NO813248L - Fremstilling av human-fibroblast-interferon. - Google Patents
Fremstilling av human-fibroblast-interferon.Info
- Publication number
- NO813248L NO813248L NO813248A NO813248A NO813248L NO 813248 L NO813248 L NO 813248L NO 813248 A NO813248 A NO 813248A NO 813248 A NO813248 A NO 813248A NO 813248 L NO813248 L NO 813248L
- Authority
- NO
- Norway
- Prior art keywords
- amino acid
- sequence
- polypeptide
- interferon
- dna
- Prior art date
Links
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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- 229940104230 thymidine Drugs 0.000 description 1
- LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO871590A NO871590D0 (no) | 1980-09-25 | 1987-04-14 | Mikrobiell ekspresjonsbaerer. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19079980A | 1980-09-25 | 1980-09-25 | |
| US29189281A | 1981-08-11 | 1981-08-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO813248L true NO813248L (no) | 1982-03-26 |
Family
ID=26886463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO813248A NO813248L (no) | 1980-09-25 | 1981-09-24 | Fremstilling av human-fibroblast-interferon. |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5460811A (ro) |
| EP (1) | EP0048970A3 (ro) |
| AT (1) | AT380694B (ro) |
| AU (1) | AU582110B2 (ro) |
| BR (1) | BR8106137A (ro) |
| CA (1) | CA1341569C (ro) |
| CH (2) | CH656388A5 (ro) |
| DD (3) | DD202085A5 (ro) |
| DE (1) | DE3138096A1 (ro) |
| DK (1) | DK423381A (ro) |
| ES (3) | ES8307297A1 (ro) |
| FI (1) | FI812993L (ro) |
| FR (1) | FR2490675B1 (ro) |
| GB (1) | GB2098996B (ro) |
| GR (1) | GR81946B (ro) |
| HK (1) | HK43686A (ro) |
| IE (1) | IE51679B1 (ro) |
| IL (1) | IL63916A0 (ro) |
| IT (1) | IT1139487B (ro) |
| KE (1) | KE3630A (ro) |
| LU (1) | LU83648A1 (ro) |
| MC (1) | MC1423A1 (ro) |
| MT (1) | MTP900B (ro) |
| MY (1) | MY8600634A (ro) |
| NL (1) | NL8104400A (ro) |
| NO (1) | NO813248L (ro) |
| NZ (1) | NZ198445A (ro) |
| OA (1) | OA06908A (ro) |
| PL (1) | PL233194A1 (ro) |
| PT (1) | PT73728B (ro) |
| SE (1) | SE8105657L (ro) |
| YU (1) | YU44835B (ro) |
| ZW (1) | ZW23981A1 (ro) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK33181A (da) * | 1980-02-06 | 1981-08-07 | Searle & Co | Fremgangsmaade til fremstilling af et interferonlignende protein |
| ZA811368B (en) * | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| PT72786B (en) | 1980-04-03 | 1983-01-10 | Biogen Nv | Process for producing dna sequences recombinant dna molecules and human fibroplast interferon-like polypeptides |
| DE3176011D1 (en) * | 1980-06-12 | 1987-04-23 | Japan Found Cancer | Plasmid |
| DK489481A (da) * | 1980-11-10 | 1982-05-11 | Searle & Co | Plasmidvektor og frmgangsmaade til fremstilling deraf |
| NZ199722A (en) * | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| JPS58110600A (ja) * | 1981-12-25 | 1983-07-01 | Kyowa Hakko Kogyo Co Ltd | ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド |
| US4775622A (en) * | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| IE54592B1 (en) * | 1982-03-08 | 1989-12-06 | Genentech Inc | Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby |
| US6432677B1 (en) | 1982-03-08 | 2002-08-13 | Genentech, Inc. | Non-human animal interferons |
| US5827694A (en) * | 1982-03-08 | 1998-10-27 | Genentech, Inc. | DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides |
| AU575301B2 (en) * | 1982-10-08 | 1988-07-28 | Juridical Foundation, Japanese Foundation For Cancer Research | Novel vector |
| US5831023A (en) * | 1982-11-01 | 1998-11-03 | Genentech, Inc. | Recombinant animal interferon polypeptides |
| US4512922A (en) * | 1982-12-22 | 1985-04-23 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4620948A (en) * | 1982-12-22 | 1986-11-04 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4511502A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4599197A (en) * | 1982-12-22 | 1986-07-08 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4518526A (en) * | 1982-12-22 | 1985-05-21 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| GR79124B (ro) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
