PT97130A - Processo para a preparacao de beta-cetoesteres uteis na preparacao de antibioticos quinolona - Google Patents

Processo para a preparacao de beta-cetoesteres uteis na preparacao de antibioticos quinolona

Info

Publication number
PT97130A
PT97130A PT97130A PT9713091A PT97130A PT 97130 A PT97130 A PT 97130A PT 97130 A PT97130 A PT 97130A PT 9713091 A PT9713091 A PT 9713091A PT 97130 A PT97130 A PT 97130A
Authority
PT
Portugal
Prior art keywords
preparation
cetoesters
quinolone
uterine
antibiotics
Prior art date
Application number
PT97130A
Other languages
English (en)
Other versions
PT97130B (pt
Inventor
Brian T O'neill
Frank R Busch
Richard S Lehner
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT97130A publication Critical patent/PT97130A/pt
Publication of PT97130B publication Critical patent/PT97130B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
PT97130A 1990-03-27 1991-03-25 Processo para a preparacao de beta-cetoesteres uteis na preparacao de antibioticos quinolona PT97130B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50015590A 1990-03-27 1990-03-27

Publications (2)

Publication Number Publication Date
PT97130A true PT97130A (pt) 1991-11-29
PT97130B PT97130B (pt) 1999-02-26

Family

ID=23988274

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97130A PT97130B (pt) 1990-03-27 1991-03-25 Processo para a preparacao de beta-cetoesteres uteis na preparacao de antibioticos quinolona

Country Status (22)

Country Link
US (1) US5380860A (pt)
EP (1) EP0449445A3 (pt)
JP (1) JPH0648990A (pt)
KR (1) KR930005059B1 (pt)
CN (1) CN1041083C (pt)
AU (1) AU617066B1 (pt)
BR (1) BR9101188A (pt)
CA (1) CA2039306C (pt)
EG (1) EG19607A (pt)
FI (1) FI911465A (pt)
HU (1) HUT56826A (pt)
IE (1) IE910991A1 (pt)
IL (1) IL97617A (pt)
MY (1) MY108069A (pt)
NO (1) NO911229L (pt)
NZ (1) NZ237555A (pt)
PH (1) PH30994A (pt)
PL (1) PL289582A1 (pt)
PT (1) PT97130B (pt)
RU (1) RU2058977C1 (pt)
YU (1) YU53991A (pt)
ZA (1) ZA912263B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
KR100372563B1 (ko) * 1996-12-16 2003-11-20 주식회사 엘지생명과학 퀴놀론계항생제중간체인베타-케토에스테르유도체의제조방법
KR100484386B1 (ko) * 2000-10-04 2005-04-22 경동제약 주식회사 알킬2-[2,3,5-트리플루오로-4-(4-메틸-1-피페라지닐)]벤조일-3(s)-(1-히드록시프로피-2-닐아미노)아크릴레이트의 제조방법
ES2294179T3 (es) * 2001-10-15 2008-04-01 Lg Life Sciences Ltd. Nuevo procedimiento para la preparacion de derivados de beta-ceto-ester intermediarios en la sintesis de antibioticos.
US7642356B2 (en) * 2005-09-16 2010-01-05 Lg Life Sciences Ltd. Process for preparing beta-ketoester compounds
KR100843125B1 (ko) * 2005-09-16 2008-07-02 주식회사 엘지생명과학 베타-케토에스테르 화합물의 제조방법
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
RU2558932C1 (ru) * 2014-05-22 2015-08-10 Открытое Акционерное Общество "Татхимфармпрепараты" Фармацевтическая композиция моксифлоксацина и способ ее приготовления

