NO960371L - Piperazinderivater som ter - Google Patents

Piperazinderivater som ter

Info

Publication number
NO960371L
NO960371L NO960371A NO960371A NO960371L NO 960371 L NO960371 L NO 960371L NO 960371 A NO960371 A NO 960371A NO 960371 A NO960371 A NO 960371A NO 960371 L NO960371 L NO 960371L
Authority
NO
Norway
Prior art keywords
group
compounds
ter
piperazine derivatives
sonh
Prior art date
Application number
NO960371A
Other languages
English (en)
Norwegian (no)
Other versions
NO960371D0 (no
Inventor
Amedeo Leonardi
Carlo Riva
Gianni Motta
Rodolfo Testa
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of NO960371D0 publication Critical patent/NO960371D0/no
Publication of NO960371L publication Critical patent/NO960371L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
NO960371A 1993-07-30 1996-01-29 Piperazinderivater som ter NO960371L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93MI001717A IT1266582B1 (it) 1993-07-30 1993-07-30 Derivati (di)azacicloesanici e diazacicloeptanici
PCT/EP1994/002437 WO1995004049A1 (en) 1993-07-30 1994-07-22 PIPERAZINE DERIVATIVES AS α1A-ADRENERGIC RECEPTOR ANTAGONISTS

Publications (2)

Publication Number Publication Date
NO960371D0 NO960371D0 (no) 1996-01-29
NO960371L true NO960371L (no) 1996-03-29

Family

ID=11366733

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960371A NO960371L (no) 1993-07-30 1996-01-29 Piperazinderivater som ter

Country Status (14)

Country Link
EP (1) EP0711288A1 (it)
JP (1) JPH09500883A (it)
KR (1) KR960703884A (it)
CN (1) CN1132508A (it)
AU (1) AU680037B2 (it)
CA (1) CA2168443A1 (it)
IL (1) IL110348A0 (it)
IT (1) IT1266582B1 (it)
MX (1) MXPA94005805A (it)
NO (1) NO960371L (it)
NZ (1) NZ271634A (it)
SG (1) SG46281A1 (it)
WO (1) WO1995004049A1 (it)
ZA (1) ZA945625B (it)

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US5620993A (en) * 1995-06-07 1997-04-15 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
US5661163A (en) * 1995-06-07 1997-08-26 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
US5659033A (en) * 1995-09-13 1997-08-19 Neurogen Corporation N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands
US5807856A (en) * 1995-11-15 1998-09-15 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonist
BR9611487A (pt) * 1995-11-17 1999-01-19 Warner Lambert Co Inibidores de sulfonamida de metaloproteinases de matriz
JP4327249B2 (ja) * 1995-12-29 2009-09-09 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 抗ヘルペスウイルス性を有するフェニルチアゾール誘導体
US6288091B1 (en) 1995-12-29 2001-09-11 Boehringer Ingelheim Ltd. Antiherpes virus compounds and methods for their preparation and use
EP0891344B1 (fr) * 1996-04-05 2002-12-18 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Antagonistes du recepteur alpha-1 adrenergique
JP4150435B2 (ja) * 1996-04-18 2008-09-17 株式会社資生堂 アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤
EP1270571B1 (en) 1996-07-19 2006-09-06 Takeda Pharmaceutical Company Limited Heterocyclic compounds, their production and use
EP0984777B1 (en) * 1997-05-12 2003-09-17 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatement of benign prostatic hyperlasia
AU2002300904B2 (en) * 1997-05-12 2004-12-23 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
US6271234B1 (en) 1997-08-01 2001-08-07 Recordati S.A., Chemical And Pharmaceutical Company 1,4-disubstituted piperazines
IT1293804B1 (it) 1997-08-01 1999-03-10 Recordati Chem Pharm Diarilalchilpiperazine attive sulle basse vie urinarie
US6399614B1 (en) 1997-08-01 2002-06-04 Recordati S.A. Chemical And Pharmaceutical Company 1-(N-phenylaminoalkyl)piperazine derivatives substituted at position 2 of the phenyl ring
IT1293807B1 (it) * 1997-08-01 1999-03-10 Recordati Chem Pharm Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico
JP2001512110A (ja) * 1997-08-01 2001-08-21 レコルダチ エッセ.ア.,ケミカル アンド ファーマシューティカル カンパニー 1,4−ジ置換ピペラジン
ZA991315B (en) * 1998-02-20 2000-11-20 Ortho Mcneil Pharm Inc Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia.
ATE315033T1 (de) 1998-08-07 2006-02-15 Chiron Corp Subtituierte isoxazole derivate als estrogen rezeptor modulatore
IT1314191B1 (it) * 1999-10-18 2002-12-06 Recordati Chem Pharm Derivati isossazolcarbossamidici
US6365591B1 (en) 1999-10-18 2002-04-02 Recordati, S.A., Chemical And Pharmacueticals Company Isoxazolecarboxamide derivatives
AR027133A1 (es) * 1999-12-30 2003-03-12 Lundbeck & Co As H Derivados de heteroarilo, su preparacion y uso.
SE0004780D0 (sv) 2000-12-22 2000-12-22 Jordanian Pharmaceutical Mfg & Novel compunds
JP3940290B2 (ja) * 2000-12-22 2007-07-04 ザ・ヨルダニアン・フアーマシユーテイカル・エム・エフ・ジー・アンド・メデイカル・イクイツプメント・カンパニー・リミテツド 新規化合物
EP1351936A1 (en) * 2001-01-15 2003-10-15 Glaxo Group Limited Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression
US7153858B2 (en) 2003-01-31 2006-12-26 Epix Delaware, Inc. Arylpiperazinyl compounds
WO2008120235A1 (en) * 2007-03-30 2008-10-09 Council Of Scientific & Industrial Research Novel benzophenone hybrids as potential anticancer agents and a process for the preparation thereof
EP2520561B1 (en) 2007-06-08 2016-02-10 MannKind Corporation IRE-1A Inhibitors
MX2012014273A (es) 2010-06-07 2013-03-22 Novomedix Llc Compuestos furanilo y su uso.
ES2631607T3 (es) * 2011-12-09 2017-09-01 Research Triangle Institute, International 4-Arilpiperazinas 1-sustituidas como antagonistas del receptor opioide kappa
BR102012000187A2 (pt) * 2012-01-05 2018-04-10 Univ Rio De Janeiro Derivados n-fenilpiperazínicos antagonistas de adrenoceptores a1a, a1d e de receptores 5-ht1a no tratamento da hiperplasia prostática benigna, composições farmacêuticas contendo os mesmos
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors

