NO332309B1 - Antagonister av CXCRX3-bindene CXC-kjemokiner, samt fremgangsmate for fremstilling derav, DNA molekyler kodende for nevnte antagonister, ekspresjonsvektor, vertcelle, farmasoytisk preparat og anvendelse av nevnte antagonister. - Google Patents

Antagonister av CXCRX3-bindene CXC-kjemokiner, samt fremgangsmate for fremstilling derav, DNA molekyler kodende for nevnte antagonister, ekspresjonsvektor, vertcelle, farmasoytisk preparat og anvendelse av nevnte antagonister. Download PDF

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Publication number
NO332309B1
NO332309B1 NO20050162A NO20050162A NO332309B1 NO 332309 B1 NO332309 B1 NO 332309B1 NO 20050162 A NO20050162 A NO 20050162A NO 20050162 A NO20050162 A NO 20050162A NO 332309 B1 NO332309 B1 NO 332309B1
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Norway
Prior art keywords
cxcl11
antagonists
cxcr3
sequence
binding
Prior art date
Application number
NO20050162A
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English (en)
Norwegian (no)
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NO20050162L (no
Inventor
Amanda Proudfoot
Marie Kosco-Vilbois
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Merck Serono Sa
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Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of NO20050162L publication Critical patent/NO20050162L/no
Publication of NO332309B1 publication Critical patent/NO332309B1/no

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    • C07ORGANIC CHEMISTRY
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/522Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • AHUMAN NECESSITIES
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  • Proteomics, Peptides & Aminoacids (AREA)
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NO20050162A 2002-06-12 2005-01-12 Antagonister av CXCRX3-bindene CXC-kjemokiner, samt fremgangsmate for fremstilling derav, DNA molekyler kodende for nevnte antagonister, ekspresjonsvektor, vertcelle, farmasoytisk preparat og anvendelse av nevnte antagonister. NO332309B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02100697 2002-06-12
PCT/EP2003/050211 WO2003106488A2 (en) 2002-06-12 2003-06-03 Novel antagonists of cxcr3-binding cxc chemokines

Publications (2)

Publication Number Publication Date
NO20050162L NO20050162L (no) 2005-01-12
NO332309B1 true NO332309B1 (no) 2012-08-20

Family

ID=29724537

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050162A NO332309B1 (no) 2002-06-12 2005-01-12 Antagonister av CXCRX3-bindene CXC-kjemokiner, samt fremgangsmate for fremstilling derav, DNA molekyler kodende for nevnte antagonister, ekspresjonsvektor, vertcelle, farmasoytisk preparat og anvendelse av nevnte antagonister.

Country Status (16)

Country Link
US (1) US7541435B2 (es)
EP (1) EP1515990B1 (es)
JP (1) JP4394569B2 (es)
AR (1) AR040200A1 (es)
AT (1) ATE359297T1 (es)
AU (1) AU2003255505B2 (es)
CA (1) CA2489298C (es)
CY (1) CY1106799T1 (es)
DE (1) DE60313168T2 (es)
DK (1) DK1515990T3 (es)
ES (1) ES2282666T3 (es)
IL (1) IL165727A (es)
NO (1) NO332309B1 (es)
PT (1) PT1515990E (es)
SI (1) SI1515990T1 (es)
WO (1) WO2003106488A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964194B2 (en) * 2002-11-15 2011-06-21 Morehouse School Of Medicine Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation
AU2005219322B2 (en) * 2004-03-09 2008-09-18 Kyoto University Pharmaceutical Composition Comprising CXCR3 Inhibitor
ITFI20040243A1 (it) * 2004-11-25 2005-02-25 Paola Romagnani Metodo diagnostico per la previsione di rigetto di organo trapiantato
WO2006069449A1 (en) * 2004-12-29 2006-07-06 The University Of British Columbia Chemokine receptor-independent immunomodulatory and anti-proliferative activity
JP2008545396A (ja) * 2005-05-18 2008-12-18 インターミューン インコーポレイテッド 非天然ケモカイン受容体リガンドおよびこれらの使用方法
EP2136832B1 (en) 2007-03-26 2015-09-02 General Regeneratives Limited Methods for promoting protection and regeneration of bone marrow using cxcl9 and anti-cxcl9 antibodies
EP2164508B1 (en) * 2007-06-04 2014-01-08 Rappaport Family Institute for Research in the Medical Sciences Agents for the treatment of inflammatory diseases and methods of using same
WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration
US10983128B2 (en) 2015-02-05 2021-04-20 Bristol-Myers Squibb Company CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy
JP2018521959A (ja) * 2015-04-29 2018-08-09 サンフォード−バーナム メディカル リサーチ インスティテュート Btlaアゴニスト抗体を用いた免疫応答のモジュレーション
EP4252629A3 (en) 2016-12-07 2023-12-27 Biora Therapeutics, Inc. Gastrointestinal tract detection methods, devices and systems
EP3554541B1 (en) 2016-12-14 2023-06-07 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
KR20210095165A (ko) 2018-11-19 2021-07-30 프로제너티, 인크. 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스
CN115666704A (zh) 2019-12-13 2023-01-31 比奥拉治疗股份有限公司 用于将治疗剂递送至胃肠道的可摄取装置
GB202214951D0 (en) * 2022-10-11 2022-11-23 Univ London Queen Mary CXC receptor ligands

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
US5656724A (en) * 1994-10-26 1997-08-12 Repligen Corporation Chemokine-like proteins and methods of use
US5707829A (en) * 1995-08-11 1998-01-13 Genetics Institute, Inc. DNA sequences and secreted proteins encoded thereby
US6140064A (en) * 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
US5977334A (en) * 1997-09-11 1999-11-02 The Cleveland Clinic Foundation DNA encoding a chemokine, Beta R1, comprising the Beta R1 promoter
US20020018776A1 (en) * 2000-04-14 2002-02-14 Millennium Pharmaceuticals, Inc. Method of treating graft rejection using inhibitors of CXCR3 function
AU2001273387A1 (en) * 2000-07-12 2002-01-21 Gryphon Therapeutics, Inc. Polymer-modified bioactive synthetic chemokines, and methods for their manufacture and use
CA2430401A1 (en) 2000-12-01 2002-06-06 Schering Corporation Uses of mammalian genes and related reagents

Also Published As

Publication number Publication date
EP1515990A2 (en) 2005-03-23
CY1106799T1 (el) 2012-10-24
ES2282666T3 (es) 2007-10-16
JP4394569B2 (ja) 2010-01-06
CA2489298C (en) 2012-09-11
ATE359297T1 (de) 2007-05-15
JP2006511200A (ja) 2006-04-06
WO2003106488A2 (en) 2003-12-24
AU2003255505B2 (en) 2009-01-08
US7541435B2 (en) 2009-06-02
EP1515990B1 (en) 2007-04-11
WO2003106488A3 (en) 2004-04-15
NO20050162L (no) 2005-01-12
IL165727A (en) 2010-05-17
US20060204498A1 (en) 2006-09-14
CA2489298A1 (en) 2003-12-24
PT1515990E (pt) 2007-05-31
DE60313168D1 (de) 2007-05-24
DE60313168T2 (de) 2007-12-20
DK1515990T3 (da) 2007-06-11
AR040200A1 (es) 2005-03-16
SI1515990T1 (sl) 2007-08-31
IL165727A0 (en) 2006-01-15
AU2003255505A1 (en) 2003-12-31

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