NO942864L - Benzokondenserte 5-ringheterocykler, fremgangsmåte for fremstilling derav, deres anvendelse som medikament, deres anvendelse som diagnostikum samt medikament inneholdene disse - Google Patents
Benzokondenserte 5-ringheterocykler, fremgangsmåte for fremstilling derav, deres anvendelse som medikament, deres anvendelse som diagnostikum samt medikament inneholdene disseInfo
- Publication number
- NO942864L NO942864L NO942864A NO942864A NO942864L NO 942864 L NO942864 L NO 942864L NO 942864 A NO942864 A NO 942864A NO 942864 A NO942864 A NO 942864A NO 942864 L NO942864 L NO 942864L
- Authority
- NO
- Norway
- Prior art keywords
- drug
- benzo
- diagnostic
- condensed
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4326005A DE4326005A1 (de) | 1993-08-03 | 1993-08-03 | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
DE19944414316 DE4414316A1 (de) | 1994-04-25 | 1994-04-25 | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
Publications (3)
Publication Number | Publication Date |
---|---|
NO942864D0 NO942864D0 (no) | 1994-08-02 |
NO942864L true NO942864L (no) | 1995-02-06 |
NO301584B1 NO301584B1 (no) | 1997-11-17 |
Family
ID=25928286
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO942864A NO301584B1 (no) | 1993-08-03 | 1994-08-02 | Benzokondenserte 5-ringheterocykler, deres anvendelse til fremstilling av medikament og diagnostikum, samt medikamenter inneholdende disse |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0639573A1 (no) |
JP (1) | JPH07145149A (no) |
KR (2) | KR100343292B1 (no) |
CN (1) | CN1118347A (no) |
AU (1) | AU682371B2 (no) |
CA (1) | CA2129301A1 (no) |
FI (1) | FI943579A (no) |
HU (1) | HU218790B (no) |
IL (1) | IL110503A (no) |
NO (1) | NO301584B1 (no) |
NZ (1) | NZ264130A (no) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6169107B1 (en) | 1993-04-28 | 2001-01-02 | Sumitomo Pharmaceutical Co., Ltd. | Indoloylguanidine derivatives |
CA2121391A1 (en) * | 1993-04-28 | 1994-10-29 | Atsuyuki Kojima | Indoloylguanidine derivatives |
DE4412334A1 (de) * | 1994-04-11 | 1995-10-19 | Hoechst Ag | Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
AU683552B2 (en) * | 1994-04-11 | 1997-11-13 | Chugai Seiyaku Kabushiki Kaisha | 4,6-DI-t-butyl-2,3-dihydrobenzothiophene derivative |
CA2160600A1 (en) * | 1994-10-18 | 1996-04-19 | Masahumi Kitano | Indoloylguanidine derivatives |
US5834466A (en) * | 1994-12-22 | 1998-11-10 | The Regents Of The University Of California | Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia |
ATE183498T1 (de) * | 1995-04-18 | 1999-09-15 | Hoechst Ag | Substituierte indenoylguanidines mit antiarrhythmischer und cardioprotektiver wirkung |
DE19540995A1 (de) * | 1995-11-03 | 1997-05-07 | Hoechst Ag | Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19542306A1 (de) * | 1995-11-14 | 1997-05-15 | Hoechst Ag | Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
PL316439A1 (en) * | 1995-11-20 | 1997-05-26 | Hoechst Ag | Novel substituted derivatives of benzoyloguanidine, method of obtaining them, their application in production of pharmaceutic and diagnostic agents and pharmaceutic agent as such |
DE19546736A1 (de) * | 1995-12-14 | 1997-06-19 | Hoechst Ag | Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate |
DE19548708A1 (de) * | 1995-12-23 | 1997-06-26 | Merck Patent Gmbh | Cyclische Sulfone |
DE19548812A1 (de) * | 1995-12-27 | 1997-07-03 | Hoechst Ag | Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikaments zur Atemstimulation |
CA2195697A1 (en) * | 1996-02-02 | 1997-08-03 | Masahumi Kitano | Novel substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof |
AU2193797A (en) * | 1996-03-01 | 1997-09-16 | Chiron Corporation | Delivery of therapeutic agents to the prostate |
JP2002502414A (ja) * | 1997-06-02 | 2002-01-22 | 藤沢薬品工業株式会社 | 細胞中のNa▲上+▼/H▲上+▼交換の阻害剤としてのグアニジン誘導体 |
GB9716657D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
