MX2014008390A - Formulaciones de romidepsina y sus usos. - Google Patents

Formulaciones de romidepsina y sus usos.

Info

Publication number
MX2014008390A
MX2014008390A MX2014008390A MX2014008390A MX2014008390A MX 2014008390 A MX2014008390 A MX 2014008390A MX 2014008390 A MX2014008390 A MX 2014008390A MX 2014008390 A MX2014008390 A MX 2014008390A MX 2014008390 A MX2014008390 A MX 2014008390A
Authority
MX
Mexico
Prior art keywords
romidepsin
formulations
romidepsin formulations
mannitol
formulation
Prior art date
Application number
MX2014008390A
Other languages
English (en)
Inventor
Ho-Wah Hui
Lianfeng Huang Iii
Victor Peykov
Willard R Foss
Vijay Naringrekar
Mei Lai
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of MX2014008390A publication Critical patent/MX2014008390A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15Depsipeptides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se proporcionan en la presente las formulaciones de Romidepsina. También se proporcionan los métodos para producir estas formulaciones, y sus usos. En una modalidad, la formulación es una combinación de Romidepsina y manitol.
MX2014008390A 2012-01-12 2013-01-11 Formulaciones de romidepsina y sus usos. MX2014008390A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261586066P 2012-01-12 2012-01-12
PCT/US2013/021212 WO2013106696A1 (en) 2012-01-12 2013-01-11 Romidepsin formulations and uses thereof

Publications (1)

Publication Number Publication Date
MX2014008390A true MX2014008390A (es) 2014-09-22

Family

ID=47604232

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014008390A MX2014008390A (es) 2012-01-12 2013-01-11 Formulaciones de romidepsina y sus usos.

Country Status (8)

Country Link
US (3) US20130184225A1 (es)
EP (1) EP2802340B1 (es)
JP (1) JP6170946B2 (es)
CN (1) CN104168908A (es)
AU (1) AU2013201937B8 (es)
CA (1) CA2863291A1 (es)
MX (1) MX2014008390A (es)
WO (1) WO2013106696A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
CN106137980B (zh) * 2015-03-31 2021-04-13 深圳翰宇药业股份有限公司 一种罗米地辛脂微球制剂及其制备方法
WO2016210292A1 (en) 2015-06-25 2016-12-29 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
EP4049665A1 (en) 2016-03-15 2022-08-31 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion
EP3773488A4 (en) * 2018-04-05 2021-11-17 Tarveda Therapeutics, Inc. PHARMACEUTICAL COMPOSITIONS WITH A REDUCED TERT-BUTANOL CONTENT

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8817743D0 (en) * 1988-07-26 1988-09-01 Fujisawa Pharmaceutical Co Fr901228 substance & preparation thereof
JPH0764872A (ja) 1993-08-26 1995-03-10 Fujitsu Ten Ltd データ記憶制御装置
US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
RU2250763C2 (ru) * 1999-03-03 2005-04-27 Эли Лилли Энд Компани Фармацевтические препараты эхинокандина, содержащие мицелообразующие поверхностно-активные вещества
US7396665B2 (en) 2000-09-01 2008-07-08 Astellas Pharma, Inc. Method of producing FR901228
PT2238982E (pt) * 2003-06-27 2013-01-22 Astellas Pharma Inc Agente terapêutico para o sarcoma de tecidos moles
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
EP2040731A4 (en) * 2006-06-09 2010-05-19 Merrion Res Iii Ltd SOLID DOSAGE FORM FOR ORAL ADMINISTRATION CONTAINING AN ACTIVATOR
EP2450049A1 (en) * 2006-12-29 2012-05-09 Gloucester Pharmaceuticals, Inc. Romidepsin-based treatments for cancer
WO2008127659A2 (en) * 2007-04-13 2008-10-23 University Of Texas Southwestern Medical Center Combination therapy for cancer
JP2010105965A (ja) * 2008-10-30 2010-05-13 Taiyo Yakuhin Kogyo Kk バンコマイシン製剤
MX2012005993A (es) * 2009-11-23 2012-11-23 Cubist Pharm Inc Composiciones de lipopeptido y metodos relacionados.
CN103108648A (zh) 2010-07-12 2013-05-15 细胞基因公司 罗米地辛固体形式及其用途

Also Published As

Publication number Publication date
JP2015503623A (ja) 2015-02-02
US20130184225A1 (en) 2013-07-18
EP2802340A1 (en) 2014-11-19
EP2802340B1 (en) 2020-10-28
JP6170946B2 (ja) 2017-07-26
AU2013201937B8 (en) 2015-08-20
AU2013201937A1 (en) 2013-08-01
AU2013201937A8 (en) 2015-08-20
WO2013106696A1 (en) 2013-07-18
CN104168908A (zh) 2014-11-26
CA2863291A1 (en) 2013-07-18
AU2013201937B2 (en) 2015-07-30
US20160367625A1 (en) 2016-12-22
US20150051157A1 (en) 2015-02-19

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