ATE303162T1 - Natrium kanalblocker zusammensetzungen und deren verwendung - Google Patents
Natrium kanalblocker zusammensetzungen und deren verwendungInfo
- Publication number
- ATE303162T1 ATE303162T1 AT00923183T AT00923183T ATE303162T1 AT E303162 T1 ATE303162 T1 AT E303162T1 AT 00923183 T AT00923183 T AT 00923183T AT 00923183 T AT00923183 T AT 00923183T AT E303162 T1 ATE303162 T1 AT E303162T1
- Authority
- AT
- Austria
- Prior art keywords
- sodium channel
- channel blocking
- blocking compositions
- convulsion
- disclosed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12854399P | 1999-04-09 | 1999-04-09 | |
PCT/US2000/009387 WO2000061188A1 (en) | 1999-04-09 | 2000-04-10 | Sodium channel blocker compositions and the use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE303162T1 true ATE303162T1 (de) | 2005-09-15 |
Family
ID=22435837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00923183T ATE303162T1 (de) | 1999-04-09 | 2000-04-10 | Natrium kanalblocker zusammensetzungen und deren verwendung |
Country Status (9)
Country | Link |
---|---|
US (3) | US20020037926A1 (de) |
EP (1) | EP1169060B1 (de) |
JP (1) | JP2002541215A (de) |
AT (1) | ATE303162T1 (de) |
AU (1) | AU4334900A (de) |
CA (1) | CA2370030C (de) |
DE (1) | DE60022333T2 (de) |
DK (1) | DK1169060T3 (de) |
WO (1) | WO2000061188A1 (de) |
Families Citing this family (59)
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WO2000061188A1 (en) * | 1999-04-09 | 2000-10-19 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
US7164034B2 (en) * | 1999-06-10 | 2007-01-16 | Pfizer Inc. | Alpha2delta ligands for fibromyalgia and other disorders |
US20080207755A1 (en) * | 2000-05-31 | 2008-08-28 | Pfizer Inc | Alpha 2 Delta Ligands For Fibromyalgia and Other Disorders |
PT1423168E (pt) | 2001-09-03 | 2006-05-31 | Newron Pharm Spa | Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico |
US20030124174A1 (en) * | 2001-10-25 | 2003-07-03 | Endo Pharmaceuticals, Inc | Method for treating non-neuropathic pain |
BRPI0200751B1 (pt) * | 2002-02-06 | 2018-10-23 | Univ Minas Gerais | complexos de inclusão de benzaldeído semicabazona em ciclodextrinas e seu método de preparação |
WO2003072751A2 (en) | 2002-02-25 | 2003-09-04 | Vanderbilt University | Expression system for human brain-specific voltage-gated sodium channel, type 1 |
PL377520A1 (pl) * | 2002-12-13 | 2006-02-06 | Warner-Lambert Company Llc | Pochodne pregabaliny przeznaczone do leczenia fibromialgii i innych zaburzeń |
EP1438956A1 (de) * | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind |
DE10332487A1 (de) * | 2003-07-16 | 2005-02-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen |
DE10359335A1 (de) * | 2003-10-23 | 2005-05-25 | Viatris Gmbh & Co. Kg | Kombinationen aus Kaliumkanalöffnern und Natriumkanalinhibitoren oder Natriumkanal beeinflussenden Wirkstoffen zur Behandlung von Schmerzzuständen |
US20050112183A1 (en) * | 2003-11-25 | 2005-05-26 | Galer Bradley S. | Compositions and methods for treating neuropathic sensory loss |
US20050209319A1 (en) * | 2004-03-18 | 2005-09-22 | Xenoport, Inc. | Treatment of local pain |
ITMI20041447A1 (it) * | 2004-07-20 | 2004-10-20 | Zambon Spa | Composizione farmaceutica comprendente gabapentina |
US8410149B2 (en) | 2004-12-06 | 2013-04-02 | Siga Technologies Inc. | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses |
US7994221B2 (en) | 2004-12-06 | 2011-08-09 | Siga Technologies, Inc. | Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses |
JP5285276B2 (ja) | 2004-12-06 | 2013-09-11 | シガ テクノロジーズ,インコーポレーテッド | アレナウイルスに関連した感染をはじめとする出血熱ウイルスを処置するための、スルホニルセミカルバジド、セミカルバジドおよび尿素、その医薬組成物および方法 |
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GB0603008D0 (en) * | 2006-02-14 | 2006-03-29 | Portela & Ca Sa | Method |
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GB0700773D0 (en) | 2007-01-15 | 2007-02-21 | Portela & Ca Sa | Drug therapies |
CN101034257B (zh) * | 2007-04-06 | 2010-09-08 | 上海复旦天臣新技术有限公司 | 用于全息记录的感光薄膜及其制备方法 |
US20100249238A1 (en) * | 2007-07-02 | 2010-09-30 | Ruben Dario Sinisterra | Pharmaceutical compositions comprising semicarbazones and thiosemicarbazones and method for treating inflammatory, painful and febrile conditions and preventing signs and symptoms of inflammation |
CN104958282B (zh) * | 2007-11-23 | 2018-05-29 | 格吕伦塔尔有限公司 | 他喷他多组合物 |
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CN102892454B (zh) * | 2010-01-26 | 2016-01-20 | 迈克尔·A·埃文斯 | 用于去神经支配的方法、装置以及药剂 |
US9120752B2 (en) | 2010-07-16 | 2015-09-01 | Purdue Pharma, L.P. | Pyridine compounds as sodium channel blockers |
US9056832B2 (en) | 2010-09-17 | 2015-06-16 | Purdue Pharma L.P. | Pyridine compounds and the users thereof |
WO2012046132A1 (en) | 2010-10-05 | 2012-04-12 | Purdue Pharma L.P. | Quinazoline compounds as sodium channel blockers |
US20130189354A1 (en) * | 2010-10-07 | 2013-07-25 | Trinity Laboratories, Inc., | Novel Pharmaceutical Compositions for Treating Chronic Pain and Pain Associated with Neuropathy |
WO2012085650A1 (en) | 2010-12-22 | 2012-06-28 | Purdue Pharma L.P. | Substituted pyridines as sodium channel blockers |
ME02873B (de) | 2011-09-02 | 2018-04-20 | Purdue Pharma Lp | Pyrimidine als natriumkanalblocker |
WO2013064883A1 (en) | 2011-10-31 | 2013-05-10 | Purdue Pharma L.P. | Heteroaryl compounds as sodium channel blockers |
WO2013064884A1 (en) | 2011-10-31 | 2013-05-10 | Purdue Pharma L.P. | Quaternized amines as sodium channel blockers |
US9133131B2 (en) | 2011-11-15 | 2015-09-15 | Purdue Pharma L.P. | Pyrimidine diol amides as sodium channel blockers |
AU2013203824A1 (en) | 2012-03-16 | 2013-10-03 | Purdue Pharma L.P. | Substituted pyridines and pryimidines as sodium channel blockers |
US9714252B2 (en) | 2012-12-20 | 2017-07-25 | Purdue Pharma L.P. | Cyclic sulfonamides as sodium channel blockers |
WO2014112152A1 (ja) | 2013-01-18 | 2014-07-24 | 有限会社ケムフィズ | 神経因性疾病の治療のための医薬 |
US9120786B2 (en) | 2013-03-04 | 2015-09-01 | Purdue Pharma, L.P. | Triazine carboxamides as sodium channel blockers |
WO2014135955A1 (en) | 2013-03-04 | 2014-09-12 | Purdue Pharma L.P. | Pyrimidine carboxamides as sodium channel blockers |
AU2014235063B2 (en) | 2013-03-15 | 2017-05-04 | Purdue Pharma L.P. | Carboxamide derivatives and use thereof |
US9359330B2 (en) | 2013-08-26 | 2016-06-07 | Purdue Pharma L.P. | Substituted piperidines as sodium channel blockers |
CN105612152A (zh) | 2013-08-26 | 2016-05-25 | 普渡制药公司 | 氮杂螺[4.5]癸烷衍生物及其用途 |
