NO961719L - 3-aryl-4-alkyl og 4,5-dialkyl-4H-1,2,4-triazoler som er anvendbare som hukommelsesforsterkere - Google Patents
3-aryl-4-alkyl og 4,5-dialkyl-4H-1,2,4-triazoler som er anvendbare som hukommelsesforsterkereInfo
- Publication number
- NO961719L NO961719L NO961719A NO961719A NO961719L NO 961719 L NO961719 L NO 961719L NO 961719 A NO961719 A NO 961719A NO 961719 A NO961719 A NO 961719A NO 961719 L NO961719 L NO 961719L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- dialkyl
- aryl
- lower alkyl
- memory enhancers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår økning av hukommelse og erkjennelse og behandling av Alzheimer's sykdom og Wernicke-Korsakoff-syndrom ved admin- istrering av 3-aryl-4-alkyl og 4,5- dialkyl-4H-l,2,4-triazoler av formel (D (D hvori R. og R_ uavhengig betegner hydrogen, halogen, trifluormethyl, nitro, C, .-lavere alkyl eller C,_.-lavere alkoxy, eller hvori R, og R_ sammen betegner -CH=CH-CH=CH-, under dannelse av et l- eller 2- nafthylenylringsystem; R, betegner hydrogen eller C,.-lavere alkyl; og R. betegner C,_.-lavere alkyl, benzyl eller benzyl substituert med en eller to grupper valgt fra halo- gen, trifluormethyl, nitro, C,_.- lavere alkyl eller C, .-lavere alkoksy.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14637393A | 1993-10-29 | 1993-10-29 | |
| PCT/US1994/011255 WO1995011887A1 (en) | 1993-10-29 | 1994-10-04 | 3-aryl-4-alkyl and 4,5-dialkyl-4h-1,2,4-triazoles useful as memory enhancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO961719D0 NO961719D0 (no) | 1996-04-29 |
| NO961719L true NO961719L (no) | 1996-04-29 |
Family
ID=22517085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO961719A NO961719L (no) | 1993-10-29 | 1996-04-29 | 3-aryl-4-alkyl og 4,5-dialkyl-4H-1,2,4-triazoler som er anvendbare som hukommelsesforsterkere |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0725776B1 (no) |
| JP (1) | JP3779990B2 (no) |
| KR (1) | KR100321885B1 (no) |
| CN (1) | CN1046273C (no) |
| AT (1) | ATE155462T1 (no) |
| AU (1) | AU679130B2 (no) |
| CA (1) | CA2175352C (no) |
| DE (1) | DE69404322T2 (no) |
| DK (1) | DK0725776T3 (no) |
| ES (1) | ES2106567T3 (no) |
| FI (1) | FI961793A (no) |
| GR (1) | GR3024747T3 (no) |
| HU (1) | HUT74693A (no) |
| IL (1) | IL111404A (no) |
| NO (1) | NO961719L (no) |
| NZ (1) | NZ275620A (no) |
| WO (1) | WO1995011887A1 (no) |
| ZA (1) | ZA948352B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012240329A1 (en) | 2011-04-04 | 2013-10-10 | The Procter & Gamble Company | Personal care article |
| CN104202987B (zh) | 2011-08-15 | 2017-09-01 | 宝洁公司 | 个人护理方法 |
| CN103717727A (zh) | 2011-08-15 | 2014-04-09 | 宝洁公司 | 具有包含适形个人护理组合物的多个区域的个人护理制品 |
| US9855203B2 (en) | 2013-06-27 | 2018-01-02 | The Procter & Gamble Company | Preserving personal care compositions |