US6011059A (en) * | 1997-12-24 | 2000-01-04 | Bristol-Myers Squibb Company | Acyl guanidine sodium/proton exchange inhibitors and method |
US6160134A (en) * | 1997-12-24 | 2000-12-12 | Bristol-Myers Squibb Co. | Process for preparing chiral cyclopropane carboxylic acids and acyl guanidines |
CA2260499A1 (en) * | 1998-01-29 | 1999-07-29 | Sumitomo Pharmaceuticals Company Limited | Pharmaceutical compositions for the treatment of ischemic brain damage |
GB9803226D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
KR20030083004A (ko) * | 1998-02-27 | 2003-10-23 | 화이자 프로덕츠 인크. | 허혈 치료용 n-[(치환된 5원 디아자 이불포화고리)카르보닐] 구아니딘 유도체 |
CN101284865A (zh) | 1998-11-05 | 2008-10-15 | 富山化学工业株式会社 | 新型化合物及其医药用途 |
GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902452D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902459D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902455D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902453D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
WO2000064445A1 (en) | 1999-04-23 | 2000-11-02 | Bristol-Myers Squibb Company | Bicyclic acyl guanidine sodium/proton exchange inhibitors and method |
EP1238971A4 (en) * | 1999-12-16 | 2003-02-26 | Sumitomo Pharma | SUBSTITUTED GUANIDINE DERIVATIVES |
GB0000625D0 (en) | 2000-01-13 | 2000-03-01 | Zeneca Ltd | Chemical compounds |
WO2002051805A1 (de) | 2000-12-27 | 2002-07-04 | Bayer Aktiengesellschaft | Indol-derivate |
DE10163239A1 (de) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituierte Imidazolidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie enthaltendes Medikament |
TWI350285B (en) | 2002-03-13 | 2011-10-11 | Array Biopharma Inc | N3 alkylated benzimidazole derivatives as mek inhibitors |
FR2842526B1 (fr) * | 2002-07-16 | 2007-07-13 | Aventis Pharma Sa | Compositions pharmaceutiques contenant un derive de 3-guanidinocarbonyl-1-heteroaryl-indole, procede de preparation a titre de medicaments |
FR2842525B1 (fr) * | 2002-07-16 | 2005-05-13 | Aventis Pharma Sa | Derives de 3-guanidinocarbonyl-1-heteroaryl-indole, procede de preparation a titre de medicaments et compositions pharmaceutiques les renfermant |
US7141600B2 (en) | 2003-04-15 | 2006-11-28 | The Regents Of The University Of California | Small molecule inhibition of a PDZ-domain interaction |
FR2856062B1 (fr) * | 2003-06-12 | 2005-11-11 | Aventis Pharma Sa | Derives 3-guanidinocarbonyl-heterocycle, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant |
KR20070028553A (ko) | 2004-06-18 | 2007-03-12 | 바이올리폭스 에이비 | 염증 치료에 유용한 인돌 |
CN101014568A (zh) | 2004-07-01 | 2007-08-08 | 加利福尼亚大学董事会 | 抑制pdz-结构域相互作用的小分子 |
US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7645881B2 (en) | 2004-07-22 | 2010-01-12 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
CA2594221C (en) * | 2004-12-27 | 2010-09-21 | Yuyu Inc. | Benzothiophen-2-carbonylguanidine derivatives, preparation thereof, and pharmaceutical composition containing the same |
WO2006077366A1 (en) | 2005-01-19 | 2006-07-27 | Biolipox Ab | Indoles useful in the treatment of inflammation |
KR100644385B1 (ko) * | 2005-02-25 | 2006-11-10 | 동양수기산업(주) | 흡입식 슬러지 수집기 |
US8076348B2 (en) | 2005-08-08 | 2011-12-13 | Astellas Pharma Inc. | Acylguanidine derivative or salt thereof |
TWI387592B (zh) | 2005-08-30 | 2013-03-01 | Novartis Ag | 經取代之苯并咪唑及其作為與腫瘤形成相關激酶之抑制劑之方法 |
KR20080085014A (ko) | 2005-12-09 | 2008-09-22 | 에프. 호프만-라 로슈 아게 | 비만 치료에 유용한 트라이사이클릭 아마이드 유도체 |
UA95788C2 (en) | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
US7645752B2 (en) | 2006-01-13 | 2010-01-12 | Wyeth Llc | Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors |
CN101384550B (zh) * | 2006-02-20 | 2011-08-31 | 安斯泰来制药株式会社 | 酰胺衍生物或其盐 |
EP1988075B1 (en) | 2006-02-20 | 2012-01-25 | Astellas Pharma Inc. | Pyrrole derivative or salt thereof |
