NO893021L - Fremgangsmaate for fremstilling av en biologisk aktiv forbindelse, fr 901228. - Google Patents

Fremgangsmaate for fremstilling av en biologisk aktiv forbindelse, fr 901228.

Info

Publication number
NO893021L
NO893021L NO89893021A NO893021A NO893021L NO 893021 L NO893021 L NO 893021L NO 89893021 A NO89893021 A NO 89893021A NO 893021 A NO893021 A NO 893021A NO 893021 L NO893021 L NO 893021L
Authority
NO
Norway
Prior art keywords
substance
preparing
procedure
active compound
biological active
Prior art date
Application number
NO89893021A
Other languages
English (en)
Norwegian (no)
Other versions
NO893021D0 (no
Inventor
Masakuni Okuhara
Toshio Goto
Yasuhiro Hori
Takashi Fujita
Hirotsugu Ueda
Nobuharu Shigematsu
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO893021(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO893021D0 publication Critical patent/NO893021D0/no
Publication of NO893021L publication Critical patent/NO893021L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Reinforced Plastic Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
NO89893021A 1988-07-26 1989-07-25 Fremgangsmaate for fremstilling av en biologisk aktiv forbindelse, fr 901228. NO893021L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817743A GB8817743D0 (en) 1988-07-26 1988-07-26 Fr901228 substance & preparation thereof

Publications (2)

Publication Number Publication Date
NO893021D0 NO893021D0 (no) 1989-07-25
NO893021L true NO893021L (no) 1990-01-29

Family

ID=10641100

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89893021A NO893021L (no) 1988-07-26 1989-07-25 Fremgangsmaate for fremstilling av en biologisk aktiv forbindelse, fr 901228.

Country Status (16)

Country Link
US (1) US4977138A (fr)
EP (1) EP0352646B1 (fr)
JP (1) JPH0764872B2 (fr)
CN (1) CN1040054A (fr)
AT (1) ATE94561T1 (fr)
AU (1) AU3829089A (fr)
CA (1) CA1335083C (fr)
DE (1) DE68909139T2 (fr)
DK (1) DK366889A (fr)
ES (1) ES2058411T3 (fr)
FI (1) FI893359A (fr)
GB (1) GB8817743D0 (fr)
HU (1) HU211514A9 (fr)
IL (1) IL90949A0 (fr)
NO (1) NO893021L (fr)
ZA (1) ZA895121B (fr)

