NO954212L - Apparat og fremgangsmåte for konsentrasjon og separasjon av partikler i et lukket område - Google Patents

Apparat og fremgangsmåte for konsentrasjon og separasjon av partikler i et lukket område

Info

Publication number
NO954212L
NO954212L NO954212A NO954212A NO954212L NO 954212 L NO954212 L NO 954212L NO 954212 A NO954212 A NO 954212A NO 954212 A NO954212 A NO 954212A NO 954212 L NO954212 L NO 954212L
Authority
NO
Norway
Prior art keywords
concentration
sensitive
cell
area
conditions
Prior art date
Application number
NO954212A
Other languages
English (en)
Other versions
NO954212D0 (no
Inventor
Billy W Minshall
Patrick M Maloney
Fred Mill
Shelly Heimfeld
Stanley Corpuz
Penny Thompson
Eric Peterson
Dale Kalamass
Michael D Emde
Original Assignee
Cellpro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellpro Inc filed Critical Cellpro Inc
Publication of NO954212D0 publication Critical patent/NO954212D0/no
Publication of NO954212L publication Critical patent/NO954212L/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/20—Accessories; Auxiliary operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N2001/1062—Sampling under constant temperature, pressure, or the like
    • G01N2001/1081—Storing samples under refrigeration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N2011/0046—In situ measurement during mixing process
    • G01N2011/0053—In situ measurement during mixing process using ergometry; measuring power consumption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1039—Micropipettes, e.g. microcapillary tubes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Oppfinnelsen angår en partikkelseparator for oppsamling og manipulering av målpartikler, for eksempel målceller i et lukket sterilt område. I ett område blir forhold med lukket sterilt område opprettholdt fra separasjon gjennom konsentrasjon og/eller kryobehandlingstrinn og/eller transfusjon. Bevaring av lukkede sterile forhold er oppnådd ved bruk av de samme integrert koplede kar for oppsam- ling og konsentrasjon og overføring via integrert koplede rer til et kar for kryopreservering og/eller transfusjon. I en utførelse kan en grad av celle- konsentrasjon oppnås, mens man opprettholder forhold med lukket område, ved å bruke en hulfiberanordning, fortrinnsvis i en linje mellom kolonnen og oppsam- lingen. I en annen utførelse, blir hulfiber- anordningen brukt istedenfor kolonnen for å oppnå cellevasking. I en utførelse er det et flertall ventiler som er følsomme for en dataprosessor for å styre banen for fluidum gjennom partikkelsepara- toren. Et flertall sensorer er anordnet for å frem- bringe sensorsignaler som indikerer fluidum som strømmer gjennom celleseparatoren. En peristaltisk pumpe er følsom for mikroprosessorenheten for å styre hastigheten og retningen av fluidum gjennom ': systemet. En røreplateenhet er følsom for signal fra dataprosessoren for styrbart å omrøre innholdet i celleseparatoren.
NO954212A 1993-04-23 1995-10-20 Apparat og fremgangsmåte for konsentrasjon og separasjon av partikler i et lukket område NO954212L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/052,784 US5672481A (en) 1991-10-23 1993-04-23 Apparatus and method for particle separation in a closed field
PCT/US1994/004422 WO1994025848A1 (en) 1993-04-23 1994-04-22 Apparatus and method for particle concentration and separation in a closed field

Publications (2)

Publication Number Publication Date
NO954212D0 NO954212D0 (no) 1995-10-20
NO954212L true NO954212L (no) 1995-12-22

Family

ID=21979867

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954212A NO954212L (no) 1993-04-23 1995-10-20 Apparat og fremgangsmåte for konsentrasjon og separasjon av partikler i et lukket område

Country Status (10)

