NO321717B1 - Fremgangsmate for identifikasjon av forbindelser med potensiale for behandling og forebyggelse av neoplasi. - Google Patents
Fremgangsmate for identifikasjon av forbindelser med potensiale for behandling og forebyggelse av neoplasi. Download PDFInfo
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- NO321717B1 NO321717B1 NO19982477A NO982477A NO321717B1 NO 321717 B1 NO321717 B1 NO 321717B1 NO 19982477 A NO19982477 A NO 19982477A NO 982477 A NO982477 A NO 982477A NO 321717 B1 NO321717 B1 NO 321717B1
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- Prior art keywords
- compound
- inhibitory activity
- neoplasia
- compounds
- treatment
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/533—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isomerase
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (2)
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| US08/866,027 US5858694A (en) | 1997-05-30 | 1997-05-30 | Method for identifying compounds for inhibition of cancerous lesions |
| US4673998A | 1998-03-24 | 1998-03-24 |
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| NO982477D0 NO982477D0 (no) | 1998-05-29 |
| NO982477L NO982477L (no) | 1998-12-01 |
| NO321717B1 true NO321717B1 (no) | 2006-06-26 |
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| NO19982477A NO321717B1 (no) | 1997-05-30 | 1998-05-29 | Fremgangsmate for identifikasjon av forbindelser med potensiale for behandling og forebyggelse av neoplasi. |
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| EP (2) | EP0881300B1 (xx) |
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| TR (1) | TR199800960A3 (xx) |
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| IL132366A0 (en) * | 1998-10-15 | 2001-03-19 | Cell Pathways Inc | Methods for identifying compounds for inhibition of neoplastic lesions and pharmaceutical compositions containing such compounds |
| US20040009464A1 (en) * | 1998-10-15 | 2004-01-15 | Li Liu | Methods for identifying compounds for inhibition of neoplastic lesions, and pharmacetical compositions containing such compounds |
| US20020009764A1 (en) * | 1999-10-08 | 2002-01-24 | W. Joseph Thompson | Methods for identifying compounds for inhibition of neoplastic lesions, and pharmaceutical compositions containing such compounds |
| US20050244914A1 (en) * | 1999-10-08 | 2005-11-03 | Li Liu | Methods for identifying compounds for inhibition of neoplastic lesions, and pharmaceutical compositions containing such compounds |
| DE10060388A1 (de) * | 2000-12-05 | 2002-06-06 | Merck Patent Gmbh | Verwendung von Pyrazolo [4,3-d]pyrimidinen |
| FR2824334B1 (fr) | 2001-05-03 | 2003-10-10 | Coletica | Procede pour tester une substance eventuellement active dans le domaine de la lipolyse et son utilisation principalement cosmetique |
| JP2005516586A (ja) * | 2001-07-20 | 2005-06-09 | ボード オブ トラスティーズ オブ ザ ユニヴァースティ オブ イリノイ | 癌の処置に対する遺伝子標的を同定するための試薬および方法 |
| DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| JP2004536614A (ja) * | 2001-08-01 | 2004-12-09 | ユニバーシティ オブ ユタ | Ｐｄｅ３環状ヌクレオチド・ホスホジエステラーゼのアイソフォーム選択的な阻害剤および活性化剤 |
| WO2003038430A1 (fr) * | 2001-10-29 | 2003-05-08 | Takeda Chemical Industries, Ltd. | Technique d'analyse |
| US20050048573A1 (en) * | 2003-02-03 | 2005-03-03 | Plexxikon, Inc. | PDE5A crystal structure and uses |
| US7711584B2 (en) | 2003-09-04 | 2010-05-04 | Hartford Fire Insurance Company | System for reducing the risk associated with an insured building structure through the incorporation of selected technologies |
| JPWO2005054181A1 (ja) * | 2003-12-01 | 2007-12-06 | 株式会社リバース・プロテオミクス研究所 | 抗癌剤の新規標的タンパク質および対応する新規抗癌剤（スプナール） |
| JP2008503446A (ja) | 2004-05-06 | 2008-02-07 | プレキシコン，インコーポレーテッド | Ｐｄｅ４ｂ阻害剤及びその使用 |
| CA2583428A1 (en) * | 2004-09-03 | 2006-03-09 | Plexxikon, Inc. | Bicyclic heteroaryl pde4b inhibitors |
| WO2006074443A2 (en) | 2005-01-07 | 2006-07-13 | The Johns Hopkins University | Pde5 inhibitor compositions and methods for immunotherapy |
| US20080171746A1 (en) * | 2005-03-14 | 2008-07-17 | Thomas Klein | Method for Preventing Cardiovascular Diseases |
| AU2007205208B2 (en) * | 2006-01-04 | 2012-11-01 | Southern Research Institute | Derivatives of sulindac, use thereof and preparation thereof |
| JP2007224007A (ja) * | 2006-03-27 | 2007-09-06 | Univ De Santiago De Compostela | ｙｅｓｓｏｔｏｘｉｎｓのヒト腫瘍細胞増殖抑制剤としての治療的な使用 |
| US8673914B2 (en) | 2011-03-28 | 2014-03-18 | St. John's University | Use of phosphodiesterase inhibitors for treating multidrug resistance |
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1998
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- 1998-05-25 TW TW087108072A patent/TW591111B/zh not_active IP Right Cessation
- 1998-05-28 CZ CZ19981651A patent/CZ295868B6/cs not_active IP Right Cessation
- 1998-05-28 KR KR1019980019380A patent/KR100304859B1/ko not_active IP Right Cessation
- 1998-05-29 AU AU69794/98A patent/AU709666B2/en not_active Ceased
- 1998-05-29 EP EP98304247A patent/EP0881300B1/en not_active Expired - Lifetime
- 1998-05-29 TR TR1998/00960A patent/TR199800960A3/tr unknown
- 1998-05-29 DE DE0881300T patent/DE881300T1/de active Pending
- 1998-05-29 AT AT98304247T patent/ATE198771T1/de not_active IP Right Cessation
- 1998-05-29 JP JP10150033A patent/JP3053381B2/ja not_active Expired - Fee Related
- 1998-05-29 DE DE69800488T patent/DE69800488T2/de not_active Expired - Lifetime
- 1998-05-29 EP EP00112020A patent/EP1038523A3/en not_active Withdrawn
- 1998-05-29 IL IL12469998A patent/IL124699A/xx not_active IP Right Cessation
- 1998-05-29 ES ES98304247T patent/ES2132055T3/es not_active Expired - Lifetime
- 1998-05-29 NO NO19982477A patent/NO321717B1/no unknown
- 1998-05-29 DK DK98304247T patent/DK0881300T3/da active
- 1998-12-16 HK HK98113546A patent/HK1012196A1/xx not_active IP Right Cessation
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1999
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- 1999-10-08 US US09/414,625 patent/US6500610B1/en not_active Expired - Fee Related
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2000
- 2000-02-22 JP JP2000044184A patent/JP2000198746A/ja active Pending
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2002
- 2002-01-07 US US10/040,776 patent/US20030004093A1/en not_active Abandoned
- 2002-09-24 US US10/252,983 patent/US20030190686A1/en not_active Abandoned
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