ES8707217A1 - Un procedimiento para preparar un derivado de 1,5-benzotiazepina - Google Patents

Un procedimiento para preparar un derivado de 1,5-benzotiazepina

Info

Publication number
ES8707217A1
ES8707217A1 ES556551A ES556551A ES8707217A1 ES 8707217 A1 ES8707217 A1 ES 8707217A1 ES 556551 A ES556551 A ES 556551A ES 556551 A ES556551 A ES 556551A ES 8707217 A1 ES8707217 A1 ES 8707217A1
Authority
ES
Spain
Prior art keywords
novel
lower alkyl
preparing
processes
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556551A
Other languages
English (en)
Other versions
ES556551A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848410949A external-priority patent/GB8410949D0/en
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of ES556551A0 publication Critical patent/ES556551A0/es
Publication of ES8707217A1 publication Critical patent/ES8707217A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE 1,5-BENZOTIAZEPINA. CONSISTE EN CONDENSAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (R5COOH), EN PRESENCIA DE PIRIDINA O TRIETILAMINA, EN DIOXANO O BENCENO Y ENTRE 20 Y 130JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: Q, H; R1, ALQUILO O ALCOXI INFERIOR; R2, ALCANOILA INFERIOR O BENZOILO; R3, ALQUILO INFERIOR; R4, ALQUILO INFERIOR, HAL Y OTROS; Y R5, ALQUILO INFERIOR O FENILO. SE UTILIZA PARA TRATAR LAS ENFERMEDADES TROMBOTICAS.
ES556551A 1984-04-10 1986-06-24 Un procedimiento para preparar un derivado de 1,5-benzotiazepina Expired ES8707217A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8409259 1984-04-10
GB848410949A GB8410949D0 (en) 1984-04-28 1984-04-28 1 5-benzothiazepine derivatives

Publications (2)

Publication Number Publication Date
ES556551A0 ES556551A0 (es) 1987-07-16
ES8707217A1 true ES8707217A1 (es) 1987-07-16

Family

ID=26287601

Family Applications (3)

Application Number Title Priority Date Filing Date
ES542126A Expired ES8705410A1 (es) 1984-04-10 1985-04-10 Un procedimiento para preparar un derivado de 1,5 beurotiarepina.
ES556552A Expired ES8800920A1 (es) 1984-04-10 1986-06-24 Un procedimiento para preparar un derivado de 1,5-benzotiazepina
ES556551A Expired ES8707217A1 (es) 1984-04-10 1986-06-24 Un procedimiento para preparar un derivado de 1,5-benzotiazepina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES542126A Expired ES8705410A1 (es) 1984-04-10 1985-04-10 Un procedimiento para preparar un derivado de 1,5 beurotiarepina.
ES556552A Expired ES8800920A1 (es) 1984-04-10 1986-06-24 Un procedimiento para preparar un derivado de 1,5-benzotiazepina

Country Status (7)

Country Link
US (1) US4594342A (es)
EP (1) EP0158340B1 (es)
KR (1) KR900005680B1 (es)
AT (1) ATE40127T1 (es)
CA (1) CA1218992A (es)
DE (1) DE3567651D1 (es)
ES (3) ES8705410A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
FR2630107B1 (fr) * 1988-04-19 1990-06-08 Synthelabo Procede de preparation du (+) - (2s,3s) (amino-2 phenyl)thio)-3 hydroxy-2 (methoxy-4 phenyl)-3 propionate de methyle
US5002942A (en) * 1988-07-25 1991-03-26 Sankyo Company, Limited 1,5-benzothiazepine derivatives, their preparation and their use in the treatment of cardiovascular disorders
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
IT1240651B (it) * 1990-05-17 1993-12-17 Zambon Spa Processo per la risoluzione di derivati glicidici
CA2049655C (en) * 1990-09-17 1996-11-12 Akio Odawara Pharmaceutical composition for inhibiting platelet aggregation
US5378698A (en) * 1991-10-21 1995-01-03 Shionogi & Co., Ltd. Benzothiazepine derivatives
SG48753A1 (en) * 1992-10-23 1998-05-18 Tanabe Seiyaku Co Peripheral circulation improving method
US5637582A (en) * 1992-10-23 1997-06-10 Tanabe Seiyaku Co., Ltd. Peripheral circulation improving agent
IT1302261B1 (it) 1998-09-24 2000-09-05 Zambon Spa Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) * 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3341519A (en) * 1965-04-28 1967-09-12 Squibb & Sons Inc Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS56156218A (en) * 1980-05-02 1981-12-02 Tanabe Seiyaku Co Ltd Inhibitor against blood platelet agglutination
JPS56156217A (en) * 1980-05-02 1981-12-02 Tanabe Seiyaku Co Ltd Inhibitor against blood platelet agglutination
US5708066A (en) * 1995-03-01 1998-01-13 E. I. Du Pont De Nemours And Company Reaction curable composition and solid surface material

Also Published As

Publication number Publication date
ES542126A0 (es) 1987-05-01
KR900005680B1 (ko) 1990-08-06
EP0158340B1 (en) 1989-01-18
ES556551A0 (es) 1987-07-16
EP0158340A3 (en) 1986-05-28
ES556552A0 (es) 1987-12-01
ATE40127T1 (de) 1989-02-15
KR850007249A (ko) 1985-12-02
US4594342A (en) 1986-06-10
EP0158340A2 (en) 1985-10-16
DE3567651D1 (en) 1989-02-23
ES8800920A1 (es) 1987-12-01
CA1218992A (en) 1987-03-10
ES8705410A1 (es) 1987-05-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020401