NO883275D0 - Antibiotiske forbindelser. - Google Patents

Antibiotiske forbindelser.

Info

Publication number
NO883275D0
NO883275D0 NO883275A NO883275A NO883275D0 NO 883275 D0 NO883275 D0 NO 883275D0 NO 883275 A NO883275 A NO 883275A NO 883275 A NO883275 A NO 883275A NO 883275 D0 NO883275 D0 NO 883275D0
Authority
NO
Norway
Prior art keywords
het
ring
group
chem
hydroxy
Prior art date
Application number
NO883275A
Other languages
English (en)
Other versions
NO883275L (no
Inventor
Jean Claude Arnould
Dominique Boucherot
Frederick Henri Jung
David Huw Davies
Colin John Strawson
Original Assignee
Ici Plc
Ici Pharma Le Galien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc, Ici Pharma Le Galien filed Critical Ici Plc
Publication of NO883275D0 publication Critical patent/NO883275D0/no
Publication of NO883275L publication Critical patent/NO883275L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/40—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Threshing Machine Elements (AREA)
  • Revetment (AREA)
  • Pit Excavations, Shoring, Fill Or Stabilisation Of Slopes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
NO88883275A 1987-07-23 1988-07-22 Antibiotiske forbindelser. NO883275L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87401718 1987-07-23

Publications (2)

Publication Number Publication Date
NO883275D0 true NO883275D0 (no) 1988-07-22
NO883275L NO883275L (no) 1989-01-24

Family

ID=8198237

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88883275A NO883275L (no) 1987-07-23 1988-07-22 Antibiotiske forbindelser.

Country Status (16)

Country Link
US (1) US5019570A (no)
EP (1) EP0304158B1 (no)
JP (1) JPH0193592A (no)
KR (1) KR890002186A (no)
CN (1) CN1031378A (no)
AT (1) ATE107651T1 (no)
AU (1) AU1976288A (no)
DE (1) DE3850321T2 (no)
DK (1) DK414888A (no)
FI (1) FI883439A (no)
GB (1) GB8816519D0 (no)
HU (1) HU201949B (no)
NO (1) NO883275L (no)
NZ (1) NZ225533A (no)
PT (1) PT88070B (no)
ZA (1) ZA885271B (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232918A (en) * 1987-07-23 1993-08-03 Imperial Chemical Industries Plc Cephalosporin derivatives
GB8811056D0 (en) * 1988-05-10 1988-06-15 Ici Plc Antibiotic compounds
GB8811055D0 (en) * 1988-05-10 1988-06-15 Ici Plc Antibiotic compounds
ATE113953T1 (de) * 1988-05-10 1994-11-15 Ici Plc Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate.
US5149803A (en) * 1988-05-10 1992-09-22 Imperial Chemical Industries Plc Intermediates for cephalosporin compounds
US4904775A (en) * 1988-05-16 1990-02-27 E. R. Squibb & Sons, Inc. Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5273973A (en) * 1988-10-24 1993-12-28 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl esters
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
EP0366193A3 (en) * 1988-10-24 1992-01-08 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial quinolonyl lactams
CA2001203C (en) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Novel antimicrobial dithiocarbamoyl quinolones
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
CA2024282A1 (en) * 1989-09-21 1991-03-22 Peter H. Ermann Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics
JPH05506033A (ja) 1990-04-18 1993-09-02 ノーウィッチ、イートン、ファーマスーティカルズ、インコーポレーテッド 抗微生物性キノロニルラクタム類
US5234920A (en) * 1990-08-23 1993-08-10 Bristol-Myers Squibb Company Antibiotic C-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
ZA918014B (en) * 1990-11-05 1992-07-29 Squibb & Sons Inc Heteroaroyl derivatives of monocyclic beta-lactam antibiotics
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
DE69418218T2 (de) * 1994-02-25 1999-11-04 Aranda Lab Sa De Cv Chinolonylcarboxamidocephalosporin-derivate und diese enthaltende arzneimittel
RU2220960C2 (ru) * 1997-12-22 2004-01-10 Фармация Энд Апджон Компани 4-гидрокси-3-хинолинкарбоксамиды и гидразиды, фармацевтическая композиция и способ лечения на их основе
FI20001593A (fi) 2000-07-03 2002-01-04 Orion Yhtymo Oyj Comt-entsyymiõ inhiboivaa aktiivisuutta omaavia kumariinijohdannaisia
AU2005238386A1 (en) 2004-04-30 2005-11-10 Takeda Pharmaceutical Company Limited Heterocyclic amide compound and use thereof as an MMP-13 inhibitor
FR2873695A1 (fr) * 2004-07-30 2006-02-03 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien
FR2874922A1 (fr) * 2004-07-30 2006-03-10 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
JP2008508243A (ja) * 2004-07-30 2008-03-21 パルメド・ソシエテ・アノニム アミノキノリンをｑとし、抗生物質残基をａとする混成分子ｑａ、その合成及び抗菌剤としての使用
WO2009100250A1 (en) 2008-02-05 2009-08-13 Fibrogen, Inc. Chromene derivatives and use thereof as hif hydroxylase activity inhibitors
EP2370422B1 (en) 2008-11-14 2019-06-05 Fibrogen, Inc. Thiochromene derivatives as hif hydroxylase inhibitors
US20130065922A1 (en) * 2010-05-21 2013-03-14 Syngenta Crop Protection Llc Novel amides as fungicides
TWI547496B (zh) 2011-10-04 2016-09-01 葛蘭素集團公司 抗菌化合物
UY35103A (es) 2012-10-29 2014-05-30 Glaxo Group Ltd Compuestos de cefem 2-sustituidos
EP2934498B1 (en) * 2012-12-21 2017-11-15 Janssen Sciences Ireland UC Antibacterial compounds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5718689A (en) * 1980-07-08 1982-01-30 Eisai Co Ltd 7alpha-methoxycephem derivative
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
JPS57165389A (en) * 1981-04-02 1982-10-12 Eisai Co Ltd Novel penicillin and cephalosporin compound
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
US4552891A (en) * 1983-09-13 1985-11-12 Eli Lilly And Company Benzothiophene derivatives
JPS6064986A (ja) * 1983-09-20 1985-04-13 Toyama Chem Co Ltd セファロスポリン類の製造法
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
EP0182210B1 (en) * 1984-11-12 1991-02-27 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives
EP0187456A1 (en) * 1984-11-29 1986-07-16 Ici Pharma Cephalosporin derivatives
CA1267647A (en) * 1984-12-27 1990-04-10 Ryosuke Ushijima Cephalosporin derivatives
JPS6251688A (ja) * 1985-08-30 1987-03-06 Taito Pfizer Kk 新規なセフアロスポリン化合物
JPS62209082A (ja) * 1986-03-11 1987-09-14 Banyu Pharmaceut Co Ltd セフアロスポリン誘導体
EP0238060B1 (en) * 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
EP0241901B1 (en) * 1986-04-14 1994-08-24 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
EP0265185A3 (en) * 1986-10-21 1990-03-28 Beecham Group Plc Cephalosporins, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
CN1031378A (zh) 1989-03-01
ZA885271B (en) 1989-03-29
DK414888A (da) 1989-01-24
NZ225533A (en) 1990-12-21
EP0304158B1 (en) 1994-06-22
JPH0193592A (ja) 1989-04-12
US5019570A (en) 1991-05-28
GB8816519D0 (en) 1988-08-17
HU201949B (en) 1991-01-28
PT88070A (pt) 1989-06-30
DE3850321T2 (de) 1994-10-06
DK414888D0 (da) 1988-07-22
FI883439A (fi) 1989-01-24
FI883439A0 (fi) 1988-07-20
ATE107651T1 (de) 1994-07-15
PT88070B (pt) 1995-03-01
NO883275L (no) 1989-01-24
EP0304158A1 (en) 1989-02-22
DE3850321D1 (de) 1994-07-28
KR890002186A (ko) 1989-04-08
HUT47942A (en) 1989-04-28
AU1976288A (en) 1989-01-27

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