SG177918A1 (en) * | 2006-12-26 | 2012-02-28 | Lantheus Medical Imaging Inc | Ligands for imaging cardiac innervation |
MX336731B (es) | 2010-01-28 | 2016-01-28 | Harvard College | Composiciones y metodos para potenciar la actividad de proteasoma. |
US8759535B2 (en) | 2010-02-18 | 2014-06-24 | High Point Pharmaceuticals, Llc | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof |
ES2724531T3 (es) | 2011-05-12 | 2019-09-11 | Proteostasis Therapeutics Inc | Reguladores de proteostasis |
US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
US10093640B2 (en) | 2012-09-21 | 2018-10-09 | Vanderbilt University | Substituted benzofuran, benzothiophene and indole MCL-1 inhibitors |
WO2014116228A1 (en) | 2013-01-25 | 2014-07-31 | President And Fellows Of Harvard College | Usp14 inhibitors for treating or preventing viral infections |
US9394285B2 (en) | 2013-03-15 | 2016-07-19 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
EP3038618B1 (en) | 2013-08-28 | 2020-10-14 | Vanderbilt University | Substituted indole mcl-1 inhibitors |
WO2015073528A1 (en) | 2013-11-12 | 2015-05-21 | Proteostasis Therapeutics, Inc. | Proteasome activity enhancing compounds |
EP3122353B1 (en) | 2014-03-27 | 2020-10-28 | Vanderbilt University | Substituted indole mcl-1 inhibitors |
HUE055262T2 (hu) | 2014-08-11 | 2021-11-29 | Angion Biomedica Corp | Citokróm P450 inhibitorok és ezek alkalmazásai |
CN105884675A (zh) * | 2014-09-24 | 2016-08-24 | 中国药科大学 | N-取代吲哚羧酸衍生物、其制法及医药用途 |
US9949965B2 (en) | 2014-10-17 | 2018-04-24 | Vanderbilt University | Tricyclic indole Mcl-1 inhibitors and uses thereof |
WO2016089648A1 (en) | 2014-12-01 | 2016-06-09 | Vtv Therapeutics Llc | Bach 1 inhibitors in combination with nrf2 activators and pharmaceutical compositions thereof |
WO2016109492A1 (en) | 2014-12-31 | 2016-07-07 | Angion Biomedica Corp | Methods and agents for treating disease |
AU2017228385B2 (en) | 2016-03-04 | 2021-11-04 | Vanderbilt University | Substituted indole Mcl-1 inhibitors |
CN105820132B (zh) * | 2016-05-12 | 2018-11-13 | 广西师范大学 | N-芳基苯并三唑类氮氧衍生物及其合成方法 |
CN105968059B (zh) * | 2016-05-12 | 2018-11-13 | 广西师范大学 | N-烯基苯并三唑类氮氧衍生物及其制备方法和应用 |
CN111960985A (zh) * | 2018-08-08 | 2020-11-20 | 中国人民解放军总医院 | 抗肿瘤化合物 |
JP2023525047A (ja) | 2020-05-06 | 2023-06-14 | エイジャックス セラピューティクス, インコーポレイテッド | Jak2阻害薬としての6-ヘテロアリールオキシベンゾイミダゾール及びアザベンゾイミダゾール |
CN113967210A (zh) * | 2020-07-24 | 2022-01-25 | 上海交通大学医学院附属瑞金医院 | 一种干扰整合素β3/Src相互作用的化合物的用途 |
WO2023086319A1 (en) | 2021-11-09 | 2023-05-19 | Ajax Therapeutics, Inc. | 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4544670A (en) * | 1982-08-24 | 1985-10-01 | William H. Rorer, Inc. | Method of treating coccidiosis with acyl guanidines |
DE3304019A1 (de) * | 1983-02-07 | 1984-08-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 3-acyloxy-1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
DE4127026A1 (de) * | 1991-08-16 | 1993-02-18 | Boehringer Ingelheim Kg | Neue pyrazinderivate, ihre herstellung und verwendung |
-
1994
- 1994-07-28 EP EP94111765A patent/EP0639573A1/de not_active Withdrawn
- 1994-07-29 NZ NZ264130A patent/NZ264130A/en unknown
- 1994-07-29 IL IL11050394A patent/IL110503A/xx not_active IP Right Cessation
- 1994-08-01 AU AU68844/94A patent/AU682371B2/en not_active Ceased
- 1994-08-01 FI FI943579A patent/FI943579A/fi unknown
- 1994-08-02 NO NO942864A patent/NO301584B1/no not_active IP Right Cessation
- 1994-08-02 CA CA002129301A patent/CA2129301A1/en not_active Abandoned
- 1994-08-02 CN CN94109516A patent/CN1118347A/zh active Pending
- 1994-08-02 KR KR1019940019259A patent/KR100343292B1/ko not_active IP Right Cessation
- 1994-08-02 JP JP6198940A patent/JPH07145149A/ja active Pending
- 1994-08-02 KR KR1019940019071A patent/KR950005817A/ko not_active Application Discontinuation
- 1994-08-03 HU HU9402271A patent/HU218790B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR950005512A (ko) | 1995-03-20 |
NZ264130A (en) | 1995-12-21 |