| EP3653611A1 (en) * | 2018-11-15 | 2020-05-20 | Centre National De La Recherche Scientifique | Inhibitors of metallo-beta-lactamases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE541700C (de) * | 1928-04-08 | 1932-01-15 | C H Boehringer Sohn Akt Ges | Verfahren zur Darstellung von 1,2,4-Triazolen |
| AR243171A1 (es) * | 1985-10-29 | 1993-07-30 | Merrell Pharma Inc | Procedimiento para preparar 5-aril-2,4-dialquil-3h-1,2,4-triazol-3-tionas. |
| US5100906A (en) * | 1990-04-19 | 1992-03-31 | Merrell Dow Pharmaceuticals Inc. | 5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers |
| US5054050A (en) * | 1990-04-30 | 1991-10-01 | American Telephone & Telegraph Co. | Drop testing in fiber to the home systems |
-
1994
- 1994-10-04 CA CA002175352A patent/CA2175352C/en not_active Expired - Fee Related
- 1994-10-04 KR KR1019960702351A patent/KR100321885B1/ko not_active IP Right Cessation
- 1994-10-04 WO PCT/US1994/011255 patent/WO1995011887A1/en active IP Right Grant
- 1994-10-04 EP EP94930582A patent/EP0725776B1/en not_active Expired - Lifetime
- 1994-10-04 AU AU79654/94A patent/AU679130B2/en not_active Ceased
- 1994-10-04 NZ NZ275620A patent/NZ275620A/xx unknown
- 1994-10-04 DE DE69404322T patent/DE69404322T2/de not_active Expired - Fee Related
- 1994-10-04 HU HU9601114A patent/HUT74693A/hu unknown
- 1994-10-04 CN CN94193957A patent/CN1046273C/zh not_active Expired - Fee Related
- 1994-10-04 ES ES94930582T patent/ES2106567T3/es not_active Expired - Lifetime
- 1994-10-04 DK DK94930582.5T patent/DK0725776T3/da active
- 1994-10-04 AT AT94930582T patent/ATE155462T1/de not_active IP Right Cessation
- 1994-10-04 JP JP51264595A patent/JP3779990B2/ja not_active Expired - Fee Related
- 1994-10-24 ZA ZA948352A patent/ZA948352B/xx unknown
- 1994-10-26 IL IL11140494A patent/IL111404A/xx not_active IP Right Cessation
-
1996
- 1996-04-26 FI FI961793A patent/FI961793A/fi not_active IP Right Cessation
- 1996-04-29 NO NO961719A patent/NO961719L/no not_active Application Discontinuation
-
1997
- 1997-09-17 GR GR970402392T patent/GR3024747T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69404322D1 (de) | 1997-08-21 |
| JPH09504290A (ja) | 1997-04-28 |
| FI961793A0 (fi) | 1996-04-26 |
| IL111404A (en) | 2000-02-17 |
| KR960705791A (ko) | 1996-11-08 |
| DE69404322T2 (de) | 1997-10-30 |
| CA2175352C (en) | 1999-03-02 |
| ZA948352B (en) | 1995-06-26 |
| CN1046273C (zh) | 1999-11-10 |
| WO1995011887A1 (en) | 1995-05-04 |
| GR3024747T3 (en) | 1997-12-31 |
| AU679130B2 (en) | 1997-06-19 |
| KR100321885B1 (ko) | 2002-06-24 |
| AU7965494A (en) | 1995-05-22 |
| ES2106567T3 (es) | 1997-11-01 |
| EP0725776B1 (en) | 1997-07-16 |
| NO961719D0 (no) | 1996-04-29 |
| ATE155462T1 (de) | 1997-08-15 |
| DK0725776T3 (da) | 1997-09-01 |
| IL111404A0 (en) | 1994-12-29 |
| NZ275620A (en) | 1999-01-28 |
| CN1134147A (zh) | 1996-10-23 |
| HU9601114D0 (en) | 1996-07-29 |
| JP3779990B2 (ja) | 2006-05-31 |
| EP0725776A1 (en) | 1996-08-14 |
| CA2175352A1 (en) | 1995-05-04 |
| FI961793A (fi) | 1996-04-26 |
| HUT74693A (en) | 1997-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |