NO951640L - Antimikrobielle 5-hydrazinokinolonderivater - Google Patents

Antimikrobielle 5-hydrazinokinolonderivater

Info

Publication number
NO951640L
NO951640L NO951640A NO951640A NO951640L NO 951640 L NO951640 L NO 951640L NO 951640 A NO951640 A NO 951640A NO 951640 A NO951640 A NO 951640A NO 951640 L NO951640 L NO 951640L
Authority
NO
Norway
Prior art keywords
hydrazinoquinolone
antimicrobial
derivatives
lower alkyl
heterocyclic ring
Prior art date
Application number
NO951640A
Other languages
English (en)
Norwegian (no)
Other versions
NO951640D0 (no
Inventor
Jr Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO951640D0 publication Critical patent/NO951640D0/no
Publication of NO951640L publication Critical patent/NO951640L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO951640A 1992-10-30 1995-04-28 Antimikrobielle 5-hydrazinokinolonderivater NO951640L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30
PCT/US1993/010091 WO1994010163A1 (fr) 1992-10-30 1993-10-22 Derives antimicrobiens de 5-hydrazino-quinolone

Publications (2)

Publication Number Publication Date
NO951640D0 NO951640D0 (no) 1995-04-28
NO951640L true NO951640L (no) 1995-06-30

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951640A NO951640L (no) 1992-10-30 1995-04-28 Antimikrobielle 5-hydrazinokinolonderivater

Country Status (21)

Country Link
EP (1) EP0666853A1 (fr)
JP (1) JPH08502750A (fr)
KR (1) KR950704301A (fr)
CN (1) CN1064357C (fr)
AU (1) AU687018B2 (fr)
BR (1) BR9307347A (fr)
CA (1) CA2148003A1 (fr)
CZ (1) CZ282581B6 (fr)
EG (1) EG20543A (fr)
FI (1) FI952049A0 (fr)
HU (1) HUT72072A (fr)
IL (1) IL107323A (fr)
MX (1) MX9306814A (fr)
NO (1) NO951640L (fr)
NZ (1) NZ257470A (fr)
PL (1) PL178094B1 (fr)
RU (1) RU2126000C1 (fr)
SG (1) SG59979A1 (fr)
SK (1) SK54795A3 (fr)
WO (1) WO1994010163A1 (fr)
ZA (1) ZA938089B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
NZ290722A (en) * 1994-08-02 1999-03-29 Procter & Gamble A process for making derivatives of quinolonyl lactam (qla's); intermediates
DE69515882T2 (de) * 1994-08-02 2000-11-02 Procter & Gamble Verfahren zur herstellung von antimikrobiellen verbindungen
CA2242242C (fr) * 1996-02-09 2001-08-07 Toyama Chemical Co., Ltd. Derives de l'acide quinolonecarboxylique et leurs sels
PT1901749T (pt) * 2005-05-18 2016-11-04 Raptor Pharmaceuticals Inc Fluoroquinolonas aerossolizadas e suas utilizações
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CA2528849C (fr) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Derives de quinoleine utilises comme agents antibacteriens
EA010601B1 (ru) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Производные хинолина в качестве антибактериальных агентов
CN101020647B (zh) * 2007-02-14 2011-03-30 杭州师范学院 一种β-环丙胺基丙烯酸(酯)的合成方法
JP5363350B2 (ja) * 2007-03-19 2013-12-11 武田薬品工業株式会社 Mapk/erkキナーゼ阻害剤
EP3092901B1 (fr) * 2007-10-05 2020-04-29 Senhwa Biosciences, Inc. Analogues de quinolone et procédés associés
WO2009147616A1 (fr) * 2008-06-03 2009-12-10 Actelion Pharmaceuticals Ltd Dérivés de [4-(1-amino-éthyl)-cyclohexyl]-méthyl-amine et de [6-(1-amino-ethyl)-tétrahydro-pyran-3-yl]-méthyl-amine
MX345158B (es) 2008-10-07 2017-01-18 Raptor Pharmaceuticals Inc Formulaciones de fluoroquinolona en aerosol para farmacocinetica mejorada.
HUE050147T2 (hu) 2008-10-07 2020-11-30 Horizon Orphan Llc Tüdõgyulladás csökkentése levofloxacin belélegzése útján
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
AU2010289326B2 (en) 2009-09-04 2015-09-24 Horizon Therapeutics U.S. Holding Llc Use of aerosolized levofloxacin for treating cystic fibrosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
WO1991002526A1 (fr) * 1989-08-16 1991-03-07 Pfizer Inc. Acides azabicyclo quinolone carboxyliques
ES2147721T3 (es) * 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
CA2095338C (fr) * 1990-11-30 2002-04-09 John Michael Domagala Utilisation des stereoisomeres individuels des 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolones et des naphthyridones comme agents antibacteriens

Also Published As

Publication number Publication date
CZ109795A3 (en) 1995-12-13
IL107323A (en) 2000-06-01
RU95110762A (ru) 1997-01-10
MX9306814A (es) 1994-07-29
NZ257470A (en) 1997-08-22
SG59979A1 (en) 1999-02-22
CA2148003A1 (fr) 1994-05-11
KR950704301A (ko) 1995-11-17
HUT72072A (en) 1996-03-28
FI952049A (fi) 1995-04-28
CN1092773A (zh) 1994-09-28
IL107323A0 (en) 1994-01-25
PL178094B1 (pl) 2000-02-29
PL308671A1 (en) 1995-08-21
BR9307347A (pt) 1999-05-25
ZA938089B (en) 1994-06-07
AU687018B2 (en) 1998-02-19
AU5409794A (en) 1994-05-24
EP0666853A1 (fr) 1995-08-16
CN1064357C (zh) 2001-04-11
HU9501237D0 (en) 1995-06-28
WO1994010163A1 (fr) 1994-05-11
FI952049A0 (fi) 1995-04-28
NO951640D0 (no) 1995-04-28
CZ282581B6 (cs) 1997-08-13
SK54795A3 (en) 1995-12-06
RU2126000C1 (ru) 1999-02-10
EG20543A (en) 1999-07-31
JPH08502750A (ja) 1996-03-26

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