NO960371L - Piperazinderivater som ter - Google Patents
Piperazinderivater som terInfo
- Publication number
- NO960371L NO960371L NO960371A NO960371A NO960371L NO 960371 L NO960371 L NO 960371L NO 960371 A NO960371 A NO 960371A NO 960371 A NO960371 A NO 960371A NO 960371 L NO960371 L NO 960371L
- Authority
- NO
- Norway
- Prior art keywords
- group
- compounds
- ter
- piperazine derivatives
- sonh
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001717A IT1266582B1 (it) | 1993-07-30 | 1993-07-30 | Derivati (di)azacicloesanici e diazacicloeptanici |
PCT/EP1994/002437 WO1995004049A1 (en) | 1993-07-30 | 1994-07-22 | PIPERAZINE DERIVATIVES AS α1A-ADRENERGIC RECEPTOR ANTAGONISTS |
Publications (2)
Publication Number | Publication Date |
---|---|
NO960371D0 NO960371D0 (no) | 1996-01-29 |
NO960371L true NO960371L (no) | 1996-03-29 |
Family
ID=11366733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO960371A NO960371L (no) | 1993-07-30 | 1996-01-29 | Piperazinderivater som ter |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0711288A1 (it) |
JP (1) | JPH09500883A (it) |
KR (1) | KR960703884A (it) |
CN (1) | CN1132508A (it) |
AU (1) | AU680037B2 (it) |
CA (1) | CA2168443A1 (it) |
IL (1) | IL110348A0 (it) |
IT (1) | IT1266582B1 (it) |
MX (1) | MXPA94005805A (it) |
NO (1) | NO960371L (it) |
NZ (1) | NZ271634A (it) |
SG (1) | SG46281A1 (it) |
WO (1) | WO1995004049A1 (it) |
ZA (1) | ZA945625B (it) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5620993A (en) * | 1995-06-07 | 1997-04-15 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
US5661163A (en) * | 1995-06-07 | 1997-08-26 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
US5659033A (en) * | 1995-09-13 | 1997-08-19 | Neurogen Corporation | N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands |
US5807856A (en) * | 1995-11-15 | 1998-09-15 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonist |
BR9611487A (pt) * | 1995-11-17 | 1999-01-19 | Warner Lambert Co | Inibidores de sulfonamida de metaloproteinases de matriz |
JP4327249B2 (ja) * | 1995-12-29 | 2009-09-09 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 抗ヘルペスウイルス性を有するフェニルチアゾール誘導体 |
US6288091B1 (en) | 1995-12-29 | 2001-09-11 | Boehringer Ingelheim Ltd. | Antiherpes virus compounds and methods for their preparation and use |
EP0891344B1 (fr) * | 1996-04-05 | 2002-12-18 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Antagonistes du recepteur alpha-1 adrenergique |
JP4150435B2 (ja) * | 1996-04-18 | 2008-09-17 | 株式会社資生堂 | アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤 |
EP1270571B1 (en) | 1996-07-19 | 2006-09-06 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds, their production and use |
EP0984777B1 (en) * | 1997-05-12 | 2003-09-17 | Ortho-Mcneil Pharmaceutical, Inc. | Arylsubstituted piperazines useful in the treatement of benign prostatic hyperlasia |
AU2002300904B2 (en) * | 1997-05-12 | 2004-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia |
US6271234B1 (en) | 1997-08-01 | 2001-08-07 | Recordati S.A., Chemical And Pharmaceutical Company | 1,4-disubstituted piperazines |
IT1293804B1 (it) | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Diarilalchilpiperazine attive sulle basse vie urinarie |
US6399614B1 (en) | 1997-08-01 | 2002-06-04 | Recordati S.A. Chemical And Pharmaceutical Company | 1-(N-phenylaminoalkyl)piperazine derivatives substituted at position 2 of the phenyl ring |
IT1293807B1 (it) * | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico |
JP2001512110A (ja) * | 1997-08-01 | 2001-08-21 | レコルダチ エッセ.ア.,ケミカル アンド ファーマシューティカル カンパニー | 1,4−ジ置換ピペラジン |
