NO752939L - - Google Patents

Info

Publication number
NO752939L
NO752939L NO752939A NO752939A NO752939L NO 752939 L NO752939 L NO 752939L NO 752939 A NO752939 A NO 752939A NO 752939 A NO752939 A NO 752939A NO 752939 L NO752939 L NO 752939L
Authority
NO
Norway
Prior art keywords
hpi
oxo
methyl
hydrogen
acid
Prior art date
Application number
NO752939A
Other languages
English (en)
Norwegian (no)
Inventor
J Seubert
R Pohlke
H Thomas
P Andrews
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO752939L publication Critical patent/NO752939L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO752939A 1974-08-28 1975-08-27 NO752939L (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2441261A DE2441261A1 (de) 1974-08-28 1974-08-28 Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
NO752939L true NO752939L (fr) 1976-03-02

Family

ID=5924323

Family Applications (1)

Application Number Title Priority Date Filing Date
NO752939A NO752939L (fr) 1974-08-28 1975-08-27

Country Status (22)

Country Link
US (1) US4051243A (fr)
JP (1) JPS5168595A (fr)
AT (1) AT350055B (fr)
BE (1) BE832735A (fr)
CH (3) CH617934A5 (fr)
DD (1) DD121789A5 (fr)
DE (1) DE2441261A1 (fr)
DK (1) DK386175A (fr)
EG (1) EG12384A (fr)
ES (1) ES440509A1 (fr)
FI (1) FI752411A (fr)
FR (1) FR2282891A1 (fr)
GB (1) GB1479235A (fr)
IE (1) IE42218B1 (fr)
IL (1) IL47975A (fr)
LU (1) LU73263A1 (fr)
NL (1) NL7510173A (fr)
NO (1) NO752939L (fr)
OA (1) OA05094A (fr)
PH (1) PH12677A (fr)
SE (1) SE7509473L (fr)
ZA (1) ZA755480B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4113867A (en) * 1973-12-17 1978-09-12 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4120961A (en) * 1974-08-28 1978-10-17 E. Merck Ring substituted pyrazino-isoquinoline derivatives and their preparation
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
US4517187A (en) * 1982-10-18 1985-05-14 Pennwalt Corporation 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
US4772705A (en) * 1985-07-25 1988-09-20 Pennwalt Corporation Processes for the preparation of trans 1,3,4,6,7,11b-hexahydro-7-aryl-2H-pyrazinol[2,1-a]isoquinolines
US20040131560A1 (en) * 2002-10-04 2004-07-08 The Procter & Gamble Company Oral compositions and use thereof
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
EP2662353A3 (fr) * 2007-06-12 2014-04-02 Achaogen, Inc. Agents antibactériens
CN101691367B (zh) * 2009-08-31 2013-07-24 中国人民解放军第二军医大学 具有抗真菌活性的哌嗪并[2,1-a]异喹啉类化合物或其盐类
US20220227765A1 (en) * 2019-08-28 2022-07-21 Ferro Therapeutics, Inc. Pyrido-indole analogues as gpx4 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
FR2282891B1 (fr) 1980-03-28
DD121789A5 (fr) 1976-08-20
LU73263A1 (fr) 1977-04-15
ATA663375A (de) 1978-10-15
IL47975A (en) 1980-05-30
FR2282891A1 (fr) 1976-03-26
ZA755480B (en) 1976-07-28
ES440509A1 (es) 1977-06-01
DE2441261A1 (de) 1976-03-18
IE42218L (en) 1976-02-28
IL47975A0 (en) 1975-11-25
OA05094A (fr) 1981-01-31
CH623584A5 (fr) 1981-06-15
CH617934A5 (fr) 1980-06-30
DK386175A (da) 1976-02-29
BE832735A (nl) 1976-02-25
AT350055B (de) 1979-05-10
GB1479235A (en) 1977-07-06
IE42218B1 (en) 1980-07-02
FI752411A (fr) 1976-02-29
AU8410675A (en) 1977-02-24
US4051243A (en) 1977-09-27
CH624113A5 (fr) 1981-07-15
JPS5168595A (en) 1976-06-14
SE7509473L (sv) 1976-03-01
NL7510173A (nl) 1976-03-02
PH12677A (en) 1979-07-11
EG12384A (en) 1980-03-31

Similar Documents

Publication Publication Date Title
US4001411A (en) 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
NO752939L (fr)
US5281620A (en) Compounds having antitumor and antibacterial properties
US4217349A (en) Benzisoxazole derivatives
IL37749A (en) Pyridoquinoline derivatives,their preparation and pharmaceutical compositions containing them
PL139439B1 (en) Method of obtaining imidazoline derivatives
SU1217254A3 (ru) Способ получени производных 9-амино-1-оксиоктагидробензо( @ )хинолина или их фармацевтически приемлемых солей
WO1997010824A1 (fr) Utilisation d'antagonistes du recepteur 5ht1b pour le traitement de maladies vasculaires
NO142865B (no) Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karbazoler
US4122176A (en) 3-(Piperazinoalkyl)-benz-2,1-isoxazoles
NO139685B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive isoindolin-derivater
US4162319A (en) Ring substituted pyrazino-isoquinoline derivatives and their preparation
CH617694A5 (fr)
US4273773A (en) Antihypertensive tricyclic isoindole derivatives
Mooradian et al. 3-Aminotetrahydrocarbazoles as a new series of central nervous system agents
CS249126B2 (en) Method of substituted hexahydropyrrolo-(1,2-a)quinolines,hexahydro-1h-pyrido(1,2-a)quinolines and octahydrophenanthrenes production
US4120961A (en) Ring substituted pyrazino-isoquinoline derivatives and their preparation
US4141978A (en) 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
SU1017170A3 (ru) Способ получени производных 3-амино-1-бензоксепина или их стереоизомеров, или их солей
US3518278A (en) Substituted-1,2,3,4-tetrahydrobenzothieno 2,3-pyridine
US4196291A (en) 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US3248292A (en) Pharmaceutically active dimethoxyquinazolines
US4420476A (en) Benzofuro[3,2-c]pyrazol-3-amine derivatives
Cannon et al. 5, 7-Dihydroxy-2-aminotetralin derivatives: synthesis and assessment of dopaminergic and adrenergic actions
KR800000031B1 (ko) 환치환 4-옥소-및 4-티옥소-헥사하이드로-4H-피라지노-[2.1-a] 이소퀴놀린 유도체의 제조법