NO964348L - CCK- eller gastrin-modulerende 5-hetrocykliske-1,5-benzodiazepiner - Google Patents

CCK- eller gastrin-modulerende 5-hetrocykliske-1,5-benzodiazepiner

Info

Publication number
NO964348L
NO964348L NO964348A NO964348A NO964348L NO 964348 L NO964348 L NO 964348L NO 964348 A NO964348 A NO 964348A NO 964348 A NO964348 A NO 964348A NO 964348 L NO964348 L NO 964348L
Authority
NO
Norway
Prior art keywords
gastrin
cck
benzodiazepines
modulating
heterocyclic
Prior art date
Application number
NO964348A
Other languages
English (en)
Other versions
NO964348D0 (no
Inventor
Christopher Joseph Aquino
Elisabeth Ellen Sugg
Jerzy Ryszard Szewczyk
Original Assignee
Glaxo Wellcome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9407433A external-priority patent/GB9407433D0/en
Priority claimed from GB9420783A external-priority patent/GB9420783D0/en
Application filed by Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc
Publication of NO964348D0 publication Critical patent/NO964348D0/no
Publication of NO964348L publication Critical patent/NO964348L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Forbindelser med den generelle formel (I) og deres fysiologiske salter, fremgangsmåter for deres fremstilling og deres anvendelse som modulatorer av effektene av gastrin og CCK.
NO964348A 1994-04-14 1996-10-11 CCK- eller gastrin-modulerende 5-hetrocykliske-1,5-benzodiazepiner NO964348L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9407433A GB9407433D0 (en) 1994-04-14 1994-04-14 Heterocyclic derivatives
GB9420783A GB9420783D0 (en) 1994-10-14 1994-10-14 Heterocyclic derivatives
PCT/US1995/004163 WO1995028419A1 (en) 1994-04-14 1995-04-12 Cck or gastrin modulating 5-heterocyclic-1,5-benzodiazepines

Publications (2)

Publication Number Publication Date
NO964348D0 NO964348D0 (no) 1996-10-11
NO964348L true NO964348L (no) 1996-12-02

Family

ID=26304703

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964348A NO964348L (no) 1994-04-14 1996-10-11 CCK- eller gastrin-modulerende 5-hetrocykliske-1,5-benzodiazepiner

Country Status (25)

Country Link
EP (1) EP0756602B1 (no)
JP (1) JPH09511223A (no)
KR (1) KR970702274A (no)
CN (1) CN1176646A (no)
AT (1) ATE181737T1 (no)
AU (1) AU697349B2 (no)
BR (1) BR9507381A (no)
CA (1) CA2186900A1 (no)
CZ (1) CZ286764B6 (no)
DE (1) DE69510545T2 (no)
DK (1) DK0756602T3 (no)
ES (1) ES2135722T3 (no)
FI (1) FI964045A (no)
GR (1) GR3031335T3 (no)
HU (1) HUT76135A (no)
IL (1) IL113365A (no)
IS (1) IS4367A (no)
MX (1) MX9604765A (no)
NO (1) NO964348L (no)
NZ (1) NZ283929A (no)
PL (1) PL180026B1 (no)
RU (1) RU2152939C1 (no)
SK (1) SK281433B6 (no)
TW (1) TW369529B (no)
WO (1) WO1995028419A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9307833D0 (en) * 1993-04-15 1993-06-02 Glaxo Inc Modulators of cholecystokinin and gastrin
PE27497A1 (es) * 1994-04-15 1997-08-07 Glaxo Inc Derivados de 1,5 benzodiazepina
AU721081B2 (en) * 1996-12-10 2000-06-22 Zeria Pharmaceutical Co., Ltd. 1,5-benzodiazepine derivatives
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
CA2347938A1 (en) * 1998-10-20 2000-04-27 Takahiro Matsumoto 1,5-benzodiazepine compounds, their production and use
JP4535350B2 (ja) * 1998-11-17 2010-09-01 クミアイ化学工業株式会社 ピリミジニルベンズイミダゾール誘導体及び農園芸用殺菌剤
CN1678314A (zh) * 2002-08-27 2005-10-05 默克专利有限公司 作为raf－激酶抑制剂的甘氨酸酰胺衍生物
BRPI0510273A (pt) 2004-05-25 2007-10-30 Pfizer Prod Inc derivados de tetraazabenzo[e]azuleno e análogos destes
KR102092147B1 (ko) 2012-01-13 2020-03-23 닛뽕 케미파 가부시키가이샤 P2x4 수용체 길항제
US9815850B2 (en) 2016-02-05 2017-11-14 Denali Therapeutics Inc. Compounds, compositions and methods
PL3552017T3 (pl) 2016-12-09 2022-08-08 Denali Therapeutics Inc. Związki użyteczne jako inhibitory RIPK1
WO2021071837A1 (en) 2019-10-07 2021-04-15 Kallyope, Inc. Gpr119 agonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641280B1 (fr) * 1988-12-29 1994-01-21 Roussel Uclaf Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments
GEP20001968B (en) * 1992-01-21 2000-03-05 Glaxo Spa Arilthio Compounds as Antibacterial and Antiviral Agents
GB9307833D0 (en) * 1993-04-15 1993-06-02 Glaxo Inc Modulators of cholecystokinin and gastrin

Also Published As

Publication number Publication date
CZ286764B6 (en) 2000-06-14
SK281433B6 (sk) 2001-03-12
IL113365A (en) 1999-11-30
CN1176646A (zh) 1998-03-18
PL180026B1 (pl) 2000-12-29
RU2152939C1 (ru) 2000-07-20
FI964045A0 (fi) 1996-10-09
EP0756602B1 (en) 1999-06-30
HU9602835D0 (en) 1996-12-30
TW369529B (en) 1999-09-11
IS4367A (is) 1996-09-30
NZ283929A (en) 1998-02-26
HUT76135A (en) 1997-06-30
ATE181737T1 (de) 1999-07-15
FI964045A (fi) 1996-10-09
KR970702274A (ko) 1997-05-13
ES2135722T3 (es) 1999-11-01
IL113365A0 (en) 1995-07-31
PL316870A1 (en) 1997-02-17
MX9604765A (es) 1998-05-31
WO1995028419A1 (en) 1995-10-26
GR3031335T3 (en) 1999-12-31
SK130096A3 (en) 1997-08-06
DE69510545D1 (de) 1999-08-05
BR9507381A (pt) 1997-09-23
CA2186900A1 (en) 1995-10-26
AU2239095A (en) 1995-11-10
CZ297296A3 (en) 1997-09-17
JPH09511223A (ja) 1997-11-11
NO964348D0 (no) 1996-10-11
DE69510545T2 (de) 2000-01-13
EP0756602A1 (en) 1997-02-05
AU697349B2 (en) 1998-10-01
DK0756602T3 (da) 2000-01-31

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