NO964231L - Stabil vandig folinatopplösning - Google Patents

Stabil vandig folinatopplösning

Info

Publication number
NO964231L
NO964231L NO964231A NO964231A NO964231L NO 964231 L NO964231 L NO 964231L NO 964231 A NO964231 A NO 964231A NO 964231 A NO964231 A NO 964231A NO 964231 L NO964231 L NO 964231L
Authority
NO
Norway
Prior art keywords
stable aqueous
folinate solution
aqueous folinate
solution
aqueous solution
Prior art date
Application number
NO964231A
Other languages
English (en)
Other versions
NO314039B1 (no
NO964231D0 (no
Inventor
Alfred James Nijkerk
Johanna Maria Pieterne Vermeer
Original Assignee
Pharmachemie Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv
Publication of NO964231D0 publication Critical patent/NO964231D0/no
Publication of NO964231L publication Critical patent/NO964231L/no
Publication of NO314039B1 publication Critical patent/NO314039B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO19964231A 1994-04-05 1996-10-04 Stabil vandig folinatopplösning NO314039B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9400530A NL9400530A (nl) 1994-04-05 1994-04-05 Stabiele waterige folinaatoplossing.
PCT/NL1995/000126 WO1995026963A1 (en) 1994-04-05 1995-04-04 Stable aqueous folinate solution

Publications (3)

Publication Number Publication Date
NO964231D0 NO964231D0 (no) 1996-10-04
NO964231L true NO964231L (no) 1996-10-04
NO314039B1 NO314039B1 (no) 2003-01-20

Family

ID=19864026

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19964231A NO314039B1 (no) 1994-04-05 1996-10-04 Stabil vandig folinatopplösning

Country Status (15)

Country Link
US (1) US6613767B1 (no)
EP (1) EP0755396B1 (no)
JP (1) JPH09510989A (no)
AT (1) ATE194346T1 (no)
AU (1) AU684350B2 (no)
DE (1) DE69517806T2 (no)
DK (1) DK0755396T3 (no)
ES (1) ES2149354T3 (no)
FI (1) FI120039B (no)
GR (1) GR3033863T3 (no)
NL (1) NL9400530A (no)
NO (1) NO314039B1 (no)
PT (1) PT755396E (no)
WO (1) WO1995026963A1 (no)
ZA (1) ZA952805B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH687062A5 (de) * 1994-02-14 1996-09-13 Cerbios Pharma Sa Konzentrierte Injektionsloesung von Alkalimetallsalzen von reduzierten Folaten.
NL9400530A (nl) 1994-04-05 1995-11-01 Pharmachemie Bv Stabiele waterige folinaatoplossing.
CH697021A5 (de) * 2003-06-26 2008-03-31 Merck Eprova Ag Stabile pharmazeutische Zusammensetzungen von 5, 10-Methylentetrahydrofolat.
CH696717A5 (de) * 2004-02-20 2007-10-31 Cerbios Pharma Sa Konzentrierte, stabile Losung, insbesondere eine Injektionslosung oder Infusionslosung, welche nebst Wasser entweder (6S)-Natrium-Folinat oder (6S)-Kalium-Folinat entholt
CN102258463A (zh) * 2011-07-18 2011-11-30 重庆煜澍丰医药有限公司 一种稳定的亚叶酸钠注射液
ES2414557B1 (es) * 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
WO2014025807A1 (en) 2012-08-06 2014-02-13 Spectrum Pharmaceuticals, Inc. Pharmaceutical compositions comprising l-leucovorin
US10059710B2 (en) 2016-02-17 2018-08-28 Merck & Cie Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2695860A (en) * 1952-04-29 1954-11-30 American Cyanamid Co Stabilized pteroyl solutions
CH673459A5 (no) 1987-05-15 1990-03-15 Eprova Ag
WO1990010460A1 (en) 1989-03-13 1990-09-20 Kenneth Naoyuki Matsumura Method for reducing side effects of a drug
NL8901432A (nl) * 1989-06-06 1991-01-02 Pharmachemie Bv Bij koelkasttemperatuur stabiele waterige folinaatoplossing, alsmede werkwijze ter bereiding daarvan.
US5173488A (en) * 1989-08-21 1992-12-22 American Cyanamid Company Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method
CH687062A5 (de) 1994-02-14 1996-09-13 Cerbios Pharma Sa Konzentrierte Injektionsloesung von Alkalimetallsalzen von reduzierten Folaten.
NL9400530A (nl) 1994-04-05 1995-11-01 Pharmachemie Bv Stabiele waterige folinaatoplossing.

Also Published As

Publication number Publication date
EP0755396A1 (en) 1997-01-29
JPH09510989A (ja) 1997-11-04
NL9400530A (nl) 1995-11-01
FI963972A0 (fi) 1996-10-03
PT755396E (pt) 2000-10-31
EP0755396B1 (en) 2000-07-05
FI963972A (fi) 1996-10-03
DE69517806T2 (de) 2001-11-08
NO314039B1 (no) 2003-01-20
GR3033863T3 (en) 2000-10-31
AU2086295A (en) 1995-10-23
ES2149354T3 (es) 2000-11-01
FI120039B (fi) 2009-06-15
DE69517806D1 (de) 2000-08-10
ZA952805B (en) 1995-12-19
NO964231D0 (no) 1996-10-04
ATE194346T1 (de) 2000-07-15
AU684350B2 (en) 1997-12-11
WO1995026963A1 (en) 1995-10-12
DK0755396T3 (da) 2000-11-13
US6613767B1 (en) 2003-09-02

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