ZA991315B (en) * | 1998-02-20 | 2000-11-20 | Ortho Mcneil Pharm Inc | Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia. |
ATE315033T1 (de) | 1998-08-07 | 2006-02-15 | Chiron Corp | Subtituierte isoxazole derivate als estrogen rezeptor modulatore |
IT1314191B1 (it) * | 1999-10-18 | 2002-12-06 | Recordati Chem Pharm | Derivati isossazolcarbossamidici |
US6365591B1 (en) | 1999-10-18 | 2002-04-02 | Recordati, S.A., Chemical And Pharmacueticals Company | Isoxazolecarboxamide derivatives |
AR027133A1 (es) * | 1999-12-30 | 2003-03-12 | Lundbeck & Co As H | Derivados de heteroarilo, su preparacion y uso. |
SE0004780D0 (sv) | 2000-12-22 | 2000-12-22 | Jordanian Pharmaceutical Mfg & | Novel compunds |
JP3940290B2 (ja) * | 2000-12-22 | 2007-07-04 | ザ・ヨルダニアン・フアーマシユーテイカル・エム・エフ・ジー・アンド・メデイカル・イクイツプメント・カンパニー・リミテツド | 新規化合物 |
EP1351936A1 (en) * | 2001-01-15 | 2003-10-15 | Glaxo Group Limited | Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression |
US7153858B2 (en) | 2003-01-31 | 2006-12-26 | Epix Delaware, Inc. | Arylpiperazinyl compounds |
WO2008120235A1 (en) * | 2007-03-30 | 2008-10-09 | Council Of Scientific & Industrial Research | Novel benzophenone hybrids as potential anticancer agents and a process for the preparation thereof |
EP2520561B1 (en) | 2007-06-08 | 2016-02-10 | MannKind Corporation | IRE-1A Inhibitors |
MX2012014273A (es) | 2010-06-07 | 2013-03-22 | Novomedix Llc | Compuestos furanilo y su uso. |
ES2631607T3 (es) * | 2011-12-09 | 2017-09-01 | Research Triangle Institute, International | 4-Arilpiperazinas 1-sustituidas como antagonistas del receptor opioide kappa |
BR102012000187A2 (pt) * | 2012-01-05 | 2018-04-10 | Univ Rio De Janeiro | Derivados n-fenilpiperazínicos antagonistas de adrenoceptores a1a, a1d e de receptores 5-ht1a no tratamento da hiperplasia prostática benigna, composições farmacêuticas contendo os mesmos |
WO2023044364A1 (en) | 2021-09-15 | 2023-03-23 | Enko Chem, Inc. | Protoporphyrinogen oxidase inhibitors |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2997472A (en) * | 1961-08-22 | Certificate of correction | ||
FR6452M (it) * | 1967-03-10 | 1968-11-12 | ||
FR1543944A (fr) * | 1967-03-10 | 1968-10-31 | Bruneau & Cie Lab | Dérivés amidés de l'acide salicylique et leur préparation |
US3557107A (en) * | 1967-05-01 | 1971-01-19 | Shulton Inc | Phenylpiperazinylalkyl alkoxy anthranilates |
FR1537901A (fr) * | 1967-07-19 | 1968-08-30 | Bruneau & Cie Lab | Dérivés amidés d'acides halogéno et nitro benzoïques et leur préparation |
FR6924M (it) * | 1967-10-18 | 1969-05-05 | ||
US3846430A (en) * | 1968-01-12 | 1974-11-05 | Bruneau & Cie Lab | 1-(2-methoxy-phenyl)-4-{8 2-(4-fluoro-benzamido)-ethyl{9 -piperazine |
NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
US4642291A (en) * | 1982-09-01 | 1987-02-10 | Sloan-Kettering Institute For Cancer Research | Cell surface antigens of human astrocytoma |
JPS5955878A (ja) * | 1982-09-24 | 1984-03-31 | Chugai Pharmaceut Co Ltd | 新規なフエニルピペラジン誘導体 |
JPS60169467A (ja) * | 1984-02-10 | 1985-09-02 | Chugai Pharmaceut Co Ltd | 新規なフエニルピペラジン誘導体 |
JP2556722B2 (ja) * | 1988-02-18 | 1996-11-20 | 興和株式会社 | 新規なスルホンアミド化合物 |
US4857644A (en) * | 1988-06-09 | 1989-08-15 | American Home Products Corporation | Aryl sulfonopiperazines as anti-inflammatory agents |
ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
EP0558245A1 (en) * | 1992-02-25 | 1993-09-01 | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY | Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors |
SE9201138D0 (sv) * | 1992-04-09 | 1992-04-09 | Astra Ab | Novel phthalimidoalkylpiperazines |