| US5683688A (en) | 1984-05-31 | 1997-11-04 | Genentech, Inc. | Unglycosylated recombinant human lymphotoxin polypeptides and compositions |
| GB8414354D0 (en) * | 1984-06-05 | 1984-07-11 | Biogen Nv | Purifying protein |
| US5231176A (en) * | 1984-08-27 | 1993-07-27 | Genentech, Inc. | Distinct family DNA encoding of human leukocyte interferons |
| EP0174143B1 (en) * | 1984-08-27 | 1989-11-08 | Genentech, Inc. | Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and dna and transfected hosts therefor |
| US4680262A (en) * | 1984-10-05 | 1987-07-14 | Genentech, Inc. | Periplasmic protein recovery |
| US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| EP0237019A3 (en) * | 1986-03-14 | 1988-03-09 | Toray Industries, Inc. | Interferon conjugate and production thereof using recombinant gene |
| GB9022543D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
| FR2686899B1 (fr) * | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| US20050002902A1 (en) * | 1995-12-28 | 2005-01-06 | Liming Yu | Hybrid with interferon-alpha and an immunoglobulin Fc for treatment of tumors and viral infections |
| US20030026779A1 (en) * | 1999-10-15 | 2003-02-06 | Liming Yu | Treatment of tumors and viral infections with a hybrid conjugate of interferon and an immunoglobulin Fc |
| US5723125A (en) * | 1995-12-28 | 1998-03-03 | Tanox Biosystems, Inc. | Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide |
| US6713609B1 (en) * | 1996-07-16 | 2004-03-30 | Genentech, Inc. | Monoclonal antibodies to type I interferon receptor |
| JP3576819B2 (ja) | 1997-07-30 | 2004-10-13 | キヤノン株式会社 | 情報処理装置及び印刷制御方法並びに記憶媒体 |
| US20030018174A1 (en) * | 1997-10-06 | 2003-01-23 | Genentech, Inc. | Monoclonal antibodies to IFNAR2 |
| EP1165835A2 (en) | 1999-03-24 | 2002-01-02 | Serono Genetics Institute S.A. | GENOMIC SEQUENCE OF THE $i(PURH) GENE AND $i(PURH)-RELATED BIALLELIC MARKERS |
| CA2405557C (en) | 2000-04-12 | 2013-09-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| CN101612402A (zh) * | 2001-01-09 | 2009-12-30 | 贝勒研究院 | 干扰素拮抗剂和Flt3L拮抗剂的用途 |
| KR101271635B1 (ko) * | 2001-12-21 | 2013-06-12 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 알부민 융합 단백질 |
| ES2545090T3 (es) | 2001-12-21 | 2015-09-08 | Human Genome Sciences, Inc. | Proteínas de fusión de albúmina y GCSF |
| WO2005003296A2 (en) | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| CA2511814C (en) | 2002-12-26 | 2015-02-17 | Mountain View Pharmaceuticals, Inc. | Polymer conjugates of interferon-beta with enhanced biological potency |
| RS20050501A (en) * | 2002-12-26 | 2007-08-03 | Mountain View Pharmaceuticals Inc., | Polymer conjugates of cytokines,chemokines,growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity |
| WO2005074546A2 (en) | 2004-02-02 | 2005-08-18 | Ambrx, Inc. | Modified human growth hormone polypeptides and their uses |
| US20070081995A1 (en) * | 2005-06-22 | 2007-04-12 | Genentech, Inc. | Methods and compositions for targeting IFNAR2 |
| EP3103880A1 (en) | 2008-02-08 | 2016-12-14 | Ambrx, Inc. | Modified leptin polypeptides and their uses |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT373279B (de) * | 1977-11-08 | 1984-01-10 | Genentech Inc | Verfahren zur herstellung eines rekombinationsclonbildungstraegers |
| US4411994A (en) * | 1978-06-08 | 1983-10-25 | The President And Fellows Of Harvard College | Protein synthesis |
| IN150740B (ro) * | 1978-11-24 | 1982-12-04 | Hoffmann La Roche | |
| US4332892A (en) * | 1979-01-15 | 1982-06-01 | President And Fellows Of Harvard College | Protein synthesis |
| US4262090A (en) * | 1979-06-04 | 1981-04-14 | Cetus Corporation | Interferon production |
| US4342832A (en) * | 1979-07-05 | 1982-08-03 | Genentech, Inc. | Method of constructing a replicable cloning vehicle having quasi-synthetic genes |
