NO323778B1 - Piperazin- og piperidinforbindelser, farmasoytisk preparat inneholdende disse samt fremgangsmate for fremstilling og anvendelse av nevnte forbindelser - Google Patents

Piperazin- og piperidinforbindelser, farmasoytisk preparat inneholdende disse samt fremgangsmate for fremstilling og anvendelse av nevnte forbindelser Download PDF

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Publication number
NO323778B1
NO323778B1 NO20025365A NO20025365A NO323778B1 NO 323778 B1 NO323778 B1 NO 323778B1 NO 20025365 A NO20025365 A NO 20025365A NO 20025365 A NO20025365 A NO 20025365A NO 323778 B1 NO323778 B1 NO 323778B1
Authority
NO
Norway
Prior art keywords
compounds
hydrogen
compound according
formula
preparation
Prior art date
Application number
NO20025365A
Other languages
English (en)
Norwegian (no)
Other versions
NO20025365L (no
NO20025365D0 (no
Inventor
Gustaaf Johan Mar Scharrenburg
Roelof W Feenstra
Stephen K Long
Cornelis Gerrit Kruse
Johannes A M Van Der Heijden
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of NO20025365L publication Critical patent/NO20025365L/no
Publication of NO20025365D0 publication Critical patent/NO20025365D0/no
Publication of NO323778B1 publication Critical patent/NO323778B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
NO20025365A 2000-05-12 2002-11-08 Piperazin- og piperidinforbindelser, farmasoytisk preparat inneholdende disse samt fremgangsmate for fremstilling og anvendelse av nevnte forbindelser NO323778B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00201699 2000-05-12
PCT/EP2001/005320 WO2001085725A1 (en) 2000-05-12 2001-05-10 Piperazine and piperidine compounds

Publications (3)

Publication Number Publication Date
NO20025365L NO20025365L (no) 2002-11-08
NO20025365D0 NO20025365D0 (no) 2002-11-08
NO323778B1 true NO323778B1 (no) 2007-07-02

Family

ID=8171488

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025365A NO323778B1 (no) 2000-05-12 2002-11-08 Piperazin- og piperidinforbindelser, farmasoytisk preparat inneholdende disse samt fremgangsmate for fremstilling og anvendelse av nevnte forbindelser

Country Status (27)