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JPH06247964A (ja) * 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
NZ335211A (en) * 1996-11-22 2000-02-28 Pioneer Hi Bred Int Micro-organism Ochrobactrum anthropi and method for degradation of moniliformin in grain
DK1142905T3 (da) * 1999-01-13 2006-09-18 Astellas Pharma Inc Hidtil ukendt depsipeptidforbindelse
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
KR20020062956A (ko) * 1999-12-08 2002-07-31 싸이트 테라피스 인코포레이티드 면역억제제로서 사용하기 위한 뎁시펩티드 및 이의 동류물
WO2002006307A1 (fr) * 2000-07-17 2002-01-24 Fujisawa Pharmaceutical Co., Ltd. Fk228 reduit et son utilisation
JP2004508049A (ja) * 2000-09-01 2004-03-18 藤沢薬品工業株式会社 Ｆｒ９０１２２８物質の製造法
ES2371630T3 (es) * 2001-08-21 2012-01-05 Astellas Pharma Inc. Uso medicinal de un inhibidor de histona desacetilasa y método para evaluar su efecto antitumoral.
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
CN1649645A (zh) * 2002-04-05 2005-08-03 藤泽药品工业株式会社 用于治疗肾癌的缩酚肽
CA2519320A1 (fr) * 2003-02-19 2004-09-02 Astellas Pharma Inc. Procede d'evaluation de l'effet antitumoral d'un inhibiteur d'histone desacetylase
DK2238982T3 (da) * 2003-06-27 2013-01-28 Astellas Pharma Inc Terapeutisk middel til blødt væv-sarcom
JP4779971B2 (ja) 2003-09-25 2011-09-28 アステラス製薬株式会社 ヒストンデアセチラーゼ阻害剤とトポイソメラーゼｉｉ阻害剤とからなる抗腫瘍剤
WO2005058298A2 (fr) * 2003-12-10 2005-06-30 Wisconsin Alumni Research Foundation Analogues de fk228 et methodes de production et d'utilisation desdits analogues
US20050187148A1 (en) * 2004-02-25 2005-08-25 Yoshinori Naoe Antitumor agent
US7951780B2 (en) * 2004-02-25 2011-05-31 Astellas Pharma Inc. Antitumor agent
WO2005115149A2 (fr) * 2004-05-20 2005-12-08 Dow Agrosciences Llc Activite insecticide d'un peptide cyclique
CA2586228A1 (fr) * 2004-11-17 2006-05-26 The University Of Chicago Inhibiteurs de l'histone desacetylase et leurs methodes d'utilisation
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
JP2009519224A (ja) * 2005-11-18 2009-05-14 グロスター ファーマシューティカルズ， インコーポレイテッド Ｈｄａｃインヒビターｆｋ２２８の代謝産物誘導体
WO2008013589A2 (fr) * 2006-04-24 2008-01-31 Gloucester Pharmaceuticals Traitement de tumeurs exprimant ras
US8957027B2 (en) * 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
EP2124990A4 (fr) 2006-12-29 2010-04-21 Gloucester Pharmaceuticals Inc Traitements du cancer à base de romidepsine
WO2008083288A2 (fr) * 2006-12-29 2008-07-10 Gloucester Pharmaceuticals Préparation de la romidepsine
WO2008098199A2 (fr) * 2007-02-08 2008-08-14 Uwm Research Foundation, Inc. Séquences utilisables pour la biosynthèse de fk228 et procédés de synthèse de fk228 et d'analogues de fk228
US20110060021A1 (en) * 2009-08-19 2011-03-10 Yiqiang Cheng Histone deacetylase inhibitors and uses thereof
AR080234A1 (es) * 2010-02-25 2012-03-21 Marrone Bio Innovations Inc Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo
RU2607634C2 (ru) 2010-07-12 2017-01-10 Селджин Корпорейшн Твердые формы ромидепсина и их применение
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
WO2013032693A2 (fr) * 2011-08-27 2013-03-07 Marrone Bio Innovations, Inc. Souche bactérienne isolée du gène burkholderia et métabolites pesticides dérivés de cette souche, formulations et utilisations
WO2013043967A1 (fr) 2011-09-23 2013-03-28 Celgene Corporation Romidepsine et 5-azacitidine pour l'utilisation dans le traitement d'un lymphome
JP2014526564A (ja) 2011-09-26 2014-10-06 セルジーン コーポレイション 化学療法抵抗性癌の併用療法
WO2013047509A1 (fr) 2011-09-30 2013-04-04 国立大学法人東北大学 Nouvel inhibiteur de phosphatidylinositol-3-kinase et composition pharmaceutique
WO2013085902A1 (fr) 2011-12-05 2013-06-13 The University Of Texas M.D. Procédés de polythérapie pour le traitement d'un cancer du sein inflammatoire
MX2014008390A (es) * 2012-01-12 2014-09-22 Celgene Corp Formulaciones de romidepsina y sus usos.
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
CN103877010B (zh) * 2012-12-21 2018-06-01 正大天晴药业集团股份有限公司 一种罗米地辛溶液的制备方法
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
EP3473615B1 (fr) 2013-02-28 2022-01-19 Journey Medical Corporation Sels de glycopyrrolate
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
CN103173390B (zh) * 2013-03-16 2014-09-10 浙江海正药业股份有限公司 一种紫色杆菌菌株及其应用
CN104072589B (zh) * 2013-03-29 2017-09-22 浙江海正药业股份有限公司 抗肿瘤三硫化合物及其制备方法与应用
CN104447950A (zh) * 2013-09-18 2015-03-25 上海医药工业研究院 一种罗米地辛的分离纯化方法
CN104450837B (zh) * 2013-09-18 2019-01-01 上海医药工业研究院 一种用于生产罗米地辛的方法及发酵培养基
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
WO2015136548A2 (fr) * 2014-03-04 2015-09-17 Concord Biotech Limited Procédé d'isolement de romidepsine à partir d'un bouillon de fermentation et de préparation de cristaux de romidepsine
CN104894195B (zh) * 2014-03-07 2018-11-13 上海医药工业研究院 一种提高fk228产量的发酵培养基
CN104262456B (zh) * 2014-09-11 2018-01-09 浙江海正药业股份有限公司 一种罗米地辛的新晶型及其制备方法和用途
EP3313420B1 (fr) 2015-06-25 2024-03-13 The Children's Medical Center Corporation Procédés et compositions se rapportant à l'expansion, l'enrichissement et la conservation de cellules souches hématopoïétiques
WO2017068596A1 (fr) * 2015-10-20 2017-04-27 Msn Laboratories Private Limited Procédé amélioré pour la préparation de (1s, 4s, 7z, 10s, 16e, 21r)- 7-éthylidène-4,21-bis(1-méthyléthyl)-2-oxa-12,13-dithia-5, 8, 20, 23- tétraazabicyclo[8.7.6]tricos-16-ène-3, 6, 9, 19, 22-pentone
WO2017161001A1 (fr) 2016-03-15 2017-09-21 Children's Medical Center Corporation Procédés et compositions concernant l'expansion de cellules souches hématopoïétiques
EP3893647A1 (fr) 2018-12-14 2021-10-20 Pioneer Hi-Bred International, Inc. Produits biologiques et leur utilisation chez des végétaux
WO2020139453A2 (fr) * 2018-12-24 2020-07-02 Marrone Bio Innovations, Inc. Méthode d'augmentation de production de romidepsine à partir d'un bouillon de fermentation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61101501A (ja) * 1984-10-24 1986-05-20 Yamanouchi Pharmaceut Co Ltd 制癌作用を有する多糖及びその製法
US4785078A (en) * 1985-04-18 1988-11-15 Pfizer Inc. Transformation product of thiosporamicin
EP0253245B1 (fr) * 1986-07-08 1992-10-14 Takeda Chemical Industries, Ltd. Peptides à activité biologique TAN-866
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics

Also Published As

Publication number Publication date
NO893021D0 (no) 1989-07-25
CN1040054A (zh) 1990-02-28
AU3829089A (en) 1990-02-01
CA1335083C (fr) 1995-04-04
EP0352646A3 (en) 1990-10-31
DE68909139D1 (de) 1993-10-21
FI893359A (fi) 1990-01-27
JPH0764872B2 (ja) 1995-07-12
DK366889D0 (da) 1989-07-25
ATE94561T1 (de) 1993-10-15
DK366889A (da) 1990-01-27
ES2058411T3 (es) 1994-11-01
GB8817743D0 (en) 1988-09-01
EP0352646A2 (fr) 1990-01-31
FI893359A0 (fi) 1989-07-11
EP0352646B1 (fr) 1993-09-15
IL90949A0 (en) 1990-02-09
DE68909139T2 (de) 1994-02-10
JPH0285296A (ja) 1990-03-26
US4977138A (en) 1990-12-11
ZA895121B (en) 1990-08-29
HU211514A9 (en) 1995-11-28

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