NO862559D0 - Fremgangsmaate for fremstilling av pyridoncarboxylsyrederivater. - Google Patents
Fremgangsmaate for fremstilling av pyridoncarboxylsyrederivater.Info
- Publication number
- NO862559D0 NO862559D0 NO862559A NO862559A NO862559D0 NO 862559 D0 NO862559 D0 NO 862559D0 NO 862559 A NO862559 A NO 862559A NO 862559 A NO862559 A NO 862559A NO 862559 D0 NO862559 D0 NO 862559D0
- Authority
- NO
- Norway
- Prior art keywords
- sup
- acid derivatives
- sub
- pyridon
- preparing
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- -1 PYRIDON CARBOXYL Chemical class 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004777 2-fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 abstract 1
- 125000006414 CCl Chemical group ClC* 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000555 isopropenyl group Chemical group [H]\C([H])=C(\*)C([H])([H])[H] 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Table Devices Or Equipment (AREA)
- Stringed Musical Instruments (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13983085 | 1985-06-26 | ||
| JP27999185 | 1985-12-12 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO862559D0 true NO862559D0 (no) | 1986-06-25 |
| NO862559L NO862559L (no) | 1986-12-29 |
| NO167090B NO167090B (no) | 1991-06-24 |
| NO167090C NO167090C (no) | 1991-10-02 |
Family
ID=26472527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO862559A NO167090C (no) | 1985-06-26 | 1986-06-25 | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoncarboxylsyrederivater. |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US5098912A (no) |
| EP (1) | EP0207420B1 (no) |
| JP (2) | JPH0745491B2 (no) |
| KR (1) | KR930005001B1 (no) |
| AT (1) | ATE75740T1 (no) |
| AU (1) | AU589978B2 (no) |
| CA (1) | CA1301760C (no) |
| DE (1) | DE3685157D1 (no) |
| DK (1) | DK170641B1 (no) |
| ES (1) | ES8707520A1 (no) |
| FI (1) | FI87071C (no) |
| GR (1) | GR861649B (no) |
| IE (1) | IE59188B1 (no) |
| IL (1) | IL79189A (no) |
| NO (1) | NO167090C (no) |
| PH (1) | PH24886A (no) |
| PT (1) | PT82839B (no) |
| YU (1) | YU46526B (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3508816A1 (de) * | 1985-01-10 | 1986-07-10 | Bayer Ag, 5090 Leverkusen | 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren |
| US4920120A (en) * | 1988-01-25 | 1990-04-24 | Warner-Lambert Company | Antibacterial agents |
| US5585491A (en) * | 1988-01-25 | 1996-12-17 | Otsuka Pharmaceutical Co., Ltd. | Antibacterial agents |
| CA1332605C (en) * | 1988-10-03 | 1994-10-18 | Yasuhiro Nishitani | Pyridonecarboxylic acids |
| US5258528A (en) * | 1990-11-30 | 1993-11-02 | Warner-Lambert Company | Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group |
| DK0559774T3 (da) * | 1990-11-30 | 2000-01-31 | Warner Lambert Co | Individuelle stereoisomerer af 7-/3-(1-aminoalkyl)-1-pyrrolidinal/-quinoloner og naphthyridoner som antibakterielle midler |
| US5157128A (en) * | 1990-11-30 | 1992-10-20 | Warner-Lambert Company | Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates |
| US5364861A (en) * | 1990-11-30 | 1994-11-15 | Warner-Lambert Company | Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents |
| EP0550016A1 (en) * | 1991-12-31 | 1993-07-07 | Korea Research Institute Of Chemical Technology | Novel quinolone carboxylic acid derivatives and processes for preparing same |
| ES2315432T3 (es) * | 1995-02-02 | 2009-04-01 | Daiichi Sankyo Company, Limited | Derivados de acido piridonacarboxilico y su uso como agentes antibacterianos. |
| US6121285A (en) * | 1995-11-22 | 2000-09-19 | Daiichi Pharmaceutical Co., Ltd. | Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives |
| CN1119343C (zh) * | 1995-11-22 | 2003-08-27 | 第一制药株式会社 | 取代的氨基环烷基吡咯烷衍生物 |
| DK0919553T3 (da) | 1996-07-12 | 2005-06-06 | Daiichi Seiyaku Co | cis-substituerede aminocyclopropanderivater |
| ID24434A (id) * | 1997-05-21 | 2000-07-20 | Daiichi Seiyaku Co | Derivat aminosikloalkilpirolidin tersubstitusi cis-tersubstitusi |
| ZA984527B (en) * | 1997-05-30 | 1998-12-03 | Daiichi Seiyaku Co | Substituted cyclobutylamine derivative |