NO942864D0 (no) | 1994-08-02 |
AU6884494A (en) | 1995-02-16 |
KR950005817A (ko) | 1995-03-20 |
FI943579A (fi) | 1995-02-04 |
IL110503A0 (en) | 1994-10-21 |
EP0639573A1 (de) | 1995-02-22 |
KR100343292B1 (ko) | 2002-12-26 |
IL110503A (en) | 2000-06-29 |
JPH07145149A (ja) | 1995-06-06 |
HU218790B (hu) | 2000-12-28 |
AU682371B2 (en) | 1997-10-02 |
CA2129301A1 (en) | 1995-02-04 |
HUT70547A (en) | 1995-10-30 |
NO301584B1 (no) | 1997-11-17 |
FI943579A0 (fi) | 1994-08-01 |
HU9402271D0 (en) | 1994-09-28 |
CN1118347A (zh) | 1996-03-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO942864L (no) | Benzokondenserte 5-ringheterocykler, fremgangsmåte for fremstilling derav, deres anvendelse som medikament, deres anvendelse som diagnostikum samt medikament inneholdene disse | |
NO923466D0 (no) | Heterocykliske forbindelser med 5 ledd, fremgangsmaate forfremstilling, samt legemidler som inneholder disse forbindelser | |
DK654589A (da) | Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne | |
NO304468B1 (no) | 6-leddede nitrogenholdige heteroaryl-oksazolidinoner, anvendelse av disse samt legemiddel inneholdende forbindelsen | |
NO179911C (no) | Optisk aktivt 5H-pyrrolo[3,4-bÅpyrazinderivat samt farmasöytiske preparater inneholdende derivatet | |
NO944700D0 (no) | Nye tienotiazinderivater, fremgangsmåte for fremstilling derav samt farmasöytiske preparater inneholdende forbindelsene | |
NO304488B1 (no) | 5-leddede heteroaryloksazolidinoner, anvendelse av disse for fremstilling av legemidler samt legemiddel inneholdende forbindelsen | |
NO894270L (no) | Synergistisk soetningsmiddel, samt fremgangsmaate for fremstilling av et slikt. | |
FI940378A0 (fi) | 5-jäseniset heterosyklit, menetelmä niiden valmistamiseksi ja näitä yhdisteitä sisältävät lääkeaineet | |
NO890926D0 (no) | Triazolderivater, fremgangsmaate til fremstilling derav samt deres anvendelse som soppdrepende midler. | |
NO980273D0 (no) | Femleddede heterocykluser med bifenylsulfonylsubstitusjon fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen | |
DK219387D0 (da) | Aminothiazol- og aminooxazolderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende disse | |
NO308287B1 (no) | Substituerte 4-fenyl-6-amino-nikotinsyrederivater, legemidler inneholdende disse samt deres anvendelse | |
DK276189D0 (da) | Polypeptidforbindelser, fremgangsmaader til fremstilling heraf farmaceutiske midler indeholdende disse | |
DK378988A (da) | Dopamin-beta-hydroxylaseinhibitorer, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse forbindelser | |
NO902786L (no) | Krympeverktoey samt fremgangsmaate for bruk av dette. | |
NO960364D0 (no) | Basisk-substituerte benzolguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen | |
DK486789D0 (da) | Benzoxazolinonderivater, fremgangsmaader til fremstilling deraf samt farmaceutiske midler indeholdende disse | |
DK135988A (da) | 2,5-dihydropyrroler, fremgangsmaader til deres fremstilling samt deres anvendelse som herbicider | |
NO985171L (no) | Sulfonamidsubstituerte kondenserte 5-ringforbindelser, deres anvendelse som medikament samt farmas°ytiske preparater inneholdende forbindelsene | |
DK553689A (da) | Phenyloxypropanolaminderivater, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse | |
NO954739D0 (no) | Substituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende disse forbindelsene | |
DK266289D0 (da) | Alfa-adrenerge receptorantagonister, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse antagonister | |
NO970140D0 (no) | Technetium-sulfonamidkomplekser, deres anvendelse, farmasöytiske midler inneholdende disse, samt fremgangsmåte for fremstilling av kompleksene og midlene | |
DK165978C (da) | 1-aminoethyl-1h-imidazolderivater, fremgangsmaader til fremstilling deraf samt antimykotiske midler indeholdende disse |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN FEBRUARY 2002 |