NO910263L - Fremgangsmaate for fremstilling av di- og tetra-fluoranaloger av skualen. - Google Patents

Fremgangsmaate for fremstilling av di- og tetra-fluoranaloger av skualen.

Info

Publication number
NO910263L
NO910263L NO91910263A NO910263A NO910263L NO 910263 L NO910263 L NO 910263L NO 91910263 A NO91910263 A NO 91910263A NO 910263 A NO910263 A NO 910263A NO 910263 L NO910263 L NO 910263L
Authority
NO
Norway
Prior art keywords
tetra
fluor
analogues
school
procedure
Prior art date
Application number
NO91910263A
Other languages
English (en)
Other versions
NO910263D0 (no
Inventor
Esa Tero Jarvi
Michael Louis Edwards
James Ray Mccarthy
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO910263D0 publication Critical patent/NO910263D0/no
Publication of NO910263L publication Critical patent/NO910263L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C21/00—Acyclic unsaturated compounds containing halogen atoms
    • C07C21/02—Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds
    • C07C21/215—Halogenated polyenes with more than two carbon-to-carbon double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Pyrrole Compounds (AREA)
NO91910263A 1990-03-30 1991-01-23 Fremgangsmaate for fremstilling av di- og tetra-fluoranaloger av skualen. NO910263L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,203 US5011859A (en) 1990-03-30 1990-03-30 Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase

Publications (2)

Publication Number Publication Date
NO910263D0 NO910263D0 (no) 1991-01-23
NO910263L true NO910263L (no) 1991-10-01

Family

ID=23996803

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91910263A NO910263L (no) 1990-03-30 1991-01-23 Fremgangsmaate for fremstilling av di- og tetra-fluoranaloger av skualen.

Country Status (19)

Country Link
US (1) US5011859A (no)
EP (1) EP0448934B1 (no)
JP (1) JP2911239B2 (no)
KR (1) KR0162659B1 (no)
CN (1) CN1055172A (no)
AT (1) ATE118756T1 (no)
AU (1) AU629726B2 (no)
CA (1) CA2034612C (no)
DE (1) DE69107488T2 (no)
ES (1) ES2071131T3 (no)
FI (1) FI910425L (no)
HU (1) HU208103B (no)
IE (1) IE910181A1 (no)
IL (1) IL97356A0 (no)
NO (1) NO910263L (no)
NZ (1) NZ236800A (no)
PH (1) PH27365A (no)
PT (1) PT96654A (no)
ZA (1) ZA91392B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995004025A1 (en) * 1993-07-29 1995-02-09 Chugai Seiyaku Kabushiki Kaisha Tricarboxylic acid derivative having squalene synthetase inhibitor activity
DE19754795A1 (de) * 1997-12-10 1999-06-17 Boehringer Ingelheim Pharma Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
AR063275A1 (es) * 2006-10-12 2009-01-14 Epix Delaware Inc Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2.
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
WO2009076404A1 (en) * 2007-12-10 2009-06-18 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
BRPI0820701A2 (pt) 2007-12-11 2015-06-16 Cytopathfinder Inc Composto de carboxamida e seu uso como agonistas do receptor de quimiocina
US20130072519A1 (en) 2010-05-21 2013-03-21 Edward Lee Conn 2-phenyl benzoylamides
EP2680874A2 (en) 2011-03-04 2014-01-08 Pfizer Inc Edn3-like peptides and uses thereof
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
BR112021013807A2 (pt) 2019-01-18 2021-11-30 Astrazeneca Ab Inibidores de pcsk9 e seus métodos de uso
CN112678833B (zh) * 2020-11-17 2023-08-04 广西中烟工业有限责任公司 纳米二氧化硅改性角鲨烯有机硅颗粒及其制备和使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876672A (en) * 1972-02-21 1975-04-08 Du Pont Hydroformylation of olefins
DE2913677C2 (de) * 1979-04-05 1983-03-03 Union Rheinische Braunkohlen Kraftstoff AG, 5000 Köln Verfahren zur Herstellung von Acetaldehyddimethylacetal
US4455441A (en) * 1982-09-24 1984-06-19 Research Foundation Of State University Of New York Attractant termiticidal compounds, compositions and methods of use therefor
DE3618115A1 (de) * 1986-05-30 1987-12-03 Bayer Ag Halogenolefine
US4876295A (en) * 1987-03-11 1989-10-24 The Dow Chemical Company Flexible thermoplastic epoxy resin and coatings prepared therefrom

Also Published As

Publication number Publication date
FI910425A0 (fi) 1991-01-29
HUT56533A (en) 1991-09-30
AU6946891A (en) 1991-10-03
HU910174D0 (en) 1991-08-28
DE69107488T2 (de) 1995-06-14
FI910425A7 (fi) 1991-10-01
PT96654A (pt) 1991-10-31
PH27365A (en) 1993-06-21
DE69107488D1 (de) 1995-03-30
EP0448934A2 (en) 1991-10-02
CA2034612A1 (en) 1991-10-01
HU208103B (en) 1993-08-30
AU629726B2 (en) 1992-10-08
EP0448934A3 (en) 1991-11-27
ES2071131T3 (es) 1995-06-16
US5011859A (en) 1991-04-30
JP2911239B2 (ja) 1999-06-23
IL97356A0 (en) 1992-05-25
NZ236800A (en) 1993-05-26
CN1055172A (zh) 1991-10-09
NO910263D0 (no) 1991-01-23
KR910016660A (ko) 1991-11-05
ZA91392B (en) 1991-10-30
ATE118756T1 (de) 1995-03-15
CA2034612C (en) 2001-05-15
JPH04221327A (ja) 1992-08-11
KR0162659B1 (ko) 1999-01-15
FI910425L (fi) 1991-10-01
EP0448934B1 (en) 1995-02-22
IE910181A1 (en) 1991-10-09

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