NO872095L - Immunologisk maalemetode og -sett. - Google Patents
Immunologisk maalemetode og -sett.Info
- Publication number
- NO872095L NO872095L NO872095A NO872095A NO872095L NO 872095 L NO872095 L NO 872095L NO 872095 A NO872095 A NO 872095A NO 872095 A NO872095 A NO 872095A NO 872095 L NO872095 L NO 872095L
- Authority
- NO
- Norway
- Prior art keywords
- treated
- cells
- porous matrix
- progesterone
- antibody
- Prior art date
Links
- 230000001900 immune effect Effects 0.000 title claims description 21
- 238000000691 measurement method Methods 0.000 title description 18
- 210000004027 cell Anatomy 0.000 claims abstract description 219
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims abstract description 174
- 239000011159 matrix material Substances 0.000 claims abstract description 169
- 239000000186 progesterone Substances 0.000 claims abstract description 88
- 229960003387 progesterone Drugs 0.000 claims abstract description 88
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 85
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 85
- 238000000034 method Methods 0.000 claims abstract description 67
- 239000012530 fluid Substances 0.000 claims abstract description 30
- 241001465754 Metazoa Species 0.000 claims abstract description 26
- 210000001124 body fluid Anatomy 0.000 claims abstract description 21
- 239000010839 body fluid Substances 0.000 claims abstract description 21
- 230000027455 binding Effects 0.000 claims abstract description 18
- 210000004369 blood Anatomy 0.000 claims abstract description 13
- 239000008280 blood Substances 0.000 claims abstract description 13
- 210000004080 milk Anatomy 0.000 claims abstract description 13
- 239000008267 milk Substances 0.000 claims abstract description 13
- 235000013336 milk Nutrition 0.000 claims abstract description 13
- 238000011534 incubation Methods 0.000 claims abstract description 11
- 210000002381 plasma Anatomy 0.000 claims abstract description 8
- 210000003296 saliva Anatomy 0.000 claims abstract description 5
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 87
- 239000000872 buffer Substances 0.000 claims description 64
- 239000011780 sodium chloride Substances 0.000 claims description 61
- 102000004190 Enzymes Human genes 0.000 claims description 58
- 108090000790 Enzymes Proteins 0.000 claims description 58
- 239000000427 antigen Substances 0.000 claims description 54
- 102000036639 antigens Human genes 0.000 claims description 54
- 108091007433 antigens Proteins 0.000 claims description 54
- 239000003418 antiprogestin Substances 0.000 claims description 52
- 230000003623 progesteronic effect Effects 0.000 claims description 52
- 241000191967 Staphylococcus aureus Species 0.000 claims description 48
- 239000000758 substrate Substances 0.000 claims description 48
- 229930040373 Paraformaldehyde Natural products 0.000 claims description 27
- 229920002866 paraformaldehyde Polymers 0.000 claims description 27
- 239000007795 chemical reaction product Substances 0.000 claims description 26
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims description 22
- 229940098773 bovine serum albumin Drugs 0.000 claims description 22
- 239000003795 chemical substances by application Substances 0.000 claims description 22
- 239000011148 porous material Substances 0.000 claims description 18
- 230000001580 bacterial effect Effects 0.000 claims description 17
- 230000015572 biosynthetic process Effects 0.000 claims description 15
- 238000004132 cross linking Methods 0.000 claims description 15
- 239000000047 product Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 13
- 230000009871 nonspecific binding Effects 0.000 claims description 13
- 239000000725 suspension Substances 0.000 claims description 11
- -1 polyethylene Polymers 0.000 claims description 10
- 239000004698 Polyethylene Substances 0.000 claims description 9
- 229920000573 polyethylene Polymers 0.000 claims description 9
- 238000005406 washing Methods 0.000 claims description 9
- 239000002250 absorbent Substances 0.000 claims description 8
