SE7509473L - Ringsubstituerade pyrazino-isokinolin-derivat och forfarande for framstellning derav - Google Patents

Ringsubstituerade pyrazino-isokinolin-derivat och forfarande for framstellning derav

Info

Publication number
SE7509473L
SE7509473L SE7509473A SE7509473A SE7509473L SE 7509473 L SE7509473 L SE 7509473L SE 7509473 A SE7509473 A SE 7509473A SE 7509473 A SE7509473 A SE 7509473A SE 7509473 L SE7509473 L SE 7509473L
Authority
SE
Sweden
Prior art keywords
isokinoline
procedures
derivatives
ring
substituted pyrazino
Prior art date
Application number
SE7509473A
Other languages
English (en)
Swedish (sv)
Inventor
J Seubert
R Pohlke
H Thomas
P Andrews
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SE7509473L publication Critical patent/SE7509473L/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
SE7509473A 1974-08-28 1975-08-26 Ringsubstituerade pyrazino-isokinolin-derivat och forfarande for framstellning derav SE7509473L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2441261A DE2441261A1 (de) 1974-08-28 1974-08-28 Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
SE7509473L true SE7509473L (sv) 1976-03-01

Family

ID=5924323

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7509473A SE7509473L (sv) 1974-08-28 1975-08-26 Ringsubstituerade pyrazino-isokinolin-derivat och forfarande for framstellning derav

Country Status (22)

Country Link
US (1) US4051243A (fr)
JP (1) JPS5168595A (fr)
AT (1) AT350055B (fr)
BE (1) BE832735A (fr)
CH (3) CH617934A5 (fr)
DD (1) DD121789A5 (fr)
DE (1) DE2441261A1 (fr)
DK (1) DK386175A (fr)
EG (1) EG12384A (fr)
ES (1) ES440509A1 (fr)
FI (1) FI752411A (fr)
FR (1) FR2282891A1 (fr)
GB (1) GB1479235A (fr)
IE (1) IE42218B1 (fr)
IL (1) IL47975A (fr)
LU (1) LU73263A1 (fr)
NL (1) NL7510173A (fr)
NO (1) NO752939L (fr)
OA (1) OA05094A (fr)
PH (1) PH12677A (fr)
SE (1) SE7509473L (fr)
ZA (1) ZA755480B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4113867A (en) * 1973-12-17 1978-09-12 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4120961A (en) * 1974-08-28 1978-10-17 E. Merck Ring substituted pyrazino-isoquinoline derivatives and their preparation
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
US4517187A (en) * 1982-10-18 1985-05-14 Pennwalt Corporation 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
US4772705A (en) * 1985-07-25 1988-09-20 Pennwalt Corporation Processes for the preparation of trans 1,3,4,6,7,11b-hexahydro-7-aryl-2H-pyrazinol[2,1-a]isoquinolines
US20040131560A1 (en) * 2002-10-04 2004-07-08 The Procter & Gamble Company Oral compositions and use thereof
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
EP2662353A3 (fr) * 2007-06-12 2014-04-02 Achaogen, Inc. Agents antibactériens
CN101691367B (zh) * 2009-08-31 2013-07-24 中国人民解放军第二军医大学 具有抗真菌活性的哌嗪并[2,1-a]异喹啉类化合物或其盐类
US20220227765A1 (en) * 2019-08-28 2022-07-21 Ferro Therapeutics, Inc. Pyrido-indole analogues as gpx4 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
FR2282891B1 (fr) 1980-03-28
DD121789A5 (fr) 1976-08-20
LU73263A1 (fr) 1977-04-15
ATA663375A (de) 1978-10-15
IL47975A (en) 1980-05-30
FR2282891A1 (fr) 1976-03-26
ZA755480B (en) 1976-07-28
ES440509A1 (es) 1977-06-01
DE2441261A1 (de) 1976-03-18
IE42218L (en) 1976-02-28
IL47975A0 (en) 1975-11-25
OA05094A (fr) 1981-01-31
CH623584A5 (fr) 1981-06-15
CH617934A5 (fr) 1980-06-30
DK386175A (da) 1976-02-29
BE832735A (nl) 1976-02-25
AT350055B (de) 1979-05-10
GB1479235A (en) 1977-07-06
IE42218B1 (en) 1980-07-02
FI752411A (fr) 1976-02-29
AU8410675A (en) 1977-02-24
NO752939L (fr) 1976-03-02
US4051243A (en) 1977-09-27
CH624113A5 (fr) 1981-07-15
JPS5168595A (en) 1976-06-14
NL7510173A (nl) 1976-03-02
PH12677A (en) 1979-07-11
EG12384A (en) 1980-03-31

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