NO801775L - Fremgangsmaate ved fremstilling av hypocholesteremiske forbindelser - Google Patents
Fremgangsmaate ved fremstilling av hypocholesteremiske forbindelserInfo
- Publication number
- NO801775L NO801775L NO801775A NO801775A NO801775L NO 801775 L NO801775 L NO 801775L NO 801775 A NO801775 A NO 801775A NO 801775 A NO801775 A NO 801775A NO 801775 L NO801775 L NO 801775L
- Authority
- NO
- Norway
- Prior art keywords
- hypocholesteremic
- compounds
- procedure
- preparation
- hypocholesteremic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/66—Aspergillus
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/048,946 US4231938A (en) | 1979-06-15 | 1979-06-15 | Hypocholesteremic fermentation products and process of preparation |
| US7780779A | 1979-09-21 | 1979-09-21 | |
| US11445980A | 1980-01-23 | 1980-01-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO801775L true NO801775L (no) | 1980-12-16 |
| NO155699B NO155699B (no) | 1987-02-02 |
| NO155699C NO155699C (no) | 1987-05-13 |
Family
ID=27367450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO801775A NO155699C (no) | 1979-06-15 | 1980-06-13 | Fremgangsmaate ved fremstilling av hypocholesteremiske forbindelser. |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0022478B1 (no) |
| AR (1) | AR224008A1 (no) |
| AT (1) | ATE2620T1 (no) |
| AU (1) | AU535944B2 (no) |
| CA (1) | CA1161380A (no) |
| DD (1) | DD157344A5 (no) |
| DE (1) | DE3062122D1 (no) |
| DK (1) | DK149003C (no) |
| EG (1) | EG16957A (no) |
| ES (1) | ES492384A0 (no) |
| FI (1) | FI67231C (no) |
| GR (1) | GR69216B (no) |
| IE (1) | IE49685B1 (no) |
| IL (1) | IL60219A (no) |
| NO (1) | NO155699C (no) |
| NZ (1) | NZ193922A (no) |
| PL (1) | PL125843B1 (no) |
| PT (1) | PT71371B (no) |
| RO (1) | RO79487A (no) |
| ZW (1) | ZW13480A1 (no) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5925599B2 (ja) * | 1979-02-20 | 1984-06-19 | 三共株式会社 | 新生理活性物質モナコリンｋおよびその製造法 |
| JPS55150898A (en) * | 1979-05-11 | 1980-11-25 | Sankyo Co Ltd | Preparation of a new physiologically active substance mb-530b |
| PT72394B (en) * | 1980-02-04 | 1982-09-06 | Merck & Co Inc | Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics |
| US4282155A (en) * | 1980-02-04 | 1981-08-04 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| AU548996B2 (en) * | 1980-02-04 | 1986-01-09 | Merck & Co., Inc. | Tetrahydro-2h-pyran-2-one derivatives |
| JPH0692381B2 (ja) * | 1980-03-31 | 1994-11-16 | 三共株式会社 | Ｍｂ−５３０ａ誘導体 |
| DK149080C (da) * | 1980-06-06 | 1986-07-28 | Sankyo Co | Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre |
| JPS5835144A (ja) * | 1981-08-27 | 1983-03-01 | Sankyo Co Ltd | Ｍｂ−５３０ｂ誘導体およびその製造法 |
| DE8533814U1 (de) * | 1985-11-30 | 1986-01-16 | Beiersdorf Ag, 2000 Hamburg | Vorrichtung zum Spülen des Darmes |
| US4681893A (en) * | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
| US4678806A (en) * | 1986-09-02 | 1987-07-07 | Merck & Co., Inc. | Prodrugs of antihypercholesterolemic compounds |
| DE3739882A1 (de) * | 1987-11-25 | 1989-06-08 | Bayer Ag | Substituierte hydroxylamine |
| NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
| AU618158B2 (en) * | 1989-01-07 | 1991-12-12 | Bayer Aktiengesellschaft | New substituted pyrido(2,3-d)pyrimidines |
| DE3911064A1 (de) * | 1989-04-06 | 1990-10-11 | Bayer Ag | Substituierte 1,8-naphthyridine |
| FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| CA2062023A1 (en) | 1992-02-10 | 1993-08-11 | Jagroop S. Dahiya | Novel fungal strains and use thereof in antibiotic production |
| NZ245713A (en) * | 1992-02-10 | 1994-12-22 | Novopharm Ltd | Production of the antibiotic lovastatin from genetically engineered aspergillus strains |
| JPH07504568A (ja) * | 1992-03-04 | 1995-05-25 | 藤沢薬品工業株式会社 | ＨＭＧ−ＣｏＡレダクターゼ阻害物質としてのテトラリン誘導体 |
| HU210867B (en) * | 1992-11-04 | 1995-10-30 | Biogal Gyogyszergyar | Method for extraction and purification of mevinolin from culture medium |
| DE4244029A1 (de) * | 1992-12-24 | 1994-06-30 | Bayer Ag | Neue substituierte Pyridine |
