NO964904L - Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikamenter inneholdende dem - Google Patents
Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikamenter inneholdende demInfo
- Publication number
- NO964904L NO964904L NO964904A NO964904A NO964904L NO 964904 L NO964904 L NO 964904L NO 964904 A NO964904 A NO 964904A NO 964904 A NO964904 A NO 964904A NO 964904 L NO964904 L NO 964904L
- Authority
- NO
- Norway
- Prior art keywords
- stands
- atoms
- alkyl
- well
- hydrogen
- Prior art date
Links
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical class OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 2
- 229940079593 drug Drugs 0.000 title 2
- KKEYFWRCBNTPAC-UHFFFAOYSA-N benzene-dicarboxylic acid Natural products OC(=O)C1=CC=C(C(O)=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 230000006378 damage Effects 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000003293 cardioprotective effect Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 239000003193 general anesthetic agent Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001960 triggered effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19543194A DE19543194A1 (de) | 1995-11-20 | 1995-11-20 | Substituierte Benzoldicarbonsäure-diguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE1996126327 DE19626327A1 (de) | 1996-07-01 | 1996-07-01 | Substituierte Benzoldicarbonsäure-diguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO964904D0 NO964904D0 (no) | 1996-11-19 |
| NO964904L true NO964904L (no) | 1997-05-21 |
Family
ID=26020503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964904A NO964904L (no) | 1995-11-20 | 1996-11-19 | Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikamenter inneholdende dem |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5731350A (cs) |
| EP (1) | EP0774457A1 (cs) |
| JP (1) | JPH09169718A (cs) |
| KR (1) | KR980009237A (cs) |
| AR (1) | AR004332A1 (cs) |
| AU (1) | AU7180396A (cs) |
| BR (1) | BR9605613A (cs) |
| CA (1) | CA2190692A1 (cs) |
| CZ (1) | CZ338396A3 (cs) |
| HR (1) | HRP960548A2 (cs) |
| HU (1) | HUP9603195A3 (cs) |
| IL (1) | IL119636A0 (cs) |
| MX (1) | MX9605675A (cs) |
| NO (1) | NO964904L (cs) |
| PL (1) | PL316439A1 (cs) |
| SK (1) | SK148896A3 (cs) |
| TR (1) | TR199600917A2 (cs) |
| TW (1) | TW349945B (cs) |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3780027A (en) * | 1970-04-29 | 1973-12-18 | Merck & Co Inc | Anthranilic acid derivatives |
| WO1989006534A1 (en) * | 1988-01-15 | 1989-07-27 | Abbott Laboratories | Aminomethyl-chroman and -thiochroman compounds |
| US5140039A (en) * | 1988-01-15 | 1992-08-18 | Abbott Laboratories | Aminomethyl-thiochroman compounds |
| US5185364A (en) * | 1988-01-15 | 1993-02-09 | Abbott Laboratories | Aminomethyl-chroman and -thiochroman compounds |
| DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| CZ284456B6 (cs) * | 1992-02-15 | 1998-12-16 | Hoechst Aktiengesellschaft | Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje |
| DE59302959D1 (de) | 1992-02-15 | 1996-07-25 | Hoechst Ag | 3,5-Substituierte Benzoylguanidine, mit antiarrythmischer Wirkung und inhibierender Wirkung auf die Proliferationen von Zellen |
| ES2108144T3 (es) * | 1992-02-15 | 1997-12-16 | Hoechst Ag | Benzoilguanidinas sustituidas en orto, procedimiento para su preparacion, su utilizacion como medicamento o agente de diagnostico, asi como medicamento que las contiene. |
| ATE144248T1 (de) * | 1992-07-01 | 1996-11-15 | Hoechst Ag | 3,4,5-substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament |
| ATE147375T1 (de) * | 1992-09-22 | 1997-01-15 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, sowie ihre verwendung als antiarrhythmika |
| DK0590455T3 (da) * | 1992-09-28 | 2001-01-22 | Hoechst Ag | Antiarrytmiske og cardioprotektive substiuerede 1(2H)-isoquinoliner, fremgangsmåde til deres fremstilling, lægemiddel indeh |
