NO324828B1 - Kapillaroppstilling og apparat for utforelse av fotometrisk analyse og anvendelse derav. - Google Patents
Kapillaroppstilling og apparat for utforelse av fotometrisk analyse og anvendelse derav. Download PDFInfo
- Publication number
- NO324828B1 NO324828B1 NO20001389A NO20001389A NO324828B1 NO 324828 B1 NO324828 B1 NO 324828B1 NO 20001389 A NO20001389 A NO 20001389A NO 20001389 A NO20001389 A NO 20001389A NO 324828 B1 NO324828 B1 NO 324828B1
- Authority
- NO
- Norway
- Prior art keywords
- capillary
- capillaries
- light
- liquid
- fluorescence
- Prior art date
Links
- 238000005375 photometry Methods 0.000 title claims description 7
- 230000003287 optical effect Effects 0.000 claims abstract description 14
- 238000002955 isolation Methods 0.000 claims abstract description 7
- 230000004044 response Effects 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims description 34
- 239000000463 material Substances 0.000 claims description 23
- 238000004458 analytical method Methods 0.000 claims description 22
- 239000000758 substrate Substances 0.000 claims description 19
- 239000004033 plastic Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
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- 238000004020 luminiscence type Methods 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
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- 230000005284 excitation Effects 0.000 description 9
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 9
- 239000011248 coating agent Substances 0.000 description 8
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000005119 centrifugation Methods 0.000 description 4
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- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
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- 239000005350 fused silica glass Substances 0.000 description 2
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- 238000000862 absorption spectrum Methods 0.000 description 1
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- 239000004411 aluminium Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000013522 chelant Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
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- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
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- 238000009736 wetting Methods 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
- B01L9/065—Test-tube stands; Test-tube holders specially adapted for capillary tubes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Polarising Elements (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9719673.7A GB9719673D0 (en) | 1997-09-17 | 1997-09-17 | Novel apparatus |
| PCT/EP1998/005838 WO1999013986A1 (en) | 1997-09-17 | 1998-09-15 | Apparatus for performing photometric assays |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20001389D0 NO20001389D0 (no) | 2000-03-16 |
| NO20001389L NO20001389L (no) | 2000-05-10 |
| NO324828B1 true NO324828B1 (no) | 2007-12-10 |
Family
ID=10819146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001389A NO324828B1 (no) | 1997-09-17 | 2000-03-16 | Kapillaroppstilling og apparat for utforelse av fotometrisk analyse og anvendelse derav. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6652809B1 (de) |
| EP (1) | EP1015111B1 (de) |
