NO321077B1 - Isolert DNA-segment som koder for forgrenet alfa-ketosyredehydrogenasekompleks, rekombinant DNA som omfatter DNA-segmentet, vertscelle og plasmid som omfatter rekombinant DNA, samt polypeptid. - Google Patents

Isolert DNA-segment som koder for forgrenet alfa-ketosyredehydrogenasekompleks, rekombinant DNA som omfatter DNA-segmentet, vertscelle og plasmid som omfatter rekombinant DNA, samt polypeptid. Download PDF

Info

Publication number
NO321077B1
NO321077B1 NO19960372A NO960372A NO321077B1 NO 321077 B1 NO321077 B1 NO 321077B1 NO 19960372 A NO19960372 A NO 19960372A NO 960372 A NO960372 A NO 960372A NO 321077 B1 NO321077 B1 NO 321077B1
Authority
NO
Norway
Prior art keywords
sequence
dna
plasmid
alpha
avermitilis
Prior art date
Application number
NO19960372A
Other languages
English (en)
Norwegian (no)
Other versions
NO960372D0 (no
NO960372L (no
Inventor
Claudio Daniel Denoya
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO960372D0 publication Critical patent/NO960372D0/no
Publication of NO960372L publication Critical patent/NO960372L/no
Publication of NO321077B1 publication Critical patent/NO321077B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/040043-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (1.2.4.4), i.e. branched-chain-alpha-ketoacid dehydrogenase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
NO19960372A 1993-07-30 1996-01-29 Isolert DNA-segment som koder for forgrenet alfa-ketosyredehydrogenasekompleks, rekombinant DNA som omfatter DNA-segmentet, vertscelle og plasmid som omfatter rekombinant DNA, samt polypeptid. NO321077B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10051893A 1993-07-30 1993-07-30
PCT/IB1994/000127 WO1995004150A1 (en) 1993-07-30 1994-05-30 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis

Publications (3)

Publication Number Publication Date
NO960372D0 NO960372D0 (no) 1996-01-29
NO960372L NO960372L (no) 1996-01-29
NO321077B1 true NO321077B1 (no) 2006-03-13

Family

ID=22280171

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19960372A NO321077B1 (no) 1993-07-30 1996-01-29 Isolert DNA-segment som koder for forgrenet alfa-ketosyredehydrogenasekompleks, rekombinant DNA som omfatter DNA-segmentet, vertscelle og plasmid som omfatter rekombinant DNA, samt polypeptid.
NO20052209A NO20052209D0 (no) 1993-07-30 2005-05-04 Fremgansmate for fremstilling av nytt og naturlig avermektin

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20052209A NO20052209D0 (no) 1993-07-30 2005-05-04 Fremgansmate for fremstilling av nytt og naturlig avermektin

Country Status (22)

Country Link
US (1) US5728561A (fi)
EP (1) EP0711349B1 (fi)
JP (1) JP2807348B2 (fi)
KR (1) KR100221385B1 (fi)
CN (2) CN1104502C (fi)
AT (1) ATE248916T1 (fi)
AU (2) AU6657294A (fi)
BR (1) BR9407211A (fi)
CA (1) CA2167520C (fi)
CZ (3) CZ26096A3 (fi)
DE (1) DE69433112T2 (fi)
DK (1) DK0711349T3 (fi)
ES (1) ES2204914T3 (fi)
FI (1) FI960401A (fi)
HU (1) HU218964B (fi)
IL (2) IL110430A (fi)
NO (2) NO321077B1 (fi)
NZ (2) NZ266014A (fi)
PL (3) PL181778B1 (fi)
PT (1) PT711349E (fi)
WO (1) WO1995004150A1 (fi)
ZA (1) ZA945639B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466102A (en) * 1993-12-16 1995-11-14 Kennametal Inc. System for coupling machine tools
US6143561A (en) * 1997-06-30 2000-11-07 The Curators Of The University Of Missouri DNA encoding plastid pyruvate dehydrogenase and branched chain oxoacid dehydrogenase components
US6248579B1 (en) 1998-02-13 2001-06-19 Pfizer Inc Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
US6197591B1 (en) 1998-09-14 2001-03-06 Pfizer Inc. Streptomyces avermitilis regulatory genes for increased avermectin production
WO2001012821A1 (en) * 1999-08-12 2001-02-22 Pfizer Products Inc. Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
EP1210460B1 (en) * 1999-08-19 2007-05-23 Omniscience Pharmaceuticals Gene cloning
CN1321752A (zh) * 2000-04-29 2001-11-14 上海博德基因开发有限公司 一种新的多肽——人分支alpha-酮酸脱氢酶E1-beta亚单位9和编码这种多肽的多核苷酸
CN1321684A (zh) * 2000-04-29 2001-11-14 上海博德基因开发有限公司 一种新的多肽——人krab包含的锌指蛋白kraz2-12和编码这种多肽的多核苷酸
AT410217B (de) * 2000-06-15 2003-03-25 Cistem Biotechnologies Gmbh Vektor und ein verfahren zur expression und selektion randomisierter peptid-sequenzen
EP2141236A1 (en) 2008-07-03 2010-01-06 KRKA, D.D., Novo Mesto Process for production of lipstatin and microorganisms therefore
CN112410389B (zh) * 2019-08-23 2023-07-18 中国科学院微生物研究所 支链α-酮酸脱氢酶复合体在制备丙二酸单酰辅酶A中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN167980B (fi) * 1987-01-23 1991-01-19 Pfizer
EP0284176B1 (en) * 1987-01-23 1993-08-25 Pfizer Inc. Process for production of avermectins and cultures therefor