| DE59309360D1 (de) * | 1992-12-02 | 1999-03-18 | Hoechst Ag | Guanidinalkyl-1, 1-bisphosphonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| TW250479B (cs) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
| TW250477B (cs) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
| DE59306029D1 (de) * | 1992-12-16 | 1997-05-07 | Hoechst Ag | 3,5-Substituierte Aminobenzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| EP0604852A1 (de) * | 1992-12-28 | 1994-07-06 | Hoechst Aktiengesellschaft | 2,4-Substituierte 5-(N-substituierte-Sulfamoyl)-Benzoylguanidine, als Antiarrythmika, Inhibitoren der Proliferationen von Zellen, und Inhibitoren des Natrium-Protonen-Antiporters |
| EP0612723B1 (de) * | 1993-02-20 | 1997-08-27 | Hoechst Aktiengesellschaft | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament |
| DE59401361D1 (de) * | 1993-02-23 | 1997-02-06 | Hoechst Ag | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe- Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika |
| IL109570A0 (en) * | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4318658A1 (de) * | 1993-06-04 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4325822A1 (de) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| EP0639573A1 (de) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
| DE4327244A1 (de) * | 1993-08-13 | 1995-02-16 | Hoechst Ag | Harnstoffsubstituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4344550A1 (de) * | 1993-12-24 | 1995-06-29 | Hoechst Ag | Substituierte 1-Oxo-1,2-dihydro-isochinolinoyl- und 1,1-Dioxo-2H-1,2-benzothiazinoylguanidine, Verfahrenzu ihrer Herstellung, ihre Verwendung als Medikamentt oder Diagnostikum sowie sie enthaltendes Medikamen |
| TW415937B (en) * | 1994-01-25 | 2000-12-21 | Hoechst Ag | Phenyl-substituted alkylcarboxylic acid guanidides bearing perfluoroalkyl groups, process for their preparation, their use as a medicament or diagnostic, and medicament containing them |
| DE4412334A1 (de) * | 1994-04-11 | 1995-10-19 | Hoechst Ag | Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4415873A1 (de) * | 1994-05-05 | 1995-11-09 | Hoechst Ag | Substituierte bizyklische Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4422685A1 (de) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| IL114670A0 (en) * | 1994-08-05 | 1995-11-27 | Fujisawa Pharmaceutical Co | Guanidine derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4432101A1 (de) * | 1994-09-09 | 1996-03-14 | Hoechst Ag | Aminosäure-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4432106A1 (de) * | 1994-09-09 | 1996-03-14 | Hoechst Ag | Mit Heterocyclen-N-Oxid-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum, sie enthaltendes Medikament sowie Zwischenprodukte zu ihrer Herstellung |
| DE4432105A1 (de) * | 1994-09-09 | 1996-03-14 | Hoechst Ag | Fluoro-alkyl/alkenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4441880A1 (de) * | 1994-11-24 | 1996-05-30 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE59603311D1 (de) * | 1995-01-30 | 1999-11-18 | Hoechst Ag | Basisch-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-10-08 PL PL96316439A patent/PL316439A1/xx unknown
- 1996-11-07 EP EP96117821A patent/EP0774457A1/de not_active Withdrawn
- 1996-11-07 US US08/747,004 patent/US5731350A/en not_active Expired - Fee Related
- 1996-11-18 AR ARP960105231A patent/AR004332A1/es unknown
- 1996-11-18 SK SK1488-96A patent/SK148896A3/sk unknown
- 1996-11-18 TR TR96/00917A patent/TR199600917A2/xx unknown
- 1996-11-18 TW TW085114094A patent/TW349945B/zh active
- 1996-11-18 CZ CZ963383A patent/CZ338396A3/cs unknown
- 1996-11-18 AU AU71803/96A patent/AU7180396A/en not_active Abandoned
- 1996-11-18 IL IL11963696A patent/IL119636A0/xx unknown
- 1996-11-19 NO NO964904A patent/NO964904L/no unknown
