ES2104370T3 - Derivados de (arilalquilaminobencil)aminopropionamidas sustituidas, su preparacion y utilizacion. - Google Patents
Derivados de (arilalquilaminobencil)aminopropionamidas sustituidas, su preparacion y utilizacion.Info
- Publication number
- ES2104370T3 ES2104370T3 ES94911181T ES94911181T ES2104370T3 ES 2104370 T3 ES2104370 T3 ES 2104370T3 ES 94911181 T ES94911181 T ES 94911181T ES 94911181 T ES94911181 T ES 94911181T ES 2104370 T3 ES2104370 T3 ES 2104370T3
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- arylalkylaminobencil
- aminopropionamides
- derivatives
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
EN LA INVENCION SE PRESENTAN NUEVOS COMPUESTOS DE LA FORMULA (I) EN LA QUE N ES UN ENTERO DE 1 A 4; CADA R Y R1, QUE PUEDEN SER IGUALES O DIFERENTES, ES HIDROGENO, HALOGENO, TRIFLUOMETILO O ALCOXI C1-C4; R2 ES HIDROGENO O ALQUILO C1-C4; Y UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS; Y EN LA QUE CUANDO, R ES HIDROGENO, R1 ES HIDROGENO O HALOGENO Y N ES UNO, AL MISMO TIEMPO, ENTONCES R2 ES DISTINTO DE HIDROGENO O METILO; Y DE LA FORMULA (IA) EN LA QUE R3 ES HALOGENO, Y UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS, QUE SON ACTIVOS EN EL SISTEMA NERVIOSO CENTRAL (CNS) Y SE PUEDEN UTILIZAR EN METODOS DE TERAPIA COMO AGENTES ANTIEPILEPTICOS, ANTI-PARKINSON, NEUROPROTECTORES, ANTIDEPRESIVOS, ANTIESPASTICOS E HIPNOTICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939306899A GB9306899D0 (en) | 1993-04-01 | 1993-04-01 | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2104370T3 true ES2104370T3 (es) | 1997-10-01 |
Family
ID=10733226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94911181T Expired - Lifetime ES2104370T3 (es) | 1993-04-01 | 1994-03-15 | Derivados de (arilalquilaminobencil)aminopropionamidas sustituidas, su preparacion y utilizacion. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5449692A (es) |
EP (1) | EP0648202B1 (es) |
JP (1) | JP3542600B2 (es) |
KR (1) | KR950701905A (es) |
CN (1) | CN1035939C (es) |
AT (1) | ATE152442T1 (es) |
AU (1) | AU667169B2 (es) |
CA (1) | CA2136008C (es) |
DE (1) | DE69402935T2 (es) |
DK (1) | DK0648202T3 (es) |
ES (1) | ES2104370T3 (es) |
FI (1) | FI945582A (es) |
GB (1) | GB9306899D0 (es) |
GR (1) | GR3024150T3 (es) |
HU (1) | HUT70944A (es) |
IL (1) | IL108970A0 (es) |
NZ (1) | NZ263183A (es) |
PL (1) | PL306538A1 (es) |
RU (1) | RU94046144A (es) |
WO (1) | WO1994022809A1 (es) |
ZA (1) | ZA941964B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9515412D0 (en) * | 1995-07-27 | 1995-09-27 | Pharmacia Spa | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives |
IT1283489B1 (it) * | 1996-07-23 | 1998-04-21 | Chiesi Farma Spa | Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico |
CA2310664C (en) * | 1997-11-21 | 2008-03-11 | Euro-Celtique S.A. | Substituted 2-aminoacetamides and the use thereof |
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
US6281211B1 (en) | 1999-02-04 | 2001-08-28 | Euro-Celtique S.A. | Substituted semicarbazides and the use thereof |
DK1169060T3 (da) * | 1999-04-09 | 2006-01-16 | Euro Celtique Sa | Natriumkanalblokkerpræparater og anvendelse deraf |
MXPA04002009A (es) | 2001-09-03 | 2004-07-08 | Newron Pharm Spa | Composicion farmaceutica que comprende gabapentina o un analogo de la misma y alfa-aminoamida y su uso como analgesico. |
EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
KR101277520B1 (ko) * | 2004-09-10 | 2013-06-21 | 뉴론 파마슈티칼즈 에스. 피. 에이. | (할로벤질옥시)벤질아미노-프로판아미드를 포함하는 선택적 나트륨 및/또는 칼슘 채널 조절제로서 유용한 약제학적 조성물 |
AR057982A1 (es) * | 2005-10-26 | 2008-01-09 | Boehringer Ingelheim Int | Compuestos de [hetero) arilo con actividad antagonista de mch y composicion farmaceutica que comprende estos compuestos |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1140748A (en) * | 1966-06-23 | 1969-01-22 | Ici Ltd | New carboxylic acid derivatives |
US4049663A (en) * | 1972-06-06 | 1977-09-20 | Allen & Hanburys Limited | Ethylene diamine derivatives |