| MY138335A (en) | 1997-09-15 | 2009-05-29 | Procter & Gamble | Antimicrobial quinolones, their compositions and uses |
| US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
| DK1082300T3 (da) * | 1998-05-29 | 2003-12-15 | Upjohn Co | 3-[1'-N-Methylamino)ethyl-N-benzyl]pyrrolidin-monomethansulfonat |
| ATE268329T1 (de) | 1999-03-10 | 2004-06-15 | Daiichi Seiyaku Co | Aminomethylpyrrolidin-derivate mit aromatischen substituenten |
| WO2001055698A1 (en) * | 2000-01-28 | 2001-08-02 | Pion, Inc. | MEASUREMENT OF SOLUBILITY-pH PROFILES |
| KR100777149B1 (ko) * | 2000-11-20 | 2007-11-19 | 다이이찌 세이야꾸 가부시기가이샤 | 데할로게노 화합물 |
| EP1666477B1 (en) | 2003-09-10 | 2013-07-03 | Kyorin Pharmaceutical Co., Ltd. | 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) q uinolonecarboxylic acid derivative |
| US7723524B2 (en) * | 2003-09-29 | 2010-05-25 | Daiichi Pharmaceutical Co., Ltd. | 8-cyanoquinolonecarboxylic acid derivative |
| JP4876165B2 (ja) * | 2006-03-28 | 2012-02-15 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体を調製するための水素化物還元法 |
| MX2008012328A (es) * | 2006-03-28 | 2008-10-09 | Procter & Gamble | Sales de malato, y polimorfos de acido (3s,5s)-7-[3-amino-5-metil- piperidinil]-1-ciclopropil-1,4-dihidro-8-metoxi-4-oxo-3-quinolinc arboxilico. |
| JP2009531418A (ja) * | 2006-03-28 | 2009-09-03 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体調製のためのカップリング方法 |
| WO2008143343A1 (ja) * | 2007-05-24 | 2008-11-27 | Kyorin Pharmaceutical Co., Ltd. | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
| DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| JPS60228479A (ja) * | 1984-04-26 | 1985-11-13 | Toyama Chem Co Ltd | １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩 |
| IE58742B1 (en) * | 1984-07-20 | 1993-11-05 | Warner Lambert Co | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds |
| DE3509546A1 (de) * | 1985-03-16 | 1986-09-25 | Bayer Ag, 5090 Leverkusen | 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| US4657913A (en) * | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
| EP0242789A3 (en) * | 1986-04-25 | 1990-09-05 | Dainippon Pharmaceutical Co., Ltd. | Novel quinoline derivates and processes for preparation thereof |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
| US4920120A (en) * | 1988-01-25 | 1990-04-24 | Warner-Lambert Company | Antibacterial agents |
-
1986
- 1986-06-23 AT AT86108547T patent/ATE75740T1/de not_active IP Right Cessation
- 1986-06-23 EP EP86108547A patent/EP0207420B1/en not_active Expired - Lifetime
- 1986-06-23 IL IL79189A patent/IL79189A/xx not_active IP Right Cessation
- 1986-06-23 DE DE8686108547T patent/DE3685157D1/de not_active Expired - Lifetime
- 1986-06-24 FI FI862688A patent/FI87071C/fi not_active IP Right Cessation
- 1986-06-25 PT PT82839A patent/PT82839B/pt unknown
- 1986-06-25 ES ES556754A patent/ES8707520A1/es not_active Expired
- 1986-06-25 NO NO862559A patent/NO167090C/no not_active IP Right Cessation
- 1986-06-25 IE IE169686A patent/IE59188B1/en not_active IP Right Cessation
- 1986-06-25 AU AU59245/86A patent/AU589978B2/en not_active Expired
- 1986-06-25 GR GR861649A patent/GR861649B/el unknown
- 1986-06-25 CA CA000512446A patent/CA1301760C/en not_active Expired - Lifetime
- 1986-06-26 YU YU112086A patent/YU46526B/sh unknown
- 1986-06-26 PH PH33956A patent/PH24886A/en unknown
- 1986-06-26 KR KR1019860005150A patent/KR930005001B1/ko not_active IP Right Cessation
- 1986-06-26 DK DK304686A patent/DK170641B1/da not_active IP Right Cessation
- 1986-06-26 JP JP61150581A patent/JPH0745491B2/ja not_active Expired - Lifetime
-
1989
- 1989-12-12 US US07/449,160 patent/US5098912A/en not_active Expired - Lifetime
-
1991
- 1991-12-24 US US07/812,830 patent/US5416222A/en not_active Expired - Lifetime
-
1993
- 1993-06-21 JP JP5148887A patent/JP2686705B2/ja not_active Expired - Lifetime
-
1994
- 1994-03-04 US US08/205,638 patent/US5380874A/en not_active Expired - Lifetime
-
1995
- 1995-03-20 US US08/406,594 patent/US5476950A/en not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |