NO941681L - Humane IL-4 mutant proteiner - Google Patents

Humane IL-4 mutant proteiner

Info

Publication number
NO941681L
NO941681L NO941681A NO941681A NO941681L NO 941681 L NO941681 L NO 941681L NO 941681 A NO941681 A NO 941681A NO 941681 A NO941681 A NO 941681A NO 941681 L NO941681 L NO 941681L
Authority
NO
Norway
Prior art keywords
pct
date
human
mutant proteins
antagonists
Prior art date
Application number
NO941681A
Other languages
English (en)
Other versions
NO941681D0 (no
NO312707B1 (no
Inventor
Walter Sebald
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6444719&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO941681(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO941681D0 publication Critical patent/NO941681D0/no
Publication of NO941681L publication Critical patent/NO941681L/no
Publication of NO312707B1 publication Critical patent/NO312707B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5406IL-4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO19941681A 1991-11-13 1994-05-06 Terapeutiske midler omfattende humane IL-4 mutantproteiner samt fremgangsmåte for fremstilling derav NO312707B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4137333A DE4137333A1 (de) 1991-11-13 1991-11-13 Therapeutische mittel, die antagonisten oder partielle agonisten des humanen interleukin 4 sind oder diese enthalten, hil-4-mutantenproteine sowie vefahren zu deren herstellung
PCT/EP1992/002614 WO1993010235A1 (de) 1991-11-13 1992-11-13 Menschliche il-4 mutantenproteine

Publications (3)

Publication Number Publication Date
NO941681D0 NO941681D0 (no) 1994-05-06
NO941681L true NO941681L (no) 1994-05-06
NO312707B1 NO312707B1 (no) 2002-06-24

Family

ID=6444719

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19941681A NO312707B1 (no) 1991-11-13 1994-05-06 Terapeutiske midler omfattende humane IL-4 mutantproteiner samt fremgangsmåte for fremstilling derav

Country Status (16)

Country Link
US (1) US5723118A (no)
EP (1) EP0613499B2 (no)
JP (2) JP3470970B2 (no)
KR (1) KR100276410B1 (no)
AT (1) ATE163196T1 (no)
AU (1) AU671960B2 (no)
CA (1) CA2123315C (no)
CZ (1) CZ283467B6 (no)
DE (2) DE4137333A1 (no)
DK (1) DK0613499T4 (no)
ES (1) ES2112340T5 (no)
GR (1) GR3026600T3 (no)
HU (1) HU217326B (no)
NO (1) NO312707B1 (no)
SK (1) SK280114B6 (no)
WO (1) WO1993010235A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4423131A1 (de) * 1994-07-01 1996-01-04 Bayer Ag Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
GB9415379D0 (en) * 1994-07-29 1994-09-21 Smithkline Beecham Plc Novel compounds
AU3382595A (en) * 1994-07-29 1996-03-04 Smithkline Beecham Corporation Novel compounds
PL187846B1 (pl) * 1996-06-14 2004-10-29 Bayer Ag Agoniści interleukiny-4 wybiórczy dla limfocytów T
US5986059A (en) * 1996-06-14 1999-11-16 Bayer Corporation T-cell selective interleukin-4 agonists
US6335426B1 (en) 1996-06-14 2002-01-01 Bayer Corporation T-cell selective interleukin-4 agonists
MY124565A (en) * 1996-07-19 2006-06-30 Bayer Corp High-affinity interleukin-4-muteins
US6180108B1 (en) * 1998-12-10 2001-01-30 Bayer Corporation Vectors having terminal repeat sequence of Epstein-Barr virus
DE10022258A1 (de) 2000-05-08 2001-11-15 Bayer Ag Reinigung von Proteineinschlusskörpern durch Querstrom-Mikrofiltration
EP2990420B1 (en) 2000-05-26 2016-12-21 Immunex Corporation Use of interleukin-4 receptor antibodies and compositions thereof
GB0105360D0 (en) * 2001-03-03 2001-04-18 Glaxo Group Ltd Chimaeric immunogens
EP1314739A1 (en) 2001-11-22 2003-05-28 Bayer Ag Process for renaturation of recombinant, disulfide containing proteins at high protein concentrations in the presence of amines
EP1382614A1 (en) * 2002-07-15 2004-01-21 Bayer HealthCare AG Process for the purification of interleukin-4 and its muteins
US7635754B2 (en) * 2004-09-22 2009-12-22 Aerovance, Inc. Interleukin-9 and interleukin-4 chimeric antagonist muteins and methods of using same
US20070009479A1 (en) * 2005-06-17 2007-01-11 Aerovance, Inc. Methods for treating dermatitis using mutant human IL-4 compositions
AU2007263265A1 (en) * 2006-06-21 2007-12-27 Apogenix Gmbh Differential IL-4 and/or IL-10 cytokine expression in human cancer
AU2007271349A1 (en) * 2006-07-06 2008-01-10 Apogenix Gmbh Human IL-4 muteins in combination with chemotherapeutics or pro-apoptotic agents in cancer therapy
EP2596802A1 (en) 2011-11-23 2013-05-29 PLS-Design GmbH Pharmaceutical composition for treatment of allergic reactions
EP2674168A1 (en) 2012-06-14 2013-12-18 PLS-Design GmbH Modulation of effector T cell responses by local depletion of complement component C3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US5041381A (en) * 1986-07-03 1991-08-20 Schering Corporation Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
KR900700132A (ko) * 1988-02-02 1990-08-11 에릭 에스. 딕커 면역 글로불린 e 반응 억제 방법
US5188827A (en) * 1989-12-18 1993-02-23 Schering Corporation Use of interleukin-4- for lowering blood-cholesterol levels

Also Published As

Publication number Publication date
DE4137333A1 (de) 1993-05-19
DK0613499T4 (da) 2005-04-18
US5723118A (en) 1998-03-03
WO1993010235A1 (de) 1993-05-27
ES2112340T5 (es) 2005-10-16
CZ283467B6 (cs) 1998-04-15
NO941681D0 (no) 1994-05-06
SK280114B6 (sk) 1999-08-06
HUT66826A (en) 1995-01-30
NO312707B1 (no) 2002-06-24
HU217326B (hu) 1999-12-28
JPH07501522A (ja) 1995-02-16
GR3026600T3 (en) 1998-07-31
EP0613499B1 (de) 1998-02-11
HU9401369D0 (en) 1994-08-29
EP0613499A1 (de) 1994-09-07
KR100276410B1 (ko) 2000-12-15
CZ118594A3 (en) 1994-12-15
CA2123315A1 (en) 1993-05-27
AU671960B2 (en) 1996-09-19
EP0613499B2 (de) 2005-03-30
JP2003174894A (ja) 2003-06-24
AU2928292A (en) 1993-06-15
DK0613499T3 (da) 1998-09-23
SK55494A3 (en) 1994-12-07
JP3470970B2 (ja) 2003-11-25
ATE163196T1 (de) 1998-02-15
DE59209196D1 (de) 1998-03-19
CA2123315C (en) 2003-06-17
ES2112340T3 (es) 1998-04-01

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