US9828348B2 (en) | 2013-11-08 | 2017-11-28 | Purdue Pharma L.P. | Benzimidazole derivatives and use thereof |
US9340504B2 (en) | 2013-11-21 | 2016-05-17 | Purdue Pharma L.P. | Pyridine and piperidine derivatives as novel sodium channel blockers |
WO2015094443A1 (en) | 2013-12-20 | 2015-06-25 | Purdue Pharma L.P. | Pyrimidines and use thereof |
US9695144B2 (en) | 2013-12-23 | 2017-07-04 | Purdue Pharma L.P. | Dibenzazepine derivatives and use thereof |
AU2014370407B2 (en) | 2013-12-23 | 2018-03-29 | Purdue Pharma L.P. | Indazoles and use thereof |
EP3089978B1 (de) | 2013-12-30 | 2018-08-29 | Purdue Pharma L.P. | Pyridonsulfonmorphinan-analoga als opioidrezeptorliganden |
JP6526023B2 (ja) | 2014-01-24 | 2019-06-05 | パーデュー、ファーマ、リミテッド、パートナーシップ | ピリジン類及びピリミジン類並びにその使用 |
CA2939501C (en) | 2014-02-12 | 2020-07-07 | Purdue Pharma L.P. | Isoquinoline derivatives and use thereof |
US10730866B2 (en) | 2014-04-07 | 2020-08-04 | Purdue Pharma L.P. | Indole derivatives and use thereof |
WO2015171553A1 (en) | 2014-05-06 | 2015-11-12 | Purdue Pharma L.P. | Benzomorphan analogs and use thereof |
CA2952124A1 (en) | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Heterocyclic morphinan derivatives and use thereof |
JP6360915B2 (ja) | 2014-06-13 | 2018-07-18 | パーデュー、ファーマ、リミテッド、パートナーシップ | アザモルフィナン誘導体及びその使用 |
WO2018125716A1 (en) | 2017-01-02 | 2018-07-05 | Purdue Pharma L.P. | Morphinan derivatives and use thereof |
JP2024509372A (ja) * | 2021-02-26 | 2024-03-01 | ヴァイルマ インコーポレイテッド | ガバペンチノイドの局所投与のための方法及び製剤 |
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WO2000061188A1 (en) * | 1999-04-09 | 2000-10-19 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
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PT1423168E (pt) | 2001-09-03 | 2006-05-31 | Newron Pharm Spa | Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico |
-
2000
- 2000-04-10 WO PCT/US2000/009387 patent/WO2000061188A1/en active IP Right Grant
- 2000-04-10 JP JP2000610520A patent/JP2002541215A/ja active Pending
- 2000-04-10 DE DE60022333T patent/DE60022333T2/de not_active Expired - Lifetime
- 2000-04-10 AU AU43349/00A patent/AU4334900A/en not_active Abandoned
- 2000-04-10 AT AT00923183T patent/ATE303162T1/de active
- 2000-04-10 DK DK00923183T patent/DK1169060T3/da active
- 2000-04-10 CA CA002370030A patent/CA2370030C/en not_active Expired - Fee Related
- 2000-04-10 EP EP00923183A patent/EP1169060B1/de not_active Expired - Lifetime
-
2001
- 2001-10-05 US US09/971,007 patent/US20020037926A1/en not_active Abandoned
-
2003
- 2003-08-21 US US10/644,783 patent/US7393872B2/en not_active Expired - Lifetime
-
2008
- 2008-06-13 US US12/138,568 patent/US20080318932A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20020037926A1 (en) | 2002-03-28 |
US7393872B2 (en) | 2008-07-01 |
WO2000061188A1 (en) | 2000-10-19 |
US20040054005A1 (en) | 2004-03-18 |
JP2002541215A (ja) | 2002-12-03 |
US20080318932A1 (en) | 2008-12-25 |
EP1169060A1 (de) | 2002-01-09 |
DE60022333D1 (de) | 2005-10-06 |
CA2370030A1 (en) | 2000-10-19 |
CA2370030C (en) | 2007-08-14 |
DE60022333T2 (de) | 2006-07-06 |
WO2000061188A9 (en) | 2002-02-14 |
DK1169060T3 (da) | 2006-01-16 |
AU4334900A (en) | 2000-11-14 |
EP1169060B1 (de) | 2005-08-31 |
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