IL90949A0 - Fr901228 substance,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Fr901228 substance,processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL90949A0
IL90949A0 IL90949A IL9094989A IL90949A0 IL 90949 A0 IL90949 A0 IL 90949A0 IL 90949 A IL90949 A IL 90949A IL 9094989 A IL9094989 A IL 9094989A IL 90949 A0 IL90949 A0 IL 90949A0
Authority
IL
Israel
Prior art keywords
substance
pharmaceutical compositions
processes
preparation
same
Prior art date
Application number
IL90949A
Other languages
English (en)
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL90949(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IL90949A0 publication Critical patent/IL90949A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Reinforced Plastic Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
IL90949A 1988-07-26 1989-07-12 Fr901228 substance,processes for the preparation thereof and pharmaceutical compositions containing the same IL90949A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817743A GB8817743D0 (en) 1988-07-26 1988-07-26 Fr901228 substance & preparation thereof

Publications (1)

Publication Number Publication Date
IL90949A0 true IL90949A0 (en) 1990-02-09

Family

ID=10641100

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90949A IL90949A0 (en) 1988-07-26 1989-07-12 Fr901228 substance,processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (16)

Country Link
US (1) US4977138A (xx)
EP (1) EP0352646B1 (xx)
JP (1) JPH0764872B2 (xx)
CN (1) CN1040054A (xx)
AT (1) ATE94561T1 (xx)
AU (1) AU3829089A (xx)
CA (1) CA1335083C (xx)
DE (1) DE68909139T2 (xx)
DK (1) DK366889A (xx)
ES (1) ES2058411T3 (xx)
FI (1) FI893359A (xx)
GB (1) GB8817743D0 (xx)
HU (1) HU211514A9 (xx)
IL (1) IL90949A0 (xx)
NO (1) NO893021L (xx)
ZA (1) ZA895121B (xx)

Families Citing this family (55)

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US5130414A (en) * 1989-11-30 1992-07-14 Arizona Board Of Regents, A Body Corporate Of Arizona State University Isolation and structural elucidation of the cyclic peptide hymenistatin 1
JPH06247964A (ja) * 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
CA2272554C (en) * 1996-11-22 2001-08-28 Pioneer Hi-Bred International, Inc. Moniliformin detoxification compositions and methods
PT1142905E (pt) 1999-01-13 2006-10-31 Astellas Pharma Inc Novo composto de depsipeptido
BR0016154A (pt) 1999-12-08 2003-02-25 Xcyte Therapies Inc Depsipeptida e seus congêneres papa uso como imunossupressores
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
DE60137932D1 (de) * 2000-07-17 2009-04-23 Astellas Pharma Inc Reduziertes fk228 und seine verwendung
WO2002020817A1 (en) 2000-09-01 2002-03-14 Fujisawa Pharmaceutical Co., Ltd. A method of producing fr901228
CA2457043A1 (en) * 2001-08-21 2003-02-27 Fujisawa Pharmaceutical Co., Ltd. Medicinal use of histone deacetylase inhibitor and method of evaluating antitumor effect thereof
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
EP1492596A1 (en) * 2002-04-05 2005-01-05 Fujisawa Pharmaceutical Co., Ltd. Depsipeptide for therapy of kidney cancer
JPWO2004074478A1 (ja) * 2003-02-19 2006-06-01 アステラス製薬株式会社 ヒストンデアセチラーゼ阻害剤の抗腫瘍効果の予測方法
PL2238982T3 (pl) * 2003-06-27 2013-03-29 Astellas Pharma Inc Środek do terapii mięsaka tkanek miękkich
ES2425083T3 (es) 2003-09-25 2013-10-11 Astellas Pharma Inc. Agente antitumoral que comprende FK228 como inhibidor de histona desacetilasa y doxorrubicina como inhibidor de topoisomerasa II
WO2005058298A2 (en) * 2003-12-10 2005-06-30 Wisconsin Alumni Research Foundation Fk228 analogs and their use as hdac-inhibitors
US20050187148A1 (en) * 2004-02-25 2005-08-25 Yoshinori Naoe Antitumor agent
US7951780B2 (en) * 2004-02-25 2011-05-31 Astellas Pharma Inc. Antitumor agent
WO2005115149A2 (en) * 2004-05-20 2005-12-08 Dow Agrosciences Llc Insectidal activity of a cyclic peptide
CA2586228A1 (en) * 2004-11-17 2006-05-26 The University Of Chicago Histone deacetylase inhibitors and methods of use
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
US20070129290A1 (en) * 2005-11-18 2007-06-07 Or Yat S Metabolite derivatives of the HDAC inhibitor FK228
EP2012801A4 (en) * 2006-04-24 2009-08-05 Gloucester Pharmaceuticals Inc GEMCITABINE COMBINATION THERAPY
WO2007146730A2 (en) 2006-06-08 2007-12-21 Gloucester Pharmaceuticals Deacetylase inhibitor therapy
EP2124990A4 (en) 2006-12-29 2010-04-21 Gloucester Pharmaceuticals Inc TUMOR TREATMENT BASED ON ROMIDEPSIN
CN101801994A (zh) * 2006-12-29 2010-08-11 格洛斯特制药公司 制备Romidepsin
WO2008098199A2 (en) * 2007-02-08 2008-08-14 Uwm Research Foundation, Inc. Sequences for fk228 biosyntnesis and methods of synthesizing fk228 and fk228 analogs
US20110060021A1 (en) * 2009-08-19 2011-03-10 Yiqiang Cheng Histone deacetylase inhibitors and uses thereof
AR080234A1 (es) * 2010-02-25 2012-03-21 Marrone Bio Innovations Inc Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo
CA2804795A1 (en) 2010-07-12 2012-01-19 Nicholas Vrolijk Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
KR101632806B1 (ko) * 2011-08-27 2016-06-23 마론 바이오 이노베이션스, 인코포레이티드 부르크홀데리아 속의 단리된 박테리아 균주 및 그로부터의 살충 대사물-제제 및 용도
EP2758067A1 (en) 2011-09-23 2014-07-30 Celgene Corporation Romidepsin and 5 - azacitidine for use in treating lymphoma
KR20140069271A (ko) 2011-09-26 2014-06-09 셀진 코포레이션 화학요법 내성 암에 대한 병용 요법
WO2013047509A1 (ja) 2011-09-30 2013-04-04 国立大学法人東北大学 新規ホスファチジルイノシトール３キナーゼ阻害剤及び医薬組成物
WO2013085902A1 (en) 2011-12-05 2013-06-13 The University Of Texas M.D. Combination therapy methods for treating an inflammatory breast cancer
MX2014008390A (es) 2012-01-12 2014-09-22 Celgene Corp Formulaciones de romidepsina y sus usos.
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
CN103877010B (zh) * 2012-12-21 2018-06-01 正大天晴药业集团股份有限公司 一种罗米地辛溶液的制备方法
KR20150119468A (ko) 2013-02-28 2015-10-23 더미라, 인코포레이티드 글리코피롤레이트 염
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
CN103173390B (zh) * 2013-03-16 2014-09-10 浙江海正药业股份有限公司 一种紫色杆菌菌株及其应用
CN104072589B (zh) * 2013-03-29 2017-09-22 浙江海正药业股份有限公司 抗肿瘤三硫化合物及其制备方法与应用
CN104447950A (zh) * 2013-09-18 2015-03-25 上海医药工业研究院 一种罗米地辛的分离纯化方法
CN104450837B (zh) * 2013-09-18 2019-01-01 上海医药工业研究院 一种用于生产罗米地辛的方法及发酵培养基
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
US10294276B2 (en) * 2014-03-04 2019-05-21 Concord Biotech Limited Process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin
CN104894195B (zh) * 2014-03-07 2018-11-13 上海医药工业研究院 一种提高fk228产量的发酵培养基
CN104262456B (zh) * 2014-09-11 2018-01-09 浙江海正药业股份有限公司 一种罗米地辛的新晶型及其制备方法和用途
JP6980534B2 (ja) 2015-06-25 2021-12-15 ザ チルドレンズ メディカル センター コーポレーション 造血幹細胞の増大、富化、および維持に関する方法および組成物
US10562931B2 (en) * 2015-10-20 2020-02-18 Msn Laboratories Private Limited Process for the preparation of (1S, 4S, 7Z, 10S, 16E, 21R)-7-ethyldene-4,21-bis(1-methyl-ethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone
AU2017235461B2 (en) 2016-03-15 2023-02-23 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion
WO2020123242A1 (en) 2018-12-14 2020-06-18 Pioneer Hi-Bred International, Inc. Biologicals and their use in plants
EP3902908A4 (en) * 2018-12-24 2024-01-03 Pro Farm Group, Inc. METHOD FOR INCREASING PRODUCTION OF ROMIDEPSIN FROM A FERMENTATION BROTH

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61101501A (ja) * 1984-10-24 1986-05-20 Yamanouchi Pharmaceut Co Ltd 制癌作用を有する多糖及びその製法
US4785078A (en) * 1985-04-18 1988-11-15 Pfizer Inc. Transformation product of thiosporamicin
EP0253245B1 (en) * 1986-07-08 1992-10-14 Takeda Chemical Industries, Ltd. Biologically active peptides tan-866
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics

Also Published As

Publication number Publication date
DK366889D0 (da) 1989-07-25
GB8817743D0 (en) 1988-09-01
NO893021D0 (no) 1989-07-25
CN1040054A (zh) 1990-02-28
CA1335083C (en) 1995-04-04
US4977138A (en) 1990-12-11
JPH0764872B2 (ja) 1995-07-12
ES2058411T3 (es) 1994-11-01
EP0352646B1 (en) 1993-09-15
JPH0285296A (ja) 1990-03-26
EP0352646A2 (en) 1990-01-31
FI893359A0 (fi) 1989-07-11
HU211514A9 (en) 1995-11-28
EP0352646A3 (en) 1990-10-31
ATE94561T1 (de) 1993-10-15
AU3829089A (en) 1990-02-01
DE68909139T2 (de) 1994-02-10
FI893359A (fi) 1990-01-27
NO893021L (no) 1990-01-29
DE68909139D1 (de) 1993-10-21
DK366889A (da) 1990-01-27
ZA895121B (en) 1990-08-29

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Legal Events

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