-
1993
- 1993-07-30 IT IT93MI001717A patent/IT1266582B1/it active IP Right Grant
-
1994
- 1994-07-18 IL IL11034894A patent/IL110348A0/xx unknown
- 1994-07-22 EP EP94925382A patent/EP0711288A1/en not_active Withdrawn
- 1994-07-22 KR KR1019960700460A patent/KR960703884A/ko not_active Application Discontinuation
- 1994-07-22 WO PCT/EP1994/002437 patent/WO1995004049A1/en not_active Application Discontinuation
- 1994-07-22 CN CN94193622A patent/CN1132508A/zh active Pending
- 1994-07-22 AU AU75323/94A patent/AU680037B2/en not_active Ceased
- 1994-07-22 NZ NZ271634A patent/NZ271634A/en unknown
- 1994-07-22 CA CA002168443A patent/CA2168443A1/en not_active Abandoned
- 1994-07-22 SG SG1996002067A patent/SG46281A1/en unknown
- 1994-07-22 JP JP7505546A patent/JPH09500883A/ja active Pending
- 1994-07-29 MX MXPA94005805A patent/MXPA94005805A/es unknown
- 1994-07-29 ZA ZA945625A patent/ZA945625B/xx unknown
-
1996
- 1996-01-29 NO NO960371A patent/NO960371L/no unknown
Also Published As
Publication number | Publication date |
---|---|
AU680037B2 (en) | 1997-07-17 |
CA2168443A1 (en) | 1995-02-09 |
IT1266582B1 (it) | 1997-01-09 |
AU7532394A (en) | 1995-02-28 |
MXPA94005805A (es) | 2004-08-20 |
ZA945625B (en) | 1995-03-07 |
JPH09500883A (ja) | 1997-01-28 |
EP0711288A1 (en) | 1996-05-15 |
NZ271634A (en) | 1996-09-25 |
NO960371D0 (no) | 1996-01-29 |
KR960703884A (ko) | 1996-08-31 |
CN1132508A (zh) | 1996-10-02 |
IL110348A0 (en) | 1994-10-21 |
ITMI931717A0 (it) | 1993-07-30 |
SG46281A1 (en) | 1998-02-20 |
WO1995004049A1 (en) | 1995-02-09 |
ITMI931717A1 (it) | 1995-01-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO960371L (no) | Piperazinderivater som ter | |
ES2187660T3 (es) | Derivados de rapamicina. | |
KR20010006390A (ko) | 삼환식 화합물 | |
WO2000004014A1 (fr) | Derives de pyrimidine manifestant une activite antitumorale | |
NO943140L (no) | Heterobicykliske forbindelser | |
EP1070714A4 (en) | Amidine CONNECTIONS | |
NO982606D0 (no) | Naftylsubstituerte benzimidazolderivater som antikoagulanter | |
RU97114956A (ru) | Способ ингибирования межклеточной адгезии и способ ингибирования воспалительного процесса | |
CA2124680A1 (en) | Piperazine derivatives as 5-ht1a antagonists | |
DK0429627T3 (da) | Derivater af quinolin-3-carboxanilider | |
NO984939L (no) | Azetidinon-derivater for behandling av atherosklerose | |
TR199700206A2 (xx) | Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�. | |
HRP20000585B1 (en) | Substituted bisindolymaleimides for the inhibition of cell proliferation | |
HUP0302961A2 (hu) | (Aminoalkoxibenzoil) benzofuránok vagy benzotiofének, eljárás ilyen vegyületek előállítására és ilyen vegyületeket tartalmazó készítmények | |
DE50003989D1 (de) | Benzophenone und ihre verwendung als photoinitiatoren | |
ATE163410T1 (de) | Beta-oxo-beta-benzenepropanthioamidderivate | |
DE69617226D1 (de) | Piperidinderivate. | |
ATE207471T1 (de) | Dibenzo-oxazepin- und dioxepin-derivate und ihre verwendung als antitumormittel | |
NO983453L (no) | Fremgangsmåte for ökning av sfinkterfunksjon | |
NO994104L (no) | 5-hydroksymetyl-2-aminotetraliner i form av kardiovaskulaere midler | |
NZ304988A (en) | 1-omega-(3,4-dihydro-2-naphthalenyl)alkyl] cyclic amine derivatives and their use | |
EP1197211A4 (en) | CANCER PREVENTION AND TREATMENT ACTIVE INGREDIENTS | |
EA200200462A1 (ru) | Производные 2-арилхинолина, их получение и терапевтическое применение | |
ATE265453T1 (de) | Diketopiperazinderivate als thrombininhibitoren | |
CA2202031A1 (en) | Condensed indan derivatives and salts thereof |