ES8605538A1 - Procedimiento para la preparacion de nonapeptidos y dodecapeptidos - Google Patents

Procedimiento para la preparacion de nonapeptidos y dodecapeptidos

Info

Publication number
ES8605538A1
ES8605538A1 ES536795A ES536795A ES8605538A1 ES 8605538 A1 ES8605538 A1 ES 8605538A1 ES 536795 A ES536795 A ES 536795A ES 536795 A ES536795 A ES 536795A ES 8605538 A1 ES8605538 A1 ES 8605538A1
Authority
ES
Spain
Prior art keywords
dodecapeptides
natural killer
cell activity
killer cell
nona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES536795A
Other languages
English (en)
Other versions
ES536795A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES8605538A1 publication Critical patent/ES8605538A1/es
Publication of ES536795A0 publication Critical patent/ES536795A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C7/00—Purification; Separation; Use of additives
    • C07C7/04—Purification; Separation; Use of additives by distillation
    • C07C7/05—Purification; Separation; Use of additives by distillation with the aid of auxiliary compounds
    • C07C7/06—Purification; Separation; Use of additives by distillation with the aid of auxiliary compounds by azeotropic distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NONAPEPTIDOS Y DODECAPEPTIDOS. COMPRENDE: A) HACER REACCIONAR UN COMPUESTO INTERMEDIO DE PEPTIDO PROTEINICO, FIJADO EN FASE SOLIDA A UNA RESINA DE FORMULA (II) CON UN AGENTE DESPROTECTOR COMO F2H2 Y A UNA TEMPERATURA ENTRE 0J Y 50JC PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDOS ACEPTABLES Y NO TOXICOS SIENDO: X, N-ACIL-GLN O N-ACIL-CYS-TYR-CYS-GLU Y OTROS; Y GLY, GLU O CLYN(R)2; R ES H O ALQUILO DE C 1 A 6, Y ACIL ES UN RADICAL DE UN ACIDO ALQUIL-CARBOXILICO DE C 1 A 6 O ACIDO BENZOICO. SE UTILIZAN PARA AUMENTAR LA ACTIVIDAD DE CELULAS MATADORAS NATURALES.
ES536795A 1983-10-17 1984-10-16 Procedimiento para la preparacion de nonapeptidos y dodecapeptidos Expired ES8605538A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/542,632 US4473555A (en) 1983-10-17 1983-10-17 Nona- and dodecapeptides for augmenting natural killer cell activity

Publications (2)

Publication Number Publication Date
ES8605538A1 true ES8605538A1 (es) 1986-04-01
ES536795A0 ES536795A0 (es) 1986-04-01

Family

ID=24164663

Family Applications (1)

Application Number Title Priority Date Filing Date
ES536795A Expired ES8605538A1 (es) 1983-10-17 1984-10-16 Procedimiento para la preparacion de nonapeptidos y dodecapeptidos

Country Status (13)

Country Link
US (1) US4473555A (es)
EP (1) EP0138616A3 (es)
JP (1) JPS6087299A (es)
KR (1) KR850003416A (es)
AU (1) AU3428784A (es)
DK (1) DK495484A (es)
ES (1) ES8605538A1 (es)
FI (1) FI844068L (es)
HU (1) HUT35695A (es)
IL (1) IL73256A0 (es)
NO (1) NO844123L (es)
PL (1) PL250044A1 (es)
ZA (1) ZA848070B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019384A (en) * 1986-06-30 1991-05-28 Massachusetts Institute Of Technology Immunonodulating compositions and their use
JP2633881B2 (ja) 1986-06-30 1997-07-23 マサチューセッツ インスティテュート オブ テクノロジー 免疫調節組成物及びそれらの使用
US5457038A (en) * 1988-11-10 1995-10-10 Genetics Institute, Inc. Natural killer stimulatory factor
WO1990005147A1 (en) * 1988-11-10 1990-05-17 Genetics Institute, Inc. Natural killer stimulatory factor
US5811523A (en) 1988-11-10 1998-09-22 Trinchieri; Giorgio Antibodies to natural killer stimulatory factor
IT1231727B (it) * 1989-08-11 1991-12-21 Enrico Savoldi Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.
CA2042027A1 (en) * 1989-09-15 1991-03-16 Arthur E. Bogden Treatment of colon cancer
US6683046B1 (en) 1989-12-22 2004-01-27 Hoffmann-La Roche Inc. Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto
US7026456B1 (en) 1998-01-23 2006-04-11 Hoffman-La Roche, Inc. Antibodies against human IL-12
GB0211849D0 (en) * 2002-05-23 2002-07-03 Mok Kenneth H Improvments to retro-inverso isomers
EP4162925A1 (en) * 2020-06-08 2023-04-12 Ninebiopharm Co., Ltd. Composition comprising regentide-034 and regentide-041 for skin care or wrinkle reduction

Also Published As

Publication number Publication date
IL73256A0 (en) 1985-01-31
PL250044A1 (en) 1985-06-04
US4473555A (en) 1984-09-25
EP0138616A2 (en) 1985-04-24
NO844123L (no) 1985-04-18
AU3428784A (en) 1985-04-26
ES536795A0 (es) 1986-04-01
DK495484A (da) 1985-04-18
EP0138616A3 (en) 1987-06-16
FI844068L (fi) 1985-04-18
HUT35695A (en) 1985-07-29
FI844068A0 (fi) 1984-10-16
ZA848070B (en) 1986-05-28
JPS6087299A (ja) 1985-05-16
DK495484D0 (da) 1984-10-16
KR850003416A (ko) 1985-06-17

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