NO331426B1 - Palladium-substituert bakterioklorofyll derivat, farmasoytisk sammensetning, fremgangsmater for fremstilling samt anvendelse av nevnte derivat - Google Patents

Palladium-substituert bakterioklorofyll derivat, farmasoytisk sammensetning, fremgangsmater for fremstilling samt anvendelse av nevnte derivat Download PDF

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Publication number
NO331426B1
NO331426B1 NO20012807A NO20012807A NO331426B1 NO 331426 B1 NO331426 B1 NO 331426B1 NO 20012807 A NO20012807 A NO 20012807A NO 20012807 A NO20012807 A NO 20012807A NO 331426 B1 NO331426 B1 NO 331426B1
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Norway
Prior art keywords
bpheid
compound
formula
cells
preparation
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Application number
NO20012807A
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English (en)
Norwegian (no)
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NO20012807L (no
NO20012807D0 (no
Inventor
Avigdor Scherz
Yoram Salomon
Hugo Scheer
Alexander Brandis
Original Assignee
Yeda Res & Dev
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Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO20012807D0 publication Critical patent/NO20012807D0/no
Publication of NO20012807L publication Critical patent/NO20012807L/no
Publication of NO331426B1 publication Critical patent/NO331426B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20012807A 1998-12-09 2001-06-07 Palladium-substituert bakterioklorofyll derivat, farmasoytisk sammensetning, fremgangsmater for fremstilling samt anvendelse av nevnte derivat NO331426B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98403110 1998-12-09
PCT/IL1999/000673 WO2000033833A1 (en) 1998-12-09 1999-12-09 Palladium-substituted bacteriochlorophyll derivatives and use thereof

Publications (3)

Publication Number Publication Date
NO20012807D0 NO20012807D0 (no) 2001-06-07
NO20012807L NO20012807L (no) 2001-08-08
NO331426B1 true NO331426B1 (no) 2011-12-27

Family

ID=8235584

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012807A NO331426B1 (no) 1998-12-09 2001-06-07 Palladium-substituert bakterioklorofyll derivat, farmasoytisk sammensetning, fremgangsmater for fremstilling samt anvendelse av nevnte derivat

Country Status (22)

Country Link
US (1) US6569846B1 (xx)
EP (1) EP1137411B1 (xx)
JP (1) JP4796227B2 (xx)
CN (1) CN1160069C (xx)
AT (1) ATE347554T1 (xx)
AU (1) AU771292B2 (xx)
BR (1) BRPI9916096B8 (xx)
CA (1) CA2353554C (xx)
CY (1) CY1106450T1 (xx)
DE (1) DE69934328T2 (xx)
DK (1) DK1137411T3 (xx)
ES (1) ES2277454T3 (xx)
HK (1) HK1040638B (xx)
HU (1) HU228208B1 (xx)
IL (1) IL143591A0 (xx)
NO (1) NO331426B1 (xx)
NZ (1) NZ512093A (xx)
PL (1) PL201172B1 (xx)
PT (1) PT1137411E (xx)
RU (1) RU2234508C2 (xx)
SI (1) SI1137411T1 (xx)
WO (1) WO2000033833A1 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
WO2002013820A1 (en) * 2000-08-11 2002-02-21 Ceramoptec Industries, Inc. Photosensitizing ointment
EP1277470A1 (fr) * 2001-07-17 2003-01-22 Steba Biotech N.V. Formulation galénique injectable pour utilisation dans un diagnostic ou une thérapie photodynamique et son procédé de préparation
AU2003230164B2 (en) * 2002-05-08 2008-05-01 Yeda Research And Development Co. Ltd. Sensitized online BOLD-MRI imaging method
JP4529344B2 (ja) * 2002-06-03 2010-08-25 ニプロ株式会社 腫瘍組織の酸素濃度を上昇させるためのポルフィリン酸素輸液製剤
DE60328496D1 (en) 2002-06-27 2009-09-03 Health Research Inc Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
EP1606291A2 (en) * 2002-07-02 2005-12-21 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its dervatives
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
EP2322173B1 (en) * 2004-06-07 2016-08-10 Yeda Research And Development Co., Ltd. Cationic bacteriochlorophyll derivatives and uses thereof
US20060222592A1 (en) * 2005-04-05 2006-10-05 Clemens Burda Nanoparticles and methods of manufacturing nanoparticles for electronic and non-electronic applications
US20110040170A1 (en) * 2008-01-28 2011-02-17 Yeda Research And Development Co., Ltd. Endoscopic imaging photodynamic therapy system and methods of use
AU2009219682B2 (en) 2008-02-27 2015-06-18 Yeda Research & Development Co. Ltd RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors
US20120034157A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
EP2425873A1 (fr) 2010-09-07 2012-03-07 Steba Maor SA Modélisation de l'action d'une fibre optique dans un traitement par therapie photodynamique, et assistance à la planification d'un tel traitement
CN103405769A (zh) * 2013-03-07 2013-11-27 北京亿仁赛博医疗科技研发中心有限公司 光敏剂在制备治疗疾病的病毒灭活药物中的应用
CA2905109C (en) 2013-03-11 2021-03-16 Tookad Ip Sarl Method for producing bacteriochlorophyll a
CA2907356C (en) 2013-03-15 2022-07-12 Sherri Ann MCFARLAND Metal-based coordination complexes as photodynamic compounds and their use
AU2017250732B2 (en) 2016-04-10 2022-11-10 Memorial Sloan-Kettering Cancer Center Combinational therapies for treatment of cancer comprising a bacteriochlorophyll derivative
US10933134B2 (en) 2017-03-16 2021-03-02 Memorial Sloan Kettering Cancer Center Combination therapies for treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002962A (en) 1988-07-20 1991-03-26 Health Research, Inc. Photosensitizing agents
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
IL102645A (en) 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
IL116126A0 (en) * 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
IL143591A0 (en) 2002-04-21
CA2353554A1 (en) 2000-06-15
US6569846B1 (en) 2003-05-27
EP1137411A4 (en) 2003-04-23
BR9916096A (pt) 2001-11-13
ATE347554T1 (de) 2006-12-15
JP4796227B2 (ja) 2011-10-19
WO2000033833A1 (en) 2000-06-15
EP1137411A1 (en) 2001-10-04
NO20012807L (no) 2001-08-08
DK1137411T3 (da) 2007-03-26
DE69934328D1 (de) 2007-01-18
HK1040638A1 (en) 2002-06-21
BR9916096B1 (pt) 2013-11-19
ES2277454T3 (es) 2007-07-01
CY1106450T1 (el) 2011-10-12
AU771292B2 (en) 2004-03-18
CA2353554C (en) 2011-04-26
CN1334728A (zh) 2002-02-06
RU2234508C2 (ru) 2004-08-20
HU228208B1 (en) 2013-01-28
SI1137411T1 (sl) 2007-10-31
AU1583400A (en) 2000-06-26
BRPI9916096B8 (pt) 2021-05-25
HUP0105411A2 (hu) 2002-04-29
HUP0105411A3 (en) 2003-12-29
HK1040638B (zh) 2007-06-15
JP2002531497A (ja) 2002-09-24
PL348201A1 (en) 2002-05-06
NZ512093A (en) 2003-04-29
PT1137411E (pt) 2007-02-28
CN1160069C (zh) 2004-08-04
PL201172B1 (pl) 2009-03-31
EP1137411B1 (en) 2006-12-06
NO20012807D0 (no) 2001-06-07
DE69934328T2 (de) 2007-07-19

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