DK1558580T3 - N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner - Google Patents

N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner

Info

Publication number
DK1558580T3
DK1558580T3 DK03783256T DK03783256T DK1558580T3 DK 1558580 T3 DK1558580 T3 DK 1558580T3 DK 03783256 T DK03783256 T DK 03783256T DK 03783256 T DK03783256 T DK 03783256T DK 1558580 T3 DK1558580 T3 DK 1558580T3
Authority
DK
Denmark
Prior art keywords
pyridones
methylamino
sulfonyl
hydroxy
compounds
Prior art date
Application number
DK03783256T
Other languages
Danish (da)
English (en)
Inventor
Namal Chithranga Warshakoon
Rodney Dean Bush
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of DK1558580T3 publication Critical patent/DK1558580T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK03783256T 2002-11-09 2003-11-07 N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner DK1558580T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42507102P 2002-11-09 2002-11-09
PCT/US2003/035623 WO2004043928A2 (en) 2002-11-09 2003-11-07 N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobial agents

Publications (1)

Publication Number Publication Date
DK1558580T3 true DK1558580T3 (da) 2008-01-14

Family

ID=32312927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03783256T DK1558580T3 (da) 2002-11-09 2003-11-07 N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner

Country Status (25)

Country Link
US (3) US6946479B2 (ja)
EP (1) EP1558580B1 (ja)
JP (1) JP4327730B2 (ja)
KR (2) KR20050055793A (ja)
CN (1) CN1708482A (ja)
AT (1) ATE372986T1 (ja)
AU (1) AU2003296045B2 (ja)
BR (1) BR0316086A (ja)
CA (1) CA2502416C (ja)
CO (1) CO5570702A2 (ja)
CY (1) CY1106957T1 (ja)
DE (1) DE60316339T2 (ja)
DK (1) DK1558580T3 (ja)
ES (1) ES2293059T3 (ja)
HR (1) HRP20050517B1 (ja)
IL (1) IL168118A (ja)
MA (1) MA27549A1 (ja)
MX (1) MXPA05004897A (ja)
NO (1) NO331012B1 (ja)
NZ (1) NZ539385A (ja)
PL (1) PL377176A1 (ja)
PT (1) PT1558580E (ja)
RU (1) RU2321584C2 (ja)
WO (1) WO2004043928A2 (ja)
ZA (1) ZA200503682B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6930117B2 (en) * 2002-11-09 2005-08-16 The Procter & Gamble Company N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones
US6946479B2 (en) * 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones
US20070275944A1 (en) * 2006-04-05 2007-11-29 The Board Of Trustees Operating Michigan State University Antioxidants and methods of their use
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
JP5536113B2 (ja) 2009-07-06 2014-07-02 アケビア セラピューティクス インコーポレイテッド がん細胞の転移を予防するための化合物、組成物および方法
IN2012DN04950A (ja) * 2009-11-06 2015-09-25 Aerpio Therapeutics Inc
EP2804604A1 (en) 2011-10-31 2014-11-26 The Methodist Hospital Research Institute Compound comprising a mao targeting/ seeker moiety for treating human gliomas
CN103360308A (zh) * 2012-03-28 2013-10-23 孙伟新 1,4-二羟基-6-甲基-2-吡啶酮类化合物及其制备方法和用途
US20150050277A1 (en) 2013-03-15 2015-02-19 Aerpio Therapeutics Inc. Compositions and methods for treating ocular diseases
WO2014145068A1 (en) 2013-03-15 2014-09-18 Aerpio Therapeutics Inc. Compositions, formulations and methods for treating ocular diseases
JP6549140B2 (ja) 2014-02-19 2019-07-24 エアーピオ セラピューティクス インコーポレイテッド N−ベンジル−3−ヒドロキシ−4−置換ピリジン−2−(1h)−オン
JP6483148B2 (ja) 2014-03-14 2019-03-13 エアーピオ セラピューティクス インコーポレイテッド HPTP−β阻害剤
US9539245B2 (en) 2014-08-07 2017-01-10 Aerpio Therapeutics, Inc. Combination of immunotherapies with activators of Tie-2

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853900A (en) 1973-09-14 1974-12-10 Searle & Co 4-benzyloxy-2 (1h)-pyridones
US5358949A (en) 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
DE4316077A1 (de) 1993-05-13 1994-11-17 Bayer Ag Substituierte Mono- und Bihydridylmethylpyridone
US6046219A (en) 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5789426A (en) 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
US5849587A (en) 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
US6946479B2 (en) * 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones

Also Published As

Publication number Publication date
US6946479B2 (en) 2005-09-20
NO331012B1 (no) 2011-09-05
HRP20050517B1 (hr) 2014-03-14
CN1708482A (zh) 2005-12-14
CA2502416A1 (en) 2004-05-27
AU2003296045A1 (en) 2004-06-03
NO20052788L (no) 2005-06-09
US20070238722A1 (en) 2007-10-11
KR20070030334A (ko) 2007-03-15
HRP20050517A2 (en) 2005-12-31
CA2502416C (en) 2010-07-20
JP4327730B2 (ja) 2009-09-09
US20040097559A1 (en) 2004-05-20
ATE372986T1 (de) 2007-09-15
BR0316086A (pt) 2005-09-27
EP1558580B1 (en) 2007-09-12
RU2321584C2 (ru) 2008-04-10
WO2004043928A3 (en) 2004-07-01
DE60316339D1 (de) 2007-10-25
WO2004043928A2 (en) 2004-05-27
AU2003296045B2 (en) 2008-04-03
CY1106957T1 (el) 2012-09-26
DE60316339T2 (de) 2008-06-05
EP1558580A2 (en) 2005-08-03
IL168118A (en) 2011-07-31
MA27549A1 (fr) 2005-10-03
PT1558580E (pt) 2007-12-06
JP2006513164A (ja) 2006-04-20
CO5570702A2 (es) 2005-10-31
ES2293059T3 (es) 2008-03-16
ZA200503682B (en) 2006-11-29
US20050256126A1 (en) 2005-11-17
RU2005114490A (ru) 2006-01-20
KR20050055793A (ko) 2005-06-13
US7247632B2 (en) 2007-07-24
KR100894237B1 (ko) 2009-04-20
WO2004043928A8 (en) 2005-05-06
PL377176A1 (pl) 2006-01-23
NZ539385A (en) 2008-02-29
MXPA05004897A (es) 2005-11-17

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