Country Link
US (2) US6911448B2 (cs)
EP (1) EP1283838B1 (cs)
JP (1) JP2003532729A (cs)
CN (1) CN1174979C (cs)
AR (1) AR028443A1 (cs)
AT (1) ATE255578T1 (cs)
AU (2) AU6392701A (cs)
BR (1) BR0110592A (cs)
CA (1) CA2405971C (cs)
CZ (1) CZ301464B6 (cs)
DE (1) DE60101386T2 (cs)
DK (1) DK1283838T3 (cs)
DZ (1) DZ3370A1 (cs)
ES (1) ES2211809T3 (cs)
HU (1) HUP0302016A2 (cs)
IL (2) IL152177A0 (cs)
MX (1) MXPA02011084A (cs)
NO (1) NO323778B1 (cs)
NZ (1) NZ522116A (cs)
PL (1) PL198857B1 (cs)
PT (1) PT1283838E (cs)
RU (1) RU2261250C2 (cs)
SK (1) SK286778B6 (cs)
TR (1) TR200302294T4 (cs)
UA (1) UA72337C2 (cs)
WO (1) WO2001085725A1 (cs)
ZA (1) ZA200208537B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1283838E (pt) * 2000-05-12 2004-04-30 Solvay Pharm Bv Compostos de piperazina e de piperidina
WO2003007956A1 (en) 2001-07-20 2003-01-30 Psychogenics, Inc. Treatment for attention-deficit hyperactivity disorder
WO2004000837A1 (ja) * 2002-06-25 2003-12-31 Sumitomo Pharmaceuticals Co., Ltd. 新規なベンズオキサゾリノン誘導体
ES2232292B1 (es) * 2003-07-30 2006-11-01 Laboratorios Del Dr. Esteve, S.A. Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos.
EP1595542A1 (en) * 2004-03-26 2005-11-16 Solvay Pharmaceuticals B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
US7596407B2 (en) 2004-03-26 2009-09-29 Solvay Pharmaceuticals, B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
US7750013B2 (en) 2005-08-22 2010-07-06 Solvay Pharmaceuticals, B.V. N-oxides as prodrugs of piperazine and piperidine derivatives
CA2621158A1 (en) * 2005-08-22 2007-03-01 Solvay Pharmaceuticals B.V. N-oxides as prodrugs of piperazine & piperidine derivatives
AR058022A1 (es) * 2005-08-22 2008-01-23 Solvay Pharm Bv Derivados de benzooxazoles, composiciones farmaceuticas y su uso para el tratamiento de desordenes del sistema nervioso.
US20070275977A1 (en) * 2006-05-02 2007-11-29 Van Aar Marcel P N-oxides of pyridylmethyl -piperazine and -piperidine derivatives
US8106056B2 (en) 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
WO2008068159A1 (en) 2006-12-07 2008-06-12 F. Hoffmann-La Roche Ag Spiro-piperidine derivatives
ES2344131T3 (es) 2006-12-07 2010-08-18 F. Hoffmann-La Roche Ag Derivados de espiro-piperidina como antagonistas del receptor v1a.
ATE472544T1 (de) 2006-12-08 2010-07-15 Hoffmann La Roche Als via-rezeptor-antagonisten verwendbare indole
AU2007328993B2 (en) 2006-12-08 2012-05-10 F. Hoffmann-La Roche Ag Indoles
KR20090082502A (ko) 2006-12-22 2009-07-30 에프. 호프만-라 로슈 아게 스피로-피페리딘 유도체
MX2010007703A (es) * 2008-01-15 2010-09-14 Abbott Healthcare Products Bv Derivados de bifeprunox.
BR112019003811A2 (pt) 2016-08-26 2019-05-21 Exciva Ug (Haftungsbeschränkt) composição farmacêutica, método para aumentar os níveis plasmáticos de antagonista do receptor de nmda em um sujeito que precisa do mesmo, método para tratar uma doença ou transtorno em um sujeito que precisa do mesmo e uso da composição
WO2020022431A1 (ja) * 2018-07-27 2020-01-30 中国塗料株式会社 防汚塗料組成物、防汚塗膜、防汚塗膜付き基材及びその製造方法、並びに補修方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60126275A (ja) * 1983-12-13 1985-07-05 Otsuka Pharmaceut Co Ltd ベンゾチアゾ−ル誘導体
FR2567884B1 (fr) 1984-07-19 1987-03-06 Roussel Uclaf Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
EP0190472B1 (en) 1984-12-21 1989-07-12 Duphar International Research B.V New pharmaceutical compositions having anti-psychotic properties
EP0189612B1 (en) * 1984-12-21 1992-11-04 Duphar International Research B.V New pharmaceutical compositions having a psychotropic activity
DE4127849A1 (de) * 1991-08-22 1993-02-25 Merck Patent Gmbh Benzodioxanderivate
DE69736704T2 (de) * 1996-03-29 2007-09-13 Duphar International Research B.V. Piperazin- und piperidin- derivate
TW530054B (en) * 1997-09-24 2003-05-01 Duphar Int Res New piperazine and piperidine compounds
GB9811879D0 (en) * 1998-06-03 1998-07-29 Knoll Ag Therapeutic agents
UA71590C2 (en) * 1998-11-13 2004-12-15 Duphar Int Res Piperazine and piperidine derivatives
PT1283838E (pt) * 2000-05-12 2004-04-30 Solvay Pharm Bv Compostos de piperazina e de piperidina
EP1284731A1 (en) * 2000-05-12 2003-02-26 Solvay Pharmaceuticals B.V. Use of compounds having combined dopamine d2, 5-ht1a and alpha adrenoreceptor agonistic action for treating cns disorders

Also Published As

Publication number Publication date
BR0110592A (pt) 2003-04-01
ES2211809T3 (es) 2004-07-16
ZA200208537B (en) 2004-01-22
UA72337C2 (uk) 2005-02-15
TR200302294T4 (tr) 2004-02-23
EP1283838B1 (en) 2003-12-03
CA2405971C (en) 2010-03-30
PL198857B1 (pl) 2008-07-31
DE60101386D1 (de) 2004-01-15
CZ301464B6 (cs) 2010-03-10
NZ522116A (en) 2004-04-30
HK1055952A1 (en) 2004-01-30
PL358201A1 (en) 2004-08-09
EP1283838A1 (en) 2003-02-19
HUP0302016A2 (hu) 2003-09-29
PT1283838E (pt) 2004-04-30
DK1283838T3 (da) 2004-03-22
SK15872002A3 (sk) 2003-04-01
NO20025365L (no) 2002-11-08
AU2001263927B2 (en) 2004-09-30
NO20025365D0 (no) 2002-11-08
WO2001085725A1 (en) 2001-11-15
ATE255578T1 (de) 2003-12-15
CZ20023721A3 (cs) 2003-02-12
JP2003532729A (ja) 2003-11-05
SK286778B6 (sk) 2009-05-07
IL152177A0 (en) 2003-05-29
AU6392701A (en) 2001-11-20
AR028443A1 (es) 2003-05-07
MXPA02011084A (es) 2003-03-10
US20030119849A1 (en) 2003-06-26
US6911448B2 (en) 2005-06-28
CN1174979C (zh) 2004-11-10
CA2405971A1 (en) 2001-11-15
DE60101386T2 (de) 2004-05-27
RU2261250C2 (ru) 2005-09-27
CN1429226A (zh) 2003-07-09
IL152177A (en) 2009-08-03
DZ3370A1 (fr) 2001-11-15
US7297699B2 (en) 2007-11-20
US20060089366A1 (en) 2006-04-27

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