Also Published As

Publication number Publication date
CN1128046A (zh) 1996-07-31
IL110430A0 (en) 1994-10-21
FI960401A0 (fi) 1996-01-29
NZ328926A (en) 1998-02-26
ES2204914T3 (es) 2004-05-01
NO20052209L (no) 1996-01-29
CZ26096A3 (en) 1996-05-15
ZA945639B (en) 1996-01-29
CZ20002929A3 (cs) 2001-11-14
DE69433112T2 (de) 2004-04-01
PL181916B1 (en) 2001-10-31
IL110430A (en) 2005-08-31
FI960401A (fi) 1996-01-29
AU9421898A (en) 1999-03-04
US5728561A (en) 1998-03-17
NO960372D0 (no) 1996-01-29
EP0711349A1 (en) 1996-05-15
WO1995004150A1 (en) 1995-02-09
ATE248916T1 (de) 2003-09-15
CZ289136B6 (cs) 2001-11-14
DK0711349T3 (da) 2003-11-24
BR9407211A (pt) 1996-09-17
PL181778B1 (pl) 2001-09-28
PL312733A1 (en) 1996-05-13
PT711349E (pt) 2003-12-31
PL177922B1 (pl) 2000-01-31
CA2167520A1 (en) 1995-02-09
NZ266014A (en) 1997-11-24
JP2807348B2 (ja) 1998-10-08
JPH08507931A (ja) 1996-08-27
CN1104502C (zh) 2003-04-02
DE69433112D1 (de) 2003-10-09
CA2167520C (en) 1999-07-27
CZ289866B6 (cs) 2002-04-17
NO20052209D0 (no) 2005-05-04
IL154136A0 (en) 2003-07-31
AU712442B2 (en) 1999-11-04
HU218964B (hu) 2001-01-29
AU6657294A (en) 1995-02-28
HUT71323A (en) 1995-11-28
NO960372L (no) 1996-01-29
CN1208078A (zh) 1999-02-17
HU9402192D0 (en) 1994-10-28
KR100221385B1 (ko) 1999-10-01
EP0711349B1 (en) 2003-09-03

Similar Documents

Publication Publication Date Title
US6399324B1 (en) Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from Streptomyces avermitilis
Fischer et al. Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis
US8030045B2 (en) Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
NO321077B1 (no) Isolert DNA-segment som koder for forgrenet alfa-ketosyredehydrogenasekompleks, rekombinant DNA som omfatter DNA-segmentet, vertscelle og plasmid som omfatter rekombinant DNA, samt polypeptid.
US20150211035A1 (en) Biological method for producing cis-5-hydroxy-l-pipecolic acid
Skinner et al. Cloning and sequencing of a cluster of genes encoding branched-chain alpha-keto acid dehydrogenase from Streptomyces avermitilis and the production of a functional E1 [alpha beta] component in Escherichia coli
US5707839A (en) Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
AU2309701A (en) Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
Snoep et al. Catabolism of Branched-Chain
CN113337485A (zh) 一种抗噬菌体和抗病毒系统
WO2004033695A2 (en) A promoter from streptomyces coelicolor