NO331343B1 - Fremgangsmate og system for kvantitativ bestemmelse av hemoglobin i uhemolysert helblod - Google Patents
Fremgangsmate og system for kvantitativ bestemmelse av hemoglobin i uhemolysert helblod Download PDFInfo
- Publication number
- NO331343B1 NO331343B1 NO20033690A NO20033690A NO331343B1 NO 331343 B1 NO331343 B1 NO 331343B1 NO 20033690 A NO20033690 A NO 20033690A NO 20033690 A NO20033690 A NO 20033690A NO 331343 B1 NO331343 B1 NO 331343B1
- Authority
- NO
- Norway
- Prior art keywords
- sample
- wavelength
- hemoglobin
- absorption
- light
- Prior art date
Links
- 108010054147 Hemoglobins Proteins 0.000 title claims abstract description 72
- 102000001554 Hemoglobins Human genes 0.000 title claims abstract description 72
- 210000004369 blood Anatomy 0.000 title claims abstract description 45
- 239000008280 blood Substances 0.000 title claims abstract description 45
- 238000000034 method Methods 0.000 title claims abstract description 41
- 238000010521 absorption reaction Methods 0.000 claims abstract description 106
- 238000005259 measurement Methods 0.000 claims abstract description 97
- 238000012545 processing Methods 0.000 claims abstract description 24
- 230000001419 dependent effect Effects 0.000 claims abstract description 8
- 230000003287 optical effect Effects 0.000 claims description 23
- 238000002835 absorbance Methods 0.000 claims description 19
- 238000001514 detection method Methods 0.000 claims description 6
- 238000012937 correction Methods 0.000 claims description 4
- 230000035945 sensitivity Effects 0.000 claims description 4
- 239000006185 dispersion Substances 0.000 claims description 3
- 230000009102 absorption Effects 0.000 description 82
- 239000003153 chemical reaction reagent Substances 0.000 description 11
- 239000003795 chemical substances by application Substances 0.000 description 8
- 238000010586 diagram Methods 0.000 description 6
- 238000000149 argon plasma sintering Methods 0.000 description 5
- 210000003743 erythrocyte Anatomy 0.000 description 5
- 238000011156 evaluation Methods 0.000 description 5
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 description 4
- 238000002834 transmittance Methods 0.000 description 4
- 108010061951 Methemoglobin Proteins 0.000 description 3
- 108010064719 Oxyhemoglobins Proteins 0.000 description 3
- 108010002255 deoxyhemoglobin Proteins 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 2
- 239000012042 active reagent Substances 0.000 description 2
- 150000001540 azides Chemical class 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000001447 compensatory effect Effects 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000691 measurement method Methods 0.000 description 2
- -1 oxy- Chemical class 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000004445 quantitative analysis Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 235000010288 sodium nitrite Nutrition 0.000 description 2
- 108010003320 Carboxyhemoglobin Proteins 0.000 description 1
- 206010018913 Haemolyses Diseases 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 108010016811 Sulfhemoglobin Proteins 0.000 description 1
- 238000011481 absorbance measurement Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229960003964 deoxycholic acid Drugs 0.000 description 1
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 1
- 239000002274 desiccant Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007430 reference method Methods 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0104443A SE0104443D0 (sv) | 2001-12-28 | 2001-12-28 | Analysis method and cuvette therefor |
| PCT/SE2002/002412 WO2003056327A1 (en) | 2001-12-28 | 2002-12-20 | Method for quantitative hemoglobin determination in undiluted unhemolyzed whole blood |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20033690D0 NO20033690D0 (no) | 2003-08-20 |
| NO20033690L NO20033690L (no) | 2003-10-28 |
| NO331343B1 true NO331343B1 (no) | 2011-12-05 |
Family
ID=20286538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20033690A NO331343B1 (no) | 2001-12-28 | 2003-08-20 | Fremgangsmate og system for kvantitativ bestemmelse av hemoglobin i uhemolysert helblod |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6831733B2 (de) |
| EP (2) | EP1698883B1 (de) |
| JP (2) | JP4532905B2 (de) |
| KR (1) | KR100953472B1 (de) |
| CN (1) | CN100498336C (de) |
| AT (2) | ATE496289T1 (de) |
| AU (1) | AU2002359193B2 (de) |
| BR (1) | BRPI0207671B8 (de) |
| CA (1) | CA2468513C (de) |
| DE (2) | DE60212444T2 (de) |
| DK (2) | DK1456649T3 (de) |
| ES (2) | ES2362499T3 (de) |
| MX (1) | MXPA04006323A (de) |
| NO (1) | NO331343B1 (de) |
| PL (1) | PL211569B1 (de) |
| PT (1) | PT1456649E (de) |
| RU (1) | RU2302638C2 (de) |
| SE (1) | SE0104443D0 (de) |
| SI (1) | SI1698883T1 (de) |
| WO (1) | WO2003056327A1 (de) |
| ZA (1) | ZA200403916B (de) |
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| CA2460898A1 (en) * | 2004-03-09 | 2005-09-09 | James Samsoondar | Apparatus and method for combining in vivo and in vitro testing |
| US8206650B2 (en) * | 2005-04-12 | 2012-06-26 | Chromedx Inc. | Joint-diagnostic spectroscopic and biosensor meter |
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| CA2507323A1 (en) * | 2005-05-13 | 2006-11-13 | Chromedx Inc. | Diagnostic whole blood and plasma apparatus |
| US7740804B2 (en) * | 2005-04-12 | 2010-06-22 | Chromedx Inc. | Spectroscopic sample holder |
| US20100245803A1 (en) * | 2005-04-12 | 2010-09-30 | Chromedx Inc. | Blood sample holder for spectroscopic analysis |
| CA2517299A1 (en) * | 2005-08-26 | 2007-02-26 | Chromedx Inc. | Hollow needle assembly |
| US7426407B2 (en) * | 2005-09-13 | 2008-09-16 | Edwards Lifesciences Corp | Continuous spectroscopic measurement of total hemoglobin |
| SE530244C2 (sv) * | 2006-05-05 | 2008-04-08 | Hemocue Ab | Förfarande och system för kvantitativ hemoglobinbestämning |
| US7738094B2 (en) | 2007-01-26 | 2010-06-15 | Becton, Dickinson And Company | Method, system, and compositions for cell counting and analysis |
| US8582106B2 (en) * | 2007-11-09 | 2013-11-12 | Hach Company | Automatic optical measurement system and method |
| KR101423770B1 (ko) * | 2008-01-08 | 2014-07-25 | 엘지전자 주식회사 | 전혈과 용혈에 의한 헤모글로빈의 정량적 측정 방법 및측정 장치 |
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| KR101247371B1 (ko) * | 2009-11-24 | 2013-03-26 | 연세대학교 산학협력단 | 적혈구의 광열효과를 이용한 세포 내외부 헤모글로빈의 차이 측정방법 |
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| US8730460B2 (en) * | 2011-04-08 | 2014-05-20 | William Marsh Rice University | Paper based spectrophotometric detection of blood hemoglobin concentration |
| CN103917870B (zh) | 2011-11-16 | 2016-04-13 | 贝克顿·迪金森公司 | 用于检测样品中的分析物的方法和系统 |
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| KR101608684B1 (ko) | 2012-04-13 | 2016-04-05 | 바디텍메드(주) | 헤모글로빈 측정 장치 및 방법 |
| US9081001B2 (en) | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| IN2012DE02074A (de) | 2012-07-03 | 2015-08-14 | Srivastava Ambar | |
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| CN105408745B (zh) * | 2013-05-09 | 2018-10-23 | 艾博特健康公司 | 确定未裂解血液样本中基于血红蛋白的参数的方法和装置 |
| EP2994042B1 (de) * | 2013-05-10 | 2023-09-27 | University Of Utah Research Foundation | Vorrichtungen, systeme und verfahren zur messung von blutverlust |
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| ES2688270T3 (es) | 2015-03-10 | 2018-10-31 | Becton, Dickinson And Company | Dispositivo de gestión de micromuestras de fluidos biológicos |
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| CN104931441A (zh) * | 2015-06-15 | 2015-09-23 | 马国鹭 | 一种快速测量血红蛋白的方法和装置 |
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| CN108240973A (zh) * | 2018-01-23 | 2018-07-03 | 江苏康尚生物医疗科技有限公司 | 一种全血血红蛋白浓度检测方法及装置 |
| CN109239016B (zh) * | 2018-09-11 | 2021-03-26 | 深圳市国赛生物技术有限公司 | 血液样本检测方法、装置及可读存储介质 |
| KR102168852B1 (ko) * | 2019-05-07 | 2020-10-22 | 주식회사 체리센스 | 혈중 헤모글로빈 측정 장치 |
| CN110584678A (zh) * | 2019-09-06 | 2019-12-20 | 广东宝莱特医用科技股份有限公司 | 一种血容量变化率的测量方法和装置 |
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| SE399768B (sv) | 1975-09-29 | 1978-02-27 | Lilja Jan E | Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet |
| DK282085D0 (da) * | 1985-06-21 | 1985-06-21 | Radiometer As | Fremgangsmaade og apparat til bestemmelse af blodkomponenter |
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-
2001
- 2001-12-28 SE SE0104443A patent/SE0104443D0/xx unknown
-
2002
- 2002-12-20 DE DE60212444T patent/DE60212444T2/de not_active Expired - Lifetime
- 2002-12-20 DK DK02793712T patent/DK1456649T3/da active
- 2002-12-20 EP EP06115338A patent/EP1698883B1/de not_active Expired - Lifetime
- 2002-12-20 PL PL369207A patent/PL211569B1/pl unknown
- 2002-12-20 DE DE60239019T patent/DE60239019D1/de not_active Expired - Lifetime
- 2002-12-20 AU AU2002359193A patent/AU2002359193B2/en not_active Expired
- 2002-12-20 ZA ZA200403916A patent/ZA200403916B/en unknown
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- 2002-12-20 DK DK06115338.3T patent/DK1698883T3/da active
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