| US4289689A (en) * | 1980-03-14 | 1981-09-15 | Hoffmann-La Roche Inc. | Preparation of homogeneous human fibroblast interferon |
| CH648331A5 (de) * | 1979-07-31 | 1985-03-15 | Hoffmann La Roche | Homogenes fibroblasten-interferon und dessen herstellung. |
| AU538665B2 (en) * | 1979-10-30 | 1984-08-23 | Juridical Foundation, Japanese Foundation For Cancer Research | Human interferon dna |
| IL58765A (en) * | 1979-11-21 | 1986-09-30 | Yeda Res & Dev | Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta |
| US4418149A (en) * | 1980-01-10 | 1983-11-29 | President And Fellows Of Harvard College | Fused hybrid gene |
| GB2068970B (en) * | 1980-02-06 | 1983-06-22 | Searle & Co | Recombinant dna technique for the preparation of a protein resembling human interferon |
| DK33181A (da) * | 1980-02-06 | 1981-08-07 | Searle & Co | Fremgangsmaade til fremstilling af et interferonlignende protein |
| DE3005843A1 (de) * | 1980-02-16 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus |
| PT72786B (en) * | 1980-04-03 | 1983-01-10 | Biogen Nv | Process for producing dna sequences recombinant dna molecules and human fibroplast interferon-like polypeptides |
| DE3176011D1 (en) * | 1980-06-12 | 1987-04-23 | Japan Found Cancer | Plasmid |
| US4874702A (en) * | 1980-09-08 | 1989-10-17 | Biogen, Inc. | Vectors and methods for making such vectors and for expressive cloned genes |
-
1981
- 1981-09-23 GR GR66114A patent/GR81946B/el unknown
- 1981-09-23 IT IT24109/81A patent/IT1139487B/it active
- 1981-09-23 FR FR8117933A patent/FR2490675B1/fr not_active Expired
- 1981-09-23 IL IL63916A patent/IL63916A0/xx unknown
- 1981-09-23 NZ NZ198445A patent/NZ198445A/en unknown
- 1981-09-24 CH CH238/85A patent/CH656388A5/de not_active IP Right Cessation
- 1981-09-24 AT AT0410381A patent/AT380694B/de not_active IP Right Cessation
- 1981-09-24 ES ES505742A patent/ES8307297A1/es not_active Expired
- 1981-09-24 AU AU75649/81A patent/AU582110B2/en not_active Ceased
- 1981-09-24 CA CA000386573A patent/CA1341569C/en not_active Expired - Fee Related
- 1981-09-24 NL NL8104400A patent/NL8104400A/nl not_active Application Discontinuation
- 1981-09-24 NO NO813248A patent/NO813248L/no unknown
- 1981-09-24 GB GB8128952A patent/GB2098996B/en not_active Expired
- 1981-09-24 DE DE19813138096 patent/DE3138096A1/de not_active Withdrawn
- 1981-09-24 YU YU2297/81A patent/YU44835B/xx unknown
- 1981-09-24 BR BR8106137A patent/BR8106137A/pt unknown
- 1981-09-24 DK DK423381A patent/DK423381A/da not_active Application Discontinuation
- 1981-09-24 SE SE8105657A patent/SE8105657L/ not_active Application Discontinuation
- 1981-09-24 LU LU83648A patent/LU83648A1/de unknown
- 1981-09-24 IE IE2224/81A patent/IE51679B1/en not_active IP Right Cessation
- 1981-09-24 PT PT73728A patent/PT73728B/pt not_active IP Right Cessation
- 1981-09-24 MC MC811542A patent/MC1423A1/xx unknown
- 1981-09-24 MT MT900A patent/MTP900B/xx unknown
- 1981-09-24 CH CH6169/81A patent/CH651309A5/de not_active IP Right Cessation
- 1981-09-24 EP EP81107621A patent/EP0048970A3/en not_active Withdrawn
- 1981-09-24 ZW ZW239/81A patent/ZW23981A1/xx unknown
- 1981-09-25 PL PL23319481A patent/PL233194A1/xx unknown
- 1981-09-25 FI FI812993A patent/FI812993L/fi not_active Application Discontinuation
- 1981-09-25 DD DD81233598A patent/DD202085A5/de unknown
- 1981-09-25 DD DD81249414A patent/DD209652A5/de unknown
- 1981-09-25 OA OA57503A patent/OA06908A/xx unknown
- 1981-09-25 DD DD81249415A patent/DD209477A5/de unknown
-
1982
- 1982-08-16 ES ES515033A patent/ES515033A0/es active Granted
- 1982-08-16 ES ES515032A patent/ES8306324A1/es not_active Expired
-
1986
- 1986-04-14 KE KE3630A patent/KE3630A/xx unknown
- 1986-06-09 HK HK436/86A patent/HK43686A/xx unknown
- 1986-12-30 MY MY634/86A patent/MY8600634A/xx unknown
-
1989
- 1989-06-12 US US07/365,284 patent/US5460811A/en not_active Expired - Lifetime
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