NO342302B1 - Tenekteplase for anvendelse ved behandling av akutt, iskemisk slag hos et menneske - Google Patents

Tenekteplase for anvendelse ved behandling av akutt, iskemisk slag hos et menneske Download PDF

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Publication number
NO342302B1
NO342302B1 NO20091296A NO20091296A NO342302B1 NO 342302 B1 NO342302 B1 NO 342302B1 NO 20091296 A NO20091296 A NO 20091296A NO 20091296 A NO20091296 A NO 20091296A NO 342302 B1 NO342302 B1 NO 342302B1
Authority
NO
Norway
Prior art keywords
tenecteplase
stroke
bolus
minutes
dose
Prior art date
Application number
NO20091296A
Other languages
English (en)
Norwegian (no)
Other versions
NO20091296L (no
Inventor
Peter Kuebler
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38835003&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO342302(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO20091296L publication Critical patent/NO20091296L/no
Publication of NO342302B1 publication Critical patent/NO342302B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20091296A 2006-08-29 2009-03-27 Tenekteplase for anvendelse ved behandling av akutt, iskemisk slag hos et menneske NO342302B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82386806P 2006-08-29 2006-08-29
PCT/US2007/074997 WO2008027687A2 (en) 2006-08-29 2007-08-01 Use of tenecteplase for treating acute ischemic stroke

Publications (2)

Publication Number Publication Date
NO20091296L NO20091296L (no) 2009-05-28
NO342302B1 true NO342302B1 (no) 2018-04-30

Family

ID=38835003

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091296A NO342302B1 (no) 2006-08-29 2009-03-27 Tenekteplase for anvendelse ved behandling av akutt, iskemisk slag hos et menneske

Country Status (21)

Country Link
US (2) US20080107641A1 (cg-RX-API-DMAC10.html)
EP (1) EP2056856B1 (cg-RX-API-DMAC10.html)
JP (1) JP5785687B2 (cg-RX-API-DMAC10.html)
KR (1) KR20090045405A (cg-RX-API-DMAC10.html)
CN (1) CN101505785A (cg-RX-API-DMAC10.html)
AU (1) AU2007290277B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0716143A2 (cg-RX-API-DMAC10.html)
CA (1) CA2661012C (cg-RX-API-DMAC10.html)
CO (1) CO6150188A2 (cg-RX-API-DMAC10.html)
EA (1) EA015573B1 (cg-RX-API-DMAC10.html)
EC (1) ECSP099178A (cg-RX-API-DMAC10.html)
IL (2) IL196987A (cg-RX-API-DMAC10.html)
MX (1) MX2009001918A (cg-RX-API-DMAC10.html)
MY (1) MY163119A (cg-RX-API-DMAC10.html)
NO (1) NO342302B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ574767A (cg-RX-API-DMAC10.html)
SG (3) SG10201501498VA (cg-RX-API-DMAC10.html)
TW (1) TWI439282B (cg-RX-API-DMAC10.html)
UA (1) UA97486C2 (cg-RX-API-DMAC10.html)
WO (1) WO2008027687A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200900957B (cg-RX-API-DMAC10.html)

Families Citing this family (26)

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US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
UA95903C2 (ru) 2005-02-24 2011-09-26 Дифьюжен Фармасьютикалз Ллк Транс-каротиноиды, их синтез, лекарственная форма и применение
TWI439282B (zh) 2006-08-29 2014-06-01 Genentech Inc 以血栓溶解劑治療中風之方法
EP3483140A1 (en) 2007-04-13 2019-05-15 Diffusion Pharmaceuticals LLC Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
US9034007B2 (en) 2007-09-21 2015-05-19 Insera Therapeutics, Inc. Distal embolic protection devices with a variable thickness microguidewire and methods for their use
EP2384141A1 (en) * 2008-12-24 2011-11-09 Koninklijke Philips Electronics N.V. System, method and apparatus for cardiac intervention with mr stroke detection and treatment
KR101875843B1 (ko) 2009-06-22 2018-07-06 디퓨젼 파마슈티컬즈 엘엘씨 확산 촉진 화합물 및 그 화합물 단독 또는 혈전 용해제와 합쳐진 화합물의 용도
CA2772097C (en) * 2009-08-24 2019-04-30 Hough Ear Institute Methods for treating acute acoustic trauma
CN105287473A (zh) 2010-06-02 2016-02-03 扩散药品有限公司 包含双极性反式类胡萝卜素的组合物及其应用
EP2654770B1 (en) * 2010-12-23 2018-07-11 Gennova Biopharmaceuticals Ltd. Pharmaceutical compositions of tenecteplase
WO2014062888A1 (en) * 2012-10-18 2014-04-24 University Of South Florida Compositions and methods for treating stroke
US8679150B1 (en) 2013-03-15 2014-03-25 Insera Therapeutics, Inc. Shape-set textile structure based mechanical thrombectomy methods
US8715314B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment measurement methods
CA2901443A1 (en) 2013-03-15 2014-09-25 Insera Therapeutics, Inc. Vascular treatment devices and methods
US8715315B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment systems
US10220008B2 (en) 2013-08-14 2019-03-05 Stc.Unm Treatment and prevention of stroke and other neurological disorders
DK3209767T3 (da) * 2014-10-21 2020-11-02 Gennova Biopharmaceuticals Ltd Hidtil ukendt oprensningsfremgangsmåde til isolering og kommerciel fremstilling af rekombinant tnk-tpa (tenecteplase)
EP3416568A4 (en) 2016-02-16 2019-10-16 Insera Therapeutics, Inc. SUCTION DEVICES AND ANCHORED FLOW REVERSING DEVICES
WO2017165667A1 (en) 2016-03-24 2017-09-28 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
US12458379B2 (en) * 2017-01-24 2025-11-04 Boston Scientific Scimed, Inc. Method for the treatment of thromboembolism
WO2018210860A1 (en) * 2017-05-16 2018-11-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of acute ischemic stroke
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
WO2021158799A1 (en) * 2020-02-04 2021-08-12 The Regents Of The University Of Colorado, A Body Corporate Prophylactic uses of annexin a2
CA3171307A1 (en) * 2020-02-19 2021-08-26 Nono Inc. Combination treatment of stroke with plasmin-cleavable psd-95 inhibitor and reperfusion
CN114984197A (zh) * 2022-07-01 2022-09-02 江苏丰华生物制药有限公司 替奈普酶在制备用于治疗急性缺血性卒中的药物组合物中的应用
CN115487294A (zh) * 2022-07-12 2022-12-20 上海丰华天力通生物医药有限公司 替奈普酶在制备用于治疗轻型缺血性卒中的药物组合物中的应用

