ATE372986T1 - N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridon s als antimikrobielle mittel - Google Patents
N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridon s als antimikrobielle mittelInfo
- Publication number
- ATE372986T1 ATE372986T1 AT03783256T AT03783256T ATE372986T1 AT E372986 T1 ATE372986 T1 AT E372986T1 AT 03783256 T AT03783256 T AT 03783256T AT 03783256 T AT03783256 T AT 03783256T AT E372986 T1 ATE372986 T1 AT E372986T1
- Authority
- AT
- Austria
- Prior art keywords
- methyleneamino
- pyridone
- sulfonyl
- hydroxy
- antimicrobial agent
- Prior art date
Links
- 239000004599 antimicrobial Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42507102P | 2002-11-09 | 2002-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE372986T1 true ATE372986T1 (de) | 2007-09-15 |
Family
ID=32312927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03783256T ATE372986T1 (de) | 2002-11-09 | 2003-11-07 | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridon s als antimikrobielle mittel |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US6946479B2 (de) |
| EP (1) | EP1558580B1 (de) |
| JP (1) | JP4327730B2 (de) |
| KR (2) | KR100894237B1 (de) |
| CN (1) | CN1708482A (de) |
| AT (1) | ATE372986T1 (de) |
| AU (1) | AU2003296045B2 (de) |
| BR (1) | BR0316086A (de) |
| CA (1) | CA2502416C (de) |
| CO (1) | CO5570702A2 (de) |
| CY (1) | CY1106957T1 (de) |
| DE (1) | DE60316339T2 (de) |
| DK (1) | DK1558580T3 (de) |
| ES (1) | ES2293059T3 (de) |
| HR (1) | HRP20050517B1 (de) |
| IL (1) | IL168118A (de) |
| MA (1) | MA27549A1 (de) |
| MX (1) | MXPA05004897A (de) |
| NO (1) | NO331012B1 (de) |
| NZ (1) | NZ539385A (de) |
| PL (1) | PL377176A1 (de) |
| PT (1) | PT1558580E (de) |
| RU (1) | RU2321584C2 (de) |
| WO (1) | WO2004043928A2 (de) |
| ZA (1) | ZA200503682B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946479B2 (en) * | 2002-11-09 | 2005-09-20 | The Procter & Gamble Company | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones |
| US6930117B2 (en) * | 2002-11-09 | 2005-08-16 | The Procter & Gamble Company | N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones |
| US20070275944A1 (en) * | 2006-04-05 | 2007-11-29 | The Board Of Trustees Operating Michigan State University | Antioxidants and methods of their use |
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| MY160399A (en) | 2009-07-06 | 2017-03-15 | Aerpio Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| CN102638983B (zh) | 2009-11-06 | 2014-11-26 | 阿尔皮奥治疗学股份有限公司 | 用于治疗结肠炎的组合物和方法 |
| CN104136026B (zh) | 2011-10-31 | 2018-03-02 | 卫理公会医院研究所 | 包含mao靶向/探寻器部分的人神经胶质瘤治疗用化合物 |
| CN103360308A (zh) * | 2012-03-28 | 2013-10-23 | 孙伟新 | 1,4-二羟基-6-甲基-2-吡啶酮类化合物及其制备方法和用途 |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| GB2516561B (en) | 2013-03-15 | 2016-03-09 | Aerpio Therapeutics Inc | Compositions, formulations and methods for treating ocular diseases |
| JP6549140B2 (ja) | 2014-02-19 | 2019-07-24 | エアーピオ セラピューティクス インコーポレイテッド | Ｎ−ベンジル−３−ヒドロキシ−４−置換ピリジン−２−（１ｈ）−オン |
| CN106456614A (zh) | 2014-03-14 | 2017-02-22 | 爱尔皮奥治疗有限公司 | HPTP‑β抑制剂 |
| US9539245B2 (en) | 2014-08-07 | 2017-01-10 | Aerpio Therapeutics, Inc. | Combination of immunotherapies with activators of Tie-2 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853900A (en) | 1973-09-14 | 1974-12-10 | Searle & Co | 4-benzyloxy-2 (1h)-pyridones |
| US5358949A (en) | 1986-03-05 | 1994-10-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives |
| DE4316077A1 (de) | 1993-05-13 | 1994-11-17 | Bayer Ag | Substituierte Mono- und Bihydridylmethylpyridone |
| US5817825A (en) * | 1994-11-02 | 1998-10-06 | Hoechst Aktiengesellschaft | Process for the preparation of 1-hydroxy-2-pyridones |
| US5789426A (en) | 1995-01-20 | 1998-08-04 | Cornell Research Foundation, Inc. | Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation |
| US6046219A (en) | 1995-01-20 | 2000-04-04 | Cornell Research Foundation, Inc. | Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation |
| US5849587A (en) | 1995-06-09 | 1998-12-15 | Cornell Research Foundation, Inc. | Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells |
| US6946479B2 (en) * | 2002-11-09 | 2005-09-20 | The Procter & Gamble Company | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones |
-
2003
- 2003-11-06 US US10/703,067 patent/US6946479B2/en not_active Expired - Fee Related
- 2003-11-07 RU RU2005114490/04A patent/RU2321584C2/ru not_active IP Right Cessation
- 2003-11-07 HR HRP20050517AA patent/HRP20050517B1/hr not_active IP Right Cessation
- 2003-11-07 EP EP03783256A patent/EP1558580B1/de not_active Expired - Lifetime
- 2003-11-07 CN CNA200380102221XA patent/CN1708482A/zh active Pending
- 2003-11-07 DK DK03783256T patent/DK1558580T3/da active
- 2003-11-07 NZ NZ539385A patent/NZ539385A/en not_active IP Right Cessation
- 2003-11-07 AT AT03783256T patent/ATE372986T1/de active
- 2003-11-07 MX MXPA05004897A patent/MXPA05004897A/es active IP Right Grant
- 2003-11-07 CA CA2502416A patent/CA2502416C/en not_active Expired - Fee Related
- 2003-11-07 WO PCT/US2003/035623 patent/WO2004043928A2/en not_active Ceased
- 2003-11-07 PL PL377176A patent/PL377176A1/pl unknown
- 2003-11-07 KR KR1020077004211A patent/KR100894237B1/ko not_active Expired - Fee Related
- 2003-11-07 AU AU2003296045A patent/AU2003296045B2/en not_active Ceased
- 2003-11-07 JP JP2004551914A patent/JP4327730B2/ja not_active Expired - Fee Related
- 2003-11-07 PT PT03783256T patent/PT1558580E/pt unknown
- 2003-11-07 BR BR0316086-6A patent/BR0316086A/pt not_active IP Right Cessation
- 2003-11-07 KR KR1020057007516A patent/KR20050055793A/ko not_active Ceased
- 2003-11-07 DE DE60316339T patent/DE60316339T2/de not_active Expired - Lifetime
- 2003-11-07 ES ES03783256T patent/ES2293059T3/es not_active Expired - Lifetime
-
2005
- 2005-04-19 IL IL168118A patent/IL168118A/en not_active IP Right Cessation
- 2005-05-09 ZA ZA200503682A patent/ZA200503682B/en unknown
- 2005-05-09 MA MA28270A patent/MA27549A1/fr unknown
- 2005-05-24 CO CO05050160A patent/CO5570702A2/es active IP Right Grant
- 2005-06-09 NO NO20052788A patent/NO331012B1/no not_active IP Right Cessation
- 2005-06-14 US US11/151,897 patent/US7247632B2/en not_active Expired - Fee Related
-
2007
- 2007-06-18 US US11/820,097 patent/US20070238722A1/en not_active Abandoned
- 2007-10-25 CY CY20071101382T patent/CY1106957T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE372985T1 (de) | N-alkyl-4-methylenamino-3-hydroxy-2-pyridone verwendbar als antimikrobielle mittel | |
| DE60131138D1 (de) | Antibakterielle mittel | |
| ECSP003699A (es) | Inhibidores de fab i | |
| CY1106957T1 (el) | Ν-σουλφονυλο-4-μεθυλεναμινο-3-υδροξυ-2-πυριδονες ως αντιμικροβιακοι παραγοντες | |
| ATE464287T1 (de) | Cyclohexyl-sulphone als gamma-sekretase- inhibitoren | |
| NO20051082L (no) | Antimikrobielle kinoloner, deres sammensetninger og anvendelser | |
| ATE368031T1 (de) | Neue gamma secretase inhibitoren | |
| ATE433963T1 (de) | Fab-i inhibitoren | |
| ATE420639T1 (de) | Antimykotische mittel | |
| BG108498A (en) | New derivatives of oxazolidinones as antibacterial agents | |
| PE20030061A1 (es) | 1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4 | |
| ATE516022T1 (de) | Antimikrobielle zusammensetzungen und anwendungsverfahren dafür | |
| SG162614A1 (en) | Bicyclic 6-alkylidene-penems as beta-lactamases inhibitors | |
| NO20062629L (no) | Oksazolderivater av tetrackliner | |
| BR0309878A (pt) | Heterotriciclil-6-alquilideno-penemas como inibidores de beta-lactamase | |
| PT1358182E (pt) | Derivados de diazocinas e sua utilizacao como inibidores de triptase | |
| EA200501830A1 (ru) | Новые производные линкомицина, обладающие антимикробной активностью | |
| FI20020507A0 (fi) | Antimikrobiaine patogeenisia bakteereita vastaan |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1558580 Country of ref document: EP |