- 230000002745 absorbent Effects 0.000 claims description 8
- 238000007254 oxidation reaction Methods 0.000 claims description 8
- 238000007865 diluting Methods 0.000 claims description 7
- 230000003647 oxidation Effects 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 238000004140 cleaning Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000013504 Triton X-100 Substances 0.000 claims description 4
- 229920004890 Triton X-100 Polymers 0.000 claims description 4
- 230000002860 competitive effect Effects 0.000 claims description 4
- 239000008363 phosphate buffer Substances 0.000 claims description 3
- 239000004094 surface-active agent Substances 0.000 claims description 3
- 230000002934 lysing effect Effects 0.000 claims description 2
- 238000000926 separation method Methods 0.000 claims 16
- 238000000151 deposition Methods 0.000 claims 6
- 230000000087 stabilizing effect Effects 0.000 claims 4
- 238000001035 drying Methods 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 238000012360 testing method Methods 0.000 abstract description 10
- 210000002966 serum Anatomy 0.000 abstract description 7
- 238000009826 distribution Methods 0.000 abstract description 4
- 238000010790 dilution Methods 0.000 abstract description 2
- 239000012895 dilution Substances 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 238000005259 measurement Methods 0.000 description 31
- 229940088598 enzyme Drugs 0.000 description 29
- 238000010521 absorption reaction Methods 0.000 description 9
- YRNWIFYIFSBPAU-UHFFFAOYSA-N 4-[4-(dimethylamino)phenyl]-n,n-dimethylaniline Chemical compound C1=CC(N(C)C)=CC=C1C1=CC=C(N(C)C)C=C1 YRNWIFYIFSBPAU-UHFFFAOYSA-N 0.000 description 8
- 230000012173 estrus Effects 0.000 description 7
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 6
- 239000006285 cell suspension Substances 0.000 description 6
- 230000035935 pregnancy Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 5
- 210000002421 cell wall Anatomy 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 4
- 230000009027 insemination Effects 0.000 description 4
- 230000035945 sensitivity Effects 0.000 description 4
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 3
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000003550 marker Substances 0.000 description 3
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 3
- 229920006395 saturated elastomer Polymers 0.000 description 3
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 239000003431 cross linking reagent Substances 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 2
- 230000027758 ovulation cycle Effects 0.000 description 2
- 150000002978 peroxides Chemical class 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- 150000003384 small molecules Chemical class 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- JTNGEYANGCBZLK-UHFFFAOYSA-N 1h-indol-3-yl dihydrogen phosphate Chemical compound C1=CC=C2C(OP(O)(=O)O)=CNC2=C1 JTNGEYANGCBZLK-UHFFFAOYSA-N 0.000 description 1
- ZTOJFFHGPLIVKC-UHFFFAOYSA-N 3-ethyl-2-[(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid Chemical compound S1C2=CC(S(O)(=O)=O)=CC=C2N(CC)C1=NN=C1SC2=CC(S(O)(=O)=O)=CC=C2N1CC ZTOJFFHGPLIVKC-UHFFFAOYSA-N 0.000 description 1
- QRXMUCSWCMTJGU-UHFFFAOYSA-N 5-bromo-4-chloro-3-indolyl phosphate Chemical compound C1=C(Br)C(Cl)=C2C(OP(O)(=O)O)=CNC2=C1 QRXMUCSWCMTJGU-UHFFFAOYSA-N 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 102000002464 Galactosidases Human genes 0.000 description 1
- 108010093031 Galactosidases Proteins 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- LDKDGDIWEUUXSH-UHFFFAOYSA-N Thymophthalein Chemical compound C1=C(O)C(C(C)C)=CC(C2(C3=CC=CC=C3C(=O)O2)C=2C(=CC(O)=C(C(C)C)C=2)C)=C1C LDKDGDIWEUUXSH-UHFFFAOYSA-N 0.000 description 1