Citations (1)

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US20030180282A1 (en) * 2002-03-25 2003-09-25 Victor Serebruany Method of treatment of thrombotic events

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US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
JP3559559B2 (ja) 1992-06-03 2004-09-02 ジェネンテク,インコーポレイテッド 向上した治療特性を有する組織プラスミノーゲン活性化因子グリコシル化変異体
JP2002173447A (ja) * 2000-09-29 2002-06-21 Yamanouchi Pharmaceut Co Ltd 脳塞栓症治療用医薬組成物
US7084118B2 (en) * 2002-02-22 2006-08-01 Genentech, Inc. Combination treatment with t-PA variant and low molecular weight heparin
US20070014779A1 (en) * 2002-11-14 2007-01-18 Genentech, Inc. Plasminogen activator variant formulations
WO2006094120A2 (en) * 2005-03-02 2006-09-08 The Regents Of The University Of California Treatment for embolic stroke
TWI439282B (zh) 2006-08-29 2014-06-01 Genentech Inc 以血栓溶解劑治療中風之方法

Patent Citations (1)

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US20030180282A1 (en) * 2002-03-25 2003-09-25 Victor Serebruany Method of treatment of thrombotic events

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HALEY, C.E. et al., A pilot dose-escalation safety study of Tenecteplase in acute ischemic stroke, 2005, Stroke, vol. 36, nr. 3, side 607-612 ISSN: 0039-2499., Dated: 01.01.0001 *
KEYT, B. A. et al., A faster-acting and more potent form of tissue plasminogen activator, 1994, Proc. Natl. Acad. Sci., USA, vol. 91, nr. 9, side 3670-3674, ISSN: 0027-8424., Dated: 01.01.0001 *
SEMBA, C. P., et al., Alteplase and tenecteplase: applications in the peripheral circulation, 2001, Tech Vasc Interv Radiol., vol.4, nr. 2, side 99-106., Dated: 01.01.0001 *
ZHANG, R.L., et al., Postischemic intracarotid treatment with TNK-tPA reduces infarct volume and improves neurological deficits in embolic stroke in the unanesthetized rat, 2000, Brain Res., vol. 878, nr. 1-2, side 64-71, ISSN: 0006-8993. , Dated: 01.01.0001 *

Also Published As

Publication number Publication date
CN101505785A (zh) 2009-08-12
IL248176A0 (en) 2016-11-30
TW200817033A (en) 2008-04-16
CA2661012C (en) 2019-03-19
US9023346B2 (en) 2015-05-05
CO6150188A2 (es) 2010-04-20
US20120164157A1 (en) 2012-06-28
EP2056856A2 (en) 2009-05-13
KR20090045405A (ko) 2009-05-07
SG174753A1 (en) 2011-10-28
MX2009001918A (es) 2009-03-06
TWI439282B (zh) 2014-06-01
BRPI0716143A2 (pt) 2013-11-26
EA015573B1 (ru) 2011-10-31
IL196987A0 (en) 2011-08-01
WO2008027687A2 (en) 2008-03-06
AU2007290277A1 (en) 2008-03-06
WO2008027687A3 (en) 2008-05-22
SG10201501498VA (en) 2015-04-29
JP2010502629A (ja) 2010-01-28
ZA200900957B (en) 2010-05-26
AU2007290277B2 (en) 2013-04-11
ECSP099178A (es) 2009-06-30
IL196987A (en) 2016-10-31
MY163119A (en) 2017-08-15
US20080107641A1 (en) 2008-05-08
CA2661012A1 (en) 2008-03-06
JP5785687B2 (ja) 2015-09-30
SG10201804944XA (en) 2018-07-30
UA97486C2 (ru) 2012-02-27
HK1131054A1 (en) 2010-01-15
NO20091296L (no) 2009-05-28
EP2056856B1 (en) 2015-01-14
EA200970237A1 (ru) 2009-08-28
NZ574767A (en) 2012-02-24

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