- 1996-11-19 HU HU9603195A patent/HUP9603195A3/hu unknown
- 1996-11-19 CA CA002190692A patent/CA2190692A1/en not_active Abandoned
- 1996-11-19 JP JP8307830A patent/JPH09169718A/ja active Pending
- 1996-11-19 HR HR19626327.1A patent/HRP960548A2/hr not_active Application Discontinuation
- 1996-11-19 MX MX9605675A patent/MX9605675A/es unknown
- 1996-11-19 BR BR9605613A patent/BR9605613A/pt not_active Application Discontinuation
- 1996-11-20 KR KR1019960055717A patent/KR980009237A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AR004332A1 (es) | 1998-11-04 |
| SK148896A3 (en) | 1997-10-08 |
| TR199600917A2 (tr) | 1997-06-21 |
| EP0774457A1 (de) | 1997-05-21 |
| MX9605675A (es) | 1997-08-30 |
| TW349945B (en) | 1999-01-11 |
| CA2190692A1 (en) | 1997-05-21 |
| HRP960548A2 (en) | 1998-02-28 |
| HUP9603195A3 (en) | 1997-11-28 |
| HUP9603195A2 (en) | 1997-05-28 |
| KR980009237A (ko) | 1998-04-30 |
| IL119636A0 (en) | 1997-02-18 |
| AU7180396A (en) | 1997-05-29 |
| JPH09169718A (ja) | 1997-06-30 |
| NO964904D0 (no) | 1996-11-19 |
| PL316439A1 (en) | 1997-05-26 |
| US5731350A (en) | 1998-03-24 |
| HU9603195D0 (en) | 1997-01-28 |
| CZ338396A3 (cs) | 1998-05-13 |
| BR9605613A (pt) | 1998-08-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK170893B1 (da) | Nye 5'-deoxy-5-fluorcytidinderivater, en fremgangsmåde til fremstilling deraf, farmaceutiske midler indeholdende sådanne derivater og anvendelse af derivaterne til fremstilling af et antitumormiddel | |
| CZ403392A3 (en) | Amino-substituted benzylguanidines, process of their preparation, their use as medicaments and a medicament containing thereof | |
| EP0556673A1 (de) | Ortho-substituierte Benzoylguanidine, zur Behandlung und zur Prophylaxe von Herz-Rhythmus-Störungen und von ischämisch induzierten Schäden sowie zur Inhibition der Proliferation von Zellen | |
| KR970061865A (ko) | 신규 치환된 구아니딘 유도체, 그의 제조방법, 및 그의 약제학적 용도 | |
| US8518951B2 (en) | Anti-arenaviral compounds | |
| NO20084845L (no) | 2-pyrazinonderivater for behandling av sykdom eller tilstander der inhibiering av neutrofil elastaseaktivitetet er gunstig | |
| RU96121572A (ru) | Сульфонимидамиды, способ их получения, фармацевтический состав, способ его получения, способ лечения | |
| CA2922064C (en) | Peptide-oligourea chimeric compounds and methods of their use | |
| NO20044571L (no) | Isokinolinderivater | |
| PL118755B1 (en) | Process for preparing novel derivatives of phenethanolamine | |
| HU9200335D0 (en) | Medical products with human interleukin-2 content | |
| NO952596L (no) | Orto-aminosubstituerte benzoylguandiner, fremgangsmåter for deres fremstilling, deres anvendelse som legemiddel eller diagnostikum såvel som medikamenter som inneholder dem | |
| NO964904L (no) | Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikamenter inneholdende dem | |
| AU1708299A (en) | Aza-heterocyclic compounds used to treat neurological disorders and hair loss | |
| US4666889A (en) | Method for combatting viral infections | |
| CY1272A (en) | Urea derivatives | |
| CA2364900A1 (en) | Polycyclic 2-amino-thiazole systems, method for the production thereof and medicament containing said compounds | |
| NO310188B1 (no) | Orto-substituerte benzoylguanidiner, deres fremstilling, deres anvendelse for fremstilling av medikamenter ellerdiagnostika samt medikamenter inneholdende benzoylguanidinene | |
| EP1245561B1 (en) | N-substituted benzyl or phenyl aromatic sulfamides compounds and the use thereof | |
| AU2002361990B2 (en) | Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolidines | |
| NO964905L (no) | Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen | |
| US4297373A (en) | Method of suppressing cardiac arrhythmias | |
| CN112250726B (zh) | 4-天冬氨酸取代胞嘧啶核苷化合物及其药物用途 | |
| WO2023149227A1 (ja) | 皮膚外用組成物 | |
| US3379734A (en) | N1-(benzenesulfonyl)-n-(tetrahydro-thiapyranyl)ureas |