| EP0316594B1 (de) * | 1987-10-21 | 1993-09-29 | The Du Pont Merck Pharmaceutical Company | Aminomethyl-oxo-oxazolidinyl-ethenylbenzen-Derivate, nützlich als antibakterielles Mittel |
| US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| EP0434714A1 (de) * | 1988-09-15 | 1991-07-03 | The Upjohn Company | In stellung3-substituierte 5-beta-amidomethyloxazolinden-2-on-derivate |
| EP0610265B1 (de) * | 1991-11-01 | 1996-12-27 | PHARMACIA & UPJOHN COMPANY | Substituierte aryl- und heteroaryl-phenyloxazolidinone |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| MY115155A (en) * | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| CA2174107C (en) * | 1993-11-22 | 2005-04-12 | Steven J. Brickner | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| US5668286A (en) * | 1994-03-15 | 1997-09-16 | Pharmacia & Upjohn Company | Oxazolidinone derivatives and pharmaceutical compositions containing them |
-
1995
- 1995-10-31 NZ NZ295528A patent/NZ295528A/xx unknown
- 1995-10-31 KR KR1019970703234A patent/KR100392216B1/ko not_active IP Right Cessation
- 1995-10-31 CN CN95196252A patent/CN1046520C/zh not_active Expired - Fee Related
- 1995-10-31 US US09/051,466 patent/US5952324A/en not_active Expired - Fee Related
- 1995-10-31 PT PT95938148T patent/PT792273E/pt unknown
- 1995-10-31 ES ES95938148T patent/ES2193201T3/es not_active Expired - Lifetime
- 1995-10-31 WO PCT/US1995/012751 patent/WO1996015130A1/en active IP Right Grant
- 1995-10-31 EP EP95938148A patent/EP0792273B1/de not_active Expired - Lifetime
- 1995-10-31 BR BR9509673A patent/BR9509673A/pt not_active Application Discontinuation
- 1995-10-31 JP JP8516040A patent/JPH10508844A/ja active Pending
- 1995-10-31 MX MX9703543A patent/MX9703543A/es not_active IP Right Cessation
- 1995-10-31 RU RU97110168A patent/RU2128660C1/ru not_active IP Right Cessation
- 1995-10-31 AU AU38890/95A patent/AU702733B2/en not_active Ceased
- 1995-10-31 AT AT95938148T patent/ATE233766T1/de not_active IP Right Cessation
- 1995-10-31 DK DK95938148T patent/DK0792273T3/da active
- 1995-10-31 DE DE69529838T patent/DE69529838T2/de not_active Expired - Fee Related
-
1997
- 1997-05-14 NO NO972222A patent/NO972222L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU702733B2 (en) | 1999-03-04 |
| WO1996015130A1 (en) | 1996-05-23 |
| DE69529838D1 (de) | 2003-04-10 |
| BR9509673A (pt) | 1997-09-30 |
| CN1163615A (zh) | 1997-10-29 |
| RU2128660C1 (ru) | 1999-04-10 |
| NO972222D0 (no) | 1997-05-14 |
| DK0792273T3 (da) | 2003-06-16 |
| AU3889095A (en) | 1996-06-06 |
| MX9703543A (es) | 1997-08-30 |
| ES2193201T3 (es) | 2003-11-01 |
| PT792273E (pt) | 2003-06-30 |
| CN1046520C (zh) | 1999-11-17 |
| KR100392216B1 (ko) | 2003-10-17 |
| JPH10508844A (ja) | 1998-09-02 |
| NZ295528A (en) | 1999-03-29 |
| ATE233766T1 (de) | 2003-03-15 |
| EP0792273B1 (de) | 2003-03-05 |
| DE69529838T2 (de) | 2003-11-13 |
| EP0792273A1 (de) | 1997-09-03 |
| US5952324A (en) | 1999-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |