DE69404322D1 - 3-aryl-4-alkyl und 4,5-dialkyl-4h-1,2,4-triazole, verwendbar gegen gedächtnis-störungen - Google Patents

3-aryl-4-alkyl und 4,5-dialkyl-4h-1,2,4-triazole, verwendbar gegen gedächtnis-störungen

Info

Publication number
DE69404322D1
DE69404322D1 DE69404322T DE69404322T DE69404322D1 DE 69404322 D1 DE69404322 D1 DE 69404322D1 DE 69404322 T DE69404322 T DE 69404322T DE 69404322 T DE69404322 T DE 69404322T DE 69404322 D1 DE69404322 D1 DE 69404322D1
Authority
DE
Germany
Prior art keywords
alkyl
triazoles
dialkyl
aryl
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69404322T
Other languages
English (en)
Other versions
DE69404322T2 (de
Inventor
Christopher DALTON
John Kane
Jerry Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69404322D1 publication Critical patent/DE69404322D1/de
Publication of DE69404322T2 publication Critical patent/DE69404322T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69404322T 1993-10-29 1994-10-04 3-aryl-4-alkyl und 4,5-dialkyl-4h-1,2,4-triazole, verwendbar gegen gedächtnis-störungen Expired - Fee Related DE69404322T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14637393A 1993-10-29 1993-10-29
PCT/US1994/011255 WO1995011887A1 (en) 1993-10-29 1994-10-04 3-aryl-4-alkyl and 4,5-dialkyl-4h-1,2,4-triazoles useful as memory enhancers

Publications (2)

Publication Number Publication Date
DE69404322D1 true DE69404322D1 (de) 1997-08-21
DE69404322T2 DE69404322T2 (de) 1997-10-30

Family

ID=22517085

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69404322T Expired - Fee Related DE69404322T2 (de) 1993-10-29 1994-10-04 3-aryl-4-alkyl und 4,5-dialkyl-4h-1,2,4-triazole, verwendbar gegen gedächtnis-störungen

Country Status (18)

Country Link
EP (1) EP0725776B1 (de)
JP (1) JP3779990B2 (de)
KR (1) KR100321885B1 (de)
CN (1) CN1046273C (de)
AT (1) ATE155462T1 (de)
AU (1) AU679130B2 (de)
CA (1) CA2175352C (de)
DE (1) DE69404322T2 (de)
DK (1) DK0725776T3 (de)
ES (1) ES2106567T3 (de)
FI (1) FI961793A0 (de)
GR (1) GR3024747T3 (de)
HU (1) HUT74693A (de)
IL (1) IL111404A (de)
NO (1) NO961719L (de)
NZ (1) NZ275620A (de)
WO (1) WO1995011887A1 (de)
ZA (1) ZA948352B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2693928B1 (de) 2011-04-04 2018-09-05 The Procter and Gamble Company Haushaltspflegeartikel
CN104202987B (zh) 2011-08-15 2017-09-01 宝洁公司 个人护理方法
MX355294B (es) 2011-08-15 2018-04-12 Procter & Gamble Artículos para el cuidado personal que tienen composiciones para el cuidado personal que tienen múltiples zonas amoldables.
BR112015032541A2 (pt) 2013-06-27 2017-07-25 Procter & Gamble conservação de composições para cuidados pessoais
EP3653611A1 (de) * 2018-11-15 2020-05-20 Centre National De La Recherche Scientifique Metallo-beta-lactamase inhibitoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE541700C (de) * 1928-04-08 1932-01-15 C H Boehringer Sohn Akt Ges Verfahren zur Darstellung von 1,2,4-Triazolen
AR243171A1 (es) * 1985-10-29 1993-07-30 Merrell Pharma Inc Procedimiento para preparar 5-aril-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
US5100906A (en) * 1990-04-19 1992-03-31 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers
US5054050A (en) * 1990-04-30 1991-10-01 American Telephone & Telegraph Co. Drop testing in fiber to the home systems

Also Published As

Publication number Publication date
DE69404322T2 (de) 1997-10-30
EP0725776A1 (de) 1996-08-14
HUT74693A (en) 1997-01-28
IL111404A (en) 2000-02-17
ES2106567T3 (es) 1997-11-01
NZ275620A (en) 1999-01-28
ATE155462T1 (de) 1997-08-15
FI961793A (fi) 1996-04-26
NO961719D0 (no) 1996-04-29
JP3779990B2 (ja) 2006-05-31
GR3024747T3 (en) 1997-12-31
CA2175352A1 (en) 1995-05-04
CN1046273C (zh) 1999-11-10
WO1995011887A1 (en) 1995-05-04
CN1134147A (zh) 1996-10-23
JPH09504290A (ja) 1997-04-28
FI961793A0 (fi) 1996-04-26
HU9601114D0 (en) 1996-07-29
IL111404A0 (en) 1994-12-29
AU7965494A (en) 1995-05-22
DK0725776T3 (da) 1997-09-01
KR100321885B1 (ko) 2002-06-24
KR960705791A (ko) 1996-11-08
AU679130B2 (en) 1997-06-19
EP0725776B1 (de) 1997-07-16
NO961719L (no) 1996-04-29
ZA948352B (en) 1995-06-26
CA2175352C (en) 1999-03-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS INC. (N.D.GES.D. STAATES PENNSYLVANIA), GR

8339 Ceased/non-payment of the annual fee