Country Link
US (1) US5672481A (no)
EP (1) EP0746753A4 (no)
JP (1) JPH08509552A (no)
KR (1) KR960702105A (no)
AU (1) AU699784B2 (no)
CA (1) CA2160009A1 (no)
FI (1) FI955015A (no)
NO (1) NO954212L (no)
NZ (1) NZ265563A (no)
WO (1) WO1994025848A1 (no)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6120735A (en) * 1992-02-26 2000-09-19 The Ohio States University Fractional cell sorter
US7288195B2 (en) * 1999-05-28 2007-10-30 Bio/Data Corporation Method and apparatus for directly sampling a fluid for microfiltration
GB2352652A (en) * 1999-08-06 2001-02-07 Fsm Technologies Ltd Pre-treating hollow fibre membranes for micro-organism detection
US6837613B2 (en) * 2001-04-10 2005-01-04 Levtech, Inc. Sterile fluid pumping or mixing system and related method
US7762716B2 (en) * 2000-10-09 2010-07-27 Levtech, Inc. Mixing vessel with a fluid-agitating element supported by a roller bearing
WO2003028869A2 (en) * 2001-10-03 2003-04-10 Levtech, Inc. Mixing bag or vessel having a receiver for a fluid-agitating element
ES2287254T3 (es) 2001-02-05 2007-12-16 Millipore Corporation Deteccion de microorganismos.
DE10146371A1 (de) * 2001-09-20 2003-04-17 Georg S Wengler Verfahren zur Gewinnung menschlicher oder tierischer Stammzellen sowie Anlage zur Durchführung des Verfahrens
GB2387130A (en) 2002-04-04 2003-10-08 Fluid Technologies Plc Hollow fibre filter membrane unit with microorganism detector, and associated usage
EP1569510B1 (en) 2002-09-27 2011-11-02 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US7153021B2 (en) * 2003-03-28 2006-12-26 Hyclone Laboratories, Inc. Container systems for mixing fluids with a magnetic stir bar
DE10320870A1 (de) * 2003-05-09 2004-12-09 Evotec Technologies Gmbh Partikelinjektor für einen Zellsortierer
US7588722B2 (en) * 2003-06-25 2009-09-15 Gambro Lundia Ab Extracorporeal treatment device with automatic emptying of waste bag
US20090136982A1 (en) 2005-01-18 2009-05-28 Biocept, Inc. Cell separation using microchannel having patterned posts
US20060252087A1 (en) * 2005-01-18 2006-11-09 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
US8158410B2 (en) 2005-01-18 2012-04-17 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
EP1838442B1 (en) 2005-01-18 2013-09-11 Biocept, Inc. Cell separation using microchannel having patterned posts
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US7695956B2 (en) * 2006-01-12 2010-04-13 Biocept, Inc. Device for cell separation and analysis and method of using
EP2114554A1 (en) * 2007-02-21 2009-11-11 Levtech Inc. Roller bearing for a fluid-agitating element and associated vessel
US8177072B2 (en) * 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
US8277651B2 (en) 2009-03-13 2012-10-02 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
JP5607896B2 (ja) * 2009-05-12 2014-10-15 株式会社日立製作所 凍結保存方法、凍結デバイス、凍結保存システム
JP5503360B2 (ja) * 2010-01-15 2014-05-28 シスメックス株式会社 試料調製装置
JP2013531541A (ja) * 2010-07-06 2013-08-08 サイトネット，エルエルシー 閉鎖システムにおいて生体材料を処理する装置及び方法
WO2012141697A1 (en) * 2011-04-13 2012-10-18 Fenwal, Inc. Systems and methods for use and control of an automated separator with adsorption columns
ES2570804T3 (es) 2012-03-21 2016-05-20 Gambro Lundia Ab Suministro de solución de tratamiento en un aparato de tratamiento extracorpóreo de sangre
EP2695652A1 (de) * 2012-08-09 2014-02-12 F. Hoffmann-La Roche AG System zur Abtrennung von Plasma aus Vollblut
EP2695656A1 (de) 2012-08-09 2014-02-12 F. Hoffmann-La Roche AG Verfahren sowie eine Separationsvorrichtung zur Abtrennung eines Filtrats von einer Probenflüssigkeit
EP2695655A1 (de) 2012-08-09 2014-02-12 F. Hoffmann-La Roche AG Mehrteilige Vorrichtung zur Gewinnung von Plasma aus Vollblut
US10260036B2 (en) 2014-10-17 2019-04-16 Sani-Tech West, Inc. Mixing and filtering system and method
JP6457338B2 (ja) * 2015-05-28 2019-01-23 株式会社日立製作所 液体還流容器、細胞濃縮装置及び細胞濃縮システム
JP6230575B2 (ja) * 2015-08-11 2017-11-15 上田製袋株式会社 凍結保存用バッグ、および凍結保存用バッグに対する生体組織の封入方法
JP6805601B2 (ja) * 2016-07-25 2020-12-23 大日本印刷株式会社 凍結保存容器
EP4263793A1 (en) * 2020-12-15 2023-10-25 Global Life Sciences Solutions USA LLC Systems and methods for cell enrichment, isolation and formulation
WO2023171378A1 (ja) * 2022-03-07 2023-09-14 ソニーグループ株式会社 試料調製システム及び試料調製方法

