ES8801673A1 - Un procedimiento para la preparacion de derivados peptidicos de histidinilprolinamida. - Google Patents
Un procedimiento para la preparacion de derivados peptidicos de histidinilprolinamida.Info
- Publication number
- ES8801673A1 ES8801673A1 ES557149A ES557149A ES8801673A1 ES 8801673 A1 ES8801673 A1 ES 8801673A1 ES 557149 A ES557149 A ES 557149A ES 557149 A ES557149 A ES 557149A ES 8801673 A1 ES8801673 A1 ES 8801673A1
- Authority
- ES
- Spain
- Prior art keywords
- processes
- production
- novel peptides
- compositions containing
- peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS PEPTIDICOS DE HISTIDINILPROLINAMIDA. CONSISTE EN CONDENSAR UN COMPUESTO DE FORMULA (II) CON UN PROLINAMIDA DE FORMULA (III),EN PRESENCIA DE UN ACEPTOR DE ACIDO (HIDROXIDO SODICO), EN UN DISOLVENTE (TETRAHIDROFURANO) Y ENTRE C30 Y B50JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SU SAL FARMACEUTICAMENTE ACEPTABLE. SIENDO: R, H O ALQUILO INFERIOR; X1, UN GRUPO IMINO O UN GRUPO ALQUILIMINO INFERIOR; X2, UN GRUPO IMINO; Y X3, UN GRUPO IMINO O UNA SAL DEL MISMO. SE UTILIZA PARA EL TRATAMIENTO DE LOS TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08504357A GB2171101A (en) | 1985-02-20 | 1985-02-20 | Peptide and processes for preparation of the same |
Publications (2)
Publication Number | Publication Date |
---|---|
ES557149A0 ES557149A0 (es) | 1988-02-16 |
ES8801673A1 true ES8801673A1 (es) | 1988-02-16 |
Family
ID=10574792
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552193A Expired ES8705464A1 (es) | 1985-02-20 | 1986-02-19 | Un procedimiento para la preparacion de nuevos peptidos. |
ES557149A Expired ES8801673A1 (es) | 1985-02-20 | 1986-10-27 | Un procedimiento para la preparacion de derivados peptidicos de histidinilprolinamida. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552193A Expired ES8705464A1 (es) | 1985-02-20 | 1986-02-19 | Un procedimiento para la preparacion de nuevos peptidos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4711878A (es) |
EP (1) | EP0194443B1 (es) |
JP (1) | JPS61191695A (es) |
AT (1) | ATE45958T1 (es) |
CA (1) | CA1265898A (es) |
DE (1) | DE3665309D1 (es) |
ES (2) | ES8705464A1 (es) |
GB (1) | GB2171101A (es) |
HK (1) | HK1591A (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL75641A (en) * | 1984-07-10 | 1990-11-05 | Tanabe Seiyaku Co | 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it |
US5686420A (en) * | 1987-06-05 | 1997-11-11 | Georgetown University | Thyrotropin-releasing hormone analogs and method of use |
JPS63316724A (ja) * | 1987-06-19 | 1988-12-26 | Nippon Shinyaku Co Ltd | 抗けいれん剤 |
US7462595B2 (en) * | 2004-09-17 | 2008-12-09 | Prange Jr Arthur Jergen | Methods for treating cancer-related fatigue |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE408300B (sv) * | 1974-10-16 | 1979-06-05 | Gruenenthal Chemie | Sett att framstella nya dipeptidderivat |
JPS51118841A (en) * | 1975-04-03 | 1976-10-19 | Takeda Chem Ind Ltd | A drug for improving and treating clouding of consciousness |
JPS5944308B2 (ja) * | 1976-03-23 | 1984-10-29 | 武田薬品工業株式会社 | ペプタイド |
-
1985
- 1985-02-20 GB GB08504357A patent/GB2171101A/en not_active Withdrawn
-
1986
- 1986-02-05 US US06/826,265 patent/US4711878A/en not_active Expired - Fee Related
- 1986-02-06 AT AT86101515T patent/ATE45958T1/de not_active IP Right Cessation
- 1986-02-06 DE DE8686101515T patent/DE3665309D1/de not_active Expired
- 1986-02-06 EP EP86101515A patent/EP0194443B1/en not_active Expired
- 1986-02-14 JP JP61031450A patent/JPS61191695A/ja active Granted
- 1986-02-19 ES ES552193A patent/ES8705464A1/es not_active Expired
- 1986-02-20 CA CA000502312A patent/CA1265898A/en not_active Expired - Fee Related
- 1986-10-27 ES ES557149A patent/ES8801673A1/es not_active Expired
-
1991
- 1991-01-03 HK HK15/91A patent/HK1591A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB2171101A (en) | 1986-08-20 |
GB8504357D0 (en) | 1985-03-20 |
ES557149A0 (es) | 1988-02-16 |
EP0194443A3 (en) | 1987-09-23 |
ES8705464A1 (es) | 1987-05-01 |
EP0194443B1 (en) | 1989-08-30 |
CA1265898A (en) | 1990-02-13 |
ATE45958T1 (de) | 1989-09-15 |
JPH0564960B2 (es) | 1993-09-16 |
US4711878A (en) | 1987-12-08 |
JPS61191695A (ja) | 1986-08-26 |
EP0194443A2 (en) | 1986-09-17 |
HK1591A (en) | 1991-01-11 |
DE3665309D1 (en) | 1989-10-05 |
ES552193A0 (es) | 1987-05-01 |
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