| SI9300303A (en) * | 1993-06-08 | 1994-12-31 | Krka Tovarna Zdravil | Process for isolation of hypolipemic effective substance |
| US5409820A (en) * | 1993-08-06 | 1995-04-25 | Apotex, Inc. | Process for the production of lovastatin using Coniothyrium fuckelii |
| RU2158607C2 (ru) * | 1995-07-03 | 2000-11-10 | Санкио Компани Лимитед | Лечение артериосклероза и ксантомы |
| CA2199104A1 (en) | 1996-03-05 | 1997-09-05 | Tsuneaki Hida | Xanthene derivatives, their production and use |
| KR100576576B1 (ko) * | 1997-02-20 | 2006-05-04 | 디에스엠 아이피 어셋츠 비.브이. | 화학적 합성 배지를 이용하는 가치있는 화합물들의 산업적 규모의 발효적 생산 |
| US6083497A (en) | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| SI9800057A (sl) | 1998-02-26 | 1999-08-31 | Krka, Tovarna Zdravil, D.D. | Postopek za pripravo simvastatina in njegovih derivatov |
| EP2359826B1 (en) | 2006-07-05 | 2013-10-30 | Takeda GmbH | Combination of HMG-COA reductase inhibitor rosuvastatin with a phosphodiesterase 4 inhibitor, such as roflumilast, roflumilast-N-oxide for the treatment of inflammatory pulmonary diseases |
| EP2373609B1 (en) | 2008-12-19 | 2013-10-16 | KRKA, D.D., Novo Mesto | Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates |
| EP2327682A1 (en) | 2009-10-29 | 2011-06-01 | KRKA, D.D., Novo Mesto | Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4049495A (en) * | 1974-06-07 | 1977-09-20 | Sankyo Company Limited | Physiologically active substances and fermentative process for producing the same |
| JPS5559180A (en) * | 1978-10-30 | 1980-05-02 | Sankyo Co Ltd | 4-hydroxy-2-pyrone ring compound, its preparation, and remedy for hyperlipemia comprising it as active constituent |
-
1980
- 1980-06-03 GR GR62115A patent/GR69216B/el unknown
- 1980-06-03 IL IL60219A patent/IL60219A/xx unknown
- 1980-06-03 AU AU59017/80A patent/AU535944B2/en not_active Expired
- 1980-06-04 AR AR281295A patent/AR224008A1/es active
- 1980-06-04 NZ NZ193922A patent/NZ193922A/xx unknown
- 1980-06-06 ZW ZW134/80A patent/ZW13480A1/xx unknown
- 1980-06-09 RO RO80101368A patent/RO79487A/ro unknown
- 1980-06-10 FI FI801857A patent/FI67231C/fi not_active IP Right Cessation
- 1980-06-11 PT PT71371A patent/PT71371B/pt unknown
- 1980-06-11 CA CA000353777A patent/CA1161380A/en not_active Expired
- 1980-06-12 ES ES492384A patent/ES492384A0/es active Granted
- 1980-06-12 DE DE8080103286T patent/DE3062122D1/de not_active Expired
- 1980-06-12 AT AT80103286T patent/ATE2620T1/de active
- 1980-06-12 PL PL1980224920A patent/PL125843B1/pl unknown
- 1980-06-12 EP EP80103286A patent/EP0022478B1/en not_active Expired
- 1980-06-13 DD DD80221832A patent/DD157344A5/de unknown
- 1980-06-13 IE IE1232/80A patent/IE49685B1/en not_active IP Right Cessation
- 1980-06-13 NO NO801775A patent/NO155699C/no unknown
- 1980-06-13 DK DK254180A patent/DK149003C/da not_active IP Right Cessation
- 1980-06-14 EG EG355/80A patent/EG16957A/xx active
Also Published As
| Publication number | Publication date |
|---|---|
| DK149003B (da) | 1985-12-16 |
| PT71371A (en) | 1980-07-01 |
| ATE2620T1 (de) | 1983-03-15 |
| IE49685B1 (en) | 1985-11-27 |
| RO79487A (ro) | 1982-07-06 |
| EP0022478A1 (en) | 1981-01-21 |
| DK149003C (da) | 1986-08-18 |
| ES8105389A1 (es) | 1981-06-01 |
| DE3062122D1 (en) | 1983-03-31 |
| IL60219A0 (en) | 1980-09-16 |
| NO155699C (no) | 1987-05-13 |
| PL125843B1 (en) | 1983-06-30 |
| ZW13480A1 (en) | 1982-02-03 |
| NO155699B (no) | 1987-02-02 |
| AU535944B2 (en) | 1984-04-12 |
| EG16957A (en) | 1990-06-30 |
| FI67231C (fi) | 1985-02-11 |
| NZ193922A (en) | 1982-05-25 |
| FI67231B (fi) | 1984-10-31 |
| PL224920A1 (no) | 1981-03-27 |
| DK254180A (da) | 1980-12-16 |
| GR69216B (no) | 1982-05-07 |
| IE801232L (en) | 1980-12-15 |
| IL60219A (en) | 1985-05-31 |
| AU5901780A (en) | 1980-12-18 |
| AR224008A1 (es) | 1981-10-15 |
| FI801857A (fi) | 1980-12-16 |
| PT71371B (en) | 1981-10-21 |
| DD157344A5 (de) | 1982-11-03 |
| ES492384A0 (es) | 1981-06-01 |
| EP0022478B1 (en) | 1983-02-23 |
| CA1161380A (en) | 1984-01-31 |
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