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3115460A (en) * 1960-04-28 1963-12-24 Lab Tek Plastics Co Centrifuge container
US3299693A (en) * 1963-12-04 1967-01-24 Du Pont Gas chromatographic analysis control apparatus
US3347454A (en) * 1964-05-13 1967-10-17 Baxter Laboratories Inc Method and apparatus for the centrifugal washing of particles in a closed system
SE332906B (no) * 1969-08-11 1971-02-22 Aga Ab
US3645687A (en) * 1970-01-05 1972-02-29 Samuel T Nerenberg Immunodiffusion plate apparatus
JPS50107565A (no) * 1974-01-29 1975-08-25
US4162855A (en) * 1974-11-18 1979-07-31 Spectroderm International, Inc. Magnetic stirrer apparatus
US4004975A (en) * 1975-12-30 1977-01-25 The United States Of America As Represented By The Secretary Of The Navy Method of isolating and cryopreserving human white cells from whole blood
US4098456A (en) * 1977-03-29 1978-07-04 Baxter Travenol Laboratories, Inc. Centrifuge system having collapsible centrifuge bags
US4111199A (en) * 1977-03-31 1978-09-05 Isaac Djerassi Method of collecting transfusable granulocytes by gravity leukopheresis
US4146172A (en) * 1977-10-18 1979-03-27 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing system
US4285464A (en) * 1979-01-22 1981-08-25 Haemonetics Corporation Apparatus for separation of blood into components thereof
US4223672A (en) * 1979-02-08 1980-09-23 Baxter Travenol Laboratories, Inc. Variable volume plasma treatment chamber for an apparatus for the extracorporeal treatment of disease
US4413772A (en) * 1979-09-10 1983-11-08 E. I. Du Pont De Nemours And Company Apparatus for centrifugal separation
US4619639A (en) * 1980-02-05 1986-10-28 Asahi Medical Co., Ltd. Method and apparatus for low pressure filtration of plasma from blood
US4316576A (en) * 1980-11-06 1982-02-23 Baxter Travenol Laboratories, Inc. Method and chamber for separating granulocytes from whole blood
US4512763A (en) * 1981-05-04 1985-04-23 Gamma Medical Products, Inc. Method and apparatus for selective removal of constituents of blood
US4439177A (en) * 1981-10-26 1984-03-27 Beckman Instruments, Inc. Rotor bucket liner
US4531932A (en) * 1981-11-27 1985-07-30 Dideco S.P.A. Centrifugal plasmapheresis device
US4482342A (en) * 1982-06-17 1984-11-13 Haemonetics Corporation Blood processing system for cell washing
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
US4610846A (en) * 1983-08-18 1986-09-09 Hans Martin Compartmentalized centrifugation chamber
US4880425A (en) * 1984-06-08 1989-11-14 Miles Laboratories, Inc. Blood bag having label providing enhanced gas transmissibility
EP0177718B1 (de) * 1984-09-11 1989-12-06 Partec AG Verfahren und Vorrichtung zur Sortierung von mikroskopischen Partikeln
US4675286A (en) * 1985-01-28 1987-06-23 Aspen Diagnostics, Inc. Fetal cell separation and testing
JPH0348517Y2 (no) * 1985-02-07 1991-10-16
US4807676A (en) * 1985-02-26 1989-02-28 Baxter International Inc. Fluid transfer workstation
JPS61235752A (ja) * 1985-04-11 1986-10-21 Asahi Optical Co Ltd 細胞分離材、分離器および分離方法
US4810378A (en) * 1986-04-21 1989-03-07 Miles Laboratories, Inc. Red blood cell filtering system
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
USRE33924E (en) * 1986-07-16 1992-05-12 Autologous Blood Corp. Apparatus and method for storing and processing blood
US4840730A (en) * 1986-07-25 1989-06-20 Sepragen Corporation Chromatography system using horizontal flow columns