Family Cites Families (16)

* Cited by examiner, † Cited by third party
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US2997472A (en) * 1961-08-22 Certificate of correction
FR6452M (it) * 1967-03-10 1968-11-12
FR1543944A (fr) * 1967-03-10 1968-10-31 Bruneau & Cie Lab Dérivés amidés de l'acide salicylique et leur préparation
US3557107A (en) * 1967-05-01 1971-01-19 Shulton Inc Phenylpiperazinylalkyl alkoxy anthranilates
FR1537901A (fr) * 1967-07-19 1968-08-30 Bruneau & Cie Lab Dérivés amidés d'acides halogéno et nitro benzoïques et leur préparation
FR6924M (it) * 1967-10-18 1969-05-05
US3846430A (en) * 1968-01-12 1974-11-05 Bruneau & Cie Lab 1-(2-methoxy-phenyl)-4-{8 2-(4-fluoro-benzamido)-ethyl{9 -piperazine
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
US4642291A (en) * 1982-09-01 1987-02-10 Sloan-Kettering Institute For Cancer Research Cell surface antigens of human astrocytoma
JPS5955878A (ja) * 1982-09-24 1984-03-31 Chugai Pharmaceut Co Ltd 新規なフエニルピペラジン誘導体
JPS60169467A (ja) * 1984-02-10 1985-09-02 Chugai Pharmaceut Co Ltd 新規なフエニルピペラジン誘導体
JP2556722B2 (ja) * 1988-02-18 1996-11-20 興和株式会社 新規なスルホンアミド化合物
US4857644A (en) * 1988-06-09 1989-08-15 American Home Products Corporation Aryl sulfonopiperazines as anti-inflammatory agents
ES2027898A6 (es) * 1991-01-24 1992-06-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina.
EP0558245A1 (en) * 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors
SE9201138D0 (sv) * 1992-04-09 1992-04-09 Astra Ab Novel phthalimidoalkylpiperazines

Also Published As

Publication number Publication date
AU680037B2 (en) 1997-07-17
CA2168443A1 (en) 1995-02-09
IT1266582B1 (it) 1997-01-09
AU7532394A (en) 1995-02-28
MXPA94005805A (es) 2004-08-20
ZA945625B (en) 1995-03-07
JPH09500883A (ja) 1997-01-28
EP0711288A1 (en) 1996-05-15
NZ271634A (en) 1996-09-25
NO960371D0 (no) 1996-01-29
KR960703884A (ko) 1996-08-31
CN1132508A (zh) 1996-10-02
IL110348A0 (en) 1994-10-21
ITMI931717A0 (it) 1993-07-30
SG46281A1 (en) 1998-02-20
WO1995004049A1 (en) 1995-02-09
ITMI931717A1 (it) 1995-01-30

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