DK366889A - Peptidderivat - Google Patents

Peptidderivat Download PDF

Info

Publication number
DK366889A
DK366889A DK366889A DK366889A DK366889A DK 366889 A DK366889 A DK 366889A DK 366889 A DK366889 A DK 366889A DK 366889 A DK366889 A DK 366889A DK 366889 A DK366889 A DK 366889A
Authority
DK
Denmark
Prior art keywords
peptide
ferm
chem
substance
production
Prior art date
Application number
DK366889A
Other languages
English (en)
Other versions
DK366889D0 (da
Inventor
Masakuni Okuhara
Toshio Goto
Yasuhiro Hori
Takashi Fujita
Hirotsugu Ueda
Nobuharu Shigematsu
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK366889(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK366889D0 publication Critical patent/DK366889D0/da
Publication of DK366889A publication Critical patent/DK366889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DK366889A 1988-07-26 1989-07-25 Peptidderivat DK366889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817743A GB8817743D0 (en) 1988-07-26 1988-07-26 Fr901228 substance & preparation thereof

Publications (2)

Publication Number Publication Date
DK366889D0 DK366889D0 (da) 1989-07-25
DK366889A true DK366889A (da) 1990-01-27

Family

ID=10641100

Family Applications (1)

Application Number Title Priority Date Filing Date
DK366889A DK366889A (da) 1988-07-26 1989-07-25 Peptidderivat

Country Status (16)

Country Link
US (1) US4977138A (da)
EP (1) EP0352646B1 (da)
JP (1) JPH0764872B2 (da)
CN (1) CN1040054A (da)
AT (1) ATE94561T1 (da)
AU (1) AU3829089A (da)
CA (1) CA1335083C (da)
DE (1) DE68909139T2 (da)
DK (1) DK366889A (da)
ES (1) ES2058411T3 (da)
FI (1) FI893359A (da)
GB (1) GB8817743D0 (da)
HU (1) HU211514A9 (da)
IL (1) IL90949A0 (da)
NO (1) NO893021L (da)
ZA (1) ZA895121B (da)

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JPH06247964A (ja) * 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
NZ335211A (en) * 1996-11-22 2000-02-28 Pioneer Hi Bred Int Micro-organism Ochrobactrum anthropi and method for degradation of moniliformin in grain
JP3554707B2 (ja) * 1999-01-13 2004-08-18 山之内製薬株式会社 新規デプシペプチド化合物
ES2225282T3 (es) * 1999-12-08 2005-03-16 Xcyte Therapies, Inc. Depsipeptido y congeneres del mismo para usar como inmunosupresores.
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
ATE425177T1 (de) * 2000-07-17 2009-03-15 Astellas Pharma Inc Reduziertes fk228 und seine verwendung
JP2004508049A (ja) 2000-09-01 2004-03-18 藤沢薬品工業株式会社 Ｆｒ９０１２２８物質の製造法
JP4238728B2 (ja) * 2001-08-21 2009-03-18 アステラス製薬株式会社 ヒストンデアセチラーゼ阻害剤の医薬用途ならびにその抗腫瘍効果の評価方法
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
JP2005521737A (ja) * 2002-04-05 2005-07-21 藤沢薬品工業株式会社 腎臓癌の治療のためのデプシペプチド
JPWO2004074478A1 (ja) * 2003-02-19 2006-06-01 アステラス製薬株式会社 ヒストンデアセチラーゼ阻害剤の抗腫瘍効果の予測方法
ES2397079T3 (es) * 2003-06-27 2013-03-04 Astellas Pharma Inc. Agente terapéutico para sarcoma de tejidos blandos
EP2263694B1 (en) * 2003-09-25 2013-06-12 Astellas Pharma Inc. Antitumor agent comprising the histone deacetylase inhibitor FK228 and the topoisomerase II inhibitor doxorubicin
EP1713460A2 (en) * 2003-12-10 2006-10-25 Wisconsin Alumni Research Foundation Fk228 analogs and their use as hdac-inhibitors
US20050187148A1 (en) * 2004-02-25 2005-08-25 Yoshinori Naoe Antitumor agent
US7951780B2 (en) * 2004-02-25 2011-05-31 Astellas Pharma Inc. Antitumor agent
US20050261174A1 (en) * 2004-05-20 2005-11-24 Paul Lewer Insecticidal activity of a cyclic peptide
AU2005307814A1 (en) * 2004-11-17 2006-05-26 The University Of Chicago Histone deacetylase inhibitors and methods of use
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
EP1965824A4 (en) * 2005-11-18 2011-10-19 Gloucester Pharmaceuticals Inc METABOLITENE DERIVATIVES OF HDAC INHIBITOR FK228
EP2012801A4 (en) * 2006-04-24 2009-08-05 Gloucester Pharmaceuticals Inc GEMCITABINE COMBINATION THERAPY
US8957027B2 (en) * 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
CN101801994A (zh) * 2006-12-29 2010-08-11 格洛斯特制药公司 制备Romidepsin
CN101687010A (zh) 2006-12-29 2010-03-31 格洛斯特制药公司 制备Romidepsin
WO2008098199A2 (en) * 2007-02-08 2008-08-14 Uwm Research Foundation, Inc. Sequences for fk228 biosyntnesis and methods of synthesizing fk228 and fk228 analogs
US20110060021A1 (en) * 2009-08-19 2011-03-10 Yiqiang Cheng Histone deacetylase inhibitors and uses thereof
AR080234A1 (es) 2010-02-25 2012-03-21 Marrone Bio Innovations Inc Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo
MY185130A (en) 2010-07-12 2021-04-30 Celgene Corp Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
BR112014004386A2 (pt) * 2011-08-27 2017-03-21 Marrone Bio Innovations Inc cepa bacteriana isolada do gênero burkholderia e formulações e usos como pesticida de seus metabólitos
EP2758067A1 (en) 2011-09-23 2014-07-30 Celgene Corporation Romidepsin and 5 - azacitidine for use in treating lymphoma
MX2014003591A (es) 2011-09-26 2014-09-08 Celgene Corp Terapia de combinacion para canceres quimiorresistentes.
EP2762148B1 (en) 2011-09-30 2017-12-27 Tohoku University Depsipeptide as phosphatidylinositol-3-kinase inhibitor and use thereof for treating cancer
WO2013085902A1 (en) 2011-12-05 2013-06-13 The University Of Texas M.D. Combination therapy methods for treating an inflammatory breast cancer
JP6170946B2 (ja) * 2012-01-12 2017-07-26 セルジーン コーポレイション ロミデプシン製剤及びその使用
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
CN103877010B (zh) * 2012-12-21 2018-06-01 正大天晴药业集团股份有限公司 一种罗米地辛溶液的制备方法
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
EP2961734B1 (en) 2013-02-28 2018-09-26 Dermira, Inc. Glycopyrrolate salts
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
CN103173390B (zh) * 2013-03-16 2014-09-10 浙江海正药业股份有限公司 一种紫色杆菌菌株及其应用
CN104072589B (zh) * 2013-03-29 2017-09-22 浙江海正药业股份有限公司 抗肿瘤三硫化合物及其制备方法与应用
CN104447950A (zh) * 2013-09-18 2015-03-25 上海医药工业研究院 一种罗米地辛的分离纯化方法
CN104450837B (zh) * 2013-09-18 2019-01-01 上海医药工业研究院 一种用于生产罗米地辛的方法及发酵培养基
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
IN2014MU00740A (da) * 2014-03-04 2015-09-25 Concord Biotech Ltd
CN104894195B (zh) * 2014-03-07 2018-11-13 上海医药工业研究院 一种提高fk228产量的发酵培养基
CN104262456B (zh) * 2014-09-11 2018-01-09 浙江海正药业股份有限公司 一种罗米地辛的新晶型及其制备方法和用途
EP3313420B1 (en) 2015-06-25 2024-03-13 The Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
US10562931B2 (en) * 2015-10-20 2020-02-18 Msn Laboratories Private Limited Process for the preparation of (1S, 4S, 7Z, 10S, 16E, 21R)-7-ethyldene-4,21-bis(1-methyl-ethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone
EP3429603B1 (en) 2016-03-15 2021-12-29 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion
WO2020123242A1 (en) 2018-12-14 2020-06-18 Pioneer Hi-Bred International, Inc. Biologicals and their use in plants
EP3902908A4 (en) * 2018-12-24 2024-01-03 Pro Farm Group Inc METHOD FOR INCREASING PRODUCTION OF ROMIDEPSIN FROM A FERMENTATION BROTH

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61101501A (ja) * 1984-10-24 1986-05-20 Yamanouchi Pharmaceut Co Ltd 制癌作用を有する多糖及びその製法
WO1986006065A1 (en) * 1985-04-18 1986-10-23 Pfizer Inc. Transformation product of thiosporamicin
DE3782199T2 (de) * 1986-07-08 1993-02-25 Takeda Chemical Industries Ltd Biologisch aktive peptide tan-866.
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics

Also Published As

Publication number Publication date
DE68909139T2 (de) 1994-02-10
EP0352646B1 (en) 1993-09-15
EP0352646A3 (en) 1990-10-31
NO893021L (no) 1990-01-29
IL90949A0 (en) 1990-02-09
JPH0285296A (ja) 1990-03-26
DE68909139D1 (de) 1993-10-21
CN1040054A (zh) 1990-02-28
ZA895121B (en) 1990-08-29
JPH0764872B2 (ja) 1995-07-12
NO893021D0 (no) 1989-07-25
HU211514A9 (en) 1995-11-28
FI893359A0 (fi) 1989-07-11
EP0352646A2 (en) 1990-01-31
ES2058411T3 (es) 1994-11-01
FI893359A (fi) 1990-01-27
DK366889D0 (da) 1989-07-25
ATE94561T1 (de) 1993-10-15
AU3829089A (en) 1990-02-01
GB8817743D0 (en) 1988-09-01
CA1335083C (en) 1995-04-04
US4977138A (en) 1990-12-11

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AHB Application shelved due to non-payment