- WMDDNKROYKCDJC-UHFFFAOYSA-N [4-[3-oxo-1-(4-phosphonooxyphenyl)-2-benzofuran-1-yl]phenyl] dihydrogen phosphate Chemical compound C1=CC(OP(O)(=O)O)=CC=C1C1(C=2C=CC(OP(O)(O)=O)=CC=2)C2=CC=CC=C2C(=O)O1 WMDDNKROYKCDJC-UHFFFAOYSA-N 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- OHDRQQURAXLVGJ-HLVWOLMTSA-N azane;(2e)-3-ethyl-2-[(e)-(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid Chemical compound [NH4+].[NH4+].S/1C2=CC(S([O-])(=O)=O)=CC=C2N(CC)C\1=N/N=C1/SC2=CC(S([O-])(=O)=O)=CC=C2N1CC OHDRQQURAXLVGJ-HLVWOLMTSA-N 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 210000004246 corpus luteum Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000029849 luteinization Effects 0.000 description 1
- 229940126619 mouse monoclonal antibody Drugs 0.000 description 1
- 229950006238 nadide Drugs 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 230000016087 ovulation Effects 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003270 steroid hormone Substances 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/549—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic with antigen or antibody entrapped within the carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/966—Chemistry: molecular biology and microbiology involving an enzyme system with high turnover rate or complement magnified assay, e.g. multi-enzyme systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/828—Protein A
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/815—Carrier is a synthetic polymer
- Y10S530/817—Entrapped within the carrier, e.g. gel, hollow fibre
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines Containing Plant Substances (AREA)
- Eye Examination Apparatus (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/778,554 US5063151A (en) | 1985-09-20 | 1985-09-20 | Immunoassay method and kit |
| PCT/US1986/001944 WO1987001811A1 (en) | 1985-09-20 | 1986-09-19 | Immunoassay method and kit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO872095D0 NO872095D0 (no) | 1987-05-19 |
| NO872095L true NO872095L (no) | 1987-05-19 |
Family
ID=25113750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO872095A NO872095L (no) | 1985-09-20 | 1987-05-19 | Immunologisk maalemetode og -sett. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5063151A (de) |
| EP (1) | EP0238631B1 (de) |
| JP (1) | JPS63501819A (de) |
| AT (1) | ATE87101T1 (de) |
| AU (1) | AU6470486A (de) |
| BR (1) | BR8606895A (de) |
| CA (1) | CA1276881C (de) |
| DE (1) | DE3688072T2 (de) |
| DK (1) | DK256387A (de) |
| ES (1) | ES2001129A6 (de) |
| FI (1) | FI872199A7 (de) |
| GR (1) | GR862397B (de) |
| NO (1) | NO872095L (de) |
| NZ (1) | NZ217314A (de) |
| PT (1) | PT83400B (de) |
| WO (1) | WO1987001811A1 (de) |
| ZA (1) | ZA866686B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE74193B1 (en) * | 1990-08-23 | 1997-07-16 | Enfer Tech Ltd | Hormone detection methods |
| ES2103834T3 (es) * | 1991-01-15 | 1997-10-01 | Bayer Ag | Complementacion de receptores de la superficie celular. |
| US5424193A (en) * | 1993-02-25 | 1995-06-13 | Quidel Corporation | Assays employing dyed microorganism labels |
| US7410807B2 (en) * | 2000-07-24 | 2008-08-12 | D Aurora Vito J | Pregnancy and sex identification test based on saliva or other bodily fluids |
| WO2002086120A1 (fr) * | 2001-04-20 | 2002-10-31 | Kansai Chemical Engineering Co., Ltd. | Proteine de liaison aux anticorps et d'expression de levure sur couche superficielle cellulaire et utilisation de ladite proteine |
| US7507585B2 (en) * | 2005-01-10 | 2009-03-24 | Whalen Erin J | Methods and systems for indentifying and monitoring S-nitrosothiols in biological samples |
| CA2787021A1 (en) * | 2009-02-05 | 2010-08-12 | Hydradx, Inc. | Diagnostic device and method |
| US9909167B2 (en) | 2014-06-23 | 2018-03-06 | The Board Of Trustees Of The Leland Stanford Junior University | On-slide staining by primer extension |
| CN104237511A (zh) * | 2014-10-16 | 2014-12-24 | 青岛中仁生物科技有限公司 | 一种检测瘦肉精的检测试剂 |
| CN117092344B (zh) * | 2023-07-19 | 2024-04-19 | 武汉睿奇生物工程有限公司 | 一种检测金黄色葡萄球菌蛋白a的试剂盒及其应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA659059A (en) * | 1963-03-05 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | Shaped structures for biological processes | |
| US3654090A (en) * | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