US4714457A (en) * 1986-09-15 1987-12-22 Robert Alterbaum Method and apparatus for use in preparation of fibrinogen from a patient's blood
US4720284A (en) * 1986-10-03 1988-01-19 Neotech, Inc. Method and means for separation of blood components
JPS63102667A (ja) * 1986-10-17 1988-05-07 Kawasumi Lab Inc 培養装置
US4915847A (en) * 1987-08-04 1990-04-10 Baxter International Inc. Cryoglobulin separation
US4917804A (en) * 1986-10-31 1990-04-17 Baxter International Inc. Method and vessel for separation of cryoglobin
US4820297A (en) * 1986-12-12 1989-04-11 Baxter International Inc. Fluid delivery system with integrally formed sample cell
US4834890A (en) * 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
CA1325980C (en) * 1987-04-22 1994-01-11 Sho Kikyotani Apparatus for the treatment of biological samples and treatment methods using the same
US5211626A (en) * 1987-05-01 1993-05-18 Product Innovation Holdings Ltd. Medical infusion apparatus
US4939087A (en) * 1987-05-12 1990-07-03 Washington State University Research Foundation, Inc. Method for continuous centrifugal bioprocessing
US4909949A (en) * 1987-10-26 1990-03-20 Engineering & Research Associates Bridge for suspending a blood collection bag
JPH0221871A (ja) * 1988-07-12 1990-01-24 Asahi Medical Co Ltd 混合液から液体成分を分別・除去するためのディスポーザブルセット
US4892668A (en) * 1988-10-05 1990-01-09 Engineering & Research Associates, Inc. Blood collection bag support
DE3934625A1 (de) * 1988-10-19 1990-04-26 Leitz Wild Gmbh Automatisiertes "in vivo"-mikrokerntest-verfahren und vorrichtung zur durchfuehrung desselben
US5240601A (en) * 1988-11-09 1993-08-31 Chembiomed, Ltd. Affinity supports for hemoperfusion
US4994021A (en) * 1988-11-15 1991-02-19 Baxter International Inc. Apparatus and method for collecting and freezing blood plasma
US5009654A (en) * 1989-03-10 1991-04-23 Baxter International Inc. Sterile product and method for sterilizing and assembling such product
FR2647213B1 (fr) * 1989-05-22 1992-11-13 Centre Nat Rech Scient Systeme echantillonneur automatique d'un liquide biologique a prelevement sterile
US5254314A (en) * 1989-08-24 1993-10-19 International Mould Engineering Microcentrifuge tube
US5100564A (en) * 1990-11-06 1992-03-31 Pall Corporation Blood collection and processing system
EP0491858A1 (en) * 1989-09-14 1992-07-01 Baxter International Inc. Method and useful apparatus for preparing pharmaceutical compositions
US4994056A (en) * 1989-11-09 1991-02-19 Ikeda Daniel P Unit dose medicament storing and mixing system
DE69111480T2 (de) * 1990-02-14 1996-03-14 Shinsozai Sogo Kenkyusho Kk Gefüllter und abgedichteter, unabhängiger Mischbehälter.
WO1991016116A1 (en) * 1990-04-23 1991-10-31 Cellpro Incorporated Immunoselection device and method
US5224921A (en) * 1990-05-31 1993-07-06 Baxter International Inc. Small volume collection chamber
JP2584688B2 (ja) * 1990-08-17 1997-02-26 テルモ株式会社 液体分離装置および圧迫具
US5181910A (en) * 1991-02-28 1993-01-26 Pharmacia Deltec, Inc. Method and apparatus for a fluid infusion system with linearized flow rate change
US5180504A (en) * 1991-05-22 1993-01-19 Baxter International Inc. Systems and methods for removing undesired matter from blood cells
US5295964A (en) * 1991-10-02 1994-03-22 Gauthier Robert T Holder and warmer for IV solution containers
US5240856A (en) * 1991-10-23 1993-08-31 Cellpro Incorporated Apparatus for cell separation
US5314421A (en) * 1992-03-05 1994-05-24 Baxter International Inc. Blood pack labels and the like