DE3050800C2 (es) * | 1979-03-22 | 1989-06-22 | Continental Pharma Inc., Bruessel/Bruxelles, Be | |
FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
US4728668A (en) * | 1985-04-16 | 1988-03-01 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4725619A (en) * | 1985-04-16 | 1988-02-16 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4631287A (en) * | 1985-04-16 | 1986-12-23 | Usv Pharmaceutical Corp. | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
IL94466A (en) * | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
-
1993
- 1993-04-01 GB GB939306899A patent/GB9306899D0/en active Pending
-
1994
- 1994-03-14 IL IL10897094A patent/IL108970A0/xx not_active IP Right Cessation
- 1994-03-15 HU HU9403809A patent/HUT70944A/hu unknown
- 1994-03-15 WO PCT/EP1994/000825 patent/WO1994022809A1/en active IP Right Grant
- 1994-03-15 PL PL94306538A patent/PL306538A1/xx unknown
- 1994-03-15 EP EP94911181A patent/EP0648202B1/en not_active Expired - Lifetime
- 1994-03-15 RU RU94046144/04A patent/RU94046144A/ru unknown
- 1994-03-15 CA CA002136008A patent/CA2136008C/en not_active Expired - Fee Related
- 1994-03-15 ES ES94911181T patent/ES2104370T3/es not_active Expired - Lifetime
- 1994-03-15 NZ NZ263183A patent/NZ263183A/en unknown
- 1994-03-15 KR KR1019940704344A patent/KR950701905A/ko not_active Application Discontinuation
- 1994-03-15 DE DE69402935T patent/DE69402935T2/de not_active Expired - Fee Related
- 1994-03-15 AU AU63776/94A patent/AU667169B2/en not_active Ceased
- 1994-03-15 DK DK94911181.9T patent/DK0648202T3/da active
- 1994-03-15 CN CN94190169A patent/CN1035939C/zh not_active Expired - Fee Related
- 1994-03-15 AT AT94911181T patent/ATE152442T1/de not_active IP Right Cessation
- 1994-03-15 JP JP52143094A patent/JP3542600B2/ja not_active Expired - Fee Related
- 1994-03-21 ZA ZA941964A patent/ZA941964B/xx unknown
- 1994-03-22 US US08/215,694 patent/US5449692A/en not_active Expired - Lifetime
- 1994-11-28 FI FI945582A patent/FI945582A/fi unknown
-
1997
- 1997-07-16 GR GR970401800T patent/GR3024150T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH08504828A (ja) | 1996-05-28 |
RU94046144A (ru) | 1996-09-27 |
DK0648202T3 (da) | 1997-10-27 |
CA2136008C (en) | 2005-06-14 |
IL108970A0 (en) | 1994-06-24 |
EP0648202B1 (en) | 1997-05-02 |
ZA941964B (en) | 1994-10-19 |
PL306538A1 (en) | 1995-04-03 |
HU9403809D0 (en) | 1995-02-28 |
ATE152442T1 (de) | 1997-05-15 |
DE69402935D1 (de) | 1997-06-05 |
FI945582A0 (fi) | 1994-11-28 |
AU6377694A (en) | 1994-10-24 |
EP0648202A1 (en) | 1995-04-19 |
CN1035939C (zh) | 1997-09-24 |
CA2136008A1 (en) | 1994-10-13 |
AU667169B2 (en) | 1996-03-07 |
CN1104018A (zh) | 1995-06-21 |
KR950701905A (ko) | 1995-05-17 |
GB9306899D0 (en) | 1993-05-26 |
HUT70944A (en) | 1995-11-28 |
GR3024150T3 (en) | 1997-10-31 |
NZ263183A (en) | 1996-02-27 |
DE69402935T2 (de) | 1997-11-20 |
US5449692A (en) | 1995-09-12 |
FI945582A (fi) | 1994-11-28 |
WO1994022809A1 (en) | 1994-10-13 |
JP3542600B2 (ja) | 2004-07-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO306237B1 (no) | Anvendelse av xantinderivater som antidepressive midler | |
FI961914A (fi) | Lyhytvaikutteiset dihydropyridiinit | |
ES2122253T3 (es) | Derivados (arilalcoxibencil)aminopropanamidicos sustituidos, su preparacion y su utilizacion como agentes antiepilepticos, neuroprotectores y antidepresivos. | |
ES2105286T3 (es) | Derivados de etanolamina que tienen actividades simpatomimetica y anti-polaquiuria. | |
ES2104370T3 (es) | Derivados de (arilalquilaminobencil)aminopropionamidas sustituidas, su preparacion y utilizacion. | |
ATE17346T1 (de) | Benzamido-derivate. | |
ES2124256T3 (es) | Arilmorfolina, preparacion y uso. | |
DE69330601D1 (de) | Serotoninergische ergolin derivate | |
DK0581904T3 (da) | Fremgangsmåde til inhibering af fibrose | |
TW429147B (en) | Pharmaceutical composition for the treatment of CNS disorders | |
IE802682L (en) | Oxazoline derivatives | |
DK0651747T3 (da) | Carbostyrilderivater |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 648202 Country of ref document: ES |