| US3666421A (en) * | 1971-04-05 | 1972-05-30 | Organon | Diagnostic test slide |
| CA983358A (en) * | 1971-09-08 | 1976-02-10 | Kenneth D. Bagshawe | Performance of chemical or biological reactions |
| DE2322533C2 (de) * | 1972-11-06 | 1986-08-28 | Pharmacia AB, Uppsala | Verfahren zum Binden von Immunoglobulin und Hilfsmittel zur Durchführung des Verfahrens |
| DE2736684A1 (de) * | 1977-08-16 | 1979-03-01 | Technical Research Affiliates | Nachweis von antigenen durch sensibilisierte mikrobische teilchen |
| NZ190452A (en) * | 1978-05-19 | 1981-04-24 | Becton Dickinson Co | Solid phase assay receptor contacted with analyte and then with labeled analyte |
| US4292296A (en) * | 1978-09-12 | 1981-09-29 | Baxter Travenol Laboratories, Inc. | Diagnostic method |
| US4235601A (en) * | 1979-01-12 | 1980-11-25 | Thyroid Diagnostics, Inc. | Test device and method for its use |
| US4230664A (en) * | 1979-01-23 | 1980-10-28 | Technion Research & Development Foundation Ltd. | Test pack kit for immunoassay |
| US4280816A (en) * | 1979-10-25 | 1981-07-28 | Nasik Elahi | Macroencapsulated immunosorbent assay technique and element therefor |
| US4399229A (en) * | 1980-04-14 | 1983-08-16 | Immutron, Inc. | Rapid radioimmunoassay product and method of making and using same |
| US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4517288A (en) * | 1981-01-23 | 1985-05-14 | American Hospital Supply Corp. | Solid phase system for ligand assay |
| US4394444A (en) * | 1982-06-21 | 1983-07-19 | Miles Laboratories, Inc. | Cofactor indicator compositions |
| SU1125549A1 (ru) * | 1982-11-16 | 1984-11-23 | Белорусский научно-исследовательский институт переливания крови | Способ получени иммуносорбента |
| AU2706384A (en) * | 1983-05-06 | 1984-11-08 | Monoclonal Antibodies Inc. | Colorimetric immunoassay on solid surface |
| JPS59205999A (ja) * | 1983-05-10 | 1984-11-21 | Wako Pure Chem Ind Ltd | 還元型補酵素の定量方法 |
| US4632901A (en) * | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
-
1985
- 1985-09-20 US US06/778,554 patent/US5063151A/en not_active Expired - Fee Related
-
1986
- 1986-08-21 NZ NZ217314A patent/NZ217314A/xx unknown
- 1986-08-22 CA CA000516613A patent/CA1276881C/en not_active Expired - Lifetime
- 1986-09-03 ZA ZA866686A patent/ZA866686B/xx unknown
- 1986-09-18 ES ES8601969A patent/ES2001129A6/es not_active Expired
- 1986-09-18 GR GR862397A patent/GR862397B/el unknown
- 1986-09-18 PT PT83400A patent/PT83400B/pt unknown
- 1986-09-19 AU AU64704/86A patent/AU6470486A/en not_active Abandoned
- 1986-09-19 WO PCT/US1986/001944 patent/WO1987001811A1/en not_active Ceased
- 1986-09-19 BR BR8606895A patent/BR8606895A/pt unknown
- 1986-09-19 AT AT86906108T patent/ATE87101T1/de not_active IP Right Cessation
- 1986-09-19 DE DE86906108T patent/DE3688072T2/de not_active Expired - Fee Related
- 1986-09-19 JP JP61505318A patent/JPS63501819A/ja active Pending
- 1986-09-19 EP EP86906108A patent/EP0238631B1/de not_active Expired - Lifetime
- 1986-09-19 FI FI872199A patent/FI872199A7/fi not_active IP Right Cessation
-
1987
- 1987-05-19 NO NO872095A patent/NO872095L/no unknown
- 1987-05-20 DK DK256387A patent/DK256387A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3688072T2 (de) | 1993-10-14 |
| ATE87101T1 (de) | 1993-04-15 |
| FI872199A0 (fi) | 1987-05-19 |
| JPS63501819A (ja) | 1988-07-21 |
| PT83400A (fr) | 1986-10-01 |
| EP0238631A4 (de) | 1989-06-21 |
| NZ217314A (en) | 1989-09-27 |
| EP0238631A1 (de) | 1987-09-30 |
| FI872199L (fi) | 1987-05-19 |
| NO872095D0 (no) | 1987-05-19 |
| US5063151A (en) | 1991-11-05 |
| WO1987001811A1 (en) | 1987-03-26 |
| DE3688072D1 (de) | 1993-04-22 |
| DK256387D0 (da) | 1987-05-20 |
| AU6470486A (en) | 1987-04-07 |
| CA1276881C (en) | 1990-11-27 |
| EP0238631B1 (de) | 1993-03-17 |
| BR8606895A (pt) | 1987-11-03 |
| ES2001129A6 (es) | 1988-04-16 |
| DK256387A (da) | 1987-05-20 |
| PT83400B (fr) | 1988-01-14 |
| ZA866686B (en) | 1987-08-26 |
| FI872199A7 (fi) | 1987-05-19 |
| GR862397B (en) | 1987-01-20 |
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