Also Published As

Publication number Publication date
EP0746753A4 (en) 1998-04-15
CA2160009A1 (en) 1994-11-10
FI955015A0 (fi) 1995-10-20
JPH08509552A (ja) 1996-10-08
NZ265563A (en) 1998-05-27
NO954212D0 (no) 1995-10-20
US5672481A (en) 1997-09-30
AU6638994A (en) 1994-11-21
EP0746753A1 (en) 1996-12-11
FI955015A (fi) 1995-10-20
AU699784B2 (en) 1998-12-17
WO1994025848A1 (en) 1994-11-10
KR960702105A (ko) 1996-03-28

Similar Documents

Publication Publication Date Title
NO954212L (no) Apparat og fremgangsmåte for konsentrasjon og separasjon av partikler i et lukket område
JP5236141B2 (ja) Ｍｅｍｓを用いた医療システム、方法および装置
Hall et al. Evidence for the presence of volume-sensitive KCl transport in ‘young’human red cells
CA2113119A1 (en) Computer controlled cryoprotectant perfusion apparatus and method
NO865068L (no) System, fremgangsmaate og apparat til fraksjonering av blod in situ.
GB0003596D0 (en) Sperm separation
Badon et al. Survival of Borrelia burgdorferi in blood products
CA2107798C (en) Method for testing blood units for viral contamination
KR20210111266A (ko) 세포 가공 유닛, 세포 가공 시스템 및 이의 사용 방법
BR9714672A (pt) Processos para localizar o nìvel de leito de patìculas sedimentadas dentro de ums suspensão lìquida e para identificar uma névoa de partìcula não sedimentada dentro de um tanque de sedimentação, e, sistema para determinar o nìvel de leito de partìculas sedimentadas em uma suspensão
CN104198704A (zh) 一种百日咳诊断试剂盒及制备方法
Shortman Separation methods for lymphocyte populations
Toft et al. [14] Receptor identification by density gradient centrifugation
CN106749503A (zh) 一种一体式蛋白纯化层析装置
Trautman et al. Isodensity ultracentrifugation of foot-and-mouth disease virus in caesium chloride
JP2004536602A5 (no)
GB2166659A (en) Processing particulate material
ATE193212T1 (de) Vorrichtung zum trennen von flüssigkeiten
Little et al. In vitro studies of interaction of rickettsia and macrophages: Effect of ultraviolet light on Coxiella burnetii inactivation and macrophage enzymes
JPH0646937B2 (ja) 培養液の濃縮装置
Edelstein et al. Ascitic fluid culture technique
GB2339903A (en) Fluid container
SU908364A1 (ru) Установка дл гемосорбции
Keswick Survival of enteric viruses adsorbed on electropositive filters
Rácz Differential reduction in lymphocyte and granulocyte content by removal of the buffy coat from fresh and overnight-stored blood. Comparison of manual and automated blood processing systems

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application