ES2074884T3 - Agentes neuroprotectores. - Google Patents
Agentes neuroprotectores.Info
- Publication number
- ES2074884T3 ES2074884T3 ES92907045T ES92907045T ES2074884T3 ES 2074884 T3 ES2074884 T3 ES 2074884T3 ES 92907045 T ES92907045 T ES 92907045T ES 92907045 T ES92907045 T ES 92907045T ES 2074884 T3 ES2074884 T3 ES 2074884T3
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- agents
- neuroprotecting agents
- neuroprotecting
- perhaloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
ESTE INVENTO TRATA DE NUEVOS AGENTES NEUROPROTECTORES DE FORMULA (I) EN LA QUE R1 Y R3 SON INDEPENDIENTEMENTE, HIDROGENO, CIANO, NITRO, HALO O PERHALOALQUIL, CON LA CONDICION DE QUE R1 O R3 SEA DISTINTO DEL HIDROGENO; R2 ES ALQUIL; SE DESCRIBEN ESTOS AGENTES O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS, PROCESO PARA PREPARARLOS, COMPOSICIONES QUE LO CONTIENEN Y SU EMPLEO COMO ANTAGONISTAS NMDA .
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/658,283 US5508401A (en) | 1991-02-20 | 1991-02-20 | Substituted dibenzo[a,d]cycloheptene NMDA antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2074884T3 true ES2074884T3 (es) | 1995-09-16 |
Family
ID=24640618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92907045T Expired - Lifetime ES2074884T3 (es) | 1991-02-20 | 1992-02-14 | Agentes neuroprotectores. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5508401A (es) |
EP (1) | EP0573548B1 (es) |
JP (1) | JPH06505737A (es) |
KR (1) | KR100199913B1 (es) |
AT (1) | ATE124946T1 (es) |
AU (1) | AU662730B2 (es) |
CA (1) | CA2101933A1 (es) |
DE (1) | DE69203445T2 (es) |
DK (1) | DK0573548T3 (es) |
ES (1) | ES2074884T3 (es) |
GR (1) | GR3017663T3 (es) |
IE (1) | IE69124B1 (es) |
NZ (1) | NZ241635A (es) |
PT (1) | PT100133B (es) |
WO (1) | WO1992014813A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT100431B (pt) * | 1991-04-29 | 1999-08-31 | Univ Oregon | Derivados do 5-(iminometano-10.11-di-hidro-5h-dibenzo{ a.d}ciclo-heptano que sao ligandos dos receptores de fenciclidina (pcp) e sua utilizacao |
JP2933554B2 (ja) * | 1996-11-28 | 1999-08-16 | 九州日本電気株式会社 | 半導体装置およびその製造方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3361767A (en) * | 1966-04-04 | 1968-01-02 | American Home Prod | 10, 5(epoxymethano)-10, 11-dihydro-5h-dibenzo[a, d]cyclohepten-13-one and derivatives |
US3597433A (en) * | 1968-08-19 | 1971-08-03 | Ayerst Mckenna & Harrison | 10,11 - dihydro - 5,10 - (iminomethano)-5h-dibenzo(a,d)cycloheptene and derivatives thereof |
US5011834A (en) * | 1989-04-14 | 1991-04-30 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | PCP receptor ligands and the use thereof |
US4940789A (en) * | 1989-10-10 | 1990-07-10 | American Home Products Corporation | 10,11-dihydro-5-alkyl-12-substituted-10,5-(iminomethano)-5H-dibenzo[a,d]cycloheptenes as neuroprotectant agents |
PT100431B (pt) * | 1991-04-29 | 1999-08-31 | Univ Oregon | Derivados do 5-(iminometano-10.11-di-hidro-5h-dibenzo{ a.d}ciclo-heptano que sao ligandos dos receptores de fenciclidina (pcp) e sua utilizacao |
-
1991
- 1991-02-20 US US07/658,283 patent/US5508401A/en not_active Expired - Lifetime
-
1992
- 1992-02-14 DK DK92907045.6T patent/DK0573548T3/da active
- 1992-02-14 WO PCT/US1992/001204 patent/WO1992014813A1/en active IP Right Grant
- 1992-02-14 AT AT92907045T patent/ATE124946T1/de not_active IP Right Cessation
- 1992-02-14 EP EP92907045A patent/EP0573548B1/en not_active Expired - Lifetime
- 1992-02-14 CA CA002101933A patent/CA2101933A1/en not_active Abandoned
- 1992-02-14 ES ES92907045T patent/ES2074884T3/es not_active Expired - Lifetime
- 1992-02-14 KR KR1019930702470A patent/KR100199913B1/ko not_active IP Right Cessation
- 1992-02-14 AU AU14430/92A patent/AU662730B2/en not_active Ceased
- 1992-02-14 DE DE69203445T patent/DE69203445T2/de not_active Expired - Fee Related
- 1992-02-14 JP JP4506772A patent/JPH06505737A/ja active Pending
- 1992-02-18 IE IE920513A patent/IE69124B1/en not_active IP Right Cessation
- 1992-02-18 PT PT100133A patent/PT100133B/pt not_active IP Right Cessation
- 1992-02-18 NZ NZ241635A patent/NZ241635A/en unknown
-
1995
- 1995-10-05 GR GR950402768T patent/GR3017663T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2101933A1 (en) | 1992-08-21 |
DK0573548T3 (da) | 1995-11-13 |
AU1443092A (en) | 1992-09-15 |
DE69203445D1 (de) | 1995-08-17 |
JPH06505737A (ja) | 1994-06-30 |
GR3017663T3 (en) | 1996-01-31 |
IE69124B1 (en) | 1996-08-07 |
PT100133B (pt) | 1999-06-30 |
NZ241635A (en) | 1993-10-26 |
AU662730B2 (en) | 1995-09-14 |
US5508401A (en) | 1996-04-16 |
WO1992014813A1 (en) | 1992-09-03 |
KR100199913B1 (ko) | 1999-06-15 |
KR930703318A (ko) | 1993-11-29 |
EP0573548B1 (en) | 1995-07-12 |
EP0573548A1 (en) | 1993-12-15 |
IE920513A1 (en) | 1992-08-26 |
PT100133A (pt) | 1993-05-31 |
DE69203445T2 (de) | 1995-11-23 |
ATE124946T1 (de) | 1995-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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