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4014919A (en) * 1974-03-01 1977-03-29 The Dow Chemical Company Process for preparing methyl jasmonate and related compounds
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
DE3426482A1 (de) * 1984-07-18 1986-01-30 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von halogenierten aroylessigestern
DE3508816A1 (de) * 1985-01-10 1986-07-10 Bayer Ag, 5090 Leverkusen 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren
AT392789B (de) * 1985-01-23 1991-06-10 Toyama Chemical Co Ltd Verfahren zur herstellung von 1-substituierten aryl-1,4-dihydro-4-oxonaphthyridinderivaten
JPH0629246B2 (ja) * 1985-02-18 1994-04-20 富山化学工業株式会社 2−(5−フルオロニコチノイル)酢酸誘導体およびその塩
IL82401A0 (en) * 1986-05-06 1987-11-30 Merrell Dow Pharma Dopamine beta hydroxy-lase inhibiting imidazole derivatives and pharmaceutical compositions containing them
DE3766299D1 (de) * 1986-07-04 1991-01-03 Chemie Linz Gmbh 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
DE3641343A1 (de) * 1986-12-03 1988-06-16 Hoechst Ag Carbamoylimidazol-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
DE3853654T2 (de) * 1987-08-14 1996-01-18 Asahi Glass Co Ltd Fluorierte Benzoylverbindungen.
US4833270A (en) * 1987-12-21 1989-05-23 American Cyanamid Company Process for preparing 2-chloro-4,5-difluorobenzoic acid
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
EP0342849A3 (en) * 1988-05-19 1990-03-14 Pfizer Inc. Intermediates for preparing 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid esters
EP0345998A1 (en) * 1988-06-06 1989-12-13 Eli Lilly And Company Process and intermediates for beta-lactam antibiotics
US4883270A (en) * 1989-02-09 1989-11-28 Maag Henry H Four-bar variable-resistance frontal calf developing machine
RU2049777C1 (ru) * 1989-08-16 1995-12-10 Пфайзер Инк. Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения

Also Published As

Publication number Publication date
EP0449445A2 (en) 1991-10-02
NO911229D0 (no) 1991-03-26
YU53991A (sh) 1993-11-16
ZA912263B (en) 1992-11-25
CN1041083C (zh) 1998-12-09
US5380860A (en) 1995-01-10
KR930005059B1 (ko) 1993-06-15
IL97617A (en) 1998-08-16
IE910991A1 (en) 1991-10-09
EP0449445A3 (en) 1993-08-25
EG19607A (en) 1995-07-27
CA2039306A1 (en) 1991-09-28
JPH0648990A (ja) 1994-02-22
KR920018007A (ko) 1992-10-21
PH30994A (en) 1997-12-23
BR9101188A (pt) 1991-11-05
CA2039306C (en) 1999-01-26
IL97617A0 (en) 1992-06-21
MY108069A (en) 1996-08-15
NZ237555A (en) 1993-08-26
PL289582A1 (en) 1992-06-01
AU617066B1 (en) 1991-11-14
PT97130B (pt) 1999-02-26
NO911229L (no) 1991-09-30
HUT56826A (en) 1991-10-28
CN1055177A (zh) 1991-10-09
FI911465A (fi) 1991-09-28
RU2058977C1 (ru) 1996-04-27
FI911465A0 (fi) 1991-03-26

Similar Documents

Publication Publication Date Title
PT97433A (pt) Processo para a preparacao de sacarose-6-ester
PT93785A (pt) Processo para a preparacao de derivados de 3-substituido-2-oxindole
BR8802484A (pt) Processo para a preparacao de isocianatos
PT93452A (pt) Processo para a preparacao de uma pastilha de colestiramina
BR9005400A (pt) Processo para a preparacao de combinacoes de poliimidas
PT90293A (pt) Processo para a preparacao de macrolidos
BR9105370A (pt) Processo aperfeicoado para a preparacao de eteres glicidilicos
BR9007866A (pt) Processo para a obtencao hidrotermica de solucoes de silicato de potassio
PT90630A (pt) Processo para a preparacao de composicoes de psilio facilmente dispersiveis
PT90854A (pt) Processo para a preparacao de 1-aril-2-naftoilaminas
BR9001503A (pt) Processo para a preparacao de alquil-halogenossilanos
PT93629A (pt) Processo para a preparacao de derivados de tieno-triazolo-diazepina
PT89039A (pt) Processo para a preparacao de l-ramnose
BR8803678A (pt) Processo para a preparacao de polieteramidas
PT97130A (pt) Processo para a preparacao de beta-cetoesteres uteis na preparacao de antibioticos quinolona
PT96033A (pt) Processo para a preparacao de flocos
PT91716A (pt) Processo para a preparacao de antibioticos beta-lactamicos
PT97828A (pt) Processo para a preparacao de fenil-triazinas
BR8806351A (pt) Processo para a preparacao de fenil-ureias
PT94952A (pt) Processo para a preparacao de derivados peptidicos ciclicos antagonistas de neuroquinina a
PT93631A (pt) Processo para a preparacao de derivados de tieno-triazolo-diazepina
BR8902030A (pt) Processo para a preparacao de n-fosfonometilglicina
BR9005826A (pt) Processo para a preparacao de alcano-e arenosulfonamidas
BR9102040A (pt) Processo para a preparacao de tio-derivados de alquil-hidroxianilino-triazina
PT84656B (pt) Processo para a preparacao de antibioticos beta-lactamicos

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910724

FG3A Patent granted, date of granting

Effective date: 19981111

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20030531