| JP (1) | JP2001516870A (de) |
| AT (1) | ATE221802T1 (de) |
| AU (1) | AU747973B2 (de) |
| CA (1) | CA2304059C (de) |
| DE (1) | DE69807089T2 (de) |
| ES (1) | ES2180203T3 (de) |
| GB (1) | GB9719673D0 (de) |
| NO (1) | NO324828B1 (de) |
| NZ (1) | NZ503388A (de) |
| WO (1) | WO1999013986A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6580700A (en) * | 1999-08-13 | 2001-03-13 | Cartesian Technologies, Inc. | Apparatus for liquid sample handling |
| GB2368640B (en) * | 1999-08-13 | 2003-09-17 | Cartesian Technologies Inc | Apparatus for liquid sample handling |
| US20070020662A1 (en) * | 2000-01-07 | 2007-01-25 | Transform Pharmaceuticals, Inc. | Computerized control of high-throughput experimental processing and digital analysis of comparative samples for a compound of interest |
| US20070021929A1 (en) * | 2000-01-07 | 2007-01-25 | Transform Pharmaceuticals, Inc. | Computing methods for control of high-throughput experimental processing, digital analysis, and re-arraying comparative samples in computer-designed arrays |
| US6870613B1 (en) * | 2001-03-07 | 2005-03-22 | Carolyn Tisone | Simultaneous recording of multispectral fluorescence signatures |
| JP2002277356A (ja) * | 2001-03-21 | 2002-09-25 | Sumitomo Chem Co Ltd | ガラスキャピラリーへの試料導入方法および示差走査熱量計用測定試料の調製方法 |
| US20030106492A1 (en) * | 2001-09-07 | 2003-06-12 | Douglas Levinson | Apparatus and method for high-throughput preparation, visualization and screening of compositions |
| JP4146648B2 (ja) * | 2002-02-14 | 2008-09-10 | 三菱電機株式会社 | 吸収線量分布測定装置 |
| CA2419199A1 (en) * | 2002-03-05 | 2003-09-05 | Bayer Healthcare, Llc | Minimum invasive optical format with integrated lance |
| JP4611750B2 (ja) * | 2002-12-20 | 2011-01-12 | コーニング インコーポレイテッド | キャピラリー・アッセイ・デバイスおよび方法 |
| WO2004078352A2 (en) * | 2003-03-05 | 2004-09-16 | Amersham Biosciences (Sv) Corp | Microtiter plate for holding small volumes of liquids |
| US20090052850A1 (en) * | 2003-09-05 | 2009-02-26 | Loic Barbedette | Micro-well plates and methods of fabricating and selectively blackening the same |
| CN1917810A (zh) * | 2004-02-06 | 2007-02-21 | 拜尔健康护理有限责任公司 | 用于对在体液内的分析物进行测量的方法和设备 |
| US7315376B2 (en) * | 2005-01-07 | 2008-01-01 | Advanced Molecular Systems, Llc | Fluorescence detection system |
| JP2009510475A (ja) * | 2005-10-03 | 2009-03-12 | クリアティーヴィ・マイクロテク，インコーポレーテッド | 感応式放出光収集及び検出システム |
| US8351741B2 (en) * | 2005-10-03 | 2013-01-08 | Creatv Microtech, Inc. | Sensitive emission light gathering and flow through detection system |
| WO2007057468A1 (en) * | 2005-11-21 | 2007-05-24 | Boehringer Ingelheim International Gmbh | Method and complete system for developing formulations and the in vitro testing thereof with good predictability of the absorption in vivo, high throughput and low requirement of active substance |
| ITMI20061063A1 (it) * | 2006-05-31 | 2007-12-01 | Mindseeds Lab S R L | Metrodo e apparato pe rla selezione e la modifica di singole cellule e loro piccoli aggregati |
| JP5208107B2 (ja) * | 2007-04-20 | 2013-06-12 | 和光純薬工業株式会社 | 微量検体測定用硝子セルバイアル |
| EP3181228B1 (de) * | 2007-10-02 | 2020-07-29 | Labrador Diagnostics LLC | Modulare poc-vorrichtungen und ihre verwendung |
| US9816131B2 (en) | 2010-08-02 | 2017-11-14 | Dxna Llc | Pressurizable cartridge for polymerase chain reactions |
| EP2646830B1 (de) | 2010-12-03 | 2016-04-13 | Cellply S.R.L. | Schneller screening von monoklonalantikörpern |
| KR20130086743A (ko) * | 2012-01-26 | 2013-08-05 | 삼성전자주식회사 | 미세유동장치 및 그 제어방법 |
| WO2013136891A1 (ja) * | 2012-03-12 | 2013-09-19 | オリンパス株式会社 | 光分析装置、光分析用レンズおよび光分析用容器 |
| US10422806B1 (en) | 2013-07-25 | 2019-09-24 | Theranos Ip Company, Llc | Methods for improving assays of biological samples |
| US20150048003A1 (en) * | 2013-08-16 | 2015-02-19 | Xiaomin CAI | Capillary Storage System |
| US10863736B2 (en) * | 2013-11-20 | 2020-12-15 | Xiaomin CAI | Aliquoting and freezing storage device |
| WO2016073832A1 (en) | 2014-11-07 | 2016-05-12 | Theranos, Inc. | Improved methods, devices, and systems for mixing fluids |
| CA3027317A1 (en) | 2016-06-14 | 2017-12-21 | Cellply S.R.L. | Screening kit and method |
| JP6803499B2 (ja) * | 2016-09-06 | 2020-12-23 | 国立大学法人九州大学 | 光学測定システム及び光学セル |
| JP6924452B2 (ja) * | 2016-09-06 | 2021-08-25 | 国立大学法人九州大学 | 光学測定システム及び光学セル |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8501998A1 (es) * | 1982-10-12 | 1984-12-16 | Dynatech Lab | Un recipiente que tiene al menos una cavidad o pocillo para contener al menos una muestra de ensayo durante una medicion fluometrica. |
| US5202010A (en) | 1987-11-25 | 1993-04-13 | Princeton Biochemicals, Inc. | Automated capillary electrophoresis apparatus |
| JPH01105849U (de) * | 1988-01-07 | 1989-07-17 | ||
| DE9002496U1 (de) * | 1989-07-11 | 1990-05-03 | Laboratorium Prof. Dr. Rudolf Berthold, 7547 Wildbad | Probenrack mit einsetzbaren Küvetten |
| US5048957A (en) * | 1989-07-11 | 1991-09-17 | Fritz Berthold | Speciman rack with insertable cuvettes |
| US5274240A (en) | 1990-01-12 | 1993-12-28 | The Regents Of The University Of California | Capillary array confocal fluorescence scanner and method |
| DE4030699C1 (de) * | 1990-09-28 | 1991-10-10 | Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De | |
| US5516409A (en) | 1991-02-28 | 1996-05-14 | Hitachi, Ltd. | DNA detector and DNA detection method |
| JP2785530B2 (ja) * | 1991-09-13 | 1998-08-13 | 株式会社日立製作所 | 電気泳動装置 |
| JP3332969B2 (ja) * | 1991-12-26 | 2002-10-07 | オリンパス光学工業株式会社 | 化学発光分析装置 |
| US5413686A (en) | 1992-07-17 | 1995-05-09 | Beckman Instruments, Inc. | Multi-channel automated capillary electrophoresis analyzer |
| CA2094343A1 (en) | 1992-07-17 | 1994-01-18 | Gerald L. Klein | Method and apparatus for displaying capillary electrophoresis data |
| JPH0655084A (ja) * | 1992-08-06 | 1994-03-01 | Olympus Optical Co Ltd | 免疫測定用反応容器 |
| JPH06102182A (ja) * | 1992-09-18 | 1994-04-15 | Toyobo Co Ltd | 発光法による核酸測定用プレート |
| US5324401A (en) | 1993-02-05 | 1994-06-28 | Iowa State University Research Foundation, Inc. | Multiplexed fluorescence detector system for capillary electrophoresis |
| JP3230890B2 (ja) | 1993-04-07 | 2001-11-19 | 株式会社日立製作所 | 電気泳動分離分析装置 |
| US5417925A (en) | 1993-04-16 | 1995-05-23 | Beckman Instruments, Inc. | Capillary and capillary retaining system |
| JP3563140B2 (ja) | 1995-01-19 | 2004-09-08 | 株式会社日立製作所 | キャピラリーアレイ電気泳動装置 |
| US5439578A (en) | 1993-06-03 | 1995-08-08 | The Governors Of The University Of Alberta | Multiple capillary biochemical analyzer |
| JPH0720037A (ja) * | 1993-07-01 | 1995-01-24 | J T Sci:Kk | タイタプレート |
| GB9321650D0 (en) | 1993-10-20 | 1993-12-08 | Genome Research Limited | Improvements in or relating to electrophoresis |
| EP0724717B1 (de) * | 1993-10-21 | 1998-08-19 | Abbott Laboratories | Vorrichtung und verfahren zur überführung einer probe eines fluids |
| JP3340544B2 (ja) | 1993-12-24 | 2002-11-05 | 株式会社日立製作所 | 分別採取装置及び分別採取方法 |
| CA2182513A1 (en) * | 1994-02-01 | 1995-08-10 | Robert E. Fields | Molecular analyzer and method of use |
| US5840573A (en) * | 1994-02-01 | 1998-11-24 | Fields; Robert E. | Molecular analyzer and method of use |
| US5976896A (en) * | 1994-06-06 | 1999-11-02 | Idexx Laboratories, Inc. | Immunoassays in capillary tubes |
| US5483075A (en) | 1994-11-01 | 1996-01-09 | Perkin-Elmer Corporation | Rotary scanning apparatus |
| US5560811A (en) | 1995-03-21 | 1996-10-01 | Seurat Analytical Systems Incorporated | Capillary electrophoresis apparatus and method |
| US5567294A (en) * | 1996-01-30 | 1996-10-22 | Board Of Governors, University Of Alberta | Multiple capillary biochemical analyzer with barrier member |
| US5858194A (en) * | 1996-07-18 | 1999-01-12 | Beckman Instruments, Inc. | Capillary, interface and holder |
| WO1998008092A1 (en) * | 1996-08-21 | 1998-02-26 | Smithkline Beecham Corporation | Rapid process for arraying and synthesizing bead-based combinatorial libraries |
| US6063251A (en) * | 1997-05-30 | 2000-05-16 | Spectrumedix Corporation | Electrically insulated capillary arrays for electrophoretic applications |
| US5776078A (en) * | 1996-11-25 | 1998-07-07 | Robert A. Levine | Cassette holder for capillary tube blood testing with integral sealing means |
| US6027695A (en) * | 1998-04-01 | 2000-02-22 | Dupont Pharmaceuticals Company | Apparatus for holding small volumes of liquids |
| CA2367912A1 (en) * | 1999-03-19 | 2000-09-28 | Genencor International, Inc. | Multi-through hole testing plate for high throughput screening |
-
1997
- 1997-09-17 GB GBGB9719673.7A patent/GB9719673D0/en not_active Ceased
-
1998
- 1998-09-15 DE DE69807089T patent/DE69807089T2/de not_active Expired - Fee Related
- 1998-09-15 US US09/508,834 patent/US6652809B1/en not_active Expired - Fee Related
- 1998-09-15 AT AT98948972T patent/ATE221802T1/de not_active IP Right Cessation
- 1998-09-15 CA CA002304059A patent/CA2304059C/en not_active Expired - Fee Related
- 1998-09-15 NZ NZ503388A patent/NZ503388A/xx unknown
- 1998-09-15 JP JP2000511589A patent/JP2001516870A/ja active Pending
- 1998-09-15 ES ES98948972T patent/ES2180203T3/es not_active Expired - Lifetime
- 1998-09-15 AU AU95401/98A patent/AU747973B2/en not_active Ceased
- 1998-09-15 EP EP98948972A patent/EP1015111B1/de not_active Expired - Lifetime
- 1998-09-15 WO PCT/EP1998/005838 patent/WO1999013986A1/en active IP Right Grant
-
2000
- 2000-03-16 NO NO20001389A patent/NO324828B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999013986A1 (en) | 1999-03-25 |
| GB9719673D0 (en) | 1997-11-19 |
| JP2001516870A (ja) | 2001-10-02 |
| ATE221802T1 (de) | 2002-08-15 |
| DE69807089T2 (de) | 2003-03-20 |
| NO20001389D0 (no) | 2000-03-16 |
| CA2304059C (en) | 2007-03-27 |
| AU747973B2 (en) | 2002-05-30 |
| US6652809B1 (en) | 2003-11-25 |
| NO20001389L (no) | 2000-05-10 |
| EP1015111A1 (de) | 2000-07-05 |
| DE69807089D1 (de) | 2002-09-12 |
| EP1015111B1 (de) | 2002-08-07 |
| CA2304059A1 (en) | 1999-03-25 |
| ES2180203T3 (es) | 2003-02-01 |
| AU9540198A (en) | 1999-04-05 |
| NZ503388A (en) | 2002-09-27 |
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