NO325879B1 - Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor. - Google Patents

Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor. Download PDF

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Publication number
NO325879B1
NO325879B1 NO19975286A NO975286A NO325879B1 NO 325879 B1 NO325879 B1 NO 325879B1 NO 19975286 A NO19975286 A NO 19975286A NO 975286 A NO975286 A NO 975286A NO 325879 B1 NO325879 B1 NO 325879B1
Authority
NO
Norway
Prior art keywords
protein
recombinant dna
promoter
expression
region
Prior art date
Application number
NO19975286A
Other languages
English (en)
Norwegian (no)
Other versions
NO975286D0 (no
NO975286L (no
Inventor
Peter A Lagosky
Original Assignee
Allelix Biopharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allelix Biopharma filed Critical Allelix Biopharma
Publication of NO975286D0 publication Critical patent/NO975286D0/no
Publication of NO975286L publication Critical patent/NO975286L/no
Publication of NO325879B1 publication Critical patent/NO325879B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19975286A 1995-05-19 1997-11-18 Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor. NO325879B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/445,133 US5629205A (en) 1995-05-19 1995-05-19 Promoters for gene expression
PCT/IB1996/000462 WO1996036721A1 (en) 1995-05-19 1996-05-16 Promoters for gene expression

Publications (3)

Publication Number Publication Date
NO975286D0 NO975286D0 (no) 1997-11-18
NO975286L NO975286L (no) 1997-11-18
NO325879B1 true NO325879B1 (no) 2008-08-11

Family

ID=23767732

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975286A NO325879B1 (no) 1995-05-19 1997-11-18 Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor.

Country Status (24)

Country Link
US (1) US5629205A (cs)
EP (1) EP0828844B1 (cs)
JP (2) JP3828576B2 (cs)
KR (1) KR19990014906A (cs)
CN (1) CN1131313C (cs)
AT (1) ATE248923T1 (cs)
AU (1) AU698656B2 (cs)
BR (1) BR9609102A (cs)
CA (1) CA2221587C (cs)
CZ (1) CZ357997A3 (cs)
DE (1) DE69629808T2 (cs)
DK (1) DK0828844T3 (cs)
EE (1) EE9700355A (cs)
ES (1) ES2202436T3 (cs)
HU (1) HUP9900750A3 (cs)
IS (1) IS4609A (cs)
MX (1) MX9708689A (cs)
NO (1) NO325879B1 (cs)
NZ (1) NZ306536A (cs)
PL (1) PL324226A1 (cs)
PT (1) PT828844E (cs)
SK (1) SK154997A3 (cs)
TR (1) TR199701394T1 (cs)
WO (1) WO1996036721A1 (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194168B1 (en) 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
CA2485703A1 (en) * 2002-05-24 2003-12-04 Fred W. Wagner Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
US20050119183A1 (en) * 2003-11-12 2005-06-02 Nps Allelix Corp. Method for treating bone loss using parathyroid hormone
EP1704234B1 (en) 2003-11-21 2012-01-18 NPS Pharmaceuticals, Inc. Production of glucagon like peptide 2 and analogs
US20060177895A1 (en) * 2003-12-12 2006-08-10 Chung Chan Methods for enhancing expression of recombinant proteins
CA2865033C (en) 2012-02-23 2021-11-02 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
RU2021134624A (ru) 2015-10-22 2022-03-15 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции
EP4647493A2 (en) 2017-04-27 2025-11-12 Juno Therapeutics, Inc. Oligomeric particle reagents and methods of use thereof
CN108060168B (zh) * 2017-12-29 2021-06-29 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的t载体和应用
CN108118059B (zh) * 2017-12-30 2021-03-19 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的载体和应用
CN108165551B (zh) * 2017-12-30 2021-06-29 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的t载体和应用
WO2020053285A1 (en) * 2018-09-11 2020-03-19 Boehringer Ingelheim Rcv Gmbh & Co Kg Inducible expression system for plasmid-free production of a protein of interest
CN118995554B (zh) * 2024-09-09 2025-07-04 江南大学 一种大肠杆菌整合表达体系及其在酶高效表达中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8517071D0 (en) * 1985-07-05 1985-08-14 Hoffmann La Roche Gram-positive expression control sequence
DK443288A (da) * 1987-08-17 1989-02-18 Hoffmann La Roche Ekspressionskontrolsekvenser
US5223407A (en) * 1988-08-31 1993-06-29 Allelix Inc. Excretion of heterologous proteins from e. coli
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
CA2067249A1 (en) * 1990-08-28 1992-03-01 Vasantha Nagarajan Method for rapid selection of efficient secretion vectors

Also Published As

Publication number Publication date
TR199701394T1 (xx) 1998-02-21
HUP9900750A3 (en) 1999-11-29
AU5511696A (en) 1996-11-29
IS4609A (is) 1997-11-07
JP3828576B2 (ja) 2006-10-04
CZ357997A3 (cs) 1998-04-15
MX9708689A (es) 1998-02-28
JPH11509083A (ja) 1999-08-17
DK0828844T3 (da) 2004-01-05
HUP9900750A2 (hu) 1999-06-28
JP3837154B2 (ja) 2006-10-25
ATE248923T1 (de) 2003-09-15
BR9609102A (pt) 1999-05-11
PL324226A1 (en) 1998-05-11
AU698656B2 (en) 1998-11-05
NO975286D0 (no) 1997-11-18
CA2221587A1 (en) 1996-11-21
SK154997A3 (en) 1998-05-06
US5629205A (en) 1997-05-13
DE69629808D1 (de) 2003-10-09
WO1996036721A1 (en) 1996-11-21
JP2006187295A (ja) 2006-07-20
NO975286L (no) 1997-11-18
EP0828844B1 (en) 2003-09-03
EP0828844A1 (en) 1998-03-18
CA2221587C (en) 2008-07-08
ES2202436T3 (es) 2004-04-01
EE9700355A (et) 1998-06-15
DE69629808T2 (de) 2004-07-15
CN1131313C (zh) 2003-12-17
PT828844E (pt) 2004-01-30
HK1004148A1 (en) 1998-11-20
NZ306536A (en) 1999-10-28
CN1190993A (zh) 1998-08-19
KR19990014906A (ko) 1999-02-25

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