NO331012B1 - N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler - Google Patents

N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler

Info

Publication number
NO331012B1
NO331012B1 NO20052788A NO20052788A NO331012B1 NO 331012 B1 NO331012 B1 NO 331012B1 NO 20052788 A NO20052788 A NO 20052788A NO 20052788 A NO20052788 A NO 20052788A NO 331012 B1 NO331012 B1 NO 331012B1
Authority
NO
Norway
Prior art keywords
methyleneamino
pyridones
sulfonyl
hydroxy
antimicrobial agents
Prior art date
Application number
NO20052788A
Other languages
English (en)
Norwegian (no)
Other versions
NO20052788L (no
Inventor
Rodney Dean Bush
Namal Chithranga Warshakoon
Original Assignee
Warner Chilcott Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Chilcott Co Llc filed Critical Warner Chilcott Co Llc
Publication of NO20052788L publication Critical patent/NO20052788L/no
Publication of NO331012B1 publication Critical patent/NO331012B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20052788A 2002-11-09 2005-06-09 N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler NO331012B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42507102P 2002-11-09 2002-11-09
PCT/US2003/035623 WO2004043928A2 (en) 2002-11-09 2003-11-07 N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobial agents

Publications (2)

Publication Number Publication Date
NO20052788L NO20052788L (no) 2005-06-09
NO331012B1 true NO331012B1 (no) 2011-09-05

Family

ID=32312927

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052788A NO331012B1 (no) 2002-11-09 2005-06-09 N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler

Country Status (25)

Country Link
US (3) US6946479B2 (ja)
EP (1) EP1558580B1 (ja)
JP (1) JP4327730B2 (ja)
KR (2) KR100894237B1 (ja)
CN (1) CN1708482A (ja)
AT (1) ATE372986T1 (ja)
AU (1) AU2003296045B2 (ja)
BR (1) BR0316086A (ja)
CA (1) CA2502416C (ja)
CO (1) CO5570702A2 (ja)
CY (1) CY1106957T1 (ja)
DE (1) DE60316339T2 (ja)
DK (1) DK1558580T3 (ja)
ES (1) ES2293059T3 (ja)
HR (1) HRP20050517B1 (ja)
IL (1) IL168118A (ja)
MA (1) MA27549A1 (ja)
MX (1) MXPA05004897A (ja)
NO (1) NO331012B1 (ja)
NZ (1) NZ539385A (ja)
PL (1) PL377176A1 (ja)
PT (1) PT1558580E (ja)
RU (1) RU2321584C2 (ja)
WO (1) WO2004043928A2 (ja)
ZA (1) ZA200503682B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6930117B2 (en) * 2002-11-09 2005-08-16 The Procter & Gamble Company N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones
US6946479B2 (en) * 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones
US20070275944A1 (en) * 2006-04-05 2007-11-29 The Board Of Trustees Operating Michigan State University Antioxidants and methods of their use
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
MX2011007420A (es) 2009-07-06 2011-12-14 Akebia Therapeutics Inc Compuestos, composiciones y metodos para prevenir la metastasis de las celulas cancerigenas.
CN102595896B (zh) * 2009-11-06 2016-02-17 爱尔皮奥治疗有限公司 提高低氧诱导因子-1α的稳定性的方法
JP6118808B2 (ja) 2011-10-31 2017-04-19 ザ メソジスト ホスピタル リサーチ インスティテュート ヒトグリオームを治療するためのmao標的化/探索部分を含む化合物
CN103360308A (zh) * 2012-03-28 2013-10-23 孙伟新 1,4-二羟基-6-甲基-2-吡啶酮类化合物及其制备方法和用途
US20150050277A1 (en) 2013-03-15 2015-02-19 Aerpio Therapeutics Inc. Compositions and methods for treating ocular diseases
MX371382B (es) 2013-03-15 2020-01-28 Aerpio Therapeutics Inc Composiciones, formulaciones y metodos para tratar enfermedades oculares.
CN106232120B (zh) 2014-02-19 2021-01-08 爱尔皮奥治疗有限公司 制备n-苄基-3-羟基-4-取代的-吡啶-2-(1h)-酮的方法
JP6483148B2 (ja) 2014-03-14 2019-03-13 エアーピオ セラピューティクス インコーポレイテッド HPTP−β阻害剤
US9539245B2 (en) 2014-08-07 2017-01-10 Aerpio Therapeutics, Inc. Combination of immunotherapies with activators of Tie-2

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853900A (en) 1973-09-14 1974-12-10 Searle & Co 4-benzyloxy-2 (1h)-pyridones
US5358949A (en) * 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
DE4316077A1 (de) * 1993-05-13 1994-11-17 Bayer Ag Substituierte Mono- und Bihydridylmethylpyridone
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5789426A (en) * 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
US6946479B2 (en) * 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones

Also Published As

Publication number Publication date
MA27549A1 (fr) 2005-10-03
CA2502416A1 (en) 2004-05-27
US20050256126A1 (en) 2005-11-17
ATE372986T1 (de) 2007-09-15
KR20070030334A (ko) 2007-03-15
RU2321584C2 (ru) 2008-04-10
NZ539385A (en) 2008-02-29
EP1558580A2 (en) 2005-08-03
HRP20050517B1 (hr) 2014-03-14
CO5570702A2 (es) 2005-10-31
CY1106957T1 (el) 2012-09-26
DK1558580T3 (da) 2008-01-14
US7247632B2 (en) 2007-07-24
EP1558580B1 (en) 2007-09-12
PL377176A1 (pl) 2006-01-23
HRP20050517A2 (en) 2005-12-31
PT1558580E (pt) 2007-12-06
JP4327730B2 (ja) 2009-09-09
RU2005114490A (ru) 2006-01-20
IL168118A (en) 2011-07-31
BR0316086A (pt) 2005-09-27
WO2004043928A2 (en) 2004-05-27
AU2003296045A1 (en) 2004-06-03
NO20052788L (no) 2005-06-09
CA2502416C (en) 2010-07-20
DE60316339D1 (de) 2007-10-25
US20070238722A1 (en) 2007-10-11
AU2003296045B2 (en) 2008-04-03
KR100894237B1 (ko) 2009-04-20
US6946479B2 (en) 2005-09-20
ZA200503682B (en) 2006-11-29
KR20050055793A (ko) 2005-06-13
JP2006513164A (ja) 2006-04-20
DE60316339T2 (de) 2008-06-05
US20040097559A1 (en) 2004-05-20
WO2004043928A8 (en) 2005-05-06
WO2004043928A3 (en) 2004-07-01
CN1708482A (zh) 2005-12-14
MXPA05004897A (es) 2005-11-17
ES2293059T3 (es) 2008-03-16

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