NO911229L - Fremstilling av anvendelige beta-ketoestere ved fremstilling av kinolonantibiotika. - Google Patents

Fremstilling av anvendelige beta-ketoestere ved fremstilling av kinolonantibiotika.

Info

Publication number
NO911229L
NO911229L NO91911229A NO911229A NO911229L NO 911229 L NO911229 L NO 911229L NO 91911229 A NO91911229 A NO 91911229A NO 911229 A NO911229 A NO 911229A NO 911229 L NO911229 L NO 911229L
Authority
NO
Norway
Prior art keywords
preparation
ketosters
quinolon
antibiotics
useful beta
Prior art date
Application number
NO91911229A
Other languages
English (en)
Norwegian (no)
Other versions
NO911229D0 (no
Inventor
Brian T O'neill
Frank R Busch
Richard S Lehner
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO911229D0 publication Critical patent/NO911229D0/no
Publication of NO911229L publication Critical patent/NO911229L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO91911229A 1990-03-27 1991-03-26 Fremstilling av anvendelige beta-ketoestere ved fremstilling av kinolonantibiotika. NO911229L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50015590A 1990-03-27 1990-03-27

Publications (2)

Publication Number Publication Date
NO911229D0 NO911229D0 (no) 1991-03-26
NO911229L true NO911229L (no) 1991-09-30

Family

ID=23988274

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91911229A NO911229L (no) 1990-03-27 1991-03-26 Fremstilling av anvendelige beta-ketoestere ved fremstilling av kinolonantibiotika.

Country Status (22)

Country Link
US (1) US5380860A (ko)
EP (1) EP0449445A3 (ko)
JP (1) JPH0648990A (ko)
KR (1) KR930005059B1 (ko)
CN (1) CN1041083C (ko)
AU (1) AU617066B1 (ko)
BR (1) BR9101188A (ko)
CA (1) CA2039306C (ko)
EG (1) EG19607A (ko)
FI (1) FI911465A (ko)
HU (1) HUT56826A (ko)
IE (1) IE910991A1 (ko)
IL (1) IL97617A (ko)
MY (1) MY108069A (ko)
NO (1) NO911229L (ko)
NZ (1) NZ237555A (ko)
PH (1) PH30994A (ko)
PL (1) PL289582A1 (ko)
PT (1) PT97130B (ko)
RU (1) RU2058977C1 (ko)
YU (1) YU53991A (ko)
ZA (1) ZA912263B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
KR100372563B1 (ko) * 1996-12-16 2003-11-20 주식회사 엘지생명과학 퀴놀론계항생제중간체인베타-케토에스테르유도체의제조방법
KR100484386B1 (ko) * 2000-10-04 2005-04-22 경동제약 주식회사 알킬2-[2,3,5-트리플루오로-4-(4-메틸-1-피페라지닐)]벤조일-3(s)-(1-히드록시프로피-2-닐아미노)아크릴레이트의 제조방법
KR100589966B1 (ko) * 2001-10-15 2006-06-15 주식회사 엘지생명과학 베타-케토에스테르 화합물의 제조방법
KR100843125B1 (ko) * 2005-09-16 2008-07-02 주식회사 엘지생명과학 베타-케토에스테르 화합물의 제조방법
EP1943209B1 (en) * 2005-09-16 2012-06-27 LG Life Sciences Ltd. A process for preparing beta-ketoester compounds
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
RU2558932C1 (ru) * 2014-05-22 2015-08-10 Открытое Акционерное Общество "Татхимфармпрепараты" Фармацевтическая композиция моксифлоксацина и способ ее приготовления

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4014919A (en) * 1974-03-01 1977-03-29 The Dow Chemical Company Process for preparing methyl jasmonate and related compounds
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
DE3426482A1 (de) * 1984-07-18 1986-01-30 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von halogenierten aroylessigestern
DE3508816A1 (de) * 1985-01-10 1986-07-10 Bayer Ag, 5090 Leverkusen 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren
JPH0629246B2 (ja) * 1985-02-18 1994-04-20 富山化学工業株式会社 2−(5−フルオロニコチノイル)酢酸誘導体およびその塩
AT392789B (de) * 1985-01-23 1991-06-10 Toyama Chemical Co Ltd Verfahren zur herstellung von 1-substituierten aryl-1,4-dihydro-4-oxonaphthyridinderivaten
IL82401A0 (en) * 1986-05-06 1987-11-30 Merrell Dow Pharma Dopamine beta hydroxy-lase inhibiting imidazole derivatives and pharmaceutical compositions containing them
EP0251308B1 (de) * 1986-07-04 1990-11-22 Chemie Linz Gesellschaft m.b.H. 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3641343A1 (de) * 1986-12-03 1988-06-16 Hoechst Ag Carbamoylimidazol-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
DE3853654T2 (de) * 1987-08-14 1996-01-18 Asahi Glass Co Ltd Fluorierte Benzoylverbindungen.
US4833270A (en) * 1987-12-21 1989-05-23 American Cyanamid Company Process for preparing 2-chloro-4,5-difluorobenzoic acid
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
EP0342849A3 (en) * 1988-05-19 1990-03-14 Pfizer Inc. Intermediates for preparing 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid esters
JPH0225462A (ja) * 1988-06-06 1990-01-26 Eli Lilly & Co β―ラクタム抗生物質の製造法およびその中間体
US4883270A (en) * 1989-02-09 1989-11-28 Maag Henry H Four-bar variable-resistance frontal calf developing machine
IE66202B1 (en) * 1989-08-16 1995-12-13 Pfizer Azabicyclo quinolone carboxylic acids

Also Published As

Publication number Publication date
CA2039306C (en) 1999-01-26
YU53991A (sh) 1993-11-16
PL289582A1 (en) 1992-06-01
EG19607A (en) 1995-07-27
JPH0648990A (ja) 1994-02-22
EP0449445A2 (en) 1991-10-02
CN1041083C (zh) 1998-12-09
IL97617A (en) 1998-08-16
HUT56826A (en) 1991-10-28
RU2058977C1 (ru) 1996-04-27
IE910991A1 (en) 1991-10-09
EP0449445A3 (en) 1993-08-25
FI911465A0 (fi) 1991-03-26
MY108069A (en) 1996-08-15
PH30994A (en) 1997-12-23
PT97130A (pt) 1991-11-29
US5380860A (en) 1995-01-10
NZ237555A (en) 1993-08-26
KR930005059B1 (ko) 1993-06-15
FI911465A (fi) 1991-09-28
KR920018007A (ko) 1992-10-21
ZA912263B (en) 1992-11-25
CN1055177A (zh) 1991-10-09
PT97130B (pt) 1999-02-26
IL97617A0 (en) 1992-06-21
AU617066B1 (en) 1991-11-14
CA2039306A1 (en) 1991-09-28
NO911229D0 (no) 1991-03-26
BR9101188A (pt) 1991-11-05

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