NO326899B1 - Antibakterielt protein samt anvendelser derav, terapeutisk formulering, polynukleotid og isolert organisme. - Google Patents
Antibakterielt protein samt anvendelser derav, terapeutisk formulering, polynukleotid og isolert organisme. Download PDFInfo
- Publication number
- NO326899B1 NO326899B1 NO20013905A NO20013905A NO326899B1 NO 326899 B1 NO326899 B1 NO 326899B1 NO 20013905 A NO20013905 A NO 20013905A NO 20013905 A NO20013905 A NO 20013905A NO 326899 B1 NO326899 B1 NO 326899B1
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- Norway
- Prior art keywords
- therapeutic formulation
- organism
- protein
- salivaricin
- formulation according
- Prior art date
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- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
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- 229960003276 erythromycin Drugs 0.000 description 1
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- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
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- 239000002054 inoculum Substances 0.000 description 1
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- 238000001038 ionspray mass spectrometry Methods 0.000 description 1
- 238000010829 isocratic elution Methods 0.000 description 1
- 229960000310 isoleucine Drugs 0.000 description 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 108010087689 lacticin 481 Proteins 0.000 description 1
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- 230000002934 lysing effect Effects 0.000 description 1
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- 238000002156 mixing Methods 0.000 description 1
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- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 239000013605 shuttle vector Substances 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 235000020183 skimmed milk Nutrition 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000016765 streptococcal sore throat Diseases 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 108010005406 variacin Proteins 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Jellies, Jams, And Syrups (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Confectionery (AREA)
- Dairy Products (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ50026199 | 1999-10-12 | ||
| PCT/NZ2000/000197 WO2001027143A1 (fr) | 1999-10-12 | 2000-10-12 | Lantibiotique |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20013905D0 NO20013905D0 (no) | 2001-08-10 |
| NO20013905L NO20013905L (no) | 2001-10-10 |
| NO326899B1 true NO326899B1 (no) | 2009-03-16 |
Family
ID=19927569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20013905A NO326899B1 (no) | 1999-10-12 | 2001-08-10 | Antibakterielt protein samt anvendelser derav, terapeutisk formulering, polynukleotid og isolert organisme. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6773912B1 (fr) |
| EP (1) | EP1169340B1 (fr) |
| JP (1) | JP3673497B2 (fr) |
| AT (1) | ATE362481T1 (fr) |
| AU (1) | AU772224B2 (fr) |
| BR (1) | BR0014740A (fr) |
| CA (1) | CA2363713C (fr) |
| DE (1) | DE60034879T8 (fr) |
| DK (1) | DK1169340T3 (fr) |
| ES (1) | ES2286038T3 (fr) |
| HK (1) | HK1039622B (fr) |
| NO (1) | NO326899B1 (fr) |
| PL (1) | PL206441B1 (fr) |
| RU (1) | RU2279481C2 (fr) |
| WO (1) | WO2001027143A1 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1483366B1 (fr) * | 2002-02-22 | 2010-04-14 | Blis Technologies Limited | Composition antimicrobienne |
| US6861236B2 (en) | 2002-05-24 | 2005-03-01 | Applied Nanosystems B.V. | Export and modification of (poly)peptides in the lantibiotic way |
| WO2004072272A1 (fr) * | 2003-02-14 | 2004-08-26 | Blis Technologies Limited | Compositions bactériennes |
| DK1653982T3 (en) * | 2003-07-18 | 2019-01-14 | Blis Tech Limited | TREATMENT OF HALITOSIS |
| CA2557333A1 (fr) * | 2004-02-24 | 2005-09-01 | Commonwealth Scientific And Industrial Research Organisation | Peptides antifongiques |
| US8415289B2 (en) * | 2005-12-13 | 2013-04-09 | The Trustees Of The University Of Pennsylvania | Bacterial-derived BLIS for treatment of acne |
| FR2905268B1 (fr) * | 2006-09-01 | 2009-01-23 | Unither Dev Soc Par Actions Si | Substitut salivaire |
| RU2446208C9 (ru) * | 2006-12-19 | 2012-11-10 | Басф Се | Применение и способ профилактики или лечения кариеса, вызванного mutans streptococci, отличных от streptococcus mutans |
| GB0921995D0 (en) * | 2009-12-17 | 2010-02-03 | Univ Manchester | Antimicrobial peptides |
| SI2555785T1 (sl) * | 2010-04-07 | 2016-07-29 | D.M.G. Italia Srl | Uporaba Streptococcusa salivariusa pri zdravljenju kroničnih infekcij respiratornega trakta |
| DE102012203547A1 (de) * | 2012-03-07 | 2013-09-12 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Antimikrobielle Peptide |
| CA2783414A1 (fr) * | 2012-07-22 | 2014-01-22 | Integral Medical Inc. | Composition probiotique |
| CN104398537A (zh) * | 2014-11-17 | 2015-03-11 | 南京灿辰微生物科技有限公司 | 一种口腔益生菌组合物 |
| CN111227035A (zh) * | 2018-11-28 | 2020-06-05 | 内蒙古伊利实业集团股份有限公司 | 一种含益生菌组合物的发酵乳及其制备方法 |
| CN112391305B (zh) * | 2019-08-15 | 2023-01-13 | 上海交通大学 | 唾液链球菌f286及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3925160A (en) | 1974-09-26 | 1975-12-09 | Univ Creighton | Method of producing an antibiotic |
| JPS615022A (ja) * | 1984-06-19 | 1986-01-10 | Advance Res & Dev Co Ltd | 腸内細菌叢改善剤 |
| SE463349B (sv) | 1989-02-15 | 1990-11-12 | Grahn Eva E | Farmaceutiskt preparat foer profylax mot och/eller behandling av beta-streptokockinducerad tonsillit |
| JPH054927A (ja) * | 1991-06-28 | 1993-01-14 | Aizo Matsushiro | 乳酸菌含有組成物及びその製造方法 |
| US5872001A (en) | 1994-04-20 | 1999-02-16 | Uab Research Foundation | Lanthionine antibiotic compositions and methods |
-
2000
- 2000-10-12 RU RU2002112327/13A patent/RU2279481C2/ru active
- 2000-10-12 EP EP00970338A patent/EP1169340B1/fr not_active Expired - Lifetime
- 2000-10-12 BR BR0014740-0A patent/BR0014740A/pt not_active Application Discontinuation
- 2000-10-12 US US09/913,763 patent/US6773912B1/en not_active Expired - Lifetime
- 2000-10-12 PL PL364771A patent/PL206441B1/pl unknown
- 2000-10-12 JP JP2001530361A patent/JP3673497B2/ja not_active Expired - Fee Related
- 2000-10-12 ES ES00970338T patent/ES2286038T3/es not_active Expired - Lifetime
- 2000-10-12 DK DK00970338T patent/DK1169340T3/da active
- 2000-10-12 DE DE60034879T patent/DE60034879T8/de active Active
- 2000-10-12 CA CA002363713A patent/CA2363713C/fr not_active Expired - Lifetime
- 2000-10-12 AT AT00970338T patent/ATE362481T1/de not_active IP Right Cessation
- 2000-10-12 AU AU79737/00A patent/AU772224B2/en not_active Expired
- 2000-10-12 WO PCT/NZ2000/000197 patent/WO2001027143A1/fr active IP Right Grant
-
2001
- 2001-08-10 NO NO20013905A patent/NO326899B1/no not_active IP Right Cessation
-
2002
- 2002-02-07 HK HK02100947.2A patent/HK1039622B/zh unknown
-
2004
- 2004-05-19 US US10/848,750 patent/US20040232205A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU772224B2 (en) | 2004-04-22 |
| RU2279481C2 (ru) | 2006-07-10 |
| CA2363713A1 (fr) | 2001-04-19 |
| WO2001027143A1 (fr) | 2001-04-19 |
| PL364771A1 (en) | 2004-12-13 |
| EP1169340B1 (fr) | 2007-05-16 |
| AU7973700A (en) | 2001-04-23 |
| HK1039622A1 (en) | 2002-05-03 |
| US20040232205A1 (en) | 2004-11-25 |
| DE60034879D1 (en) | 2007-06-28 |
| NO20013905L (no) | 2001-10-10 |
| CA2363713C (fr) | 2007-11-06 |
| ATE362481T1 (de) | 2007-06-15 |
| DK1169340T3 (da) | 2007-09-24 |
| EP1169340A4 (fr) | 2005-06-08 |
| JP2003516123A (ja) | 2003-05-13 |
| NO20013905D0 (no) | 2001-08-10 |
| DE60034879T2 (de) | 2008-02-07 |
| JP3673497B2 (ja) | 2005-07-20 |
| EP1169340A1 (fr) | 2002-01-09 |
| PL206441B1 (pl) | 2010-08-31 |
| HK1039622B (zh) | 2007-10-18 |
| US6773912B1 (en) | 2004-08-10 |
| DE60034879T8 (de) | 2008-07-03 |
| ES2286038T3 (es) | 2007-12-01 |
| BR0014740A (pt) | 2002-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |